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Drug Evaluations

A 10-year perspective on donepezil

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Pages 331-338 | Published online: 14 Jan 2013

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Sirasa Ruangritchankul, Prawat Chantharit, Sahaphume Srisuma & Leonard C Gray. (2021) Adverse Drug Reactions of Acetylcholinesterase Inhibitors in Older People Living with Dementia: A Comprehensive Literature Review. Therapeutics and Clinical Risk Management 17, pages 927-949.
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Articles from other publishers (33)

Poonè Haghani Tehrani, Kanchan K. Kohli & Mohamad H. Khafaja. (2021) Donepezil and Inappropriate Sexual Behavior in a Patient With Vascular Dementia and on Bupropion. Journal of Clinical Psychopharmacology 41:6, pages 696-698.
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Miroslav Pohanka. (2021) Pharmacological Influencing of The Cholinergic Anti-inflammatory Pathway in Infectious Diseases and Inflammatory Pathologies. Mini-Reviews in Medicinal Chemistry 21:6, pages 660-669.
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Yingda Zang, Ke Liu, Weiping Wang, Chuangjun Li, Jie Ma, Jingzhi Yang, Xinyi Chen, Xiaoliang Wang & Dongming Zhang. (2021) Claulansine F–Donepezil Hybrids as Anti-Alzheimer’s Disease Agents with Cholinergic, Free-Radical Scavenging, and Neuroprotective Activities. Molecules 26:5, pages 1303.
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Miroslav Pohanka. (2020) Inhibitors of Cholinesterases in Pharmacology: the Current Trends. Mini-Reviews in Medicinal Chemistry 20:15, pages 1532-1542.
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Belgin Sever, Mehlika Dilek Altıntop & Halide Edip Temel. (2020) In vitro and in silico studies on AChE inhibitory effects of a series of donepezil-like arylidene indanones . Turkish Journal of Biochemistry 45:4, pages 359-363.
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Miroslav Pohanka. (2020) Diagnoses of Pathological States Based on Acetylcholinesterase and Butyrylcholinesterase. Current Medicinal Chemistry 27:18, pages 2994-3011.
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Mehlika Dilek Altıntop. (2020) Synthesis, In vitro and In silico Evaluation of a Series of Pyrazolines as New Anticholinesterase Agents. Letters in Drug Design & Discovery 17:5, pages 574-584.
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Hulya Akıncıoğlu & İlhami Gülçin. (2020) Potent Acetylcholinesterase Inhibitors: Potential Drugs for Alzheimer’s Disease. Mini-Reviews in Medicinal Chemistry 20:8, pages 703-715.
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Valery M. Dembitsky, Lilya Dzhemileva, Tatyana Gloriozova & Vladimir D’yakonov. (2020) Natural and synthetic drugs used for the treatment of the dementia. Biochemical and Biophysical Research Communications 524:3, pages 772-783.
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Keshireddy AnjiReddy & Subramanian Karpagam. (2020) Micro and nanocrystalline cellulose based oral dispersible film; preparation and evaluation of in vitro/in vivo rapid release studies for donepezil. Brazilian Journal of Pharmaceutical Sciences 56.
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Atukuri Dorababu. (2019) Critical evaluation of current Alzheimer’s drug discovery (2018–19) & futuristic Alzheimer drug model approach. Bioorganic Chemistry 93, pages 103299.
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Malose J. Mphahlele, Samantha Gildenhuys & Emmanuel N. Agbo. (2019) In Vitro Evaluation and Docking Studies of 5-oxo-5H-furo[3,2-g]chromene-6-carbaldehyde Derivatives as Potential Anti-Alzheimer’s Agents. International Journal of Molecular Sciences 20:21, pages 5451.
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Martina Kaniakova, Eugenie Nepovimova, Lenka Kleteckova, Kristyna Skrenkova, Kristina Holubova, Zofia Chrienova, Vendula Hepnarova, Tomas Kucera, Tereza Kobrlova, Karel Vales, Jan Korabecny, Ondrej Soukup & Martin Horak. (2019) Combination of Memantine and 6-Chlorotacrine as Novel Multi-Target Compound against Alzheimer’s Disease. Current Alzheimer Research 16:9, pages 821-833.
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Jan Korabecny, Katarina Spilovska, Eva Mezeiova, Ondrej Benek, Radomir Juza, Daniel Kaping & Ondrej Soukup. (2019) A Systematic Review on Donepezil-based Derivatives as Potential Cholinesterase Inhibitors for Alzheimer’s Disease. Current Medicinal Chemistry 26:30, pages 5625-5648.
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Yorley Duarte, Margarita Gutierrez, Rocío Álvarez, Jans H. Alzate‐Morales & Jorge Soto‐Delgado. (2019) Experimental and Theoretical Approaches in the Study of Phenanthroline‐Tetrahydroquinolines for Alzheimer's Disease. ChemistryOpen 8:5, pages 627-636.
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Jing Jiang, Gang Liu, Suhua Shi, Yujie Li & Zhigang Li. (2019) Effects of manual acupuncture combined with donepezil in a mouse model of Alzheimer’s disease. Acupuncture in Medicine 37:1, pages 64-71.
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Marta Goschorska, Izabela Gutowska, Irena Baranowska-Bosiacka, Katarzyna Piotrowska, Emilia Metryka, Krzysztof Safranow & Dariusz Chlubek. (2018) Influence of Acetylcholinesterase Inhibitors Used in Alzheimer’s Disease Treatment on the Activity of Antioxidant Enzymes and the Concentration of Glutathione in THP-1 Macrophages under Fluoride-Induced Oxidative Stress. International Journal of Environmental Research and Public Health 16:1, pages 10.
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Pei Cai, Si-Qiang Fang, Hua-Li Yang, Xue-Lian Yang, Qiao-Hong Liu, Ling-Yi Kong & Xiao-Bing Wang. (2018) Donepezil-butylated hydroxytoluene (BHT) hybrids as Anti-Alzheimer's disease agents with cholinergic, antioxidant, and neuroprotective properties. European Journal of Medicinal Chemistry 157, pages 161-176.
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Marta Goschorska, Irena Baranowska-Bosiacka, Izabela Gutowska, Maciej Tarnowski, Katarzyna Piotrowska, Emilia Metryka, Krzysztof Safranow & Dariusz Chlubek. (2018) Effect of acetylcholinesterase inhibitors donepezil and rivastigmine on the activity and expression of cyclooxygenases in a model of the inflammatory action of fluoride on macrophages obtained from THP-1 monocytes. Toxicology 406-407, pages 9-20.
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Jana Zdarova Karasova, Vit Sestak, Jan Korabecny, Eva Mezeiova, Vladimir Palicka, Kamil Kuca & Martin Mzik. (2018) 1-Benzyl-4-methylpiperidinyl moiety in donepezil: The priority ticket across the blood-brain-barrier in rats. Journal of Chromatography B 1092, pages 350-358.
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Vinod Kaushik, Sarah Toombs Smith, Emmanuel Mikobi & Mukaila A. Raji. (2017) Acetylcholinesterase Inhibitors: Beneficial Effects on Comorbidities in Patients With Alzheimer’s Disease. American Journal of Alzheimer's Disease & Other Dementiasr 33:2, pages 73-85.
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Olga Karoutzou, Seung-Hwa Kwak, So-Deok Lee, Daina Martínez-Falguera, Francesc Sureda, Santiago Vázquez, Yong-Chul Kim & Marta Barniol-Xicota. (2018) Towards a Novel Class of Multitarget-Directed Ligands: Dual P2X7–NMDA Receptor Antagonists. Molecules 23:1, pages 230.
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Keshireddy Anji Reddy & S. Karpagam. (2017) Cellulose Orodispersible Films of Donepezil: Film Characterization and Drug Release. Pharmaceutical Chemistry Journal 51:8, pages 707-715.
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Miroslav Pohanka. (2016) Electrochemical Biosensors based on Acetylcholinesterase and Butyrylcholinesterase. A Review. International Journal of Electrochemical Science 11:9, pages 7440-7452.
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Ruben Vardanyan & Victor Hruby. 2016. Synthesis of Best-Seller Drugs. Synthesis of Best-Seller Drugs 215 225 .
Jadna Bogado Lopes, Jade de Oliveira, Daiane Fátima Engel, Gabriela Cristina de Paula, Eduardo Luiz Gasnhar Moreira & Andreza Fabro de Bem. (2015) Efficacy of Donepezil for Cognitive Impairments in Familial Hypercholesterolemia: Preclinical Proof of Concept. CNS Neuroscience & Therapeutics 21:12, pages 964-966.
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Roberta Farina, Leonardo Pisani, Marco Catto, Orazio Nicolotti, Domenico Gadaleta, Nunzio Denora, Ramon Soto-Otero, Estefania Mendez-Alvarez, Carolina S. Passos, Giovanni Muncipinto, Cosimo D. Altomare, Alessandra Nurisso, Pierre-Alain Carrupt & Angelo Carotti. (2015) Structure-Based Design and Optimization of Multitarget-Directed 2 H -Chromen-2-one Derivatives as Potent Inhibitors of Monoamine Oxidase B and Cholinesterases . Journal of Medicinal Chemistry 58:14, pages 5561-5578.
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Sayaka Nagasawa, Suguru Torimitsu, Fumiko Chiba, Yuko Kubo, Daisuke Yajima & Hirotaro Iwase. (2015) Donepezil distribution in postmortem cases and potential for redistribution. Forensic Science International 251, pages 132-138.
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Lawrence Kleinberg. (2015) Neurocognitive Challenges in Brain Tumor Survivors: Is There Anything We Can Do?. Journal of Clinical Oncology 33:15, pages 1633-1636.
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Miroslav Pohanka. (2015) Biosensors containing acetylcholinesterase and butyrylcholinesterase as recognition tools for detection of various compounds. Chemical Papers 69:1.
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Yvonne Boyle, Disala Fernando, Hazel Kurz, Sam R. Miller, Mauro Zucchetto & James Storey. (2014) The effect of a combination of gabapentin and donepezil in an experimental pain model in healthy volunteers: Results of a randomized controlled trial. Pain 155:12, pages 2510-2516.
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Miroslav Pohanka. (2014) Inhibitors of Acetylcholinesterase and Butyrylcholinesterase Meet Immunity. International Journal of Molecular Sciences 15:6, pages 9809-9825.
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Ornella Di Pietro, Elisabet Viayna, Esther Vicente-García, Manuela Bartolini, Rosario Ramón, Jordi Juárez-Jiménez, M. Victòria Clos, Belén Pérez, Vincenza Andrisano, F. Javier Luque, Rodolfo Lavilla & Diego Muñoz-Torrero. (2014) 1,2,3,4-Tetrahydrobenzo[h][1,6]naphthyridines as a new family of potent peripheral-to-midgorge-site inhibitors of acetylcholinesterase: Synthesis, pharmacological evaluation and mechanistic studies. European Journal of Medicinal Chemistry 73, pages 141-152.
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