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Review

Polycystic ovary syndrome: chemical pharmacotherapy

, MD, , MD, , MD, , MD, , MD, , MD, , MD, , PhD & , PhD show all

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Read on this site (5)

Ilaria Soave, Tommaso Occhiali, Chiara Assorgi, Roberto Marci & Donatella Caserta. (2020) Environmental toxin exposure in polycystic ovary syndrome women and possible ovarian neoplastic repercussion. Current Medical Research and Opinion 36:4, pages 693-703.
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Roberta Venturella, Alberto Vaiarelli, Danilo Cimadomo, Sara Pedri, Daniela Lico, Rossella Mazzilli, Rita Mocciaro, Laura Rienzi, Costantino Di Carlo, Filippo Maria Ubaldi & Fulvio Zullo. (2019) State of the art and emerging drug therapies for female infertility. Gynecological Endocrinology 35:10, pages 835-841.
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Giovanni Monastra, Vittorio Unfer, Abdel Halim Harrath & Mariano Bizzarri. (2017) Combining treatment with myo-inositol and D-chiro-inositol (40:1) is effective in restoring ovary function and metabolic balance in PCOS patients. Gynecological Endocrinology 33:1, pages 1-9.
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Forough Javanmanesh, Maryam Kashanian, Maryam Rahimi & Narges Sheikhansari. (2016) A comparison between the effects of metformin and N-acetyl cysteine (NAC) on some metabolic and endocrine characteristics of women with polycystic ovary syndrome. Gynecological Endocrinology 32:4, pages 285-289.
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Morena Luigia Rocca, Roberta Venturella, Rita Mocciaro, Fulvio Zullo & Michele Morelli. (2016) Will emerging pharmacotherapies improve the management of polycystic ovarian syndrome?. Expert Opinion on Emerging Drugs 21:1, pages 1-4.
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Articles from other publishers (25)

Stephanie E. Areloegbe, Atuma L. Chukwubueze, Adewumi O. Oyabambi & Kehinde S. Olaniyi. (2023) Low-dose spironolactone attenuates metabolic defects in the skeletal muscle of letrozole-induced hyperandrogenic female rats. Nutrire 48:1.
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Viktor V. Smirnov, Narasimha M. Beeraka, Dmitry Yu Butko, Vladimir N. Nikolenko, Sergey A. Bondarev, Evgeniy E. Achkasov, Mikhail Y. Sinelnikov & P. R. Hemanth Vikram. (2022) Updates on Molecular Targets and Epigenetic-Based Therapies for PCOS. Reproductive Sciences 30:3, pages 772-786.
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Hilal ER & Pınar GOBEL. (2022) Polikistik Over Sendromunun Beslenme Tedavisinde Berberinin Yeri. Avrasya Sağlık Bilimleri Dergisi 6:1, pages 43-49.
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Ali Aflatounian, Valentina Rodriguez Paris, Dulama Richani, Melissa C. Edwards, Blake J. Cochran, William L. Ledger, Robert B. Gilchrist, Michael J. Bertoldo, Lindsay E. Wu & Kirsty A. Walters. (2022) Declining muscle NAD+ in a hyperandrogenism PCOS mouse model: Possible role in metabolic dysregulation. Molecular Metabolism 65, pages 101583.
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Kyoung Sun Park, Weijuan Gang, Pyung-Wha Kim, Changsop Yang, Purumea Jun, So-Young Jung, Ojin Kwon, Jin Moo Lee, Hye Jeong Lee, Su Jeong Lee, Xianghong Jing, Ning Zhang, Jing Hu, Jiping Zhao, Ran Pang, Chunlan Jin & Jun-Hwan Lee. (2022) Efficacy and safety of acupuncture on oligomenorrhea due to polycystic ovary syndrome. Medicine 101:7, pages e28674.
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Xiaohong Chen, Hongliang Tang, Yingye Liang, Pingting Wu, Liuhong Xie, Yao Ding, Peng Yang, Bingcai Long & Jing Lin. (2021) Acupuncture regulates the autophagy of ovarian granulosa cells in polycystic ovarian syndrome ovulation disorder by inhibiting the PI3K/AKT/mTOR pathway through LncMEG3. Biomedicine & Pharmacotherapy 144, pages 112288.
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Mariangela Rondanelli, Antonella Riva, Giovanna Petrangolini, Pietro Allegrini, Attilio Giacosa, Teresa Fazia, Luisa Bernardinelli, Clara Gasparri, Gabriella Peroni & Simone Perna. (2021) Berberine Phospholipid Is an Effective Insulin Sensitizer and Improves Metabolic and Hormonal Disorders in Women with Polycystic Ovary Syndrome: A One-Group Pretest–Post-Test Explanatory Study. Nutrients 13:10, pages 3665.
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Kou Xu, Jiajie Wang, Feng Hu, Siying Lv, Yanji Zhang, Qiqi Yang, Wei Huang & Zhongyu Zhou. (2021) Effects of moxibustion on reproduction and metabolism of polycystic ovary syndrome: a protocol for meta-analysis and systematic review. BMJ Open 11:8, pages e049039.
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Irene E Sucquart, Ruchi Nagarkar, Melissa C Edwards, Valentina Rodriguez Paris, Ali Aflatounian, Michael J Bertoldo, Rebecca E Campbell, Robert B Gilchrist, Denovan P Begg, David J Handelsman, Vasantha Padmanabhan, Richard A Anderson & Kirsty A Walters. (2021) Neurokinin 3 Receptor Antagonism Ameliorates Key Metabolic Features in a Hyperandrogenic PCOS Mouse Model. Endocrinology 162:5.
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Fatemeh Pourteymour Fard Tabrizi, Fatemeh Hajizadeh-Sharafabad, Maryam Vaezi, Hamed Jafari-Vayghan, Mohammad Alizadeh & Vahid Maleki. (2020) Quercetin and polycystic ovary syndrome, current evidence and future directions: a systematic review. Journal of Ovarian Research 13:1.
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M. Rondanelli, Vittoria Infantino, A. Riva, G. Petrangolini, M. A. Faliva, G. Peroni, M. Naso, M. Nichetti, D. Spadaccini, C. Gasparri & S. Perna. (2020) Polycystic ovary syndrome management: a review of the possible amazing role of berberine. Archives of Gynecology and Obstetrics 301:1, pages 53-60.
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D. Romualdi, V. Versace, V. Tagliaferri, S. De Cicco, V. Immediata, R. Apa, M. Guido & A. Lanzone. (2019) The resting metabolic rate in women with polycystic ovary syndrome and its relation to the hormonal milieu, insulin metabolism, and body fat distribution: a cohort study. Journal of Endocrinological Investigation 42:9, pages 1089-1097.
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Holly R Harris, Kara L Cushing-Haugen, Penelope M Webb, Christina M Nagle, Susan J Jordan, Harvey A Risch, Mary Anne Rossing, Jennifer A Doherty, Marc T Goodman, Francesmary Modugno, Roberta B Ness, Kirsten B Moysich, Susanne K Kjær, Estrid Høgdall, Allan Jensen, Joellen M Schildkraut, Andrew Berchuck, Daniel W Cramer, Elisa V Bandera, Lorna Rodriguez, Nicolas Wentzensen, Joanne Kotsopoulos, Steven A Narod, John R McLaughlin, Hoda Anton-Culver, Argyrios Ziogas, Celeste L Pearce, Anna H Wu, Sara Lindström & Kathryn L Terry. (2019) Association between genetically predicted polycystic ovary syndrome and ovarian cancer: a Mendelian randomization study. International Journal of Epidemiology 48:3, pages 822-830.
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Jing Jin, Qiao‑Yun Hu, Wen‑Wen Xu, Wen‑Jia Zhu, Bei Liu, Jing Liu, Wei Wang & Hui‑Fang Zhou. (2019) Tanshinone IIA attenuates estradiol‑induced polycystic ovarian syndrome in mice by ameliorating FSHR expression in the ovary. Experimental and Therapeutic Medicine.
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Madeleine Ong, Jing Cheng, Xingliang Jin, Weiguo Lao, Michael Johnson, Yi Tan & Xianqin Qu. (2019) Paeoniflorin extract reverses dexamethasone-induced testosterone over-secretion through downregulation of cytochrome P450 17A1 expression in primary murine theca cells. Journal of Ethnopharmacology 229, pages 97-103.
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Sandro La Vignera, Rosita A. Condorelli, Rossella Cannarella, Ylenia Duca & Aldo E. Calogero. (2018) Sport, doping and female fertility. Reproductive Biology and Endocrinology 16:1.
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Alessandro Conforti, Marika Mascia, Giuseppina Cioffi, Cristina De Angelis, Giuseppe Coppola, Pasquale De Rosa, Rosario Pivonello, Carlo Alviggi & Giuseppe De Placido. (2018) Air pollution and female fertility: a systematic review of literature. Reproductive Biology and Endocrinology 16:1.
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Chan-Young Kwon, Boram Lee & Kyoung Sun Park. (2018) Oriental herbal medicine and moxibustion for polycystic ovary syndrome. Medicine 97:43, pages e12942.
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Vahid Maleki, Azimeh Izadi, Alireza Farsad-Naeimi & Mohammad Alizadeh. (2018) Chromium supplementation does not improve weight loss or metabolic and hormonal variables in patients with polycystic ovary syndrome: A systematic review. Nutrition Research 56, pages 1-10.
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Jing Zhou, Likun Yang, Jinna Yu, Yang Wang & Zhishun Liu. (2017) Efficacy of acupuncture on menstrual frequency in women with polycystic ovary syndrome. Medicine 96:47, pages e8828.
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H.R. Harris, L.J. Titus, D.W. Cramer & K.L. Terry. (2017) Long and irregular menstrual cycles, polycystic ovary syndrome, and ovarian cancer risk in a population-based case-control study. International Journal of Cancer 140:2, pages 285-291.
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Madeleine Ong, Jie Peng, Xingliang Jin & Xianqin Qu. (2017) Chinese Herbal Medicine for the Optimal Management of Polycystic Ovary Syndrome. The American Journal of Chinese Medicine 45:03, pages 405-422.
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Holly R. Harris & Kathryn L. Terry. (2016) Polycystic ovary syndrome and risk of endometrial, ovarian, and breast cancer: a systematic review. Fertility Research and Practice 2:1.
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Jyothis T. GeorgeRahul Kakkar, Jayne Marshall, Martin L. Scott, Richard D. Finkelman, Tony W. Ho, Johannes VeldhuisKarolina Skorupskaite, Richard A. Anderson, Stuart McIntosh & Lorraine Webber. (2016) Neurokinin B Receptor Antagonism in Women With Polycystic Ovary Syndrome: A Randomized, Placebo-Controlled Trial. The Journal of Clinical Endocrinology & Metabolism 101:11, pages 4313-4321.
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Yu Wang, Xin Fu, Jing Xu, Qiuhong Wang & Haixue Kuang. (2016) Systems pharmacology to investigate the interaction of berberine and other drugs in treating polycystic ovary syndrome. Scientific Reports 6:1.
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