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Drug Evaluations

Pixantrone for the treatment of aggressive non-Hodgkin lymphoma

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Pages 1915-1923 | Published online: 23 Jun 2010

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Sandy Amorim, Isabelle Fleury, Nicolas Mounier, Stéphanie Harel, Pauline Brice & Catherine Thieblemont. (2016) Consolidation therapy with mitoxantrone, ifosfamide and etoposide with or without rituximab before stem cell transplantation in relapsed diffuse large B-cell lymphoma patients failing second-line treatment. Leukemia & Lymphoma 57:10, pages 2425-2428.
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Mariam Jamal-Hanjani & Ruth Pettengell. (2011) Pharmacokinetic evaluation of pixantrone for the treatment of non-Hodgkin's lymphoma. Expert Opinion on Drug Metabolism & Toxicology 7:11, pages 1441-1448.
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Manmeet Kaur, Mandeep Kaur, Tania Bandopadhyay, Aditi Sharma, Anu Priya, Arvind Singh & Bubun Banerjee. (2023) Naturally occurring, natural product inspired and synthetic heterocyclic anti-cancer drugs. Physical Sciences Reviews 8:10, pages 3393-3446.
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Francesco Malaspina, Cinzia Pellegrini, Beatrice Casadei, Lisa Argnani & Pier Luigi Zinzani. (2017) Impressive Response to Pixantrone after Allogeneic Transplant in a Multiple Relapsed Diffuse Large B-Cell Lymphoma. Acta Haematologica 137:4, pages 191-194.
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Pier Luigi Zinzani, Paolo Corradini, Maurizio Martelli, Giorgio Minotti, Stefano Oliva, Michele Spina, Giovanni Barosi & Sante Tura. (2016) Critical concepts, practice recommendations, and research perspectives of pixantrone therapy in non-Hodgkin lymphoma: a SIE, SIES, and GITMO consensus paper. European Journal of Haematology 97:6, pages 554-561.
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B. B. Hasinoff, X. Wu, D. Patel, R. Kanagasabai, S. Karmahapatra & J. C. Yalowich. (2015) Mechanisms of Action and Reduced Cardiotoxicity of Pixantrone; a Topoisomerase II Targeting Agent with Cellular Selectivity for the Topoisomerase II  Isoform. Journal of Pharmacology and Experimental Therapeutics 356:2, pages 397-409.
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Hong X. Ding, Carolyn A. Leverett, Robert E. KyneJr.Jr., Kevin K.-C. Liu, Subas M. Sakya, Andrew C. Flick & Christopher J. O’Donnell. (2014) Synthetic approaches to the 2012 new drugs. Bioorganic & Medicinal Chemistry 22:7, pages 2005-2032.
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Ruth Pettengell, Bertrand Coiffier, Geetha Narayanan, Fernando Hurtado de Mendoza, Raghunadharao Digumarti, Henry Gomez, Pier Luigi Zinzani, Gary Schiller, David Rizzieri, Giles Boland, Paul Cernohous, Lixia Wang, Christine Kuepfer, Igor Gorbatchevsky & Jack W Singer. (2012) Pixantrone dimaleate versus other chemotherapeutic agents as a single-agent salvage treatment in patients with relapsed or refractory aggressive non-Hodgkin lymphoma: a phase 3, multicentre, open-label, randomised trial. The Lancet Oncology 13:7, pages 696-706.
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Paul A. Fields & David C. Linch. (2012) Treatment of the elderly patient with diffuse large B cell lymphoma. British Journal of Haematology 157:2, pages 159-170.
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Benny J. Evison, Mile Pastuovic, Rebecca A. Bilardi, Robert A. Forrest, Paul P. Pumuye, Brad E. Sleebs, Keith G. Watson, Don R. Phillips & Suzanne M. Cutts. (2011) M2, a novel anthracenedione, elicits a potent DNA damage response that can be subverted through checkpoint kinase inhibition to generate mitotic catastrophe. Biochemical Pharmacology 82:11, pages 1604-1618.
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