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Original Research

A randomized, comparative study evaluating the efficacy and tolerability of losartan-low dose chlorthalidone (6.25 mg) combination with losartan-hydrochlorothiazide (12.5 mg) combination in Indian patients with mild-to-moderate essential hypertension

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Pages 1529-1536 | Published online: 11 Jun 2009

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L.E.J. Peeters, M.P. Kester, L. Feyz, P.M.L.A. Van Den Bemt, B.C.P. Koch, T. Van Gelder & J. Versmissen. (2019) Pharmacokinetic and pharmacodynamic considerations in the treatment of the elderly patient with hypertension. Expert Opinion on Drug Metabolism & Toxicology 15:4, pages 287-297.
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Masanori Abe, Kazuyoshi Okada & Koichi Matsumoto. (2009) Clinical experience in treating hypertension with fixed-dose combination therapy: angiotensin II receptor blocker losartan plus hydrochlorothiazide. Expert Opinion on Drug Metabolism & Toxicology 5:10, pages 1285-1303.
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Domenic A Sica. (2009) Chlorthalidone – a renaissance in use?. Expert Opinion on Pharmacotherapy 10:13, pages 2037-2039.
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Articles from other publishers (13)

Eun Joo Cho, Moo Hyun Kim, Young‐Hak Kim, Kiyuk Chang, Dong‐Ju Choi, Woong Chol Kang, Jinho Shin, Seong Hwan Kim, Namho Lee, Jang Won Son, Joon‐Hyung Doh, Woo‐Shik Kim, Soon Jun Hong, Moo‐Yong Rhee, Youngkeun Ahn, Sang‐Wook Lim, Seung Pyo Hong, So‐Yeon Choi, Min Su Hyon, Jin‐Yong Hwang, Kihwan Kwon, Kwang Soo Cha, Sang‐Hyun Ihm, Jae‐Hwan Lee, Byung‐Su Yoo & Hyo‐Soo Kim. (2023) Efficacy and safety of standard dose triple combination of telmisartan 80 mg/amlodipine 5 mg/chlorthalidone 25 mg in primary hypertension: A randomized, double‐blind, active‐controlled, multicenter phase 3 trial. The Journal of Clinical Hypertension 25:9, pages 817-827.
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Raja Ram Khenhrani, Ijeoma Nnodebe, Anurag Rawat, Rahul Adwani, Ammara Ghaffar, Sapna Devi, Muhammad Sohaib Afzal & Muhammad Usama. (2023) Comparison of the Effectiveness and Safety of Chlorthalidone and Hydrochlorothiazide in Patients With Hypertension: A Meta-Analysis. Cureus.
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George C. Roush & Franz H. Messerli. (2021) Chlorthalidone versus hydrochlorothiazide: major cardiovascular events, blood pressure, left ventricular mass, and adverse effects. Journal of Hypertension 39:6, pages 1254-1260.
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Nicholas D. Fried, Tamara M. Morris, Anna Whitehead, Eric Lazartigues, Xinping Yue & Jason D. Gardner. (2021) Angiotensin II type 1 receptor mediates pulmonary hypertension and right ventricular remodeling induced by inhaled nicotine. American Journal of Physiology-Heart and Circulatory Physiology 320:4, pages H1526-H1534.
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Stela Dineva, Katya Uzunova, Velichka Pavlova, Elena Filipova, Krassimir Kalinov & Toni Vekov. (2020) Network meta-analysis of efficacy and safety of chlorthalidone and hydrochlorothiazide in hypertensive patients. Blood Pressure Monitoring 26:2, pages 160-168.
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Anil Pareek, C Venkata S Ram, Ravi T Mehta & Shruti Dharmadhikari. (2020) Optimising TRIUMPH with 6·25 mg chlorthalidone. The Lancet Global Health 8:2, pages e175.
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Stela Dineva, Katya Uzunova, Velichka Pavlova, Elena Filipova, Krassimir Kalinov & Toni Vekov. (2019) Comparative efficacy and safety of chlorthalidone and hydrochlorothiazide—meta-analysis. Journal of Human Hypertension 33:11, pages 766-774.
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Ravi Tejraj Mehta, Anil Pareek & Indranil Purkait. (2018) Chlorthalidone, not hydrochlorothiazide, is the right diuretic for comparison. Clinical Hypertension 24:1.
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Wenjing Liang, Hui Ma, Luxi Cao, Wenjiang Yan & Jingjing Yang. (2017) Comparison of thiazide-like diuretics versus thiazide-type diuretics: a meta-analysis . Journal of Cellular and Molecular Medicine 21:11, pages 2634-2642.
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Anil K. Pareek, Franz H. Messerli, Nitin B. Chandurkar, Shruti K. Dharmadhikari, Anil V. Godbole, Prasita P. Kshirsagar, Manish A. Agarwal, Kamal H. Sharma, Shyam L. Mathur & Mukund M. Kumbla. (2016) Efficacy of Low-Dose Chlorthalidone and Hydrochlorothiazide as Assessed by 24-h Ambulatory Blood Pressure Monitoring. Journal of the American College of Cardiology 67:4, pages 379-389.
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George C. RoushMichael E. ErnstJohn B. KostisSuraj TandonDomenic A. Sica. (2015) Head-to-Head Comparisons of Hydrochlorothiazide With Indapamide and Chlorthalidone. Hypertension 65:5, pages 1041-1046.
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George C. Roush, Michael E. Ernst, John B. Kostis, Ramandeep Kaur & Domenic A. Sica. (2015) Not Just Chlorthalidone: Evidence-Based, Single Tablet, Diuretic Alternatives to Hydrochlorothiazide for Hypertension. Current Hypertension Reports 17:4.
Crossref
Weberton Reis do Carmo, Fabio Furlan Ferreira & Renata Diniz. (2014) Phase quantification of antihypertensive drugs – Chlorthalidone, Hydrochlorothiazide, Losartan and combinations, Losartan/Chlorthalidone and Losartan/Hydrochlorothiazide – by the Rietveld method. Journal of Pharmaceutical and Biomedical Analysis 88, pages 152-156.
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