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Challenges and future directions in therapeutics for pancreatic ductal adenocarcinoma

, RN BSN MSHRM & , PhD FRC Path

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Dimitra Grapsa, Konstantinos Syrigos & Muhammad Wasif Saif. (2016) Nanoliposomal irinotecan for treating pancreatic cancer. Expert Opinion on Orphan Drugs 4:5, pages 541-547.
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Suravi Pramanik, Yingling Chen, Heyu Song, Irine Khutsishvili, Luis A Marky, Sutapa Ray, Amarnath Natarajan, Pankaj K Singh & Kishor K Bhakat. (2022) The human AP-endonuclease 1 (APE1) is a DNA G-quadruplex structure binding protein and regulates KRAS expression in pancreatic ductal adenocarcinoma cells . Nucleic Acids Research 50:6, pages 3394-3412.
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Shailendra K. Gautam, Vipin Dalal, Maneesh Jain & Surinder K. Batra. 2022. Systemic Drug Delivery Strategies. Systemic Drug Delivery Strategies 437 461 .
Qiang Yan, Chenming Ni, Yingying Lin, Xu Sun, Zhenhua Shen, Minjie Zhang, Shuwen Han, Jiemin Shi, Jing Mao, Zhe Yang & Weilin Wang. (2021) ELK1 Enhances Pancreatic Cancer Progression Via LGMN and Correlates with Poor Prognosis. Frontiers in Molecular Biosciences 8.
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K. Sudhakara Prasad, Yousef Abugalyon, Chunqiang Li, Feng Xu & XiuJun Li. (2020) A new method to amplify colorimetric signals of paper-based nanobiosensors for simple and sensitive pancreatic cancer biomarker detection. The Analyst 145:15, pages 5113-5117.
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Wenying Yan, Xingyi Liu, Yibo Wang, Shuqing Han, Fan Wang, Xin Liu, Fei Xiao & Guang Hu. (2020) Identifying Drug Targets in Pancreatic Ductal Adenocarcinoma Through Machine Learning, Analyzing Biomolecular Networks, and Structural Modeling. Frontiers in Pharmacology 11.
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Claudia Di Carlo, Jessica Brandi & Daniela Cecconi. (2018) Pancreatic cancer stem cells: Perspectives on potential therapeutic approaches of pancreatic ductal adenocarcinoma. World Journal of Stem Cells 10:11, pages 172-182.
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E. A. Dubtsova, L. V. Vinokurova, K. A. Nikolskaya, M. A. Kiryukova & D. S. Bordin. (2018) Chronic pancreatitis as a risk factor for pancreatic cancer (a clinical case). Almanac of Clinical Medicine 46:5, pages 542-549.
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Qiang Yan, Wen-Bin Yuan, Xu Sun, Ming-Jie Zhang, Feng Cen, Shi-Yu Zhou, Wan-Bo Wu, Yong‑Can Xu, Li-Hui Tong & Zhi-Hong Ma. (2018) Asparaginyl endopeptidase enhances pancreatic ductal adenocarcinoma cell invasion in an exosome-dependent manner and correlates with poor prognosis. International Journal of Oncology.
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Chiara Birtolo, Vay Liang W. Go, Andrzej Ptasznik, Guido Eibl & Stephen J. Pandol. (2016) Phosphatidylinositol 3-Kinase. Pancreas 45:1, pages 21-31.
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Maria Marlow, Mohammed Al-Ameedee, Thomas Smith, Simon Wheeler & Michael J. Stocks. (2015) Linifanib – a multi-targeted receptor tyrosine kinase inhibitor and a low molecular weight gelator. Chemical Communications 51:29, pages 6384-6387.
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