748
Views
45
CrossRef citations to date
0
Altmetric
Drug Evaluations

The use of raloxifene in osteoporosis treatment

, MD PhD & , MD
Pages 949-956 | Published online: 24 Mar 2013

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (2)

Andrea Luque-Bolivar, Erika Pérez-Mora, Victoria Eugenia Villegas & Milena Rondón-Lagos. (2020) Resistance and Overcoming Resistance in Breast Cancer. Breast Cancer: Targets and Therapy 12, pages 211-229.
Read now
Naoki Kishi, Akane Takasuka, Yuki Kokawa, Takashi Isobe, Maho Taguchi, Masato Shigeyama, Mikio Murata, Manabu Suno & Nobumitsu Hanioka. (2016) Raloxifene glucuronidation in liver and intestinal microsomes of humans and monkeys: contribution of UGT1A1, UGT1A8 and UGT1A9. Xenobiotica 46:4, pages 289-295.
Read now

Articles from other publishers (43)

Haoran Wang, Ji Wu, Boyao Wang, Hu Qin, Lei Fan, Yunhua Wang & Bin He. (2023) Progress in Prevention and Treatment of Acute Bone Loss in Orthopedics. International Journal of Endocrinology 2023, pages 1-10.
Crossref
Zhenfeng Song, Kuang-Wei Wang, Hsiao-Tien Chien Hagar, Hong-Ru Chen, Chia-Yi Kuan, Kezhong Zhang & Min-Hao Kuo. (2023) Hyperphosphorylated Tau Inflicts Intracellular Stress Responses that Are Mitigated by Apomorphine. Molecular Neurobiology.
Crossref
Ivan V. Zhivodernikov, Tatiana V. Kirichenko, Yuliya V. Markina, Anton Y. Postnov & Alexander M. Markin. (2023) Molecular and Cellular Mechanisms of Osteoporosis. International Journal of Molecular Sciences 24:21, pages 15772.
Crossref
Dong Wu, Lei Li, Zhun Wen & Guangbin Wang. (2023) Romosozumab in osteoporosis: yesterday, today and tomorrow. Journal of Translational Medicine 21:1.
Crossref
Ning Dong, Yongli Du, Yong Zheng, Haibin Zhang, Huiting Lv & Zhijia Yan. (2023) Research progress on tamoxifen and its analogs associated with nuclear receptors. Future Medicinal Chemistry.
Crossref
Ryan J Schroeder, Julia Staszkiewicz, Collyn O'Quin, Brandon Carroll, Nicolette Doan, Sagar Patel, Shahab Ahmadzadeh, Anusha Kallurkar, Omar Viswanath, Giustino Varrassi, Sahar Shekoohi & Alan D Kaye. (2023) Oral Therapeutics Post Menopausal Osteoporosis. Cureus.
Crossref
Parul Grover, Suman Rohilla, Monika Bhardwaj, Lovekesh Mehta & Anjleena Malhotra. (2023) Piperidine Nucleus as a Promising Scaffold for Alzheimer’s Disease: Current Landscape and Future Perspective. Current Topics in Medicinal Chemistry 23:13, pages 1221-1259.
Crossref
Manaswini Ghosh & Soumendra Rana. (2023) The anaphylatoxin C5a: Structure, function, signaling, physiology, disease, and therapeutics. International Immunopharmacology 118, pages 110081.
Crossref
Ting-Chun Liu, Chien-Ning Hsu, Wen-Chin Lee, Shih-Wei Wang, Chiang-Chi Huang, Yueh-Ting Lee, Chung-Ming Fu, Jin-Bor Chen & Lung-Chih Li. (2023) Denosumab Is Superior to Raloxifene in Lowering Risks of Mortality and Ischemic Stroke in Osteoporotic Women. Pharmaceuticals 16:2, pages 222.
Crossref
Grace Clouse, Samantha Penman, Michael Hadjiargyrou, David E. Komatsu & Panayotis K. Thanos. (2022) Examining the role of cannabinoids on osteoporosis: a review. Archives of Osteoporosis 17:1.
Crossref
Manqi Gao, Zhongkai Zhang, Jiabin Sun, Bo Li & Yuan Li. (2022) The roles of circRNA–miRNA–mRNA networks in the development and treatment of osteoporosis. Frontiers in Endocrinology 13.
Crossref
Hongye Zou, Yatian Yang, Zhenrui Shi, Xuesong Wu, Ruiwu Liu, Ai-Ming Yu & Hong-Wu Chen. (2022) Nuclear receptor RORγ inverse agonists/antagonists display tissue- and gene-context selectivity through distinct activities in altering chromatin accessibility and master regulator SREBP2 occupancy. Pharmacological Research 182, pages 106324.
Crossref
Hsin-Wei Chen, Chien-Ning Hsu, Yueh-Ting Lee, Chung-Ming Fu, Shih-Wei Wang, Chiang-Chi Huang & Lung-Chih Li. (2022) Comparative Adverse Kidney Outcomes in Women Receiving Raloxifene and Denosumab in a Real-World Setting. Biomedicines 10:7, pages 1494.
Crossref
Angélica Villanueva-Martínez, Virginia Merino & Adriana Ganem-Rondero. (2022) Transdermal formulations and strategies for the treatment of osteoporosis. Journal of Drug Delivery Science and Technology 69, pages 103111.
Crossref
Jinuk Jung, Hyunwhan JoeKyungsik HaJin-muk LimHong-gee Kim. (2021) Biomedical Entity Explorer: A Web Server for Biomedical Entity Exploration. Journal of Computational Biology 28:6, pages 619-628.
Crossref
Rachel Fritz, Linda Edwards & Rafik Jacob. (2021) Osteoporosis in Adult Patients with Intellectual and Developmental Disabilities: Special Considerations for Diagnosis, Prevention, and Management. Southern Medical Journal 114:4, pages 246-251.
Crossref
Francesca Salamanna, Alessandro Gambardella, Deyanira Contartese, Andrea Visani & Milena Fini. (2021) Nano-Based Biomaterials as Drug Delivery Systems Against Osteoporosis: A Systematic Review of Preclinical and Clinical Evidence. Nanomaterials 11:2, pages 530.
Crossref
Aditi Khatpe, Adedeji Adebayo, Christopher Herodotou, Brijesh Kumar & Harikrishna Nakshatri. (2021) Nexus between PI3K/AKT and Estrogen Receptor Signaling in Breast Cancer. Cancers 13:3, pages 369.
Crossref
Mengyu Liu, Thomas Dexheimer, Dexin Sui, Stacy Hovde, Xiexiong Deng, Roland Kwok, Daniel A. Bochar & Min-Hao Kuo. (2020) Hyperphosphorylated tau aggregation and cytotoxicity modulators screen identified prescription drugs linked to Alzheimer's disease and cognitive functions. Scientific Reports 10:1.
Crossref
Bárbara Costa, Irina Amorim, Fátima Gärtner & Nuno Vale. (2020) Understanding Breast cancer: from conventional therapies to repurposed drugs. European Journal of Pharmaceutical Sciences 151, pages 105401.
Crossref
Denise Börzsei, Renáta Szabó, Alexandra Hoffmann, Médea Veszelka, Imre Pávó, Zsolt Turcsán, Csaba Viczián, Krisztina Kupai, Csaba Varga & Anikó Pósa. (2020) Distinct Approaches of Raloxifene: Its Far-Reaching Beneficial Effects Implicating the HO-System. Biomolecules 10:3, pages 375.
Crossref
Miguel Gisbert-Garzarán, Miguel Manzano & María Vallet-Regí. (2020) Mesoporous Silica Nanoparticles for the Treatment of Complex Bone Diseases: Bone Cancer, Bone Infection and Osteoporosis. Pharmaceutics 12:1, pages 83.
Crossref
Aakriti Garg, Balraj Singh, Ruchika Sharma, Arti Singh & Anoop Kumar. (2020) Selective Estrogen Receptor Modulators (SERMs): Mechanistic Insights Against Microbial Infections. Current Molecular Medicine 20:2, pages 102-115.
Crossref
Mariela AgotegarayMariela Agotegaray. 2020. Silica-Based Nanotechnology for Bone Disease Treatment. Silica-Based Nanotechnology for Bone Disease Treatment 25 38 .
Tanmay Saha, Subhajit Makar, Rayala Swetha, Gopichand Gutti & Sushil K. Singh. (2019) Estrogen signaling: An emanating therapeutic target for breast cancer treatment. European Journal of Medicinal Chemistry 177, pages 116-143.
Crossref
Yukitomo Arao & Kenneth S. Korach. (2019) Transactivation Function-1-Mediated Partial Agonist Activity of Selective Estrogen Receptor Modulator Requires Homo-Dimerization of the Estrogen Receptor α Ligand Binding Domain. International Journal of Molecular Sciences 20:15, pages 3718.
Crossref
Vasilis Paspaliaris & George Kolios. (2019) Stem cells in Osteoporosis: From Biology to New Therapeutic Approaches. Stem Cells International 2019, pages 1-16.
Crossref
Huanhuan Xu, Titi Liu, Lihong Hu, Jin Li, Chunxia Gan, Jing Xu, Fei Chen, Zemin Xiang, Xuanjun Wang & Jun Sheng. (2019) Effect of caffeine on ovariectomy-induced osteoporosis in rats. Biomedicine & Pharmacotherapy 112, pages 108650.
Crossref
Marie-Cécile Valéra, Coralie Fontaine, Emmanuelle Noirrit-Esclassan, Frédéric Boudou, Melissa Buscato, Marine Adlanmerini, Florence Trémollières, Pierre Gourdy, Françoise Lenfant & Jean-François Arnal. (2019) Vers une optimisation de la modulation du récepteur des œstrogènes dans le traitement hormonal de la ménopause. médecine/sciences 34:12, pages 1056-1062.
Crossref
Thomas Sorenson, Jane M. Korducki & Charles R. Watts. (2018) Comprehensive Management of Osteoporotic Thoracic and Lumbar Vertebral Compression Fractures. Contemporary Neurosurgery 40:16, pages 1-7.
Crossref
Titi Liu, Zemin Xiang, Fei Chen, Dan Yin, Yewei Huang, Jing Xu, Lihong Hu, Huanhuan Xu, Xuanjun Wang & Jun Sheng. (2018) Theabrownin suppresses in vitro osteoclastogenesis and prevents bone loss in ovariectomized rats. Biomedicine & Pharmacotherapy 106, pages 1339-1347.
Crossref
Marie-Cécile Valéra, Coralie Fontaine, Marion Dupuis, Emmanuelle Noirrit-Esclassan, Alexia Vinel, Maeva Guillaume, Pierre Gourdy, Françoise Lenfant & Jean-François Arnal. (2018) Towards optimization of estrogen receptor modulation in medicine. Pharmacology & Therapeutics 189, pages 123-129.
Crossref
Xiao-Min Zhu, Wei Zheng, Xiao-Hong Li, Dong-Bin Cai, Xin-Hu Yang, Gabor S. Ungvari, Chee H. Ng, Xiao-Ping Wang, Jayashri Kulkarni, Jasmin Grigg, Yu-Ping Ning & Yu-Tao Xiang. (2018) Adjunctive raloxifene for postmenopausal women with schizophrenia: A meta-analysis of randomized, double-blind, placebo-controlled trials. Schizophrenia Research 197, pages 288-293.
Crossref
Meihua Han, Xiaoyu Qi, Dongdong Bi, Yijing Li, Yifei Guo, Xiangtao Wang & Li Feng. (2018) Administration of raloxifene hydrochloride nanosuspensions partially attenuates bone loss in ovariectomized mice. RSC Advances 8:42, pages 23748-23756.
Crossref
Allan Peter Davis, Thomas C. Wiegers, Benjamin L. King, Jolene Wiegers, Cynthia J. Grondin, Daniela Sciaky, Robin J. Johnson & Carolyn J. Mattingly. (2016) Generating Gene Ontology-Disease Inferences to Explore Mechanisms of Human Disease at the Comparative Toxicogenomics Database. PLOS ONE 11:5, pages e0155530.
Crossref
Xiaotong Zhou, Shaoxiang Wang, Hua Sun & Baojian Wu. (2015) Sulfonation of raloxifene in HEK293 cells overexpressing SULT1A3: Involvement of breast cancer resistance protein (BCRP/ABCG2) and multidrug resistance-associated protein 4 (MRP4/ABCC4) in excretion of sulfate metabolites. Drug Metabolism and Pharmacokinetics 30:6, pages 425-433.
Crossref
Aekkapot Chamkasem & Waraphan Toniti. (2015) Sequence to Structure Approach of Estrogen Receptor Alpha and Ligand Interactions. Asian Pacific Journal of Cancer Prevention 16:6, pages 2161-2166.
Crossref
Ramesh Narayanan & James T. Dalton. 2015. Nuclear Receptors: From Structure to the Clinic. Nuclear Receptors: From Structure to the Clinic 205 227 .
Yubo Guo, Yu Li, Liming Xue, Richele P. Severino, Sihua Gao, Jianzhao Niu, Lu-Ping Qin, Dongwei Zhang & Dieter Brömme. (2014) Salvia miltiorrhiza: An ancient Chinese herbal medicine as a source for anti-osteoporotic drugs. Journal of Ethnopharmacology 155:3, pages 1401-1416.
Crossref
Pratap Karki, Anton Webb, Abdelbassat Zerguine, Joseph Choi, Deok-Soo Son & Eunsook Lee. (2014) Mechanism of raloxifene-induced upregulation of glutamate transporters in rat primary astrocytes. Glia 62:8, pages 1270-1283.
Crossref
Judee Grace E. Nemeno, Soojung Lee, Wojong Yang, Kyung Mi Lee & Jeong Ik Lee. (2014) Applications and Implications of Heparin and Protamine in Tissue Engineering and Regenerative Medicine. BioMed Research International 2014, pages 1-10.
Crossref
Loomee Doo & Charles L. Shapiro. (2013) Skeletal Manifestations of Treatment of Breast Cancer on Premenopausal Women. Current Osteoporosis Reports 11:4, pages 311-318.
Crossref
Koch Visser, Morné Mortimer & Ann Louw. (2013) Cyclopia Extracts Act as ERα Antagonists and ERβ Agonists, In Vitro and In Vivo. PLoS ONE 8:11, pages e79223.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.