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Original Research

Long-term safety and efficacy of tofogliflozin, a selective inhibitor of sodium-glucose cotransporter 2, as monotherapy or in combination with other oral antidiabetic agents in Japanese patients with type 2 diabetes mellitus: multicenter, open-label, randomized controlled trials

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Read on this site (12)

Shosaku Nomura, Akira Shouzu, Takehito Taniura, Yoshinori Okuda, Seitaro Omoto, Masahiko Suzuki, Tomoki Ito & Nagaoki Toyoda. (2023) Effects of Tofogliflozin and Anagliptin Alone or in Combination on Glucose Metabolism and Atherosclerosis-Related Markers in Patients with Type 2 Diabetes Mellitus. Clinical Pharmacology: Advances and Applications 15, pages 41-55.
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Genya Aharon-Hananel & Itamar Raz. (2019) An evaluation of the efficacy and safety of Tofogliflozin for the treatment of type II diabetes. Expert Opinion on Pharmacotherapy 20:7, pages 781-790.
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Yaowen Wang, Xueting Hu, Xueying Liu & Zengqi Wang. (2016) An overview of the effect of sodium glucose cotransporter 2 inhibitor monotherapy on glycemic and other clinical laboratory parameters in type 2 diabetes patients. Therapeutics and Clinical Risk Management 12, pages 1113-1131.
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Kalliopi Pafili, Efstratios Maltezos & Nikolaos Papanas. (2016) Pharmacokinetic and pharmacodynamic drug evaluation of tofogliflozin for the treatment of type 2 diabetes. Expert Opinion on Drug Metabolism & Toxicology 12:11, pages 1367-1380.
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Hiroyuki Ito, Masahiro Shinozaki, Shinya Nishio & Mariko Abe. (2016) SGLT2 inhibitors in the pipeline for the treatment of diabetes mellitus in Japan. Expert Opinion on Pharmacotherapy 17:15, pages 2073-2084.
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K. Pafili, E. Maltezos & N. Papanas. (2016) The potential of SGLT2 inhibitors in phase II clinical development for treating type 2 diabetes. Expert Opinion on Investigational Drugs 25:10, pages 1133-1152.
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Shuji Kinoshita & Kazuoki Kondo. (2015) Evaluation of pharmacokinetic and pharmacodynamic interactions of canagliflozin and teneligliptin in Japanese healthy male volunteers. Expert Opinion on Drug Metabolism & Toxicology 11:1, pages 7-14.
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Kalliopi Pafili & Nikolaos Papanas. (2014) Tofogliflozin: the road goes ever on. Expert Opinion on Pharmacotherapy 15:9, pages 1197-1201.
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Toshinari Takamura, Kohei Kaku, Akihiro Yoshida, Hiromi Kusakabe, Hiroyuki Nakamura & Hideki Suganami. (2023) Reductions in liver enzymes are associated with anti‐hyperglycaemic and anti‐obesity effects of tofogliflozin in people with type 2 diabetes: Post‐hoc analyses. Endocrinology, Diabetes & Metabolism.
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Youn Huh & Young Sik Kim. (2022) Predictors for successful weight reduction during treatment with Dapagliflozin among patients with type 2 diabetes mellitus in primary care. BMC Primary Care 23:1.
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Rune E. Kuhre, Carolyn F. Deacon, Nicolai J. Wewer Albrechtsen & Jens J. Holst. (2021) Do sodium‐glucose co‐transporter‐2 inhibitors increase plasma glucagon by direct actions on the alpha cell? And does the increase matter for the associated increase in endogenous glucose production?. Diabetes, Obesity and Metabolism 23:9, pages 2009-2019.
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