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Drug Evaluation

Entinostat (SNDX-275) for the treatment of non-small cell lung cancer

, MD, , MD FACP FCCP (Director, Clinical Associate Professor of Medicine) & (Head of Phase I - Early Clinical Trials Unit)

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Ashwin Somasundaram & Timothy F Burns. (2017) Pembrolizumab in the treatment of metastatic non-small-cell lung cancer: patient selection and perspectives. Lung Cancer: Targets and Therapy 8, pages 1-11.
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Articles from other publishers (32)

Yu Jing, Ziming Mao, Jing Zhu, Xirui Ma, Huifang Liu & Fengling Chen. (2023) TRAIP serves as a potential prognostic biomarker and correlates with immune infiltrates in lung adenocarcinoma. International Immunopharmacology 122, pages 110605.
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Li-Chan Lin, Bin Tu, Kai Song, Zhi-Yan Liu, He Sun, Yang Zhou, Ji-Ming Sha, Jing-Jing Yang, Ye Zhang, Jian-Yuan Zhao & Hui Tao. (2023) Mitochondrial quality control in cardiac fibrosis: Epigenetic mechanisms and therapeutic strategies. Metabolism 145, pages 155626.
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Edoardo D'Angelo, Chiara Pastrello, Andrea Biccari, Asia Marangio, Francesca Sensi, Sara Crotti, Matteo Fassan, Igor Jurisica, Salvatore Pucciarelli & Marco Agostini. (2023) An integrated multiomics analysis of rectal cancer patients identified POU2F3 as a putative druggable target and entinostat as a cytotoxic enhancer of 5‐fluorouracil . International Journal of Cancer 153:2, pages 437-449.
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Pooja Gulhane & Shailza Singh. (2023) Unraveling the Post-Translational Modifications and therapeutical approach in NSCLC pathogenesis. Translational Oncology 33, pages 101673.
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Shabir Ahmad Ganai, Basit Amin Shah & Manzoor Ahmad Yatoo. 2023. Epigenetic Regulation of Cancer in Response to Chemotherapy. Epigenetic Regulation of Cancer in Response to Chemotherapy 163 198 .
Jingru Yang, Cong Song & Xianquan Zhan. (2022) The role of protein acetylation in carcinogenesis and targeted drug discovery. Frontiers in Endocrinology 13.
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Elisabetta Di Bello, Beatrice Noce, Rossella Fioravanti, Clemens Zwergel, Sergio Valente, Dante Rotili, Giulia Fianco, Daniela Trisciuoglio, Marina M. Mourão, Policarpo SalesJr.Jr., Suzanne Lamotte, Eric Prina, Gerald F. Späth, Cécile Häberli, Jennifer Keiser & Antonello Mai. (2022) Effects of Structurally Different HDAC Inhibitors against Trypanosoma cruzi , Leishmania , and Schistosoma mansoni . ACS Infectious Diseases 8:7, pages 1356-1366.
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Min-Ru Jiao, Bo Han, Xiu Gu, Hao Zhang, Ai-Ping Wang & Qing-Wei Zhang. (2022) Design, Synthesis, and Evaluation of Benzoheterocyclic-Containing Derivatives as Novel HDAC1 Inhibitors. Pharmaceutical Fronts 04:01, pages e22-e29.
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Yudan Cui, Jingshan Cai, Wenxin Wang & Shengjun Wang. (2021) Regulatory Effects of Histone Deacetylase Inhibitors on Myeloid-Derived Suppressor Cells. Frontiers in Immunology 12.
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Yvonne L. Chao & Chad V. Pecot. (2021) Targeting Epigenetics in Lung Cancer. Cold Spring Harbor Perspectives in Medicine 11:6, pages a038000.
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Liyun Luo, Zhijie Zhang, Ni Qiu, Li Ling, Xiaoting Jia, Ying Song, Hongsheng Li, Jiansheng Li, Hui Lyu, Hao Liu, Zhimin He, Bolin Liu & Guopei Zheng. (2021) Disruption of FOXO3a-miRNA feedback inhibition of IGF2/IGF-1R/IRS1 signaling confers Herceptin resistance in HER2-positive breast cancer. Nature Communications 12:1.
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Mohammed Ghiboub, Ahmed M. I. Elfiky, Menno P. J. de Winther, Nicola R. Harker, David F. Tough & Wouter J. de Jonge. (2021) Selective Targeting of Epigenetic Readers and Histone Deacetylases in Autoimmune and Inflammatory Diseases: Recent Advances and Future Perspectives. Journal of Personalized Medicine 11:5, pages 336.
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Wen-juan Liu, Yue Du, Ru Wen, Ming Yang & Jian Xu. (2020) Drug resistance to targeted therapeutic strategies in non-small cell lung cancer. Pharmacology & Therapeutics 206, pages 107438.
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Shanshan Ma, Tengfei Liu, Ling Xu, Yaping Wang, Jiankang Zhou, Tuanjie Huang, Peng Li, Hongtao Liu, Yanting Zhang, Xinkui Zhou, Yuanbo Cui, Xingxing Zang, Yuming Wang & Fangxia Guan. (2019) Histone deacetylases inhibitor MS‐275 suppresses human esophageal squamous cell carcinoma cell growth and progression via the PI3K/Akt/mTOR pathway. Journal of Cellular Physiology 234:12, pages 22400-22410.
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Zhiqiang Ma, Dong Liu, Shouyin Di, Zhipei Zhang, Weimiao Li, Jiao Zhang, Liqun Xu, Kai Guo, Yifang Zhu, Xiaofei Li, Jing Han & Xiaolong Yan. (2019) Histone deacetylase 9 downregulation decreases tumor growth and promotes apoptosis in non‐small cell lung cancer after melatonin treatment. Journal of Pineal Research 67:2.
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Yong-Tao Duan, Chetan B. Sangani, Wei Liu, Kunjal V. Soni & Yongfang Yao. (2019) New Promises to Cure Cancer and Other Genetic Diseases/Disorders: Epi-drugs Through Epigenetics. Current Topics in Medicinal Chemistry 19:12, pages 972-994.
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Veronika A. Myasoedova, Vasily Sukhorukov, Andrey V. Grechko, Dongwei Zhang, Elena Romanenko, Vawain Orekhov & Alexander N. Orekhov. (2019) Inhibitors of DNA Methylation and Histone Deacetylation as Epigenetically Active Drugs for Anticancer Therapy. Current Pharmaceutical Design 25:6, pages 635-641.
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Bai‐Ling Luo, Yan Zhou, Hui Lv, Sheng‐Hua Sun & Wen‐Xiang Tang. (2019) MS‐275 potentiates the effect of YM‐155 in lung adenocarcinoma via survivin downregulation induced by miR‐138 and miR‐195. Thoracic Cancer 10:6, pages 1355-1368.
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Xian Zhang, Dakshesh Patel, Qin Xu & Richard Veenstra. (2018) Differences in Functional Expression of Connexin43 and NaV1.5 by Pan- and Class-Selective Histone Deacetylase Inhibition in Heart. International Journal of Molecular Sciences 19:8, pages 2288.
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Ping Gong, Kun Li, Ying Li, Dan Liu, Linxiang Zhao & Yongkui Jing. (2018) HDAC and Ku70 axis- an effective target for apoptosis induction by a new 2-cyano-3-oxo-1,9-dien glycyrrhetinic acid analogue. Cell Death & Disease 9:6.
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Xiangju YinQian WuJitender MongaEnjun XieHao WangShufen WangHuizhen ZhangZhan-You WangTianhua ZhouYujun ShiJack RogersHening LinJunxia MinFudi Wang. (2018) HDAC1 Governs Iron Homeostasis Independent of Histone Deacetylation in Iron-Overload Murine Models. Antioxidants & Redox Signaling 28:13, pages 1224-1237.
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E T Aristizabal Prada & C J Auernhammer. (2018) Targeted therapy of gastroenteropancreatic neuroendocrine tumours: preclinical strategies and future targets. Endocrine Connections 7:1, pages R1-R25.
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Zhong‑Tian Bai, Bing Bai, Jun Zhu, Cui‑Xia Di, Xun Li & Wen‑Ce Zhou. (2017) Epigenetic actions of environmental factors and promising drugs for cancer therapy (Review). Oncology Letters.
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Ashwin Somasundaram & Timothy F. Burns. (2017) The next generation of immunotherapy: keeping lung cancer in check. Journal of Hematology & Oncology 10:1.
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Josep Mari-Alexandre, Angel Diaz-Lagares, Maria Villalba, Oscar Juan, Ana B. Crujeiras, Alfonso Calvo & Juan Sandoval. (2017) Translating cancer epigenomics into the clinic: focus on lung cancer. Translational Research 189, pages 76-92.
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Qingwei Zhang, Bingliu Lu & Jianqi Li. (2017) Design, synthesis and biological evaluation of 4-piperazinyl-containing Chidamide derivatives as HDACs inhibitors. Bioorganic & Medicinal Chemistry Letters 27:14, pages 3162-3166.
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Jiunn-Min Shieh, Yen-An Tang, Fu-Han Hu, Wei-Jan Huang, Ying-Jan Wang, Jayu Jen, Sheng-You Liao, Ying-Hung Lu, Ya-Ling Yeh, Tseng-Wei Wang, Pinpin Lin & Yi-Ching Wang. (2017) A histone deacetylase inhibitor enhances expression of genes inhibiting Wnt pathway and augments activity of DNA demethylation reagent against nonsmall-cell lung cancer. International Journal of Cancer 140:10, pages 2375-2386.
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Zihao Liu, Andrew J. Sanders, Gehao Liang, Erwei Song, Wen G. Jiang & Chang Gong. (2017) Hey Factors at the Crossroad of Tumorigenesis and Clinical Therapeutic Modulation of Hey for Anticancer Treatment. Molecular Cancer Therapeutics 16:5, pages 775-786.
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Mudassier Ahmad, Mushtaq A. Aga, Javeed Ahmad Bhat, Brijesh Kumar, Abdul Rouf, Neena Capalash, Mubashir Javeed Mintoo, Ashok Kumar, Priya Mahajan, Dilip Manikrao Mondhe, Amit Nargotra, Parduman Raj Sharma, Mohmmad Afzal Zargar, Ram A. Vishwakarma, Bhahwal Ali Shah, Subhash Chandra Taneja & Abid Hamid. (2017) Exploring Derivatives of Quinazoline Alkaloid l -Vasicine as Cap Groups in the Design and Biological Mechanistic Evaluation of Novel Antitumor Histone Deacetylase Inhibitors . Journal of Medicinal Chemistry 60:8, pages 3484-3497.
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Marilena Colaianna, Sten Ilmjärv, Hedi Peterson, Ilse Kern, Stephanie Julien, Mathurin Baquié, Giorgia Pallocca, Sieto Bosgra, Agapios Sachinidis, Jan G. Hengstler, Marcel Leist & Karl-Heinz Krause. (2016) Fingerprinting of neurotoxic compounds using a mouse embryonic stem cell dual luminescence reporter assay. Archives of Toxicology 91:1, pages 365-391.
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Li-Li Jiang, Shi-Juan Zhou, Xue-Min Zhang, Hai-Qing Chen & Wei Liu. (2016) Sulforaphane suppresses in vitro and in vivo lung tumorigenesis through downregulation of HDAC activity. Biomedicine & Pharmacotherapy 78, pages 74-80.
Crossref
Aamir Ahmad. 2016. Lung Cancer and Personalized Medicine: Novel Therapies and Clinical Management. Lung Cancer and Personalized Medicine: Novel Therapies and Clinical Management 111 122 .

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