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Review

Small molecule αv integrin antagonists: novel anticancer agents

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Pages 1271-1279 | Published online: 24 Feb 2005

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Stephan Huveneers, Hoa Truong & Erik H. J. Danen. (2007) Integrins: Signaling, disease, and therapy. International Journal of Radiation Biology 83:11-12, pages 743-751.
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Le T Duong & Paul J Coleman. (2002) Ligands to the integrin receptor αvβ3. Expert Opinion on Therapeutic Patents 12:7, pages 1009-1021.
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Erik W Thompson & John T Price. (2002) Mechanisms of tumour invasion and metastasis: emerging targets for therapy. Expert Opinion on Therapeutic Targets 6:2, pages 217-233.
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Richard D Connell & Jean S Beebe. (2001) Patent focus on cancer chemotherapeutics. II Angiogenesis agents: April 2000 - September 2000. Expert Opinion on Therapeutic Patents 11:1, pages 77-114.
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Oliver Stoeltzing, Wenbiao Liu, Niels Reinmuth, Fan Fan, Graham C. Parry, Alexander A. Parikh, Marya F. McCarty, Corazon D. Bucana, Andrew P. Mazar & Lee M. Ellis. (2003) Inhibition of integrin ?5?1 function with a small peptide (ATN-161) plus continuous 5-FU infusion reduces colorectal liver metastases and improves survival in mice. International Journal of Cancer 104:4, pages 496-503.
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Devin S. Gary, Ollivier Milhavet, Simonetta Camandola & Mark P. Mattson. (2003) Essential role for integrin linked kinase in Akt-mediated integrin survival signaling in hippocampal neurons. Journal of Neurochemistry 84:4, pages 878-890.
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Lars Dyrskjøt, Thomas Thykjaer, Mogens Kruhøffer, Jens Ledet Jensen, Niels Marcussen, Stephen Hamilton-Dutoit, Hans Wolf & Torben F. Ørntoft. (2002) Identifying distinct classes of bladder carcinoma using microarrays. Nature Genetics 33:1, pages 90-96.
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Françoise Perron-Sierra, Dominique Saint Dizier, Marc Bertrand, Annie Genton, Gordon C Tucker & Patrick Casara. (2002) Substituted benzocyloheptenes as potent and selective αv integrin antagonists. Bioorganic & Medicinal Chemistry Letters 12:22, pages 3291-3296.
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Hongju WuToshiro SekiIgor DmitrievTaco UilElena KashentsevaTie HanDavid T. Curiel. (2002) Double Modification of Adenovirus Fiber with RGD and Polylysine Motifs Improves Coxsackievirus–Adenovirus Receptor-Independent Gene Transfer Efficiency. Human Gene Therapy 13:13, pages 1647-1653.
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Paul J Hippenmeyer, Peter G Ruminski, Joseph G Rico, H.S.Sharon Lu & David W Griggs. (2002) Adenovirus inhibition by peptidomimetic integrin antagonists. Antiviral Research 55:1, pages 169-178.
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Brian P Eliceiri & David A Cheresh. (2001) Adhesion events in angiogenesis. Current Opinion in Cell Biology 13:5, pages 563-568.
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