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Treating skin cancer with topical cream

, MD, , MD, , MD, , MD & , MD PhD
Pages 1515-1527 | Published online: 21 Apr 2010

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Read on this site (7)

Kristen Russomanno, Sara Abdel Azim & Vishal A Patel. (2023) Immunomodulators for Non-Melanoma Skin Cancers: Updated Perspectives. Clinical, Cosmetic and Investigational Dermatology 16, pages 1025-1045.
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Marina Agozzino, Teresa Russo, Chiara Franceschini, Sara Mazzilli, Virginia Garofalo, Elena Campione, Luca Bianchi, Massimo Milani & Giuseppe Argenziano. (2019) Effects of topical piroxicam and sun filters in actinic keratosis evolution and field cancerization: a two-center, assessor-blinded, clinical, confocal microscopy and dermoscopy evaluation trial. Current Medical Research and Opinion 35:10, pages 1785-1792.
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Mario Puviani, Chiara Galloni, Silvia Marchetti, Paolo Sergio Pavone, Silvia Lovati, Giuseppe Pistone, Valentina Caputo, Giovanna Tilotta, Giuseppe Scarcella, Elena Campione, Laura Diluvio, Virginia Garofalo, Luca Bianchi & Massimo Milani. (2017) Efficacy of a film-forming medical device containing sunscreen (50+) and piroxicam 0.8% in actinic keratosis and field cancerization: a multicenter, assessor-blinded, 3 month trial. Current Medical Research and Opinion 33:7, pages 1255-1259.
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Giuseppe Micali, Francesco Lacarrubba, Karishma Bhatt & Maria Rita Nasca. (2013) Medical approaches to non-melanoma skin cancer. Expert Review of Anticancer Therapy 13:12, pages 1409-1421.
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Marco Bragagni, Natascia Mennini, Francesca Maestrelli, Marzia Cirri & Paola Mura. (2012) Comparative study of liposomes, transfersomes and ethosomes as carriers for improving topical delivery of celecoxib. Drug Delivery 19:7, pages 354-361.
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Francesco Lacarrubba, Maria Concetta Potenza, Silvia Gurgone & Giuseppe Micali. (2011) Successful treatment and management of large superficial basal cell carcinomas with topical imiquimod 5% cream: A case series and review. Journal of Dermatological Treatment 22:6, pages 353-358.
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Sven R Quist & Harald P Gollnick. (2011) Imiquimod 3.75% cream (Zyclara) for the treatment of actinic keratoses. Expert Opinion on Pharmacotherapy 12:3, pages 451-461.
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Articles from other publishers (33)

Emilio Garcia-Mouronte, Emilio Berna-Rico, Belen de Nicolas-Ruanes, Carlos Azcarraga-Llobet, Luis Alonso-Martinez de Salinas & Sonia Bea-Ardebol. (2023) Imiquimod as Local Immunotherapy in the Management of Premalignant Cutaneous Conditions and Skin Cancer. International Journal of Molecular Sciences 24:13, pages 10835.
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Nabila A. El-Sheridy, Riham M. El-Moslemany, Alyaa A. Ramadan, Maged W. Helmy & Labiba K. El-Khordagui. (2022) Itraconazole for Topical Treatment of Skin Carcinogenesis: Efficacy Enhancement by Lipid Nanocapsule Formulations. Journal of Biomedical Nanotechnology 18:1, pages 97-111.
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Sanjoy Das, Sentu Das & Malay K. Das. 2022. Nanocosmeceuticals. Nanocosmeceuticals 31 69 .
Piyush Kumar, Sanjay Khare, Santoshdev P. Rathod, Esther Nimisha, Meenaz Khoja, Sandeep Kulkarni, Anup Kumar Tiwary & Bhushan Madke. 2022. Atlas of Dermatology, Dermatopathology and Venereology. Atlas of Dermatology, Dermatopathology and Venereology 911 990 .
Torsten Bohn, M. Luisa Bonet, Patrick Borel, Jaap Keijer, Jean-Francois Landrier, Irina Milisav, Joan Ribot, Patrizia Riso, Brigitte Winklhofer-Roob, Yoav Sharoni, Joana Corte-Real, Yvonne van Helden, Monica Rosa Loizzo, Borut Poljšak, Marisa Porrini, Johannes Roob, Polonca Trebše, Rosa Tundis, Agata Wawrzyniak, Ralph Rühl & Joanna Dulińska-Litewka. (2021) Mechanistic aspects of carotenoid health benefits – where are we now?. Nutrition Research Reviews 34:2, pages 276-302.
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Anna Elisa Verzì, Giuseppe Micali & Francesco Lacarrubba. (2021) Line-Field Confocal Optical Coherence Tomography May Enhance Monitoring of Superficial Basal Cell Carcinoma Treated with Imiquimod 5% Cream: A Pilot Study. Cancers 13:19, pages 4913.
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Juho Lee, Shwe Phyu Hlaing, Nurhasni Hasan, Dongmin Kwak, Hyunwoo Kim, Jiafu Cao, In-Soo Yoon, Hwayoung Yun, Yunjin Jung & Jin-Wook Yoo. (2021) Tumor-Penetrable Nitric Oxide-Releasing Nanoparticles Potentiate Local Antimelanoma Therapy. ACS Applied Materials & Interfaces 13:26, pages 30383-30396.
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Anna Paula Azevedo de Carvalho & Carlos Adam Conte-Junior. (2021) Health benefits of phytochemicals from Brazilian native foods and plants: Antioxidant, antimicrobial, anti-cancer, and risk factors of metabolic/endocrine disorders control. Trends in Food Science & Technology 111, pages 534-548.
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Mohammed S. Algahtani, Mohammad Zaki Ahmad, Ihab Hamed Nourein & Javed Ahmad. (2020) Co-Delivery of Imiquimod and Curcumin by Nanoemugel for Improved Topical Delivery and Reduced Psoriasis-Like Skin Lesions. Biomolecules 10:7, pages 968.
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Yong Hao, Bin Peng, Delu Che, Yi Zheng, Shuzhen Kong, Rui Liu, Jihai Shi, Hui Han, Jue Wang, Jiao Cao, Yongjing Zhang, Jiapan Gao, Langchong He & Songmei Geng. (2020) Imiquimod-related dermatitis is mainly mediated by mast cell degranulation via Mas-related G-protein coupled receptor B2. International Immunopharmacology 81, pages 106258.
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Livia Neves Borgheti-Cardoso, Juliana Santos Rosa Viegas, Ana Vitoria Pupo Silvestrini, Angelo Luis Caron, Fabiola Garcia Praça, Marcelo Kravicz & Maria Vitória Lopes Badra Bentley. (2020) Nanotechnology approaches in the current therapy of skin cancer. Advanced Drug Delivery Reviews 153, pages 109-136.
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Piyush Kumar, Sanjay Khare, Santoshdev P. Rathod, Esther Nimisha, Meenaz Khoja, Sandeep Kulkarni, Anup Kumar Tiwary & Bhushan Madke. 2019. Atlas of Dermatology, Dermatopathology and Venereology. Atlas of Dermatology, Dermatopathology and Venereology 1 80 .
Maha El-Kayal, Maha Nasr, Seham Elkheshen & Nahed Mortada. (2019) Colloidal (-)-epigallocatechin-3-gallate vesicular systems for prevention and treatment of skin cancer: A comprehensive experimental study with preclinical investigation. European Journal of Pharmaceutical Sciences 137, pages 104972.
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Kristyn Deen & David Burdon‐Jones. (2016) Imiquimod in the treatment of penile intraepithelial neoplasia: An update. Australasian Journal of Dermatology 58:2, pages 86-92.
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Swarnendra Singh, Atif Zafar, Saman Khan & Imrana Naseem. (2017) Towards therapeutic advances in melanoma management: An overview. Life Sciences 174, pages 50-58.
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Mikael Larsson, Wei-Ting Huang, Dean-Mo Liu & Dusan Losic. (2017) Local co-administration of gene-silencing RNA and drugs in cancer therapy: State-of-the art and therapeutic potential. Cancer Treatment Reviews 55, pages 128-135.
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Elena Campione, Monia Di Prete, Ilaria Del Principe, Laura Diluvio, Luigi Citarella, Augusto Orlandi, Sergio Chimenti & Luca Bianchi. (2016) Lack of efficacy of imiquimod in patients with basal cell carcinoma previously treated with rituximab for B cell lymphoma: two case reports. Journal of Medical Case Reports 10:1.
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Eric L. Maranda, Austin H. Nguyen, Victoria M. Lim, Vidhi V. Shah & Joaquin J. Jimenez. (2016) Erythroplasia of Queyrat treated by laser and light modalities: a systematic review. Lasers in Medical Science 31:9, pages 1971-1976.
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Takuma Shibata, Umeharu Ohto, Shosaku Nomura, Kayoko Kibata, Yuji Motoi, Yan Zhang, Yusuke Murakami, Ryutaro Fukui, Tatsushi Ishimoto, Shigetoshi Sano, Tomoki Ito, Toshiyuki Shimizu & Kensuke Miyake. (2016) Guanosine and its modified derivatives are endogenous ligands for TLR7. International Immunology 28:5, pages 211-222.
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Cristina G. Venturini, Franciele A. Bruinsmann, Renata V. Contri, Francisco N. Fonseca, Luiza A. Frank, Camilo M. D’Amore, Renata P. Raffin, Andréia Buffon, Adriana R. Pohlmann & Silvia S. Guterres. (2015) Co-encapsulation of imiquimod and copaiba oil in novel nanostructured systems: promising formulations against skin carcinoma. European Journal of Pharmaceutical Sciences 79, pages 36-43.
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Giuseppe Micali, Francesco Lacarrubba, Maria Rita Nasca & Robert A. Schwartz. (2014) Topical pharmacotherapy for skin cancer. Journal of the American Academy of Dermatology 70:6, pages 965.e1-965.e12.
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Giuseppe Micali, Francesco Lacarrubba, Maria Rita Nasca, Salvatore Ferraro & Robert A. Schwartz. (2014) Topical pharmacotherapy for skin cancer. Journal of the American Academy of Dermatology 70:6, pages 979.e1-979.e12.
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Fiona Bath-Hextall, Mara Ozolins, Sarah J Armstrong, Graham B Colver, William Perkins, Paul S J Miller & Hywel C Williams. (2014) Surgical excision versus imiquimod 5% cream for nodular and superficial basal-cell carcinoma (SINS): a multicentre, non-inferiority, randomised controlled trial. The Lancet Oncology 15:1, pages 96-105.
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Patricia L. Myskowski. 2013. Dermatologic Principles and Practice in Oncology. Dermatologic Principles and Practice in Oncology 301 309 .
Elizabeth A. Quigley & Allan C. Halpern. (2013) Microinvasive Melanoma. American Journal of Clinical Dermatology 14:2, pages 125-137.
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Giuseppe Micali, Marco Cusini, Pompeo Donofrio & Franco DinottaGiuseppe Micali, Francesco Lacarrubba, Philip J. Cohen & Robert A. Schwartz. 2013. Atlas of Male Genital Disorders. Atlas of Male Genital Disorders 127 151 .
Puiyan Lee, Adnan Nasir & Kenneth K. Y. Wong. 2013. Nanotechnology in Dermatology. Nanotechnology in Dermatology 119 125 .
Husein Husein-ElAhmed. (2012) Multiple Basal Cell Carcinomas Arising in a Surgical Scar After Radiotherapy. Annals of the Academy of Medicine, Singapore 41:11, pages 536-537.
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Steven M. Couch & Philip L. Custer. (2012) Topical 5-Fluorouracil for the Treatment of Periocular Actinic Keratosis and Low-Grade Squamous Malignancy. Ophthalmic Plastic & Reconstructive Surgery 28:3, pages 181-183.
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Elisabeth M.T. Wurm, Claudia E.S. Curchin, Duncan Lambie, Caterina Longo, Giovanni Pellacani & H. Peter Soyer. (2012) Confocal features of equivocal facial lesions on severely sun-damaged skin: Four case studies with dermatoscopic, confocal, and histopathologic correlation. Journal of the American Academy of Dermatology 66:3, pages 463-473.
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S. Rangwala & K.Y. Tsai. (2011) Roles of the immune system in skin cancer. British Journal of Dermatology 165:5, pages 953-965.
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A.T. Ermertcan, F. Öztürk & K. Gündüz. (2011) Toll-like receptors and skin. Journal of the European Academy of Dermatology and Venereology 25:9, pages 997-1006.
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J Wood, M Pring, J W Eveson, N Price, C M Proby & A Hague. (2011) Co-overexpression of Bag-1 and heat shock protein 70 in human epidermal squamous cell carcinoma: Bag-1-mediated resistance to 5-fluorouracil-induced apoptosis. British Journal of Cancer 104:9, pages 1459-1471.
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