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Drug Evaluations

Enoxaparin: a pharmacologic and clinical review

, MD & , MD FACC
Pages 1157-1170 | Published online: 07 Apr 2011

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Javier Martínez González, Mayte Monreal, Ignacio Ayani Almagia, Jordi Llaudó Garín, Lourdes Ochoa Díaz de Monasterioguren & Ibón Gutierro Adúriz. (2018) Bioequivalence of a biosimilar enoxaparin sodium to Clexane® after single 100 mg subcutaneous dose: results of a randomized, double-blind, crossover study in healthy volunteers. Drug Design, Development and Therapy 12, pages 575-582.
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Articles from other publishers (27)

Katrin Zöller, Flavia Laffleur, Victor Claus, Patrick Knoll, Dennis To & Andreas Bernkop-Schnürch. (2023) Development and in vivo evaluation of nanoemulsions for oral delivery of low molecular weight heparin. Journal of Drug Delivery Science and Technology 86, pages 104686.
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Katherine Kramme, Paya Sarraf, Saad Shebrain & Gitonga Munene. (2021) Safety and Efficacy of Prophylactic Enoxaparin Adjusted by Anti-Factor Xa Peak Levels in Pancreatic Surgery. The American Surgeon 89:2, pages 300-308.
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Mehdi Shafiei, Masih Sabouri, Bahram Aminmansour, Majid Rezvani, Mehdi Mahmoodkhani, Peiman Rahmani, Babak Karami, Arman Sourani & Mina Foroughi. (2022) Comparison between rivaroxaban versus enoxaparin for venous thromboembolism prophylaxis following spine surgeries, a randomized clinical trial. Journal of Clinical Neuroscience 105, pages 51-57.
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Meng Zhang, Xiang Zhang, Chunlan Wang, Yangfang Shen & Jianan Fu. (2022) The Role of Jinhuang Powder to Prevent Adverse Effects of Subcutaneous Injection of Enoxaparin Sodium. Emergency Medicine International 2022, pages 1-6.
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Sumit Saxena, Manu Chaudhary, Saransh Chaudhary & Anmol Aggarwal. (2022) Bioequivalence of a biosimilar enoxaparin ( Cloti‐Xa™ ) and its innovator (Clexane ® ): A single‐dose , randomized, double‐blind , two‐period , two‐treatment , two‐sequence , crossover, balanced study in healthy human subjects . Pharmacology Research & Perspectives 10:4.
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Lei Chen, Wen Zhu, Na Yan, Yan Guo, Lin Yi, Yilan Ouyang & Zhenqing Zhang. (2022) Analysis of heparinase derived LMWH products using a MHC 2D LC system linked to Q-TOF MS. Journal of Pharmaceutical and Biomedical Analysis 212, pages 114616.
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Patrick Lu, Karl-Anton Harms, Eldho Paul, Hadley Bortz, Cheng Lo & Heather Cleland. (2021) Venous thromboembolism in burns patients: Are we underestimating the risk and underdosing our prophylaxis?. Journal of Plastic, Reconstructive & Aesthetic Surgery 74:8, pages 1814-1823.
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Bo-Xia Li, Shi-Dong Liu, Liang Qi, Shusen Sun, Wei Sun, Yuan-Min Li, Bing Song & Xin-An Wu. (2020) Comparison of different bridging anticoagulation therapies used after mechanical heart valve replacement in Chinese patients - a prospective cohort study. Journal of Cardiothoracic Surgery 15:1.
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Lauren E. Corona, Udit Singhal, Khaled Hafez, Lindsey A. Herrel, Samuel D. Kaffenberger, Jeffrey S. Montgomery, Todd M. Morgan, Alon Z. Weizer, Yongmei Qin & Sapan N. Ambani. (2020) Rethinking the one-size-fits-most approach to venous thromboembolism prophylaxis after radical cystectomy. Urologic Oncology: Seminars and Original Investigations 38:10, pages 797.e1-797.e6.
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Katherine Kramme, Paya Sarraf & Gitonga Munene. (2020) Prophylactic Enoxaparin Adjusted by Anti-Factor Xa Peak Levels Compared with Recommended Thromboprophylaxis and Rates of Clinically Evident Venous Thromboembolism in Surgical Oncology Patients. Journal of the American College of Surgeons 230:3, pages 314-321.
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Jacob E. Choby, Andrew J. Monteith, Lauren E. Himmel, Paris Margaritis, Jana K. Shirey-Rice, Andrea Pruijssers, Rebecca N. Jerome, Jill Pulley & Eric P. Skaar. (2019) A Phenome-Wide Association Study Uncovers a Pathological Role of Coagulation Factor X during Acinetobacter baumannii Infection . Infection and Immunity 87:5.
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Audis BetheaElliot AdamsFrank C. Lucente, Damayanti SamantaJulton Tomanguillo Chumbe. (2018) Improving Pharmacologic Prevention of VTE in Trauma: IMPACT-IT QI Project. The American Surgeon 84:6, pages 1097-1104.
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Joel M. Baumgartner, Shonté McKenzie, Shanna Block, Todd W. Costantini & Andrew M. Lowy. (2018) Prophylactic enoxaparin doses may be inadequate in patients undergoing abdominal cancer surgery. Journal of Surgical Research 221, pages 183-189.
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Shifaza Mohamed & Deirdre Coombe. (2017) Heparin Mimetics: Their Therapeutic Potential. Pharmaceuticals 10:4, pages 78.
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Tammy R. Kopelman, Jarvis W. Walters, James N. Bogert, Usmaan Basharat, Paola G. Pieri, Karole M. Davis, Asia N. Quan, Sydney J Vail & Melissa A. Pressman. (2017) Goal directed enoxaparin dosing provides superior chemoprophylaxis against deep vein thrombosis. Injury 48:5, pages 1088-1092.
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S K Zyryanov & E A Ushkalova. (2016) Enoxaparin is a low-molecular-weight heparin with a complex chemical structure and various non-anticoagulant properties. Terapevticheskii arkhiv 88:12, pages 109-115.
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George A. Singer, Gina Riggi, Charles A. Karcutskie, Tanaz M. Vaghaiwalla, Howard M. Lieberman, Enrique Ginzburg, Nicholas Namias & Edward B. Lineen. (2016) Anti-Xa–guided enoxaparin thromboprophylaxis reduces rate of deep venous thromboembolism in high-risk trauma patients. Journal of Trauma and Acute Care Surgery 81:6, pages 1101-1108.
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Allison E. Berndtson, Todd W. Costantini, James Lane, Kevin Box & Raul Coimbra. (2016) If some is good, more is better. Journal of Trauma and Acute Care Surgery 81:6, pages 1095-1100.
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Turgut Cavusoglu, Kemal Kismet, Namik Ozcan, Berkay Kucuk, Aziz Mutlu Barlas, Bahadir Osman Bozkirli, Pinar Celepli, Mehmet Senes, Serkan Bolat & Sema Hucumenoglu. (2016) The effects of enoxaparin on the liver in experimental pneumoperitoneum model. Acta Cirurgica Brasileira 31:11, pages 736-743.
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Ruben Vardanyan & Victor Hruby. 2016. Synthesis of Best-Seller Drugs. Synthesis of Best-Seller Drugs 383 412 .
Matthew D Jose, Henrietta Longmuir, Benjamin Dodds, Luke Bereznicki, Ritam Prasad, Tracey J Batt, Giovanni FM Strippoli & Suetonia C Palmer. (2015) Anticoagulation for people receiving long-term haemodialysis. Cochrane Database of Systematic Reviews.
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Cynthia M. Panek, Reid K. Nakamura & Domenico Bianco. (2015) Use of enoxaparin in dogs with primary immune-mediated hemolytic anemia: 21 cases. Journal of Veterinary Emergency and Critical Care 25:2, pages 273-277.
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Michel Kindo, Sébastien Gerelli, Tam Hoang Minh, Min Zhang, Nicolas Meyer, Tarek Announe, Jonathan Bentz, Ziad Mansour, Arnaud Mommerot, Hélène Petit-Eisenmann, Hélène Kremer, Olivier Collange, Julien Pottecher, Mircea Cristinar, Jean-Claude Thiranos, Philippe Billaud & Jean-Philippe Mazzucotelli. (2014) Exclusive Low-Molecular-Weight Heparin as Bridging Anticoagulant After Mechanical Valve Replacement. The Annals of Thoracic Surgery 97:3, pages 789-795.
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Geon-Hyeong Kim, Beom-Yong Park, Tae-Yong Bae, Jin-Woo Kang & Yong In. (2013) Can Enoxaparin Reduce Thromboembolism Related Events After Primary TKA In Asian Patients?. The Journal of Arthroplasty 28:10, pages 1862-1867.
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Todd W. Costantini, Emily Min, Kevin Box, Vy Tran, Robert D. Winfield, Dale Fortlage, Jay Doucet, Vishal Bansal & Raul Coimbra. (2013) Dose adjusting enoxaparin is necessary to achieve adequate venous thromboembolism prophylaxis in trauma patients. Journal of Trauma and Acute Care Surgery 74:1, pages 128-135.
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Randall N. Willard, Antonio E. Muñiz & Francis Chuidian. (2012) Delayed subdural hematoma after receiving enoxaparin for prevention of thromboembolic events from high-risk surgery. The American Journal of Emergency Medicine 30:6, pages 1017.e5-1017.e8.
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Lei Chen, Wen Zhu, Na Yang, Yan Guo, Lin Yi, Yilan Ouyang & Zhenqing Zhang. (2021) Analysis of Heparinase Derived LMWH Products Using a MHC 2D LC System Linked to Q-TOF MS. SSRN Electronic Journal.
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