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Expert Opinion on Pharmacotherapy Volume 11, 2010 - Issue 7
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Drug Evaluations

Fingolimod for relapsing multiple sclerosis: an update

Alejandro Horga
, MD,
Joaquín Castilló Multiple Sclerosis Centre of Catalonia (CEM-Cat), Vall d'Hebron University Hospital, Passeig Vall d'Hebron, 119-129, 08035 Barcelona, Spain +34 932746176; +34 932746084; [email protected]
, MD &
Xavier Montalban Multiple Sclerosis Centre of Catalonia (CEM-Cat), Vall d'Hebron University Hospital, Passeig Vall d'Hebron, 119-129, 08035 Barcelona, Spain +34 932746176; +34 932746084; [email protected]
, MD PhD
Pages 1183-1196 | Published online: 05 Apr 2010

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Katja Thomas, Undine Proschmann & Tjalf Ziemssen. (2017) Fingolimod hydrochloride for the treatment of relapsing remitting multiple sclerosis. Expert Opinion on Pharmacotherapy 18:15, pages 1649-1660.
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Jong-Mi Lee & May H Han. (2015) Patient experience and practice trends in multiple sclerosis – clinical utility of fingolimod. Patient Preference and Adherence 9, pages 685-693.
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Articles from other publishers (16)

Nora Möhn, Refik Pul, Christoph Kleinschnitz, Harald Prüss, Torsten Witte, Martin Stangel & Thomas Skripuletz. (2020) Implications of COVID-19 Outbreak on Immune Therapies in Multiple Sclerosis Patients—Lessons Learned From SARS and MERS. Frontiers in Immunology 11.
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Tomasz Grzegorski & Jacek Losy. (2019) Multiple sclerosis – the remarkable story of a baffling disease. Reviews in the Neurosciences 30:5, pages 511-526.
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Nelleke Snelder, Bart A. Ploeger, Olivier Luttringer, Dean F. Rigel, Randy L. Webb, David Feldman, Fumin Fu, Michael Beil, Liang Jin, Donald R. Stanski & Meindert Danhof. (2017) Characterization and Prediction of Cardiovascular Effects of Fingolimod and Siponimod Using a Systems Pharmacology Modeling Approach. Journal of Pharmacology and Experimental Therapeutics 360:2, pages 356-367.
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Matthias Hoch, Borje Darpo, Patrick Brossard, Meijian Zhou, Randall Stoltz & Jasper Dingemanse. (2015) Effect of Ponesimod, a Selective S1P 1 Receptor Modulator, on the QT Interval in Healthy Individuals . Basic & Clinical Pharmacology & Toxicology 116:5, pages 429-437.
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M. Hoch, D. D’Ambrosio, D. Wilbraham, P. Brossard & J. Dingemanse. (2014) Clinical pharmacology of ponesimod, a selective S1P1 receptor modulator, after uptitration to supratherapeutic doses in healthy subjects. European Journal of Pharmaceutical Sciences 63, pages 147-153.
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Nicki Ward-Abel, Karen Vernon & Richard Warner. (2014) An exciting era of treatments for relapsing-remitting multiple sclerosis. British Journal of Neuroscience Nursing 10:1, pages 21-28.
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P. Brossard, M. Scherz, A. Halabi, H. Maatouk, A. Krause & J. Dingemanse. (2014) Multiple-dose tolerability, pharmacokinetics, and pharmacodynamics of ponesimod, an S1P 1 receptor modulator: Favorable impact of dose up-titration . The Journal of Clinical Pharmacology 54:2, pages 179-188.
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Katja Thomas & Tjalf Ziemssen. (2013) Management of fingolimod in clinical practice. Clinical Neurology and Neurosurgery 115, pages S60-S64.
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Hidetaka Sakurai, Kazuishi Kubota, Shin-ichi Inaba, Kaoru Takanaka & Akira Shinagawa. (2013) Identification of a Metabolizing Enzyme in Human Kidney by Proteomic Correlation Profiling. Molecular & Cellular Proteomics 12:8, pages 2313-2323.
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Daniel Ontaneda, Claire Hara-Cleaver, Richard A. Rudick, Jeffrey A. Cohen & Robert A. Bermel. (2012) Early tolerability and safety of fingolimod in clinical practice. Journal of the Neurological Sciences 323:1-2, pages 167-172.
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Carola T. Murphy, Lindsay J. Hall, Grainne Hurley, Aoife Quinlan, John MacSharry, Fergus Shanahan, Kenneth Nally & Silvia Melgar. (2012) The Sphingosine-1-Phosphate Analogue FTY720 Impairs Mucosal Immunity and Clearance of the Enteric Pathogen Citrobacter rodentium. Infection and Immunity 80:8, pages 2712-2723.
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Ahmed H. Badawi & Teruna J. Siahaan. (2012) Immune modulating peptides for the treatment and suppression of multiple sclerosis. Clinical Immunology 144:2, pages 127-138.
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Kiyoaki Yonesu, Kazuishi Kubota, Masakazu Tamura, Shin-ichi Inaba, Tomohiro Honda, Chizuko Yahara, Nobuaki Watanabe, Tatsuji Matsuoka & Futoshi Nara. (2011) Purification and Identification of Activating Enzymes of CS-0777, a Selective Sphingosine 1-Phosphate Receptor 1 Modulator, in Erythrocytes. Journal of Biological Chemistry 286:28, pages 24765-24775.
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Stephen Krieger. (2011) Multiple Sclerosis Therapeutic Pipeline: Opportunities and Challenges. Mount Sinai Journal of Medicine: A Journal of Translational and Personalized Medicine 78:2, pages 192-206.
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Joy Derwenskus. (2011) Current Disease‐Modifying Treatment of Multiple Sclerosis. Mount Sinai Journal of Medicine: A Journal of Translational and Personalized Medicine 78:2, pages 161-175.
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Jennifer M. Belavic. (2011) Annual Drug Update. The Nurse Practitioner 36:2, pages 10-22.
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