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Recent advances in antiretroviral drugs

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Pages 31-46 | Published online: 10 Aug 2010

Keep up to date with the latest research on this topic with citation updates for this article.

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Jacqueline Sagen & Aldric T Hama. (2016) Antinociceptive effects of topical mepivacaine in a rat model of HIV-associated peripheral neuropathic pain. Journal of Pain Research 9, pages 361-371.
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Narasimha M. Midde, Benjamin J. Patters, PSS Rao, Theodore J. Cory & Santosh Kumar. (2016) Investigational protease inhibitors as antiretroviral therapies. Expert Opinion on Investigational Drugs 25:10, pages 1189-1200.
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Boshi Huang, Dongwei Kang, Peng Zhan & Xinyong Liu. (2015) Fragment-based approaches to anti-HIV drug discovery: state of the art and future opportunities. Expert Opinion on Drug Discovery 10:12, pages 1271-1281.
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Steven E Lipshultz, Catherine M Mas, Jacqueline M Henkel, Vivian I Franco, Stacy D Fisher & Tracie L Miller. (2012) HAART to heart: highly active antiretroviral therapy and the risk of cardiovascular disease in HIV-infected or exposed children and adults. Expert Review of Anti-infective Therapy 10:6, pages 661-674.
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Nathan Ford & Alexandra Calmy. (2012) Expert reviews: who are they for?. Expert Opinion on Pharmacotherapy 13:8, pages 1083-1085.
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Sarah Hanley, Jonathan Brown, Peter Timmins, Catrin Davies & Andrew Dennis. (2022) Unexpected Stability of a Prodrug to Enzymatic Hydrolysis within a Hydrated HPMC Matrix Tablet. Pharmaceutics 14:10, pages 2222.
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Ashwini Amol Sawant, Surender Singh Jadav, Kiranmai Nayani & Prathama S. Mainkar. (2022) Development of Synthetic Approaches Towards HIV Integrase Strand Transfer Inhibitors (INSTIs). ChemistrySelect 7:29.
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Yasemin van Heuvel, Stefanie Schatz, Jamila Franca Rosengarten & Jörn Stitz. (2022) Infectious RNA: Human Immunodeficiency Virus (HIV) Biology, Therapeutic Intervention, and the Quest for a Vaccine. Toxins 14:2, pages 138.
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Sofi Imtiyaz Ali, Wajid Mohammad Sheikh, Muzafar Ahmad Rather, Venugopalan Venkatesalu, Showkeen Muzamil Bashir & Showkat Ul Nabi. (2021) Medicinal plants: Treasure for antiviral drug discovery. Phytotherapy Research 35:7, pages 3447-3483.
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Mayumi Takahashi, Haitang Li, Jiehua Zhou, Pritsana Chomchan, Veenu Aishwarya, Masad J. Damha & John J. Rossi. (2019) Dual Mechanisms of Action of Self-Delivering, Anti-HIV-1 FANA Oligonucleotides as a Potential New Approach to HIV Therapy. Molecular Therapy - Nucleic Acids 17, pages 615-625.
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Xavier Siwe-Noundou, Thommas M. Musyoka, Vuyani Moses, Derek T. Ndinteh, Dumisani Mnkandhla, Heinrich Hoppe, Özlem Tastan Bishop & Rui W. M. Krause. (2019) Anti-HIV-1 integrase potency of methylgallate from Alchornea cordifolia using in vitro and in silico approaches. Scientific Reports 9:1.
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Alessandra Cavaliere, Katrin C Probst, Andrew D Westwell & Magdalena Slusarczyk. (2017) Fluorinated nucleosides as an important class of anticancer and antiviral agents. Future Medicinal Chemistry 9:15, pages 1809-1833.
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Babita Garg, O.P. Katare, Sarwar Beg, Shikha Lohan & Bhupinder Singh. (2016) Systematic development of solid self-nanoemulsifying oily formulations (S-SNEOFs) for enhancing the oral bioavailability and intestinal lymphatic uptake of lopinavir. Colloids and Surfaces B: Biointerfaces 141, pages 611-622.
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Peng Zhan, Christophe Pannecouque, Erik De Clercq & Xinyong Liu. (2015) Anti-HIV Drug Discovery and Development: Current Innovations and Future Trends. Journal of Medicinal Chemistry 59:7, pages 2849-2878.
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Julie Matz, Cécile Hérate, Jérôme Bouchet, Nelson Dusetti, Odile Gayet, Daniel Baty, Serge Benichou & Patrick Chames. (2014) Selection of Intracellular Single-Domain Antibodies Targeting the HIV-1 Vpr Protein by Cytoplasmic Yeast Two-Hybrid System. PLoS ONE 9:12, pages e113729.
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Prema C. Iyer, Jielu Zhao, Lori A. Emert-Sedlak, Kerry K. Moore, Thomas E. Smithgall & Billy W. Day. (2014) Synthesis and structure–activity analysis of diphenylpyrazolodiazene inhibitors of the HIV-1 Nef virulence factor. Bioorganic & Medicinal Chemistry Letters 24:7, pages 1702-1706.
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Liang-Tzung Lin, Wen-Chan Hsu & Chun-Ching Lin. (2014) Antiviral Natural Products and Herbal Medicines. Journal of Traditional and Complementary Medicine 4:1, pages 24-35.
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Sophie Cohen, Colette Smit, Annemarie M.C. van Rossum, Pieter L.A. Fraaij, Tom F.W. Wolfs, Sibyl P.M. Geelen, Elisabeth H. Schölvinck, Adilia Warris, Henriette J. Scherpbier & Dasja Pajkrt. (2013) Long-term response to combination antiretroviral therapy in HIV-infected children in the Netherlands registered from 1996 to 2012. AIDS 27:16, pages 2567-2575.
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Jonathan Brown, Caly Chien, Peter Timmins, Andrew Dennis, Walter Doll, Erik Sandefer, Richard Page, Richard E. Nettles, Li Zhu & Dennis Grasela. (2013) Compartmental Absorption Modeling and Site of Absorption Studies to Determine Feasibility of an Extended-Release Formulation of an HIV-1 Attachment Inhibitor Phosphate Ester Prodrug. Journal of Pharmaceutical Sciences 102:6, pages 1742-1751.
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Manel Aouri, Alexandra Calmy, Bernard Hirschel, Amalio Telenti, Thierry Buclin, Matthias Cavassini, Andri Rauch & Laurent A. Decosterd. (2013) A validated assay by liquid chromatography–tandem mass spectrometry for the simultaneous quantification of elvitegravir and rilpivirine in HIV positive patients. Journal of Mass Spectrometry 48:5, pages 616-625.
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G.G.G. de Oliveira, H.G. Ferraz, P. Severino & E.B. Souto. (2013) Compatibility studies of nevirapine in physical mixtures with excipients for oral HAART. Materials Science and Engineering: C 33:2, pages 596-602.
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D. D'alonzo & A. Guaragna. 2013. Chemical Synthesis of Nucleoside Analogues. Chemical Synthesis of Nucleoside Analogues 727 780 .
Jennifer M. Belavic. (2013) Drug updates and approvals. The Nurse Practitioner 38:2, pages 24-42.
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Liang-Tzung Lin, Ting-Ying Chen, Song-Chow Lin, Chueh-Yao Chung, Ta-Chen Lin, Guey-Horng Wang, Robert Anderson, Chun-Ching Lin & Christopher D Richardson. (2013) Broad-spectrum antiviral activity of chebulagic acid and punicalagin against viruses that use glycosaminoglycans for entry. BMC Microbiology 13:1, pages 187.
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Rebeca Bocanegra, Alicia Rodríguez-Huete, Miguel Ángel Fuertes, Marta del Álamo & Mauricio G. Mateu. (2012) Molecular recognition in the human immunodeficiency virus capsid and antiviral design. Virus Research 169:2, pages 388-410.
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Mikaela Smit, Colette Smit, Ide Cremin, Geoffrey P. Garnett, Timothy Hallett & Frank de Wolf. (2012) Could better tolerated HIV drug regimens improve patient outcome?. AIDS 26:15, pages 1953-1959.
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Michal Maes, Abraham Loyter & Assaf Friedler. (2012) Peptides that inhibit HIV-1 integrase by blocking its protein-protein interactions. FEBS Journal 279:16, pages 2795-2809.
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Hakimeh Mohammadi & Dorothee Bienzle. (2012) Pharmacological Inhibition of Feline Immunodeficiency Virus (FIV). Viruses 4:5, pages 708-724.
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Roberto Romeo, Salvatore V. Giofrè, Beatrice Macchi, Emanuela Balestrieri, Antonio Mastino, Pedro Merino, Caterina Carnovale, Giovanni Romeo & Ugo Chiacchio. (2012) Truncated Reverse Isoxazolidinyl Nucleosides: A New Class of Allosteric HIV-1 Reverse Transcriptase Inhibitors. ChemMedChem 7:4, pages 565-569.
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Xiongyu Wu, Per Öhrngren, Advait A. Joshi, Alejandro Trejos, Magnus Persson, Riina K. Arvela, Hans Wallberg, Lotta Vrang, Åsa Rosenquist, Bertil B. Samuelsson, Johan Unge & Mats Larhed. (2012) Synthesis, X-ray Analysis, and Biological Evaluation of a New Class of Stereopure Lactam-Based HIV-1 Protease Inhibitors. Journal of Medicinal Chemistry 55:6, pages 2724-2736.
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Joanne Bronson, Murali Dhar, William Ewing & Nils Lonberg. 2012. Annual Reports in Medicinal Chemistry Volume 47. Annual Reports in Medicinal Chemistry Volume 47 499 569 .
Ana L. Valino, Martín A. Palazzolo, Adolfo M. Iribarren & Elizabeth Lewkowicz. (2011) Selection of a New Whole Cell Biocatalyst for the Synthesis of 2-Deoxyribose 5-Phosphate. Applied Biochemistry and Biotechnology 166:2, pages 300-308.
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Jiwon Hwang, Laura Winkler & Robert F. Kalejta. (2011) Ubiquitin-independent proteasomal degradation during oncogenic viral infections. Biochimica et Biophysica Acta (BBA) - Reviews on Cancer 1816:2, pages 147-157.
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N. A. Kuznetsov, A. V. Kozyr, M. A. Dronina, I. V. Smirnov, E. N. Kaliberda, A. G. Mikhailova, L. D. Rumsh, O. S. Fedorova, A. G. Gabibov & A. V. Kolesnikov. (2011) Pre-steady-state kinetics of interaction of wild-type and multiple drug-resistant HIV protease with first and second generation inhibitory drugs. Doklady Biochemistry and Biophysics 440:1, pages 239-243.
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Fernando Baquero, Teresa M. Coque & Fernando de la Cruz. (2011) Ecology and Evolution as Targets: the Need for Novel Eco-Evo Drugs and Strategies To Fight Antibiotic Resistance. Antimicrobial Agents and Chemotherapy 55:8, pages 3649-3660.
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Gustavo Torres Mora, Álvaro Moreno Grau, Diego Moreno Hernández, Luis Carlos Berrocal Almanza & Enrique Carlos Ramos Clason. (2011) Efectividad de la terapia antirretroviral de gran actividad (Targa) en pacientes VIH positivos ingresados al programa de tratamiento de la IPS atención integral en la ciudad de Cartagena, Colombia.. Revista Ciencias Biomédicas 2:1, pages 44-53.
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Per Öhrngren, Xiongyu Wu, Magnus Persson, Jenny K. Ekegren, Hans Wallberg, Lotta Vrang, Åsa Rosenquist, Bertil Samuelsson, Torsten Unge & Mats Larhed. (2011) HIV-1 protease inhibitors with a tertiary alcohol containing transition-state mimic and various P2 and P1′ substituents. MedChemComm 2:8, pages 701.
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