Citations (57)
Keep up to date with the latest research on this topic with citation updates for this article.
Read on this site (2)
Marta Bosia, Alessandro Pigoni & Roberto Cavallaro. (2015) Genomics and epigenomics in novel schizophrenia drug discovery: translating animal models to clinical research and back. Expert Opinion on Drug Discovery 10:2, pages 125-139.
Read now
Read now
Lieve Desbonnet, Colm MP O’Tuathaigh & John L Waddington. (2012) Modeling schizophrenia: uncovering novel therapeutic targets. Expert Review of Clinical Pharmacology 5:6, pages 667-676.
Read now
Read now
Articles from other publishers (55)
Carlo Magistri & Cristiano Mellini. (2023) Clozapine-Associated Agranulocytosis. Journal of Clinical Psychopharmacology 43:6, pages 527-533.
Crossref
Crossref
Flora Marchandise, Coralie Lo Presti, Matthieu Peretti, Oriane De Mauroy, Clémence Lacroix, Camille Heyries, Anthony Loru, Elodie Bambina, Virginie Aghazarian & Stéphanie Guise-Honoré. (2023) Découverte d’une cardiomyopathie dilatée chez un patient schizophrène traité par clozapine. Le Pharmacien Clinicien 58:1, pages 59-64.
Crossref
Crossref
Matcheri S. Keshavan, Burhan A. Khan & Jaya L. Padmanabhan. 2023. Encyclopedia of Mental Health. Encyclopedia of Mental Health
94
107
.
Jiao-li Ma, Xu-ming Zhou, Jia-lin Chen, Jie-xin Shi, Hui-cheng Cheng, Peng-hu Guo & Hong-bing Ji. (2022) Directing group strategies in rhodium-catalyzed C–H amination. Organic & Biomolecular Chemistry 20:38, pages 7554-7576.
Crossref
Crossref
Andrea de Bartolomeis, Licia Vellucci, Annarita Barone, Mirko Manchia, Vincenzo De Luca, Felice Iasevoli & Christoph U. Correll. (2022) Clozapine’s multiple cellular mechanisms: What do we know after more than fifty years? A systematic review and critical assessment of translational mechanisms relevant for innovative strategies in treatment-resistant schizophrenia. Pharmacology & Therapeutics 236, pages 108236.
Crossref
Crossref
Ronald J. Gurrera, Priya F. Gearin, Jonathan Love, Kevin J. Li, Ashley Xu, Faith H. Donaghey & Matthew R. Gerace. (2022) Recognition and management of clozapine adverse effects: A systematic review and qualitative synthesis. Acta Psychiatrica Scandinavica 145:5, pages 423-441.
Crossref
Crossref
Amina Aissa, Rahma Jouini, Uta Ouali, Yosra Zgueb, Fethi Nacef & Zouhaier El Hechmi. (2022) Clinical predictors of response to clozapine in Tunisian patients with treatment resistant schizophrenia. Comprehensive Psychiatry 112, pages 152280.
Crossref
Crossref
Feng Zhang, Liwen Han, Jiazhen Wang, Minglei Shu, Kechun Liu, Yun Zhang, ChungDer Hsiao, Qingping Tian & Qiuxia He. (2021) Clozapine Induced Developmental and Cardiac Toxicity on Zebrafish Embryos by Elevating Oxidative Stress. Cardiovascular Toxicology 21:5, pages 399-409.
Crossref
Crossref
Nagara Takao, Toshiya Murai & Hironobu Fujiwara. (2021) Treatment-resistant schizophrenia characterised by dopamine supersensitivity psychosis and efficacy of asenapine. BMJ Case Reports 14:4, pages e242495.
Crossref
Crossref
Hiroshi Kimura, Nobuhisa Kanahara & Masaomi Iyo. (2021) Rationale and neurobiological effects of treatment with antipsychotics in patients with chronic schizophrenia considering dopamine supersensitivity. Behavioural Brain Research 403, pages 113126.
Crossref
Crossref
Fatma Sa'eed El-Tokhy, Mona M.A. Abdel-Mottaleb, Elsayed A. El-Ghany & Ahmed S. Geneidi. (2021) Transdermal delivery of second-generation antipsychotics for management of schizophrenia; disease overview, conventional and nanobased drug delivery systems. Journal of Drug Delivery Science and Technology 61, pages 102104.
Crossref
Crossref
Samskruthi Madireddy & Sahithi Madireddy. (2020) Regulation of Reactive Oxygen Species-Mediated Damage in the Pathogenesis of Schizophrenia. Brain Sciences 10:10, pages 742.
Crossref
Crossref
Vijayasree V. Giridharan, Giselli Scaini, Gabriela D. Colpo, Tejaswini Doifode, Omar F. Pinjari, Antônio L. Teixeira, Fabricia Petronilho, Danielle Macêdo, João Quevedo & Tatiana Barichello. (2020) Clozapine Prevents Poly (I:C) Induced Inflammation by Modulating NLRP3 Pathway in Microglial Cells. Cells 9:3, pages 577.
Crossref
Crossref
Edoardo G Ostinelli, Caroline Zangani & Marco Solmi. (2019) Clozapine for persistent aggressive behaviour or agitation in people with schizophrenia. Cochrane Database of Systematic Reviews.
Crossref
Crossref
Leyla Karadurmus, Duru Kır, Sevinc Kurbanoglu & Sibel A. Ozkan. (2019) Electrochemical Analysis of Antipsychotics. Current Pharmaceutical Analysis 15:5, pages 413-428.
Crossref
Crossref
HaoXiao Chang, YuZhen Wei, YuJing Chen, Li Du, HengRi Cong, XingHu Zhang, XingChao Geng & LinLin Yin. (2019) The antipsychotic-like effects of clozapine in C57BL/6 mice exposed to cuprizone: Decreased glial activation. Behavioural Brain Research 364, pages 157-161.
Crossref
Crossref
Tilman Steinert & Sophie Hirsch. 2019. S3-Leitlinie Verhinderung von Zwang: Prävention und Therapie aggressiven Verhaltens bei Erwachsenen. S3-Leitlinie Verhinderung von Zwang: Prävention und Therapie aggressiven Verhaltens bei Erwachsenen
95
152
.
Christopher RohdeChristoffer PolcwiartekChristoph U. CorrellJimmi Nielsen. (2018) Real-World Effectiveness of Clozapine for Borderline Personality Disorder: Results From a 2-Year Mirror-Image Study. Journal of Personality Disorders 32:6, pages 823-837.
Crossref
Crossref
Stefano Aringhieri, Marco Carli, Shivakumar Kolachalam, Valeria Verdesca, Enrico Cini, Mario Rossi, Peter J. McCormick, Giovanni U. Corsini, Roberto Maggio & Marco Scarselli. (2018) Molecular targets of atypical antipsychotics: From mechanism of action to clinical differences. Pharmacology & Therapeutics 192, pages 20-41.
Crossref
Crossref
Heeyoung Lee, Britney B. Scolieri & Prabir K. Mullick. (2018) Learned lessons from patients who take clozapine: A case study. Perspectives in Psychiatric Care 54:4, pages 457-461.
Crossref
Crossref
Yuh-Lin Gan & Claire L. O’Reilly. (2018) Community pharmacists’ attitudes and opinions towards supplying clozapine. International Journal of Clinical Pharmacy 40:5, pages 1116-1130.
Crossref
Crossref
Dılgeş Baskın, Yasin Çetinkaya & Metin Balci. (2018) Synthesis of dipyrrolo-diazepine derivatives via intramolecular alkyne cyclization. Tetrahedron 74:30, pages 4062-4070.
Crossref
Crossref
Veera M. Rajagopal, Anto P. Rajkumar, Kuruthukulangara S. Jacob & Molly Jacob. (2018) Gene–gene interaction between DRD4 and COMT modulates clinical response to clozapine in treatment-resistant schizophrenia. Pharmacogenetics and Genomics 28:1, pages 31-35.
Crossref
Crossref
Jibran Y. Khokhar, Angela M. Henricks, Emily D.K. Sullivan & Alan I. Green. 2018. Apprentices to Genius: A tribute to Solomon H. Snyder. Apprentices to Genius: A tribute to Solomon H. Snyder
137
162
.
Yusuke Nakata, Nobuhisa Kanahara & Masaomi Iyo. (2017) Dopamine supersensitivity psychosis in schizophrenia: Concepts and implications in clinical practice. Journal of Psychopharmacology 31:12, pages 1511-1518.
Crossref
Crossref
Mijeong Kang, Eunkyoung Kim, Thomas E. Winkler, George Banis, Yi Liu, Christopher A. Kitchen, Deanna L. Kelly, Reza Ghodssi & Gregory F. Payne. (2017) Reliable clinical serum analysis with reusable electrochemical sensor: Toward point-of-care measurement of the antipsychotic medication clozapine. Biosensors and Bioelectronics 95, pages 55-59.
Crossref
Crossref
Yusuke Nakata, Nobuhisa Kanahara, Hiroshi Kimura, Hiroyuki Watanabe & Masaomi Iyo. (2017) Efficacy of clozapine on dopamine supersensitivity psychosis in schizophrenia. International Clinical Psychopharmacology 32:3, pages 169-173.
Crossref
Crossref
Trevor HawkinsBrian D. Berman. (2017) Pimavanserin. Neurology Clinical Practice 7:2, pages 157-162.
Crossref
Crossref
R. Land, D. Siskind, P. McArdle, S. Kisely, K. Winckel & S. A. Hollingworth. (2017) The impact of clozapine on hospital use: a systematic review and meta-analysis. Acta Psychiatrica Scandinavica 135:4, pages 296-309.
Crossref
Crossref
Eunkyoung Kim, Yi Liu, Hadar Ben‐Yoav, Thomas E. Winkler, Kun Yan, Xiaowen Shi, Jana Shen, Deanna L. Kelly, Reza Ghodssi, William E. Bentley & Gregory F. Payne. (2016) Fusing Sensor Paradigms to Acquire Chemical Information: An Integrative Role for Smart Biopolymeric Hydrogels. Advanced Healthcare Materials 5:20, pages 2595-2616.
Crossref
Crossref
Simone M. Vieira, Luana R. Michels, Katiane Roversi, Vinícia G. Metz, Barbra K.S. Moraes, Eduarda M. Piegas, Rodrigo J. Freddo, André Gundel, Teresa Dalla Costa, Marilise E. Burger, Letícia M. Colomé & Sandra E. Haas. (2016) A surface modification of clozapine-loaded nanocapsules improves their efficacy: A study of formulation development and biological assessment. Colloids and Surfaces B: Biointerfaces 145, pages 748-756.
Crossref
Crossref
J.L. Padmanabhan & M.S. Keshavan. 2016. Encyclopedia of Mental Health. Encyclopedia of Mental Health
55
65
.
Emily J. Jaehne, Hayley Ramshaw, Xiangjun Xu, Eiman Saleh, Scott R. Clark, Klaus Oliver Schubert, Angel Lopez, Quenten Schwarz & Bernhard T. Baune. (2015) In-vivo administration of clozapine affects behaviour but does not reverse dendritic spine deficits in the 14-3-3ζ KO mouse model of schizophrenia-like disorders. Pharmacology Biochemistry and Behavior 138, pages 1-8.
Crossref
Crossref
Mei-Ling Hou, Chi-Hung Lin, Lie-Chwen Lin & Tung-Hu Tsai. (2015) The Drug-Drug Effects of Rhein on the Pharmacokinetics and Pharmacodynamics of Clozapine in Rat Brain Extracellular Fluid by In Vivo Microdialysis. Journal of Pharmacology and Experimental Therapeutics 355:1, pages 125-134.
Crossref
Crossref
K. J. Ronaldson, P. B. Fitzgerald & J. J. McNeil. (2015) Clozapine‐induced myocarditis, a widely overlooked adverse reaction. Acta Psychiatrica Scandinavica 132:4, pages 231-240.
Crossref
Crossref
Ornella Manfra, Kathleen Van Craenenbroeck, Kamila Skieterska, Thomas Frimurer, Thue W. Schwartz, Finn Olav Levy & Kjetil Wessel Andressen. (2015)
Downregulation of 5-HT
7
Serotonin Receptors by the Atypical Antipsychotics Clozapine and Olanzapine. Role of Motifs in the C-Terminal Domain and Interaction with GASP-1
. ACS Chemical Neuroscience 6:7, pages 1206-1218.
Crossref
Crossref
Andreas Hartmann, Steven Whitebread, Jacques Hamon, Alexander Fekete, Christian Trendelenburg, Patrick Y. Müller & László Urbán. 2015. Antitargets and Drug Safety. Antitargets and Drug Safety
457
478
.
Eunkyoung Kim, Sheryl E. Chocron, Hadar Ben-Yoav, Thomas E. Winkler, Yi Liu, Matthew Glassman, Christopher Wolfram, Deanna L. Kelly, Reza Ghodssi & Gregory F. Payne. (2015) Programmable “Semismart” Sensor: Relevance to Monitoring Antipsychotics. Advanced Functional Materials 25:14, pages 2156-2165.
Crossref
Crossref
Darcy Brown, Fintan Larkin, Samrat Sengupta, Jose L. Romero-Ureclay, Callum C. Ross, Nitin Gupta, Morris Vinestock & Mrigendra Das. (2014) Clozapine: an effective treatment for seriously violent and psychopathic men with antisocial personality disorder in a UK high-security hospital. CNS Spectrums 19:5, pages 391-402.
Crossref
Crossref
James E. Hotham, Patrick J. D. Simpson, Rosalie S. Brooman-White, Amlan Basu, Callum C. Ross, Sharon A. Humphreys, Fintan Larkin, Nitin Gupta & Mrigendra Das. (2013) Augmentation of clozapine with amisulpride: an effective therapeutic strategy for violent treatment-resistant schizophrenia patients in a UK high-security hospital. CNS Spectrums 19:5, pages 403-410.
Crossref
Crossref
Stefan Schmidinger & Alex Hofer. (2014) Pulmonary Embolism and Aspiration Pneumonia After Reexposure to Clozapine. Journal of Clinical Psychopharmacology 34:3, pages 385-387.
Crossref
Crossref
Katherine A. Lyseng-Williamson. (2014) Clozapine oral suspension (Versacloz™): a guide to its use in the USA. Drugs & Therapy Perspectives 30:6, pages 193-199.
Crossref
Crossref
Hiroshi Kimura, Nobuhisa Kanahara, Naoya Komatsu, Minoru Ishige, Katsumasa Muneoka, Masayuki Yoshimura, Hiroshi Yamanaka, Tomotaka Suzuki, Hideki Komatsu, Tsuyoshi Sasaki, Tasuku Hashimoto, Tadashi Hasegawa, Akihiro Shiina, Masatomo Ishikawa, Yoshimoto Sekine, Tetsuya Shiraishi, Hiroyuki Watanabe, Eiji Shimizu, Kenji Hashimoto & Masaomi Iyo. (2014) A prospective comparative study of risperidone long-acting injectable for treatment-resistant schizophrenia with dopamine supersensitivity psychosis. Schizophrenia Research 155:1-3, pages 52-58.
Crossref
Crossref
Peng Li, Qiang Zhang, Albert J. Robichaud, Taekyu Lee, John Tomesch, Wei Yao, J. David Beard, Gretchen L. Snyder, Hongwen Zhu, Youyi Peng, Joseph P. Hendrick, Kimberly E. Vanover, Robert E. Davis, Sharon Mates & Lawrence P. Wennogle. (2014) Discovery of a Tetracyclic Quinoxaline Derivative as a Potent and Orally Active Multifunctional Drug Candidate for the Treatment of Neuropsychiatric and Neurological Disorders. Journal of Medicinal Chemistry 57:6, pages 2670-2682.
Crossref
Crossref
Nuwan C. Hettige, James L. Kennedy & Vincenzo De Luca. (2014) Does a history of suicide attempt predict higher antipsychotic dosage in schizophrenia?. Psychopharmacology.
Crossref
Crossref
Pierre Chue & Bogdan Neagu. 2014. A worldwide yearly survey of new data in adverse drug reactions. A worldwide yearly survey of new data in adverse drug reactions
59
84
.
Philip G. Janicak. 2014. Schizophrenia. Schizophrenia
107
138
.
Wanlop Atsariyasing & Morris Goldman. 2014. Schizophrenia. Schizophrenia
225
262
.
Tara Donker, Alison Calear, Janie Busby Grant, Bregje van Spijker, Katherine Fenton, Kanupriya Kalia Hehir, Pim Cuijpers & Helen Christensen. (2013) Suicide prevention in schizophrenia spectrum disorders and psychosis: a systematic review. BMC Psychology 1:1.
Crossref
Crossref
Nandita Hazari, Natasha Kate & Sandeep Grover. (2013) Clozapine and tardive movement disorders: A review. Asian Journal of Psychiatry 6:6, pages 439-451.
Crossref
Crossref
Cody J. Wenthur & Craig W. Lindsley. (2013) Classics in Chemical Neuroscience: Clozapine. ACS Chemical Neuroscience 4:7, pages 1018-1025.
Crossref
Crossref
Katherine A. Lyseng-Williamson. (2013) Clozapine: a guide to its use in patients with schizophrenia who are unresponsive to or intolerant of other antipsychotic agents. Drugs & Therapy Perspectives 29:6, pages 161-165.
Crossref
Crossref
Vivek Bambole, Nilesh Shah, Shushma Sonavane, Megan Johnston & Amresh Shrivastava. (2013) Study of negatives symptoms in first episode schizophrenia. Open Journal of Psychiatry 03:03, pages 323-328.
Crossref
Crossref
Roland Seifert, Andrea Strasser, Erich H. Schneider, Detlef Neumann, Stefan Dove & Armin Buschauer. (2013) Molecular and cellular analysis of human histamine receptor subtypes. Trends in Pharmacological Sciences 34:1, pages 33-58.
Crossref
Crossref
Andrea de Bartolomeis, Licia Vellucci, Annarita Barone, Mirko Manchia, Vincenzo De Luca, Felice Iasevoli & Christoph Correll. (2022) Clozapine's Multiple Cellular Mechanisms: What Do We Know after More than Fifty Years? a Systematic Review and Critical Assessment of Translational Mechanisms Relevant for Innovative Strategies in Treatment-Resistant Schizophrenia. SSRN Electronic Journal.
Crossref
Crossref