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New therapeutic options for onychomycosis

, MD PhD FAAD FRCP(C) & , HBSc
Pages 1131-1142 | Published online: 25 Apr 2012

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Snigdha Chakraborty, Sanshita & Inderbir Singh. (2023) Therapeutic treatment strategies for the management of onychomycosis: a patent perspective. Expert Opinion on Therapeutic Patents 33:9, pages 613-630.
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Xuelin Wu & Yongxuan Hu. (2022) Photodynamic Therapy for the Treatment of Fungal Infections. Infection and Drug Resistance 15, pages 3251-3266.
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Julianne M Falotico & Shari R Lipner. (2022) Updated Perspectives on the Diagnosis and Management of Onychomycosis. Clinical, Cosmetic and Investigational Dermatology 15, pages 1933-1957.
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Marwa Abdallah, Mustafa M. Abu-Ghali, Mohamed Taha El-Sayed & Marwa Y. Soltan. (2022) Fractional CO2-assisted photodynamic therapy improves the clinical outcome and patient’s satisfaction in toenail onychomycosis treatment: an intra-patient comparative single-center study. Journal of Dermatological Treatment 33:1, pages 542-549.
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Aditya K. Gupta & Nadia Stec. (2019) Emerging drugs for the treatment of onychomycosis. Expert Opinion on Emerging Drugs 24:4, pages 213-220.
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Shari R. Lipner. (2019) Pharmacotherapy for onychomycosis: new and emerging treatments. Expert Opinion on Pharmacotherapy 20:6, pages 725-735.
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Essam Bakr Abd El-Aal, Hamed Mohamed Abdo, Shady Mahmoud Ibrahim & Mostafa Taha Eldestawy. (2019) Fractional carbon dioxide laser assisted delivery of topical tazarotene versus topical tioconazole in the treatment of onychomycosis. Journal of Dermatological Treatment 30:3, pages 277-282.
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Alessio Nocentini, Claudiu T. Supuran & Jean-Yves Winum. (2018) Benzoxaborole compounds for therapeutic uses: a patent review (2010- 2018). Expert Opinion on Therapeutic Patents 28:6, pages 493-504.
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A. Shemer, A. K. Gupta, B. Amichai, R. Farhi, R. Baran, C. R. Daniel$suffix/text()$suffix/text(), D. Daigle & K. A. Foley. (2016) An open comparative study of nail drilling as adjunctive treatment for toenail onychomycosis. Journal of Dermatological Treatment 27:5, pages 480-483.
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Aditya K. Gupta & Sarah G. Versteeg. (2016) Tavaborole – a treatment for onychomycosis of the toenails. Expert Review of Clinical Pharmacology 9:9, pages 1145-1152.
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Rungsima Wanitphakdeedecha, Kanchalit Thanomkitti, Sumanas Bunyaratavej & Woraphong Manuskiatti. (2016) Efficacy and safety of 1064-nm Nd:YAG laser in treatment of onychomycosis. Journal of Dermatological Treatment 27:1, pages 75-79.
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Charlotte E LaSenna & Antonella Tosti. (2015) Patient considerations in the management of toe onychomycosis – role of efinaconazole. Patient Preference and Adherence 9, pages 887-891.
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Sphoorthi Jinna & Justin Finch. (2015) Spotlight on tavaborole for the treatment of onychomycosis. Drug Design, Development and Therapy 9, pages 6185-6190.
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Rania Elkeeb, Xiaoying Hui, Narasimha Murthy & Howard I Maibach. (2014) Emerging Topical Onychomycosis Therapies – Quo Vadis?. Expert Opinion on Emerging Drugs 19:4, pages 489-495.
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Min Ju Choi, Zhenlong Zheng, Boncheol Goo & Sung Bin Cho. (2014) Antifungal effects of a 1444-nm neodymium:Yttrium–aluminum–garnet laser on onychomycosis: a pilot study. Journal of Dermatological Treatment 25:4, pages 294-297.
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María Victoria Castelli, Estefanía Butassi, María Candida Monteiro, Laura A Svetaz, Francisca Vicente & Susana A Zacchino. (2014) Novel antifungal agents: a patent review (2011 – present). Expert Opinion on Therapeutic Patents 24:3, pages 323-338.
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Xiaoying Hui, Åke Lindahl, Sonia Lamel & Howard I. Maibach. (2013) Onychopharmacokinetics of terbinafine hydrochloride penetration from a novel topical formulation into the human nail in vitro. Drug Development and Industrial Pharmacy 39:9, pages 1401-1407.
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Articles from other publishers (53)

Nagat Sobhy, Heba talla Eweed & Salma Samir Omar. (2022) Fractional CO2 laser - assisted methylene blue photodynamic therapy is a potential alternative therapy for onychomycosis in the era of antifungal resistance. Photodiagnosis and Photodynamic Therapy 40, pages 103149.
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Waranyoo PrasongLalita MatthapanSumanas BunyaratavejCharussri LeeyaphanKamonpan LertrujiwanitSalisa Supcharoenkul. (2022) Efficacy of a Newly Developed Inward Airflow Safety Cabinet to Prevent the Spread of Infected Nail Dust Particles During Mechanical Nail Reduction in Onychomycosis. Journal of the American Podiatric Medical Association 112:2.
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Yashwant Giri, Amulyaratna Behera, Biswaranjan Mohanty, Gurudutta Pattnaik & S.K. Habibullah. (2022) Transungual Drug Delivery System for the Topical Treatment of Onychomycosis: A Review. Drug Delivery Letters 12:1, pages 2-18.
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Paolo Coghi. 2022. Fundamentals and Applications of Boron Chemistry. Fundamentals and Applications of Boron Chemistry 155 201 .
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Paolo Saul Coghi, Yinghuai Zhu, Hongming Xie, Narayan S. Hosmane & Yingjun Zhang. (2021) Organoboron Compounds: Effective Antibacterial and Antiparasitic Agents. Molecules 26:11, pages 3309.
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Rabia Aslam, Talib Hussain, Abid Mehmood Yousaf, Muhammad U. Ghori, Ikram U. Khan, Syed A.A. Rizvi & Yasser Shahzad. (2021) Onychomycosis: Current Understanding and Strategies for Enhancing Drug Delivery into Human Nail Tissue. Current Drug Research Reviews 13:1, pages 25-35.
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Akihiro Nakamura, Satoko Hirakawa, Hiroaki Nagai & Katsuhiro Inagaki. (2021) A comparative study between two antifungal agents, Luliconazole and Efinaconazole, of their preventive effects in a Trichophyton -infected guinea pig onychomycosis model . Medical Mycology 59:3, pages 289-295.
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A.K. Gupta, N. Stec, R.C. Summerbell, N.H. Shear, V. Piguet, A. Tosti & B.M. Piraccini. (2020) Onychomycosis: a review. Journal of the European Academy of Dermatology and Venereology 34:9, pages 1972-1990.
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R. Aggarwal, M. Targhotra, B. Kumar, P.K. Sahoo & M.K. Chauhan. (2020) Treatment and management strategies of onychomycosis. Journal de Mycologie Médicale 30:2, pages 100949.
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Anton Valkov, Michael Zinigrad, Alexander Sobolev & Marina Nisnevitch. (2020) Keratin Biomembranes as a Model for Studying Onychomycosis. International Journal of Molecular Sciences 21:10, pages 3512.
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Agrawal Vikas, Patel Rashmin, Patel Mrunali, Rahul B. Chavan & Thanki Kaushik. (2020) Mechanistic Insights of Formulation Approaches for the Treatment of Nail Infection: Conventional and Novel Drug Delivery Approaches. AAPS PharmSciTech 21:2.
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L. Nijenhuis‐Rosien, N. Kleefstra, P.R. van Dijk, M.J.H.M. Wolfhagen, K.H. Groenier, H.J.G. Bilo & G.W.D. Landman. (2019) Laser therapy for onychomycosis in patients with diabetes at risk for foot ulcers: a randomized, quadruple‐blind, sham‐controlled trial ( LASER ‐1) . Journal of the European Academy of Dermatology and Venereology 33:11, pages 2143-2150.
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Andrey V. Belikov, Yulia V. Semyashkina, Mikhail A. Modin, Mark L. Gelfond & Elena I. Sergeeva. (2018) Photodynamic therapy of onychomycosis by high-intensive LED light of wavelength 660 ± 10 nm. Photodynamic therapy of onychomycosis by high-intensive LED light of wavelength 660 ± 10 nm.
Rupinder K. Dhamoon, Harvinder Popli & Madhu Gupta. (2019) Novel Drug Delivery Strategies for the Treatment of Onychomycosis. Pharmaceutical Nanotechnology 7:1, pages 24-38.
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Prabhuodeyara Math Gurubasavaraj & Jasmith Shivayya Charantimath. (2019) Recent Advances in Azole Based Scaffolds as Anticandidal Agents. Letters in Drug Design & Discovery 16:5, pages 492-501.
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Shari R. Lipner & Richard K. Scher. (2019) Onychomycosis. Journal of the American Academy of Dermatology 80:4, pages 853-867.
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Antonio Zalacain, Alejandra Merlos, Elena Planell, Erica G. Cantadori, Teresa Vinuesa & Miguel Viñas. (2017) Clinical laser treatment of toenail onychomycoses. Lasers in Medical Science 33:4, pages 927-933.
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Emily L Larkin, Sharvari Dharmaiah & Mahmoud A Ghannoum. (2018) Biofilms and beyond: expanding echinocandin utility. Journal of Antimicrobial Chemotherapy 73:suppl_1, pages i73-i81.
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Mohamed Taha & Adel Botros Zaghloul. 2018. Pigmented Ethnic Skin and Imported Dermatoses. Pigmented Ethnic Skin and Imported Dermatoses 37 51 .
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Anil Kumar Bhatta, Uma Keyal, Xiuli Wang & Emese Gellén. (2016) A review of the mechanism of action of lasers and photodynamic therapy for onychomycosis. Lasers in Medical Science 32:2, pages 469-474.
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Hans P. Seidl, Andreas Jäckel, Julia Müller, Martin Schaller, Claudia Borelli & Annemarie Polak. (2015) Sporicidal effect of amorolfine and other antimycotics used in the therapy of fungal nail infections. Mycoses 58:10, pages 610-619.
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Guilherme Bueno de Oliveira, João Roberto Antonio, Carlos Roberto Antonio & Fernanda Alves Tomé. (2015) The association of fractional CO2 laser 10.600nm and photodynamic therapy in the treatment of onychomycosis. Anais Brasileiros de Dermatologia 90:4, pages 468-471.
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