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Expert Opinion on Pharmacotherapy Volume 12, 2011 - Issue 1
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Rapidly progressive dementias and the treatment of human prion diseases

Brian S Appleby Johns Hopkins University School of Medicine, Division of Geriatric Psychiatry and Neuropsychiatry, Department of Psychiatry and Behavioral Sciences, Meyer 279, 600 N. Wolfe St., Baltimore, MD 21287, USA +1 410 955 3902; +1 443 769 1224; [email protected]
, MD &
Constantine G Lyketsos 5300 Alpha Commons Drive, Alpha Commons Building, 4th Floor, Baltimore, MD 21224, USA
, MD MHS
Pages 1-12 | Published online: 23 Nov 2010

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Peter Hermann, Jan C. Koch & Inga Zerr. (2020) Genetic prion disease: opportunities for early therapeutic intervention with rigorous pre-symptomatic trials. Expert Opinion on Investigational Drugs 29:12, pages 1313-1316.
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Makoto Hashimoto, Gilbert Ho, Yoshiki Takamatsu, Ryoko Wada, Shuei Sugama, Masaaki Waragai, Eliezer Masliah & Takato Takenouchi. (2020) Understanding Creutzfeldt-Jackob disease from a viewpoint of amyloidogenic evolvability. Prion 14:1, pages 1-8.
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Inga Zerr & Peter Hermann. (2018) Diagnostic challenges in rapidly progressive dementia. Expert Review of Neurotherapeutics 18:10, pages 761-772.
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Vito Vetrugno, Maria Puopolo, Franco Cardone, Fiorentino Capozzoli, Anna Ladogana & Maurizio Pocchiari. (2015) The future for treating Creutzfeldt–Jakob disease. Expert Opinion on Orphan Drugs 3:1, pages 57-74.
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Articles from other publishers (24)

David C. Steffens & Kristina F. ZdanysElizabeth Wise & Constantine Lyketsos. 2022. The American Psychiatric Association Publishing Textbook of Geriatric Psychiatry. The American Psychiatric Association Publishing Textbook of Geriatric Psychiatry.
Carol K. Chan & Constantine G. Lyketsos. 2022. Reichel's Care of the Elderly. Reichel's Care of the Elderly 112 128 .
Madhuri Sharon. 2022. Nanoparticles for Therapeutic Applications. Nanoparticles for Therapeutic Applications 329 418 .
Peter Hermann & Inga Zerr. (2022) Rapidly progressive dementias — aetiologies, diagnosis and management. Nature Reviews Neurology 18:6, pages 363-376.
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Bhavesh D. Kevadiya, Brendan M. Ottemann, Midhun Ben Thomas, Insiya Mukadam, Saumya Nigam, JoEllyn McMillan, Santhi Gorantla, Tatiana K. Bronich, Benson Edagwa & Howard E. Gendelman. (2019) Neurotheranostics as personalized medicines. Advanced Drug Delivery Reviews 148, pages 252-289.
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Saima Zafar, Aneeqa Noor & Inga Zerr. 2019. Psychopharmacology of Neurologic Disease. Psychopharmacology of Neurologic Disease 47 58 .
Parmvir Parmar, Curtis L. Cooper & Daniel Kobewka. (2018) An Evaluation of Rapidly Progressive Dementia Culminating in a Diagnosis of Creutzfeldt–Jakob Disease. Case Reports in Infectious Diseases 2018, pages 1-4.
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Supriya Mahajan & Brian S. Appleby. (2017) Comprehensive and Methodical: Diagnostic and Management Approaches to Rapidly Progressive Dementia. Current Treatment Options in Neurology 19:11.
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Adalberto Studart Neto, Herval R. Soares Neto, Mateus M. Simabukuro, Davi J.F. Solla, Márcia R.R. Gonçalves, Ida Fortini, Luiz H.M. Castro & Ricardo Nitrini. (2017) Rapidly Progressive Dementia: Prevalence and Causes in a Neurologic Unit of a Tertiary Hospital in Brazil. Alzheimer Disease & Associated Disorders 31:3, pages 239-243.
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Daniela Varges, Henrike Manthey, Uta Heinemann, Claudia Ponto, Matthias Schmitz, Walter J Schulz-Schaeffer, Anna Krasnianski, Maren Breithaupt, Fabian Fincke, Katharina Kramer, Tim Friede & Inga Zerr. (2017) Doxycycline in early CJD: a double-blinded randomised phase II and observational study. Journal of Neurology, Neurosurgery & Psychiatry 88:2, pages 119-125.
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Annachiara Gandini & Maria Laura Bolognesi. 2017. Prion Protein. Prion Protein 433 453 .
Hena Khanam, Abad Ali, Mohd Asif & Shamsuzzaman. (2016) Neurodegenerative diseases linked to misfolded proteins and their therapeutic approaches: A review. European Journal of Medicinal Chemistry 124, pages 1121-1141.
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Kelcey D. Dinkel, James B. Stanton, David W. Boykin, Chad E. Stephens, Sally A. Madsen-Bouterse & David A. Schneider. (2016) Antiprion Activity of DB772 and Related Monothiophene- and Furan-Based Analogs in a Persistently Infected Ovine Microglia Culture System. Antimicrobial Agents and Chemotherapy 60:9, pages 5467-5482.
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Alvin S. Das & Wen-Quan Zou. (2016) Prions: Beyond a Single Protein. Clinical Microbiology Reviews 29:3, pages 633-658.
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Alice Uflacker, Mary C. Edmondson, Chiadi U. Onyike & Brian S. Appleby. (2015) Caregiver burden in atypical dementias: comparing frontotemporal dementia, Creutzfeldt–Jakob disease, and Alzheimer's disease. International Psychogeriatrics 28:2, pages 269-273.
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Uli S. HerrmannAnne K. SchützHamid ShiraniDanzhi HuangDino SabanMario NuvoloneBei LiBoris BallmerAndreas K. O. ÅslundJeffrey J. MasonElisabeth RushingHerbert BudkaSofie NyströmPer HammarströmAnja BöckmannAmedeo CaflischBeat H. MeierK. Peter R. NilssonSimone HornemannAdriano Aguzzi. (2015) Structure-based drug design identifies polythiophenes as antiprion compounds. Science Translational Medicine 7:299.
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Bhargavi Devineni & Chiadi U. Onyike. (2015) Young-Onset Dementia Epidemiology Applied to Neuropsychiatry Practice. Psychiatric Clinics of North America 38:2, pages 233-248.
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E. Rivero Sanz, M. A. Torralba Cabeza, F. S. Portugal & F. Garcia-Bragado. (2014) Lymphomatosis cerebri mimicking iatrogenic Creutzfeldt-Jakob disease. Case Reports 2014:sep08 1, pages bcr2013201246-bcr2013201246.
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Katja Venko, Špela Župerl & Marjana Novič. (2013) Prediction of antiprion activity of therapeutic agents with structure–activity models. Molecular Diversity 18:1, pages 133-148.
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Abelardo Q-C Araujo. (2013) Prionic diseases. Arquivos de Neuro-Psiquiatria 71:9B, pages 731-737.
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Charlene E. Gamaldo, Annum K. Shaikh & Justin C. McArthur. (2012) The Sleep-Immunity Relationship. Neurologic Clinics 30:4, pages 1313-1343.
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Ilan Margalith, Carlo Suter, Boris Ballmer, Petra Schwarz, Cinzia Tiberi, Tiziana Sonati, Jeppe Falsig, Sofie Nyström, Per Hammarström, Andreas Åslund, K. Peter R. Nilsson, Alice Yam, Eric Whitters, Simone Hornemann & Adriano Aguzzi. (2012) Polythiophenes Inhibit Prion Propagation by Stabilizing Prion Protein (PrP) Aggregates. Journal of Biological Chemistry 287:23, pages 18872-18887.
Crossref
Martin C. Michel, Piotr Radziszewski, Christian Falconer, Daniela Marschall-Kehrel & Koenraad Blot. (2012) Unexpected frequent hepatotoxicity of a prescription drug, flupirtine, marketed for about 30 years. British Journal of Clinical Pharmacology 73:5, pages 821-825.
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Sheng-Nan Wu, Ming-Chun Hsu, Yu-Kai Liao, Fang-Tzu Wu, Yuh-Jyh Jong & Yi-Ching Lo. (2012) Evidence for Inhibitory Effects of Flupirtine, a Centrally Acting Analgesic, on Delayed Rectifier K + Currents in Motor Neuron-Like Cells . Evidence-Based Complementary and Alternative Medicine 2012, pages 1-10.
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