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Current pharmacological treatment approaches for alcohol dependence

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Gabriel C Quintero Garzola. (2020) The Use of Gabapentin for the Treatment of Alcohol and Tobacco Use Disorders: A Review. Open Access Journal of Clinical Trials 12, pages 43-60.
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Michael Soyka & Christian A. Müller. (2017) Pharmacotherapy of alcoholism – an update on approved and off-label medications. Expert Opinion on Pharmacotherapy 18:12, pages 1187-1199.
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Michael Soyka, Henry R. Kranzler, Victor Hesselbrock, Siegfried Kasper, Jochen Mutschler & Hans-Jürgen Möller. (2017) Guidelines for biological treatment of substance use and related disorders, part 1: Alcoholism, first revision. The World Journal of Biological Psychiatry 18:2, pages 86-119.
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Michael Soyka. (2016) Nalmefene for the treatment of alcohol use disorders: recent data and clinical potential. Expert Opinion on Pharmacotherapy 17:4, pages 619-626.
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Jonathan Tomas Lockwood & Gary Remington. (2015) Emerging drugs for antipsychotic-induced tardive dyskinesia: investigational drugs in Phase II and Phase III clinical trials. Expert Opinion on Emerging Drugs 20:3, pages 407-421.
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Articles from other publishers (49)

Stefan Gutwinski & Andreas Heinz. 2023. Psychoneuroscience. Psychoneuroscience 243 261 .
Josephin Wagner, Andrew S. Bell, Jeesun Jung & Falk W. Lohoff. 2023. Alcohol and Alcohol-related Diseases. Alcohol and Alcohol-related Diseases 595 621 .
Pascal Valentin Fischler, Michael Soyka, Erich Seifritz & Jochen Mutschler. (2022) Off-label and investigational drugs in the treatment of alcohol use disorder: A critical review. Frontiers in Pharmacology 13.
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Falk W. Lohoff. (2022) Targeting Unmet Clinical Needs in the Treatment of Alcohol Use Disorder. Frontiers in Psychiatry 13.
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Aurélia Gay, Julien Cabe, Ingrid De Chazeron, Céline Lambert, Maxime Defour, Vikesh Bhoowabul, Thomas Charpeaud, Aurore Tremey, Pierre-Michel Llorca, Bruno Pereira & Georges Brousse. (2022) Repetitive Transcranial Magnetic Stimulation (rTMS) as a Promising Treatment for Craving in Stimulant Drugs and Behavioral Addiction: A Meta-Analysis. Journal of Clinical Medicine 11:3, pages 624.
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Chiara Montemitro, Alexandra Angebrandt, Tzu-Yun Wang, Mauro Pettorruso & Osama A. Abulseoud. (2021) Mechanistic insights into the efficacy of memantine in treating certain drug addictions. Progress in Neuro-Psychopharmacology and Biological Psychiatry 111, pages 110409.
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Falk W Lohoff. (2020) Pharmacotherapies and personalized medicine for alcohol use disorder: a review. Pharmacogenomics 21:15, pages 1117-1138.
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Sylvie Blairy & Emmanuel Pinto. 2020. L'alcool en questions. L'alcool en questions 127 137 .
Stefan Gutwinski & Andreas Heinz. 2020. Psychoneurowissenschaften. Psychoneurowissenschaften 255 273 .
Philippe Pfeifer & Christoph Fehr. (2019) Efficacy of Varenicline in Patients With Severe Alcohol Dependence. Journal of Clinical Psychopharmacology 39:4, pages 398-402.
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John C. Umhau. (2019) Conquering the Craving. Journal of Christian Nursing 36:3, pages 148-156.
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Thitiporn Supasitthumrong, Blanca M. Bolea‐Alamanac, Selim Asmer, Vincent L. Woo, Petal S. Abdool & Simon J.C. Davies. (2019) Gabapentin and pregabalin to treat aggressivity in dementia: a systematic review and illustrative case report. British Journal of Clinical Pharmacology 85:4, pages 690-703.
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Eduardo Costa Pinto, Chengdong Xu, Lucio Mendes Cabral, Daniel W. Armstrong & Valéria Pereira de Sousa. (2018) Sensitive detection of topiramate degradation products by high‐performance liquid chromatography/electrospray ionization mass spectrometry using ion‐pairing reagents and polarity switching. Rapid Communications in Mass Spectrometry 33:1, pages 116-124.
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Chidera C. Chukwueke & Bernard Le Foll. 2019. Psychiatric Disorders. Psychiatric Disorders 195 219 .
Yan Zhou & Mary Jeanne Kreek. (2018) Involvement of Activated Brain Stress Responsive Systems in Excessive and “Relapse” Alcohol Drinking in Rodent Models: Implications for Therapeutics. Journal of Pharmacology and Experimental Therapeutics 366:1, pages 9-20.
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SY Issa, EM Hafez, AS El-Banna, SM Abdel Rahman, MK AlMazroua & MA El-Hamd. (2017) Baclofen systemic toxicity: Experimental histopathological and biochemical study. Human & Experimental Toxicology 37:4, pages 431-441.
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José Benítez, David García, Nicol Romero, Arlette González, José Martínez-Oyanedel, Maximiliano Figueroa, Mónica Salas, Vasthi López, Peter R. Dodd, Gerhard Schenk, Nelson Carvajal & Elena Uribe. (2018) Metabolic strategies for the degradation of the neuromodulator agmatine in mammals. Metabolism 81, pages 35-44.
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Eduardo Costa Pinto, Mariana da Silva Gonçalves, Lucio Mendes Cabral, Daniel W. Armstrong & Valéria Pereira de Sousa. (2018) Development and validation of a stability-indicating HPLC method for topiramate using a mixed-mode column and charged aerosol detector. Journal of Separation Science 41:8, pages 1716-1725.
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Abhishek Ghosh & Siddharth Sarkar. (2018) Current legislation governing the care of individuals with substance use disorders in India: Rationale and implications. Indian Journal of Social Psychiatry 34:3, pages 189.
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Michael T. Bowen & Inga D. Neumann. (2017) Rebalancing the Addicted Brain: Oxytocin Interference with the Neural Substrates of Addiction. Trends in Neurosciences 40:12, pages 691-708.
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David Boels, Caroline Victorri‐Vigneau, Marie Grall‐Bronnec, Ali Touré, Anais Garnier, Alain Turcant & Gaël Le Roux. (2017) Baclofen and Alcohol‐Dependent Patients: A Real Risk of Severe Self‐Poisoning. Basic & Clinical Pharmacology & Toxicology 121:4, pages 353-359.
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Sebastian T. Peters, Michael T. Bowen, Kathrin Bohrer, Iain S. McGregor & Inga D. Neumann. (2017) Oxytocin inhibits ethanol consumption and ethanol-induced dopamine release in the nucleus accumbens. Addiction Biology 22:3, pages 702-711.
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Yan Zhou, Rachel Saylor Crowley, Konrad Ben, Thomas E. Prisinzano & Mary Jeanne Kreek. (2017) Synergistic blockade of alcohol escalation drinking in mice by a combination of novel kappa opioid receptor agonist Mesyl Salvinorin B and naltrexone. Brain Research 1662, pages 75-86.
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E. T. Goh & M. Y. Morgan. (2017) Review article: pharmacotherapy for alcohol dependence - the why, the what and the wherefore. Alimentary Pharmacology & Therapeutics 45:7, pages 865-882.
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J. Mutschler & M. Soyka. (2016) Medikamentöse rückfallprophylaktische Behandlung der AlkoholabhängigkeitPharmacological prophylactic treatment for relapse of alcohol dependence. Der Nervenarzt 88:3, pages 303-307.
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Karl Mann, Henri-Jean Aubin & Katie Witkiewitz. (2017) Reduced Drinking in Alcohol Dependence Treatment, What Is the Evidence?. European Addiction Research 23:5, pages 219-230.
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N. W. Gilpin & J. L. Weiner. (2017) Neurobiology of comorbid post-traumatic stress disorder and alcohol-use disorder. Genes, Brain and Behavior 16:1, pages 15-43.
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Michael T. Bowen & Inga D. Neumann. 2018. Behavioral Pharmacology of Neuropeptides: Oxytocin. Behavioral Pharmacology of Neuropeptides: Oxytocin 269 287 .
Michael Soyka & Jochen Mutschler. (2016) Treatment-refractory substance use disorder: Focus on alcohol, opioids, and cocaine. Progress in Neuro-Psychopharmacology and Biological Psychiatry 70, pages 148-161.
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Olga Geisel, Rainer Hellweg & Christian A. Müller. (2016) Serum levels of brain-derived neurotrophic factor in alcohol-dependent patients receiving high-dose baclofen. Psychiatry Research 240, pages 177-180.
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Irene Lorrai, Paola Maccioni, Gian Luigi Gessa & Giancarlo Colombo. (2016) R(+)-Baclofen, but Not S(−)-Baclofen, Alters Alcohol Self-Administration in Alcohol-Preferring Rats. Frontiers in Psychiatry 7.
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Joyce Besheer, Suzanne Frisbee, Patrick A. Randall, Anel A. Jaramillo & Maria Masciello. (2016) Gabapentin potentiates sensitivity to the interoceptive effects of alcohol and increases alcohol self-administration in rats. Neuropharmacology 101, pages 216-224.
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Nora D. Volkow, George F. Koob & A. Thomas McLellan. (2016) Neurobiologic Advances from the Brain Disease Model of Addiction. New England Journal of Medicine 374:4, pages 363-371.
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Yan Zhou & Francesco Leri. 2016. Neuroscience for Addiction Medicine: From Prevention to Rehabilitation - Constructs and Drugs. Neuroscience for Addiction Medicine: From Prevention to Rehabilitation - Constructs and Drugs 237 251 .
Sarah G. Helton & Falk W. Lohoff. (2015) Pharmacogenetics of alcohol use disorders and comorbid psychiatric disorders. Psychiatry Research 230:2, pages 121-129.
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Amy A. Herrold, Angelle M. Sander, Kimberlee V. Wilson, Lauren M. Scimeca, Derin J. Cobia & Hans C. Breiter. (2015) Dual Diagnosis of Traumatic Brain Injury and Alcohol Use Disorder: Characterizing Clinical and Neurobiological Underpinnings. Current Addiction Reports 2:4, pages 273-284.
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D. Dressler, S. Berweck, A. Chatzikalfas, M. Ebke, B. Frank, S. Hesse, M. Huber, J. K. Krauss, K.-H. Mücke, A. Nolte, H.-D. Oelmann, P. W. Schönle, M. Schmutzler, H. Pickenbrock, C. Van der Ven, N. Veelken, M. Vogel, T. Vogt & F. Adib Saberi. (2015) Intrathecal Baclofen therapy in Germany: Proceedings of the IAB—Interdisciplinary Working Group for Movement Disorders Consensus Meeting. Journal of Neural Transmission 122:11, pages 1573-1579.
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Eduardo Costa Pinto, Maressa Danielli Dolzan, Lucio Mendes Cabral, Daniel W. Armstrong & Valéria Pereira de Sousa. (2015) Topiramate: a review of analytical approaches for biological matrices. Biomedical Chromatography 29:10, pages 1461-1472.
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Eduardo Costa Pinto, Maressa Danielli Dolzan, Lucio Mendes Cabral, Daniel W. Armstrong & Valéria Pereira de Sousa. (2015) Topiramate: A Review of Analytical Approaches for the Drug Substance, Its Impurities and Pharmaceutical Formulations. Journal of Chromatographic Science, pages bmv120.
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Christian A. Müller, Olga Geisel, Patricia Pelz, Verena Higl, Josephine Krüger, Anna Stickel, Anne Beck, Klaus-Dieter Wernecke, Rainer Hellweg & Andreas Heinz. (2015) High-dose baclofen for the treatment of alcohol dependence (BACLAD study): A randomized, placebo-controlled trial. European Neuropsychopharmacology 25:8, pages 1167-1177.
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Xiangyang Xie, Wen Lin, Chuanfeng Xing, Yanfang Yang, Qiang Chi, Hui Zhang, Ying Li, Zhiping Li, Yang Yang, Zhenbo Yang & Mingyuang Li. (2015) In Vitro and In Vivo Evaluations of PLGA Microspheres Containing Nalmefene. PLOS ONE 10:5, pages e0125953.
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Sylvie Blairy & Emmanuel Pinto. 2015. L’alcool en questions. L’alcool en questions 129 141 .
Alexander M. Ponizovsky, Paola Rosca, Edward Aronovich, Abraham Weizman & Alexander Grinshpoon. (2015) Baclofen as Add-On to Standard Psychosocial Treatment for Alcohol Dependence: a Randomized, Double-Blind, Placebo-Controlled Trial With 1Year Follow-Up. Journal of Substance Abuse Treatment 52, pages 24-30.
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Antonio Mirijello, Cristina D’Angelo, Anna Ferrulli, Gabriele Vassallo, Mariangela Antonelli, Fabio Caputo, Lorenzo Leggio, Antonio Gasbarrini & Giovanni Addolorato. (2015) Identification and Management of Alcohol Withdrawal Syndrome. Drugs 75:4, pages 353-365.
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Jean-Jacques Chavagnat & Diane Lévy-Chavagnat. (2015) Les médicaments du sevrage et de la réduction de la consommation. Actualités Pharmaceutiques 54:543, pages 26-34.
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María Luisa Gutiérrez García. (2015) Alcohol liver disease: A review of current therapeutic approaches to achieve long-term abstinence. World Journal of Gastroenterology 21:28, pages 8516.
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Beth L. Erwin & Rachel M. Slaton. (2014) Varenicline in the Treatment of Alcohol Use Disorders. Annals of Pharmacotherapy 48:11, pages 1445-1455.
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M. Grall-Bronnec & A. Sauvaget. (2014) The use of repetitive transcranial magnetic stimulation for modulating craving and addictive behaviours: A critical literature review of efficacy, technical and methodological considerations. Neuroscience & Biobehavioral Reviews 47, pages 592-613.
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Audrey MorissetteMDMD, Clairélaine Ouellet-PlamondonMDMD & Didier Jutras-AswadMDMD. (2014) Le craving comme symptôme central de la toxicomanie : de ses fondements neurobiologiques à sa pertinence clinique. Santé mentale au Québec 39:2, pages 21-37.
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