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Drug Evaluations

The clinical efficacy and abuse potential of combination buprenorphine–naloxone in the treatment of opioid dependence

, BPsych (Hon.) & , BA MBBS MD FRACP FAChAM
Pages 2537-2544 | Published online: 27 Aug 2009

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Morteza Gholami, Ehsan Saboory, Ali Asghar Ahmadi, Mohsen Asouri, Mehrab Nasirikenari & Mostafa Rostamnezhad. (2020) Long-time effects of prenatal morphine, tramadol, methadone, and buprenorphine exposure on seizure and anxiety in immature rats. International Journal of Neuroscience 130:9, pages 898-905.
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Gabi Koller, Andreas Schwarzer, Kathrin Halfter & Michael Soyka. (2019) Pain management in opioid maintenance treatment. Expert Opinion on Pharmacotherapy 20:16, pages 1993-2005.
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Andrea Fanelli, Maria Cristina Sorella & Daniela Ghisi. (2018) Morphine sulfate abuse-deterrent formulations for the treatment of chronic pain. Expert Review of Clinical Pharmacology 11:12, pages 1157-1162.
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Michael Soyka. (2017) Treatment of opioid dependence with buprenorphine: current update. Dialogues in Clinical Neuroscience 19:3, pages 299-308.
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Mellar P. Davis. (2016) Pharmacokinetic and pharmacodynamic evaluation of oxycodone and naltrexone for the treatment of chronic lower back pain. Expert Opinion on Drug Metabolism & Toxicology 12:7, pages 823-831.
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Michael Soyka. (2015) Buprenorphine–naloxone buccal soluble film for the treatment of opioid dependence: current update. Expert Opinion on Drug Delivery 12:2, pages 339-347.
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Robert B Raffa, Robert Taylor$suffix/text()$suffix/text() & Joseph V Pergolizzi$suffix/text()$suffix/text(). (2014) Sequestered naltrexone in sustained release morphine or oxycodone – a way to inhibit illicit use?. Expert Opinion on Drug Safety 13:2, pages 181-190.
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Michael Soyka. (2012) Buprenorphine and buprenorphine/naloxone soluble-film for treatment of opioid dependence. Expert Opinion on Drug Delivery 9:11, pages 1409-1417.
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Sharon Stancliff, Herman Joseph, Chunki Fong, Terry Furst, SandraD. Comer & Perrine Roux. (2012) Opioid Maintenance Treatment as a Harm Reduction Tool for Opioid-Dependent Individuals in New York City: The Need to Expand Access to Buprenorphine/Naloxone in Marginalized Populations. Journal of Addictive Diseases 31:3, pages 278-287.
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Michael Soyka, Henry R. Kranzler, Wim van den Brink, John Krystal, Hans-Jürgen Möller & Siegfried Kasper. (2011) The World Federation of Societies of Biological Psychiatry (WFSBP) Guidelines for the Biological Treatment of Substance Use and Related Disorders. Part 2: Opioid dependence. The World Journal of Biological Psychiatry 12:3, pages 160-187.
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Articles from other publishers (19)

Yatan Pal Singh Balhara, Priyanka Saha, Merlin Mathew, Mukul Kumar, Arpit Parmar, Rakesh Lal & Siddharth Sarkar. (2023) Nonprescription use of buprenorphine tablets among patients at a tertiary care addictive disorder treatment center in India: Observations and implications. Journal of Opioid Management 19:5, pages 403-411.
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Naveen K. Dhagudu, Atul Ambekar, Alok Agrawal, Ravindra Rao, Ashwani K. Mishra, Raka Jain & Shalini Singh. (2020) Is there enough naloxone to deter the diversion? Effect of concurrent administration of intravenous naloxone on opioid agonist effects of intravenous buprenorphine: A randomised, double‐blind, within‐subject, crossover study among opioid‐dependent subjects. Drug and Alcohol Review 39:5, pages 595-603.
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Michael Soyka. 2019. Treatment Resistance in Psychiatry. Treatment Resistance in Psychiatry 179 187 .
Simon Chiu. (2017) Shall we Screen for Cardio-Metabolic Risks in Methadone and Buprenorphine Treatment for Opiate Dependence?. MOJ Addiction Medicine & Therapy 3:1.
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Michael Soyka, Jens Strehle, Jürgen Rehm, Gerhard Bühringer & Hans-Ulrich Wittchen. (2017) Six-Year Outcome of Opioid Maintenance Treatment in Heroin-Dependent Patients: Results from a Naturalistic Study in a Nationally Representative Sample. European Addiction Research 23:2, pages 97-105.
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Jonathan P. Caulkins & Peter Reuter. (2017) Dealing More Effectively and Humanely with Illegal Drugs. Crime and Justice 46:1, pages 95-158.
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Michael Soyka & Jochen Mutschler. (2016) Treatment-refractory substance use disorder: Focus on alcohol, opioids, and cocaine. Progress in Neuro-Psychopharmacology and Biological Psychiatry 70, pages 148-161.
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Essiina Launonen, Hannu Alho, Elina Kotovirta, Isla Wallace & Kaarlo Simojoki. (2015) Diversion of opioid maintenance treatment medications and predictors for diversion among Finnish maintenance treatment patients. International Journal of Drug Policy 26:9, pages 875-882.
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Michael Soyka. (2015) Alcohol Use Disorders in Opioid Maintenance Therapy: Prevalence, Clinical Correlates and Treatment. European Addiction Research 21:2, pages 78-87.
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Michael Soyka, Markus Backmund, Peggy Schmidt & Sabine Apelt. (2014) Buprenorphine-naloxone treatment in opioid dependence and risk of liver enzyme elevation: Results from a 12-month observational study. The American Journal on Addictions 23:6, pages 563-569.
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Theodore J. Cicero, Matthew S. Ellis, Hilary L. Surratt & Steven P. Kurtz. (2014) Factors contributing to the rise of buprenorphine misuse: 2008–2013. Drug and Alcohol Dependence 142, pages 98-104.
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Debasish Basu. (2013) Commentary on Rosenthal et al . (2013): Buprenorphine implant-new hopes, old questions . Addiction 108:12, pages 2150-2151.
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Zachary McCormick, Samuel K. Chu, George C. Chang-Chien & Petra Joseph. (2013) Acute Pain Control Challenges with Buprenorphine/Naloxone Therapy in a Patient with Compartment Syndrome Secondary to McArdle's Disease: A Case Report and Review. Pain Medicine 14:8, pages 1187-1191.
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Michael Soyka. (2013) Buprenorphine Use in Pregnant Opioid Users: A Critical Review. CNS Drugs 27:8, pages 653-662.
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Hanna Uosukainen, Hannu Pentikäinen & Ulrich Tacke. (2013) The effect of an electronic medicine dispenser on diversion of buprenorphine-naloxone—experience from a medium-sized Finnish city. Journal of Substance Abuse Treatment 45:1, pages 143-147.
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Robert B. Raffa, Joseph V. Pergolizzi, Edmundo Muñiz, Robert Taylor & Jason Pergolizzi. (2012) Designing Opioids That Deter Abuse. Pain Research and Treatment 2012, pages 1-10.
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AR Lingford-Hughes, S Welch, L Peters & DJ Nutt. (2012) BAP updated guidelines: evidence-based guidelines for the pharmacological management of substance abuse, harmful use, addiction and comorbidity: recommendations from BAP. Journal of Psychopharmacology 26:7, pages 899-952.
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Briony Larance, Louisa Degenhardt, Nick Lintzeris, James Bell, Adam Winstock, Paul Dietze, Richard Mattick, Robert Ali & Danielle Horyniak. (2011) Post-marketing surveillance of buprenorphine-naloxone in Australia: Diversion, injection and adherence with supervised dosing. Drug and Alcohol Dependence 118:2-3, pages 265-273.
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F.J. Álvarez-González. (2009) Buprenorfina-naloxona: lo nuevo de 2009. Trastornos Adictivos 11:4, pages 247-251.
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