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Miscellaneous

Recent advances in our understanding of protein conformational stability from a pharmaceutical perspective

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Pages 1493-1500 | Published online: 23 Feb 2005

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Deborah S. Goldberg, Steven M. Bishop, Ambarish U. Shah & Hasige A Sathish. (2011) Formulation Development of Therapeutic Monoclonal Antibodies Using High-Throughput Fluorescence and Static Light Scattering Techniques: Role of Conformational and Colloidal Stability. Journal of Pharmaceutical Sciences 100:4, pages 1306-1315.
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Yi Li, William F. WeissIVIV & Christopher J. Roberts. (2009) Characterization of High-Molecular-Weight Nonnative Aggregates and Aggregation Kinetics by Size Exclusion Chromatography With Inline Multi-Angle Laser Light Scattering. Journal of Pharmaceutical Sciences 98:11, pages 3997-4016.
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Christopher J. Roberts, Richard T. Darrington & Maureen B. Whitley. (2003) Irreversible aggregation of recombinant bovine granulocyte-colony stimulating factor (bG-CSF) and implications for predicting protein shelf life. Journal of Pharmaceutical Sciences 92:5, pages 1095-1111.
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Christopher J. Roberts. (2003) Kinetics of Irreversible Protein Aggregation:  Analysis of Extended Lumry−Eyring Models and Implications for Predicting Protein Shelf Life. The Journal of Physical Chemistry B 107:5, pages 1194-1207.
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Donald S. Maclean, Quansheng Qian & C.Russell Middaugh. (2002) Stabilization of proteins by low molecular weight multi‐ions. Journal of Pharmaceutical Sciences 91:10, pages 2220-2229.
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