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Expert Opinion on Investigational Drugs Volume 9, 2000 - Issue 4
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Drug Evaluation

An assessment of rufinamide as an anti-epileptic in comparison with other drugs in clinical development

Kewal K Jain Biotech, Bläsiring 7, CH-4057 Basel, Switzerland. [email protected]
Pages 829-840 | Published online: 24 Feb 2005

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Read on this site (3)

Colin D Ferrie. (2010) Rufinamide: a new antiepileptic drug treatment for Lennox–Gastaut syndrome. Expert Review of Neurotherapeutics 10:6, pages 851-860.
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Meir Bialer. (2006) New antiepileptic drugs that are second generation to existing antiepileptic drugs. Expert Opinion on Investigational Drugs 15:6, pages 637-647.
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Kewal K Jain. (2000) An assessment of zonisamide as an anti-epileptic drug. Expert Opinion on Pharmacotherapy 1:6, pages 1245-1260.
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Articles from other publishers (20)

Graeme J. Sills. (2023) Pharmacological diversity amongst approved and emerging antiseizure medications for the treatment of developmental and epileptic encephalopathies. Therapeutic Advances in Neurological Disorders 16.
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Andreas Schulze-Bonhage. (2019) „Orphan drugs“ in der EpileptologieOrphan drugs in epileptology. Zeitschrift für Epileptologie 32:4, pages 277-285.
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Pasquale Striano, Rob McMurray, Estevo Santamarina & Mercè Falip. (2018) Rufinamide for the treatment of Lennox‐Gastaut syndrome: evidence from clinical trials and clinical practice. Epileptic Disorders 20:1, pages 13-29.
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Marina Nikanorova, Christian Brandt, Stéphane Auvin & Rob McMurray. (2017) Real-world data on rufinamide treatment in patients with Lennox–Gastaut syndrome: Results from a European noninterventional registry study. Epilepsy & Behavior 76, pages 63-70.
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민소윤, 서효림, 권순학, 황수경, 이윤정, 조태경 & 노다은. (2017) Effectiveness and Tolerability of Rufinamide in Korean Children with Lennox-Gastaut Syndrome. Journal of the korean child neurology society 25:2, pages 89-92.
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Wojciech P. Oziminski. (2016) The kinetics of water-assisted tautomeric 1,2-proton transfer in azoles: a computational approach. Structural Chemistry 27:6, pages 1845-1854.
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Rob McMurray & Pasquale Striano. (2016) Treatment of Adults with Lennox?Gastaut Syndrome: Further Analysis of Efficacy and Safety/Tolerability of Rufinamide. Neurology and Therapy 5:1, pages 35-43.
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Andrew Bell, Wolfgang Fecke & Christine Williams. 2015. Attrition in the Pharmaceutical Industry. Attrition in the Pharmaceutical Industry 229 263 .
David C Swinney & Shuangluo Xia. (2014) The discovery of medicines for rare diseases. Future Medicinal Chemistry 6:9, pages 987-1002.
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David C. Swinney. (2013) The Contribution of Mechanistic Understanding to Phenotypic Screening for First-in-Class Medicines. SLAS Discovery 18:10, pages 1186-1192.
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J. Helen Cross, Gerhard Kluger & Lieven Lagae. (2013) Advancing the management of childhood epilepsies. European Journal of Paediatric Neurology 17:4, pages 334-347.
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Wojciech P. Oziminski. (2013) Theoretical study on the solvent influence on 1,2,3-triazole tautomeric equilibrium. A comparison of incremental microsolvation and continuum solvation model approaches. Tetrahedron 69:15, pages 3197-3205.
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Meir Bialer. (2012) Chemical properties of antiepileptic drugs (AEDs). Advanced Drug Delivery Reviews 64:10, pages 887-895.
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David C. Swinney & Jason Anthony. (2011) How were new medicines discovered?. Nature Reviews Drug Discovery 10:7, pages 507-519.
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Kenneth R. Kaufman & Peter J. Struck. (2011) Activation of suicidal ideation with adjunctive rufinamide in bipolar disorder. Epilepsy & Behavior 20:2, pages 386-389.
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G. Kluger, T. Glauser, G. Krauss, R. Seeruthun, C. Perdomo & S. Arroyo. (2010) Adjunctive rufinamide in Lennox-Gastaut syndrome: a long-term, open-label extension study. Acta Neurologica Scandinavica 122:3, pages 202-208.
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Christian E. Elger, Hermann Stefan, Allison Mann, Milind Narurkar, Yijun Sun & Carlos Perdomo. (2010) A 24-week multicenter, randomized, double-blind, parallel-group, dose-ranging study of rufinamide in adults and adolescents with inadequately controlled partial seizures. Epilepsy Research 88:2-3, pages 255-263.
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Gerhard Kluger, Gerhard Kurlemann, Edda Haberlandt, Jan-Peter Ernst, Uwe Runge, Felix Schneider, Christine Makowski, Rainer Boor & Thomas Bast. (2009) Effectiveness and tolerability of rufinamide in children and adults with refractory epilepsy: First European experience. Epilepsy & Behavior 14:3, pages 491-495.
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V. Biton. 2004. The Treatment of Epilepsy. The Treatment of Epilepsy 500 506 .
R.R Leker & M.Y Neufeld. (2003) Anti-epileptic drugs as possible neuroprotectants in cerebral ischemia. Brain Research Reviews 42:3, pages 187-203.
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