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Long-acting injectable antipsychotics in the treatment of schizophrenia: their role in relapse prevention

, MD, , MD MSc FRCPC & , MD PhD FRCPC
Pages 2301-2317 | Published online: 30 Jun 2010

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Mikkel Højlund & Christoph U. Correll. (2023) Switching to long-acting injectable antipsychotics: pharmacological considerations and practical approaches. Expert Opinion on Pharmacotherapy 24:13, pages 1463-1489.
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Renato de Filippis, Pasquale De Fazio, Raffaele Gaetano, Luca Steardo, Clemente Cedro, Antonio Bruno, Rocco Antonio Zoccali & Maria Rosaria Anna Muscatello. (2021) Current and emerging long-acting antipsychotics for the treatment of schizophrenia. Expert Opinion on Drug Safety 20:7, pages 771-790.
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Clifton Blackwood, Panna Sanga, Isaac Nuamah, Alexander Keenan, Arun Singh, Maju Mathews & Srihari Gopal. (2020) Patients’ Preference for Long-Acting Injectable versus Oral Antipsychotics in Schizophrenia: Results from the Patient-Reported Medication Preference Questionnaire. Patient Preference and Adherence 14, pages 1093-1102.
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Tianmei Si, Jianmin Zhuo, Yu Feng, Huafei Lu, Di Hong & Lili Zhang. (2019) Long-term efficacy and safety of paliperidone palmitate once-monthly in Chinese patients with recent-onset schizophrenia. Neuropsychiatric Disease and Treatment 15, pages 1685-1694.
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Dominic Pilon, Tony B. Amos, Rhiannon Kamstra, Ameur M. Manceur, Antoine C. El Khoury & Patrick Lefebvre. (2019) Short-term rehospitalizations in young adults with schizophrenia treated with once-monthly paliperidone palmitate or oral atypical antipsychotics: a retrospective analysis. Current Medical Research and Opinion 35:1, pages 41-49.
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David M. Taylor, Sitaram Velaga & Ursula Werneke. (2018) Reducing the stigma of long acting injectable antipsychotics – current concepts and future developments. Nordic Journal of Psychiatry 72:sup1, pages S36-S39.
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Jingping Zhao, Lehua Li, Jianguo Shi, Yi Li, Xiufeng Xu, Keqing Li, Lili Zhang, Shangli Cai, Yu Feng, Jianmin Zhuo, Weihong Liu & Huafei Lu. (2017) Safety and efficacy of paliperidone palmitate 1-month formulation in Chinese patients with schizophrenia: a 25-week, open-label, multicenter, Phase IV study. Neuropsychiatric Disease and Treatment 13, pages 2045-2056.
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Andrea de Bartolomeis, Andrea Fagiolini, Marco Vaggi & Claudio Vampini. (2016) Targets, attitudes, and goals of psychiatrists treating patients with schizophrenia: key outcome drivers, role of quality of life, and place of long-acting antipsychotics. Neuropsychiatric Disease and Treatment 12, pages 99-108.
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L. Orsolini, C. Tomasetti, A. Valchera, R. Vecchiotti, I. Matarazzo, F. Vellante, F. Iasevoli, E. F. Buonaguro, M. Fornaro, A. L. C. Fiengo, G. Martinotti, M. Mazza, G. Perna, A. Carano, A. De Bartolomeis, M. Di Giannantonio & D. De Berardis. (2016) An update of safety of clinically used atypical antipsychotics. Expert Opinion on Drug Safety 15:10, pages 1329-1347.
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Fan Zhang, Tianmei Si, Chiun-Fang Chiou, Anthony WF Harris, Chang Yoon Kim, Padmashree Jahagirdar & Steve Ascher. (2015) Efficacy, safety, and impact on hospitalizations of paliperidone palmitate in recent-onset schizophrenia. Neuropsychiatric Disease and Treatment 11, pages 657-668.
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Nesrin Dilbaz. (2015) New Targets for the Management of Schizophrenia. Klinik Psikofarmakoloji Bülteni-Bulletin of Clinical Psychopharmacology 25:4, pages 407-428.
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Srihari Gopal, An Vermeulen, Partha Nandy, Paulien Ravenstijn, Isaac Nuamah, José Antonio Buron Vidal, Joris Berwaerts, Adam Savitz, David Hough & Mahesh N. Samtani. (2015) Practical guidance for dosing and switching from paliperidone palmitate 1 monthly to 3 monthly formulation in schizophrenia. Current Medical Research and Opinion 31:11, pages 2043-2054.
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Luis San, Manuel Serrano, Fernando Cañas, Samuel Leopoldo Romero, Ángeles Sánchez-Cabezudo & Mariano Villar. (2015) Towards a pragmatic and operational definition of relapse in schizophrenia: A Delphi consensus approach. International Journal of Psychiatry in Clinical Practice 19:2, pages 90-98.
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Stefania Ruiu, Maria Antonietta Casu, Gianluca Casu, Sara Piras & Giorgio Marchese. (2012) Effects of controlled-release formulations of atypical antipsychotics on functioning and quality of life of schizophrenic individuals. Expert Opinion on Pharmacotherapy 13:11, pages 1631-1643.
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