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Drug Evaluations

Lubiprostone for the treatment of opioid-induced bowel dysfunction

, MD & , MD
Pages 983-990 | Published online: 09 Mar 2011

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Bill H. McCarberg. (2013) Overview and Treatment of Opioid-Induced Constipation. Postgraduate Medicine 125:4, pages 7-17.
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John Cuppoletti, Danuta H. Malinowska & Ryuji Ueno. 2020. Studies of Epithelial Transporters and Ion Channels. Studies of Epithelial Transporters and Ion Channels 495 522 .
Egilius L.H. SpieringsRichard RauckRandall BrewerStefano MarcuardRicardo Vallejo. (2016) Long-Term Safety and Efficacy of Lubiprostone in Opioid-induced Constipation in Patients with Chronic Noncancer Pain. Pain Practice 16:8, pages 985-993.
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Fan Li, Tao Fu, Wei-Dong Tong, Bao-Hua Liu, Chun-Xue Li, Yu Gao, Jin-Song Wu, Xiang-Feng Wang & An-Ping Zhang. (2016) Lubiprostone Is Effective in the Treatment of Chronic Idiopathic Constipation and Irritable Bowel Syndrome. Mayo Clinic Proceedings 91:4, pages 456-468.
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John Cuppoletti, Danuta H. Malinowska & Ryuji Ueno. 2016. Ion Channels and Transporters of Epithelia in Health and Disease. Ion Channels and Transporters of Epithelia in Health and Disease 491 518 .
Z. Li, J. V. Pergolizzi, R. P. Huttner, G. Zampogna, F. Breve & R. B. Raffa. (2015) Management of opioid-induced constipation in pregnancy: a concise review with emphasis on the PAMORAs. Journal of Clinical Pharmacy and Therapeutics 40:6, pages 615-619.
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Mellar Davis & Pamela Gamier. (2015) New Options in Constipation Management. Current Oncology Reports 17:12.
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Jakob Lykke Poulsen, Christina Brock, Anne Estrup Olesen, Matias Nilsson & Asbjørn Mohr Drewes. (2015) Evolving paradigms in the treatment of opioid-induced bowel dysfunction. Therapeutic Advances in Gastroenterology 8:6, pages 360-372.
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Mazen M Jamal, Atoya B Adams, Jan-Peter Jansen & Lynn R Webster. (2015) A Randomized, Placebo-Controlled Trial of Lubiprostone for Opioid-Induced Constipation in Chronic Noncancer Pain. American Journal of Gastroenterology 110:5, pages 725-732.
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Nicholas Wilson & Ron Schey. (2015) Lubiprostone in constipation: clinical evidence and place in therapy. Therapeutic Advances in Chronic Disease 6:2, pages 40-50.
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Lalit Kumar, Chris Barker & Anton Emmanuel. (2014) Opioid-Induced Constipation: Pathophysiology, Clinical Consequences, and Management. Gastroenterology Research and Practice 2014, pages 1-6.
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Flannery Fielding, Tanya M Sanford & Mellar P Davis. (2013) Achieving effective control in cancer pain: a review of current guidelines. International Journal of Palliative Nursing 19:12, pages 584-591.
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Scott R. Armstrong, Christina B. Campbell, Carrie L. Richardson, Ross G. Vickery, Pamela R. Tsuruda, Daniel D. Long, Sharath S. Hegde & David T. Beattie. (2013) The in vivo pharmacodynamics of the novel opioid receptor antagonist, TD-1211, in models of opioid-induced gastrointestinal and CNS activity. Naunyn-Schmiedeberg's Archives of Pharmacology 386:6, pages 471-478.
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John Cuppoletti, Jayati Chakrabarti, Kirti Tewari & Danuta H. Malinowska. (2012) Methadone but not Morphine Inhibits Lubiprostone-Stimulated Cl− Currents in T84 Intestinal Cells and Recombinant Human ClC-2, but not CFTR Cl− Currents. Cell Biochemistry and Biophysics 66:1, pages 53-63.
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Yunyun Yuan, Orgil Elbegdorj, Jianyang Chen, Shashidhar K. Akubathini, Feng Zhang, David L. Stevens, Irina O. Beletskaya, Krista L. Scoggins, Zhenxian Zhang, Phillip M. Gerk, Dana E. Selley, Hamid I. Akbarali, William L. Dewey & Yan Zhang. (2012) Design, Synthesis, and Biological Evaluation of 17-Cyclopropylmethyl-3,14β-dihydroxy-4,5α-epoxy-6β-[(4′-pyridyl)carboxamido]morphinan Derivatives as Peripheral Selective μ Opioid Receptor Agents. Journal of Medicinal Chemistry 55:22, pages 10118-10129.
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Christina Brock, Søren Schou Olesen, Anne Estrup Olesen, Jens Brøndum Frøkjaer, Trine Andresen & Asbjørn Mohr Drewes. (2012) Opioid-Induced Bowel Dysfunction. Drugs 72:14, pages 1847-1865.
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