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Drug Evaluations

Treatment of postmenopausal osteoporosis with odanacatib

, MD PhD

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Dieter Brömme, Preety Panwar & Serap Turan. (2016) Cathepsin K osteoporosis trials, pycnodysostosis and mouse deficiency models: Commonalities and differences. Expert Opinion on Drug Discovery 11:5, pages 457-472.
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Barry S Komm, Diana Morgenstern, Luis A Yamamoto & Simon N Jenkins. (2015) The safety and tolerability profile of therapies for the prevention and treatment of osteoporosis in postmenopausal women. Expert Review of Clinical Pharmacology 8:6, pages 769-784.
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Articles from other publishers (10)

Zhengmeng Yang, Lu Feng, Haixing Wang, Yucong Li, Jessica Hiu Tung Lo, Xiaoting Zhang, Xuan Lu, Yaofeng Wang, Sien Lin, Micky D. Tortorella & Gang Li. (2021) DANCR Mediates the Rescuing Effects of Sesamin on Postmenopausal Osteoporosis Treatment via Orchestrating Osteogenesis and Osteoclastogenesis. Nutrients 13:12, pages 4455.
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Jinbin Zhu, Linwei Huang, Wei Dong, Naikai Li, Xingxin Yu, Wei‐Ping Deng & Wenjun Tang. (2019) Enantioselective Rhodium‐Catalyzed Addition of Arylboroxines to N‐Unprotected Ketimines: Efficient Synthesis of Cipargamin. Angewandte Chemie International Edition 58:45, pages 16119-16123.
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Jinbin Zhu, Linwei Huang, Wei Dong, Naikai Li, Xingxin Yu, Wei‐Ping Deng & Wenjun Tang. (2019) Enantioselective Rhodium‐Catalyzed Addition of Arylboroxines to N‐Unprotected Ketimines: Efficient Synthesis of Cipargamin. Angewandte Chemie 131:45, pages 16265-16269.
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Timur T. Tsoriev, Zhanna E. Belaya, Lyudmila Y. Rozhinskaya, Galina A. Mel’nichenko, Aleksandr V. Ilyin, Larisa V. Nikankina & Ivan I. Dedov. (2018) New biomarkers of bone remodelling regulation in patients with acromegaly and endogenous hypercortisolism. Obesity and metabolism 15:3, pages 33-41.
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Roland D. Chapurlat & Cyrille B. Confavreux. (2016) Novel biological markers of bone: from bone metabolism to bone physiology. Rheumatology 55:10, pages 1714-1725.
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Preety Panwar, Kent Søe, Rafael VC Guido, Renata V C Bueno, Jean-Marie Delaisse & Dieter Brömme. (2016) A novel approach to inhibit bone resorption: exosite inhibitors against cathepsin K. British Journal of Pharmacology 173:2, pages 396-410.
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Jure Borišek, Matej Vizovišek, Piotr Sosnowski, Boris Turk, Dušan Turk, Barbara Mohar & Marjana Novič. (2015) Development of N -(Functionalized benzoyl)-homocycloleucyl-glycinonitriles as Potent Cathepsin K Inhibitors . Journal of Medicinal Chemistry 58:17, pages 6928-6937.
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Adeleke H. Aguda, Preety Panwar, Xin Du, Nham T. Nguyen, Gary D. Brayer & Dieter Brömme. (2014) Structural basis of collagen fiber degradation by cathepsin K. Proceedings of the National Academy of Sciences 111:49, pages 17474-17479.
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Marko Fonovi?Boris Turk. (2014) Cysteine cathepsins and extracellular matrix degradation. Biochimica et Biophysica Acta (BBA) - General Subjects 1840:8, pages 2560-2570.
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M. Rauner, U. Föger-Samwald, M.F. Kurz, C. Brünner-Kubath, D. Schamall, A. Kapfenberger, P. Varga, S. Kudlacek, A. Wutzl, H. Höger, P.K. Zysset, G.P. Shi, L.C. Hofbauer, W. Sipos & P. Pietschmann. (2014) Cathepsin S controls adipocytic and osteoblastic differentiation, bone turnover, and bone microarchitecture. Bone 64, pages 281-287.
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