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Expert Opinion on Pharmacotherapy Volume 12, 2011 - Issue 4
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Drug Evaluations

Treatment of osteoporosis and reduction in risk of invasive breast cancer in postmenopausal women with raloxifene

Seung Sang Ko Georgetown University Medical Center, Lombardi Comprehensive Cancer Center, Department of Oncology, 3970 Reservoir Rd NW., Research Building, Suite E204 A, Washington, DC 20057, USA; Kwandong University College of Medicine, Cheil General Hospital, Department of Surgery, 1-19 Mukjeong-dong Jung-gu Seoul (Seoul 100-380 Korea)
, MD PhD &
V Craig Jordan Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Vincent T. Lombardi Chair of Translational Cancer Research, Vice Chair of Department of Oncology, Professor of Oncology and Pharmacology, 3970 Reservoir Rd NW., Research Building, Suite E501, Washington, DC 20057, USA +1 202.687.2897; +1 202.687.6402; [email protected]
, OBE PhD DSc FMedSci
Pages 657-674 | Published online: 07 Feb 2011

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Xinhui Du, Na Gao & Xiaoyong Song. (2021) Bioadhesive polymer/lipid hybrid nanoparticles as oral delivery system of raloxifene with enhancive intestinal retention and bioavailability. Drug Delivery 28:1, pages 252-260.
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Articles from other publishers (20)

Ramin Riahi Madvar & Mohammad Ali Taher. (2024) Preparation of fluorescent sensor based on Zn metal-organic framework for detection and determination of raloxifene as an anticancer drug. Environmental Research 240, pages 117449.
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Karen M Tuesley, Penelope M Webb, Melinda M Protani, Katrina Spilsbury, Sallie-Anne Pearson, Michael D Coory, Peter Donovan, Christopher Steer, Louise M Stewart, Nirmala Pandeya & Susan J Jordan. (2022) Nitrogen-based Bisphosphonate Use and Ovarian Cancer Risk in Women Aged 50 Years and Older. JNCI: Journal of the National Cancer Institute 114:6, pages 878-884.
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Shu-ting Lin, Yi-zhong Li, Xiao-qi Sun, Qian-qian Chen, Shun-fa Huang, Shu Lin & Si-qing Cai. (2021) Update on the Role of Neuropeptide Y and Other Related Factors in Breast Cancer and Osteoporosis. Frontiers in Endocrinology 12.
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Masoumeh Ghalkhani, Saeed Shahrokhian & Mostafa Navabi. (2021) Development of an electrochemical sensor based on (rGO-CNT) nanocomposite for raloxifene analysis. Materials Chemistry and Physics 263, pages 124131.
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Xiao-Yu Qi, Hao Liu, Dong-Dong Bi, Xiang-Tao Wang, Yi-Fei Guo, Ting Hao, Bao-Xin Zhang, Xing-Guo Wang & Mei-Hua Han. (2019) Combined administration on You-Gui Yin and low-dose Raloxifene partially attenuates the bone loss in ovariectomized mice through the proliferation and osteogenic differentiation of bone marrow stromal cells. Phytomedicine 53, pages 286-293.
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Imaneh KhorsandReyhaneh KashefMasumeh GhazanfarpourElaheh MansouriSareh DashtiTalat Khadivzadeh. (2018) The Beneficial and Adverse Effects of Raloxifene in Menopausal Women: A Mini Review. Journal of Menopausal Medicine 24:3, pages 183.
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Meihua Han, Xiaoyu Qi, Dongdong Bi, Yijing Li, Yifei Guo, Xiangtao Wang & Li Feng. (2018) Administration of raloxifene hydrochloride nanosuspensions partially attenuates bone loss in ovariectomized mice. RSC Advances 8:42, pages 23748-23756.
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Abul Kalam, Sushama Talegaonkar & Divya Vohora. (2017) Effects of raloxifene against letrozole-induced bone loss in chemically-induced model of menopause in mice. Molecular and Cellular Endocrinology 440, pages 34-43.
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Saeed Shahrokhian, Masoumeh Ghalkhani, Hamed Balotf & Razieh Salimian. (2016) Application of glassy carbon electrode modified with a carbon nanoparticle/melamine thin film for voltammetric determination of raloxifene. Journal of Electroanalytical Chemistry 780, pages 126-133.
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Sang Jun Han, Khurshida Begum, Charles E. Foulds, Ross A. Hamilton, Suzanna Bailey, Anna Malovannaya, Doug Chan, Jun Qin & Bert W. O’Malley. (2016) The Dual Estrogen Receptor α Inhibitory Effects of the Tissue-Selective Estrogen Complex for Endometrial and Breast Safety . Molecular Pharmacology 89:1, pages 14-26.
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Xiaotong Zhou, Shaoxiang Wang, Hua Sun & Baojian Wu. (2015) Sulfonation of raloxifene in HEK293 cells overexpressing SULT1A3: Involvement of breast cancer resistance protein (BCRP/ABCG2) and multidrug resistance-associated protein 4 (MRP4/ABCC4) in excretion of sulfate metabolites. Drug Metabolism and Pharmacokinetics 30:6, pages 425-433.
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Samy A.F. Morad & Myles C. Cabot. (2015) Tamoxifen regulation of sphingolipid metabolism—Therapeutic implications. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 1851:9, pages 1134-1145.
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Elena Huerta-Ramos, Susana Ochoa, Mercedes Roca, Eva Miquel & Judith Usall. (2015) The effect of raloxifene on symptoms and cognitive functioning in a postmenopausal schizophrenia patient: a case report. Archives of Women's Mental Health 18:2, pages 259-261.
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Juliana Q. Reimão, Danilo C. Miguel, Noemi N. Taniwaki, Cristiana T. Trinconi, Jenicer K. U. Yokoyama-Yasunaka & Silvia R. B. Uliana. (2014) Antileishmanial Activity of the Estrogen Receptor Modulator Raloxifene. PLoS Neglected Tropical Diseases 8:5, pages e2842.
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Mi Hye Kim, You Yeon Choi, Jae Min Han, Hyoun-su Lee, Seong Bin Hong, Seok-geun Lee & Woong Mo Yang. (2014) Ameliorative effects of Schizandra chinensis on osteoporosis via activation of estrogen receptor (ER)-α/-β. Food Funct. 5:7, pages 1594-1601.
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Ming Fang, Xin-Chi Wu & Wenlong Huang. (2013) Raloxifene Upregulated Mesangial Cell MMP-2 Activity via ER-β Through Transcriptional Regulation. Cell Biochemistry and Biophysics 67:2, pages 607-613.
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Z.D. Yang, J. Yu & Q. Zhang. (2013) Effects of raloxifene on cognition, mental health, sleep and sexual function in menopausal women: A systematic review of randomized controlled trials. Maturitas 75:4, pages 341-348.
Crossref
Hongyun Lu, Hong Liu, Fang Hu, Lingling Zou, Shunkui Luo & Liao Sun. (2013) Independent Association between Nonalcoholic Fatty Liver Disease and Cardiovascular Disease: A Systematic Review and Meta-Analysis. International Journal of Endocrinology 2013, pages 1-7.
Crossref
A. Cleve, K.-H. Fritzemeier, B. Haendler, N. Heinrich, C. Möller, W. Schwede & T. Wintermantel. 2012. Sex and Gender Differences in Pharmacology. Sex and Gender Differences in Pharmacology 543 587 .
. (2012) Current World Literature. Current Opinion in Obstetrics & Gynecology 24:1, pages 49-55.
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