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Drug Evaluations

Lacosamide: new adjunctive treatment option for partial-onset seizures

, MD
Pages 1595-1602 | Published online: 19 May 2010

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Srđan Stefanović, Slobodan M. Janković, Milan Novaković, Marko Milosavljević & Marko Folić. (2018) Pharmacodynamics and common drug-drug interactions of the third-generation antiepileptic drugs. Expert Opinion on Drug Metabolism & Toxicology 14:2, pages 153-159.
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Zhixiao Wang, Xuan Li, Annette Powers & Jose E Cavazos. (2015) Outcomes associated with switching from monotherapy to adjunctive therapy for patients with partial onset seizures. Expert Review of Pharmacoeconomics & Outcomes Research 15:2, pages 349-355.
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Articles from other publishers (25)

Shantilal Padhiyar, Kamlesh M Jivani, Jagat Upadhyay, Tejas Patel & Bhanubhai Suhagia. (2022) Development and Validation of Stability-Indicating High-Performance Liquid Chromatography Method for Estimation of Lacosamide in Bulk and Its Pharmaceutical Dosage Form. Journal of Chromatographic Science.
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Bruna Nucera, Francesco Brigo, Eugen Trinka & Gudrun Kalss. (2022) Treatment and care of women with epilepsy before, during, and after pregnancy: a practical guide. Therapeutic Advances in Neurological Disorders 15, pages 175628642211016.
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Eugen Trinka, Wan Tsong, Sydney Toupin, Anna Patten, Katy Wilson, Jaana Isojarvi & Daniel James. (2020) A systematic review and indirect treatment comparison of perampanel versus brivaracetam as adjunctive therapy in patients with focal-onset seizures with or without secondary generalization. Epilepsy Research 166, pages 106403.
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Patrick M. Wieruszewski, Arnaldo Lopez-Ruiz, Robert C. Albright, Jennifer E. Fugate & Erin Frazee Barreto. (2018) Lacosamide Pharmacokinetics in a Critically Ill Patient During Continuous Renal Replacement Therapy. Journal of Pharmacy Practice 33:3, pages 395-398.
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Li-na Zhu, Deng Chen, Ge Tan, Hai-jiao Wang, Shanshan Chu & Ling Liu. (2020) The tolerability and safety profile of eslicarbazepine acetate in neurological disorders. Journal of the Neurological Sciences 413, pages 116772.
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Jesse Fishman, Melinda Martin, David M. Labiner, Carolyn R. Lew & Barbara H. Johnson. (2019) Healthcare resource utilization and costs before and after lacosamide initiation as adjunctive therapy among patients with epilepsy in the United States. Epilepsy & Behavior 99, pages 106331.
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Ilker Gunyeli, Mustafa Saygin & Ozlem Ozmen. (2019) Overall systematic approach to sepsis damages on urogenital tissues: protective power of lacosamide. Archives of Gynecology and Obstetrics 300:4, pages 941-955.
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Isabelle Beuchat, Jan Novy & Andrea O. Rossetti. (2018) Newer Antiepileptic Drugs for Status Epilepticus in Adults: What’s the Evidence?. CNS Drugs 32:3, pages 259-267.
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Shery Jacob & Anroop B. Nair. (2016) An Updated Overview on Therapeutic Drug Monitoring of Recent Antiepileptic Drugs. Drugs in R&D 16:4, pages 303-316.
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Deng Chen, Yan Lin, Tao Chen, Qin Zhang, Yan Lin, Yang Si, Wen-wu Zhang, Da Xu & Ling Liu. (2016) Dose effects of lacosamide as add-on therapy for partial-onset seizure in adult. Neurological Sciences 37:6, pages 907-920.
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Vanessa Paquette, Celia Culley, Erica D. Greanya & Mary H.H. Ensom. (2015) Lacosamide as adjunctive therapy in refractory epilepsy in adults: A systematic review. Seizure 25, pages 1-17.
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Sofia Markoula, Rute Teotonio, Neville Ratnaraj, John S. Duncan, Josemir W. Sander & Philip N. Patsalos. (2014) Lacosamide Serum Concentrations in Adult Patients With Epilepsy. Therapeutic Drug Monitoring 36:4, pages 494-498.
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Marlon G. Saria, Courtney Corle, Jethro HuJeremy D. RudnickSurasak PhuphanichMaciej M. MrugalaLaura K. CrewDaniela A. BotaBeverly Dan Fu, Ryan Y. Kim, Tiffany Brown, Homira FeelyJoanne Brechlin, Bradley D. Brown, Jan Drappatz, Patrick Y. Wen, Clark C. ChenBob CarterJong Woo Lee & Santosh Kesari. (2013) Retrospective analysis of the tolerability and activity of lacosamide in patients with brain tumors. Journal of Neurosurgery 118:6, pages 1183-1187.
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Gaetano Zaccara, Piero Perucca, Giulia Loiacono, Fabio Giovannelli & Alberto Verrotti. (2012) The adverse event profile of lacosamide: A systematic review and meta‐analysis of randomized controlled trials. Epilepsia 54:1, pages 66-74.
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Dimitrios Chatzistefanidis, Eleni Karvouni, Athanassios P. Kyritsis & Sofia Markoula. (2013) First Case of Lacosamide-Induced Psychosis. Clinical Neuropharmacology 36:1, pages 27-28.
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Carlos Casas-Fernández, Antonio Martínez-Bermejo, Miguel Rufo-Campos, Patricia Smeyers-Durá, José L. Herranz-Fernández, Salvador Ibáñez-Micó, Jaume Campistol-Plana, Helena Alarcón-Martínez & Jaime Campos-Castelló. (2012) Efficacy and Tolerability of Lacosamide in the Concomitant Treatment of 130 Patients Under 16 Years of Age with Refractory Epilepsy. Drugs in R&D 12:4, pages 187-197.
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James W. Wheless. 2012. Epilepsy in Children and Adolescents. Epilepsy in Children and Adolescents 175 192 .
H. B. Edwards, A. G. Cole, A. S. Griffiths, B. Lin, A. Bean & G. L. Krauss. (2012) Minimizing pharmacodynamic interactions of high doses of lacosamide. Acta Neurologica Scandinavica 125:4, pages 228-233.
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L. Mnatsakanyan, J.M. Chung, E.I. Tsimerinov & D.S. Eliashiv. (2012) Intravenous Lacosamide in refractory nonconvulsive status epilepticus. Seizure 21:3, pages 198-201.
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Danièle Bentué-Ferrer, Olivier Tribut & Marie-Clémence Verdier. (2012) Suivi thérapeutique pharmacologique du lacosamide. Therapies 67:2, pages 151-155.
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Volker Briese. 2011. Arzneimittel und Nahrungsergänzungsmittel in Schwangerschaft und Stillzeit. Arzneimittel und Nahrungsergänzungsmittel in Schwangerschaft und Stillzeit 55 58 .
Laura M.F.F. Guilhoto, Tobias Loddenkemper, Vasu D. Gooty, Alexander Rotenberg, Masanori Takeoka, Frank H. Duffy, David Coulter, David Urion, Blaise F. Bourgeois & Sanjeev V. Kothare. (2011) Experience With Lacosamide in a Series of Children With Drug-Resistant Focal Epilepsy. Pediatric Neurology 44:6, pages 414-419.
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Paolo Prunetti & Emilio Perucca. (2011) New and forthcoming anti-epileptic drugs. Current Opinion in Neurology 24:2, pages 159-164.
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Steve Chung, Elinor Ben-Menachem, Michael R. Sperling, William Rosenfeld, Nathan B. Fountain, Selim Benbadis, David Hebert, Jouko Isojärvi & Pamela Doty. (2010) Examining the Clinical Utility of Lacosamide. CNS Drugs 24:12, pages 1041-1054.
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