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Drug Evaluation

Fixed-dose combination of sofosbuvir and ledipasvir for the treatment of chronic hepatitis C genotype 1

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Yan A. Ivanenkov, Vladimir A. Aladinskiy, Nikolay A. Bushkov, Andrey A. Ayginin, Alexander G. Majouga & Alexandre V. Ivachtchenko. (2017) Small-molecule inhibitors of hepatitis C virus (HCV) non-structural protein 5A (NS5A): a patent review (2010-2015). Expert Opinion on Therapeutic Patents 27:4, pages 401-414.
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Annarosa Floreani. (2015) Perspectives of fixed daily dose of sofosbuvir and ledipasvir for the treatment of chronic hepatitis C. Expert Opinion on Pharmacotherapy 16:6, pages 801-804.
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Shivam Chowdhary, Rahul Deka, Kingshuk Panda, Rohit Kumar, Abhishikt David Solomon, Jimli Das, Supriya Kanoujiya, Ashish Kumar Gupta, Somya Sinha, Janne Ruokolainen, Kavindra Kumar Kesari & Piyush Kumar Gupta. (2023) Recent Updates on Viral Oncogenesis: Available Preventive and Therapeutic Entities. Molecular Pharmaceutics 20:8, pages 3698-3740.
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Zhiguo Wang & Baofeng YangZhiguo Wang & Baofeng Yang. 2022. Polypharmacology. Polypharmacology 301 321 .
Andrey V. Smolobochkin, Rakhymzhan A. Turmanov, Almir S. Gazizov, Elizaveta A. Kuznetsova, Alexander R. Burilov & Mikhail A. Pudovik. (2020) Synthesis of Novel 2-Hetarylpyrrolidines via the Reaction of N-(4,4-diethoxybutyl)amidophosphates with C-nucleophiles. Chemistry of Heterocyclic Compounds 56:10, pages 1363-1365.
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Ameer Abutaleb, Shyam Kottilil & Eleanor Wilson. (2018) Glecaprevir/pibrentasvir expands reach while reducing cost and duration of hepatitis C virus therapy. Hepatology International 12:3, pages 214-222.
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Rebecca Lee, Shyam Kottilil & Eleanor Wilson. (2016) Sofosbuvir/velpatasvir: a pangenotypic drug to simplify HCV therapy. Hepatology International 11:2, pages 161-170.
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Yi Li, Qing-Zhu Li, Li Huang, Hong Liang, Kai-Chuan Yang, Hai-Jun Leng, Yue Liu, Xu-Dong Shen, Xiao-Jun Gou & Jun-Long Li. (2017) Diastereoselective Synthesis of Spirocyclopropanes under Mild Conditions via Formal [2 + 1] Cycloadditions Using 2,3-Dioxo-4-benzylidene-pyrrolidines. Molecules 22:2, pages 328.
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A. Ferreira-Gonzalez. 2017. Diagnostic Molecular Pathology. Diagnostic Molecular Pathology 485 501 .
N.A. Meanwell. 2017. Comprehensive Medicinal Chemistry III. Comprehensive Medicinal Chemistry III 553 627 .
Nannan Zhou, Zhou Han, Sandra Hartman-Neumann, Brenda DeGray, Joseph Ueland, Vincent Vellucci, Dennis Hernandez & Fiona McPhee. (2016) Characterization of NS5A polymorphisms and their impact on response rates in patients with HCV genotype 2 treated with daclatasvir-based regimens. Journal of Antimicrobial Chemotherapy 71:12, pages 3495-3505.
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Nicholas A. Meanwell. (2016) 2015 Philip S. Portoghese Medicinal Chemistry Lectureship. Curing Hepatitis C Virus Infection with Direct-Acting Antiviral Agents: The Arc of a Medicinal Chemistry Triumph. Journal of Medicinal Chemistry 59:16, pages 7311-7351.
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Chenwei Pan, Yongping Chen, Weilai Chen, Guangyao Zhou, Lingxiang Jin, Yi Zheng, Wei Lin & Zhenzhen Pan. (2016) Simultaneous determination of ledipasvir, sofosbuvir and its metabolite in rat plasma by UPLC–MS/MS and its application to a pharmacokinetic study. Journal of Chromatography B 1008, pages 255-259.
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