Advanced search
Publication Cover
Expert Opinion on Pharmacotherapy Volume 15, 2014 - Issue 17
Submit an article Journal homepage
1,212
Views
28
CrossRef citations to date
0
Altmetric
Reviews

Therapies for inter-relating diabetes and obesity – GLP-1 and obesity

Eva W IepsenUniversity of Copenhagen, Department of Biomedical Sciences, Faculty of Health and Medical Sciences, Blegdamsvej 3B, Copenhagen 2200, Denmark
, MD,
Signe S TorekovUniversity of Copenhagen, Department of Biomedical Sciences, Faculty of Health and Medical Sciences, Blegdamsvej 3B, Copenhagen 2200, Denmark
&
Jens J HolstUniversity of Copenhagen, Copenhagen, [email protected]
Pages 2487-2500 | Published online: 26 Sep 2014

Citations (28)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (2)

Xueying Tan, Xiaojing Cao, Minzhi Zhou, Ping Zou & Jingbo Hu. (2017) Efficacy and safety of once-weekly semaglutide for the treatment of type 2 diabetes. Expert Opinion on Investigational Drugs 26:9, pages 1083-1089.
Read now
Eva Winning Iepsen, Signe Sørensen Torekov & Jens Juul Holst. (2015) Liraglutide for Type 2 diabetes and obesity: a 2015 update. Expert Review of Cardiovascular Therapy 13:7, pages 753-767.
Read now

Articles from other publishers (26)

Jing-Yue Wang, Quan-Wei Wang, Xin-Yu Yang, Wei Yang, Dong-Rui Li, Jing-Yu Jin, Hui-Cong Zhang & Xian-Feng Zhang. (2023) GLP−1 receptor agonists for the treatment of obesity: Role as a promising approach. Frontiers in Endocrinology 14.
Crossref
Despoina Myrsini Galetaki, Charles L. Cai, Kulsajan S. Bhatia, Vivian Chin, Jacob V. Aranda & Kay D. Beharry. (2023) Biomarkers of growth and carbohydrate metabolism in neonatal rats supplemented with fish oil and/or antioxidants during intermittent hypoxia. Growth Hormone & IGF Research 68, pages 101513.
Crossref
Jasna Klen & Vita Dolžan. (2022) Glucagon-like Peptide-1 Receptor Agonists in the Management of Type 2 Diabetes Mellitus and Obesity: The Impact of Pharmacological Properties and Genetic Factors. International Journal of Molecular Sciences 23:7, pages 3451.
Crossref
Jari-Pekka Klemettilä, Anssi Solismaa, Niko Seppälä, Mari Hämäläinen, Eeva Moilanen, Esa Leinonen & Olli Kampman. (2021) Glucagon-like peptide-1 serum levels are associated with weight gain in patients treated with clozapine. Psychiatry Research 306, pages 114227.
Crossref
Yewei Wang, Dandan Wang, Jie Cheng, Xinyu Fang, Yan Chen, Lingfang Yu, Juanjuan Ren, Yuan Tian & Chen Zhang. (2021) Efficacy and tolerability of pharmacological interventions on metabolic disturbance induced by atypical antipsychotics in adults: A systematic review and network meta-analysis. Journal of Psychopharmacology 35:9, pages 1111-1119.
Crossref
Zengbing Lu, Sze Wa Chan, Longlong Tu, Man Piu Ngan & John A. Rudd. (2020) GLP-1 receptors are involved in the GLP-1 (7–36) amide-induced modulation of glucose homoeostasis, emesis and feeding in Suncus murinus (house musk shrew). European Journal of Pharmacology 888, pages 173528.
Crossref
Giulia Cantini, Martina Trabucco, Ilaria Dicembrini, Edoardo Mannucci & Michaela Luconi. 2020. Hormonal Signaling in Biology and Medicine. Hormonal Signaling in Biology and Medicine 361 381 .
Yun Sok Lee, Matthew RiopelPedro Cabrales & Guatam K. Bandyopadhyay. (2019) Hepatocyte-specific HIF-1α ablation improves obesity-induced glucose intolerance by reducing first-pass GLP-1 degradation. Science Advances 5:7.
Crossref
Fredrik Anesten, Adrià Dalmau Gasull, Jennifer E. Richard, Imre Farkas, Devesh Mishra, Lilly Taing, Fuping Zhang, Matti Poutanen, Vilborg Palsdottir, Zsolt Liposits, Karolina P. Skibicka & John‐Olov Jansson. (2019) Interleukin‐6 in the central amygdala is bioactive and co‐localised with glucagon‐like peptide‐1 receptor. Journal of Neuroendocrinology 31:6, pages e12722.
Crossref
Yao Gao, XingYun Wang, FangYan Huang, XianWei Cui, Yun Li, Xing Wang, Yan Cao, PengFei Xu, KaiPeng Xie, RanRan Tang, Le Zhang, ChenBo Ji, LiangHui You & XiRong Guo. (2017) Identification and characterization of metformin on peptidomic profiling in human visceral adipocytes. Journal of Cellular Biochemistry 119:2, pages 1866-1878.
Crossref
F. Anesten, C. Santos, E. Gidestrand, E. Schéle, V. Pálsdóttir, T. Swedung-Wettervik, B. Meister, K. Patrycja Skibicka & J.-O. Jansson. (2017) Functional interleukin-6 receptor-α is located in tanycytes at the base of the third ventricle. Journal of Neuroendocrinology 29:12, pages e12546.
Crossref
Line Engelbrechtsen, Eva Pers Winning Iepsen, Ehm A. Andersson, Yuvaraj Mahendran, Julie Lundgren, Anna Elisabet Jonsson, Sten Madsbad, Jens Juul Holst, Henrik Vestergaard, Torben Hansen & Signe Sørensen Torekov. (2016) Weight loss and weight maintenance obtained with or without GLP-1 analogue treatment decrease branched chain amino acid levels. Metabolomics 12:12.
Crossref
A. PANKOVA, E. KRALIKOVA, P. KAVALKOVA, L. STEPANKOVA, K. ZVOLSKA & M. HALUZIK. (2016) No Change in Serum Incretins Levels but Rise of Leptin Levels After Smoking Cessation: a Pilot Study. Physiological Research, pages 651-659.
Crossref
Fredrik AnestenMarie K. Holt, Erik SchéleVilborg PálsdóttirFrank Reimann, Fiona M. Gribble, Cecilia SafariKarolina P. SkibickaStefan Trapp & John-Olov Jansson. (2016) Preproglucagon neurons in the hindbrain have IL-6 receptor-α and show Ca 2+ influx in response to IL-6 . American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 311:1, pages R115-R123.
Crossref
A. L. João, F. Reis & R. Fernandes. (2016) The incretin system ABCs in obesity and diabetes - novel therapeutic strategies for weight loss and beyond. Obesity Reviews 17:7, pages 553-572.
Crossref
Karla Mayfield, Dan Siskind, Karl Winckel, Anthony W Russell, Steve Kisely, Greg Smith & Samantha Hollingworth. (2016) Glucagon-like peptide-1 agonists combating clozapine-associated obesity and diabetes. Journal of Psychopharmacology 30:3, pages 227-236.
Crossref
Rexford S. Ahima. 2016. Metabolic Syndrome. Metabolic Syndrome 797 809 .
Hao Wu, Valentina Tremaroli & Fredrik Bäckhed. (2015) Linking Microbiota to Human Diseases: A Systems Biology Perspective. Trends in Endocrinology & Metabolism 26:12, pages 758-770.
Crossref
L. Brown, H. Poudyal & S. K. Panchal. (2015) Functional foods as potential therapeutic options for metabolic syndrome. Obesity Reviews 16:11, pages 914-941.
Crossref
Modjtaba Zandian, Cecilia Bergh, Ioannis Ioakimidis, Maryam Esfandiari, Julian Shield, Stafford Lightman, Michael Leon & Per Södersten. (2015) Control of Body Weight by Eating Behavior in Children. Frontiers in Pediatrics 3.
Crossref
Meng Li, Shilun Li & Yukun Li. (2015) Liraglutide Promotes Cortical Neurite Outgrowth via the MEK?ERK Pathway. Cellular and Molecular Neurobiology 35:7, pages 987-993.
Crossref
Aline Haas de Mello, Morgana Prá, Larissa Colonetti Cardoso, Rosiane de Bona Schraiber & Gislaine Tezza Rezin. (2015) Incretin-based therapies for obesity treatment. Metabolism 64:9, pages 967-981.
Crossref
E W Iepsen, J Lundgren, C Dirksen, J-EB Jensen, O Pedersen, T Hansen, S Madsbad, J J Holst & S S Torekov. (2014) Treatment with a GLP-1 receptor agonist diminishes the decrease in free plasma leptin during maintenance of weight loss. International Journal of Obesity 39:5, pages 834-841.
Crossref
Lesley J. Scott. (2015) Liraglutide: A Review of Its Use in the Management of Obesity. Drugs 75:8, pages 899-910.
Crossref
Hermann Toplak, Euan Woodward, Volkan Yumuk, Jean-Michel Oppert, Jason C.G. Halford & Gema Frühbeck. (2015) 2014 EASO Position Statement on the Use of Anti-Obesity Drugs. Obesity Facts 8:3, pages 166-174.
Crossref
Rexford S. Ahima. 2014. Metabolic Syndrome. Metabolic Syndrome 1 16 .

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.