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Drug Evaluation

Alosetron and irritable bowel syndrome

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Pages 2089-2098 | Published online: 02 Mar 2005

Keep up to date with the latest research on this topic with citation updates for this article.

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Youhoon Chong & Hyunah Choo. (2010) 5-HT3 antagonists under development. Expert Opinion on Investigational Drugs 19:11, pages 1309-1319.
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M. B. Hansen, F. Arif, L. Wallin & J. F. Pedersen. (2006) Serotonin and superior mesenteric artery resistance index. Scandinavian Journal of Clinical and Laboratory Investigation 66:5, pages 395-406.
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Crossref
Lori A. Mahajan & Barbara Kaplan. 2011. Pediatric Gastrointestinal and Liver Disease. Pediatric Gastrointestinal and Liver Disease 66 79.e3 .
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Crossref
Neehar Parikh & Colin W. Howden. (2010) The Safety of Drugs Used in Acid-related Disorders and Functional Gastrointestinal Disorders. Gastroenterology Clinics of North America 39:3, pages 529-542.
Crossref
k. ohashi-doi, d. himaki, k. nagao, m. kawai, j. d. gale, j. b. furness & y. kurebayashi. (2010) A selective, high affinity 5-HT 2B receptor antagonist inhibits visceral hypersensitivity in rats . Neurogastroenterology & Motility 22:2, pages e69-e76.
Crossref
Alexandru Gaman, Maria Cristina Bucur & Braden Kuo. (2009) Review: Therapeutic advances in functional gastrointestinal disease: irritable bowel syndrome. Therapeutic Advances in Gastroenterology 2:3, pages 169-181.
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Crossref
D. T. Beattie & J. A. M. Smith. (2008) Serotonin pharmacology in the gastrointestinal tract: a review. Naunyn-Schmiedeberg's Archives of Pharmacology 377:3, pages 181-203.
Crossref
David C.E. Bulmer, Anne-Marie Coelho & Wendy J. Winchester. (2007) Approaches to the treatment of visceral pain. Drug Discovery Today: Therapeutic Strategies 4:3, pages 171-176.
Crossref
B. Coffin. (2007) Douleurs et syndrome de l’intestin irritable : prise en charge thérapeutique à la lumière des nouvelles pistes physiopathologiquesPain and irritable bowel syndrome : therapeutic options in light of recent pathophysiological approaches. Côlon & Rectum 1:3, pages 184-189.
Crossref
Brian E. Lacy & L. Campbell Levy. (2007) Lubiprostone. Journal of Clinical Gastroenterology 41:4, pages 345-351.
Crossref
E. A. MAYER, K. TILLISCH & S. BRADESI. (2006) Review article: modulation of the brain–gut axis as a therapeutic approach in gastrointestinal disease. Alimentary Pharmacology and Therapeutics 24:6, pages 919-933.
Crossref
J. TACK, M. FRIED, L. A. HOUGHTON, J. SPICAK & G. FISHER. (2006) Systematic review: the efficacy of treatments for irritable bowel syndrome - a European perspective. Alimentary Pharmacology and Therapeutics 24:2, pages 183-205.
Crossref
Evan S. Dellon & Yehuda Ringel. (2006) Treatment of functional diarrhea. Current Treatment Options in Gastroenterology 9:4, pages 331-342.
Crossref
Tim Hammond & Jean-Pierre Valentin. 2006. The Process of New Drug Discovery and Development, Second Edition. The Process of New Drug Discovery and Development, Second Edition 243 289 .
Hugo Gallo-Torres, Allen Brinker & Mark Avigan. (2006) Alosetron: Ischemic Colitis and Serious Complications of Constipation. The American Journal of Gastroenterology 101:5, pages 1080-1083.
Crossref
Timothy J Ness. (2005) Pelvic pain in women and men: recent findings. Current Opinion in Anaesthesiology 18:5, pages 555-562.
Crossref
Benoit Coffin, Jean-Marc Sabaté & Didier Bouhassira. (2005) Douleurs et syndrome de l’intestin irritable. Gastroentérologie Clinique et Biologique 29:8-9, pages 769-771.
Crossref
Georges Coremans. (2005) Cilansetron: a novel, high-affinity 5-HT 3 receptor antagonist for irritable bowel syndrome with diarrhea predominance . Therapy 2:4, pages 559-567.
Crossref
James J Galligan. (2004) Enteric P2X receptors as potential targets for drug treatment of the irritable bowel syndrome. British Journal of Pharmacology 141:8, pages 1294-1302.
Crossref
Colin D Rudolph & Adrian Miranda. (2004) Treatment Options for Functional Abdominal Pain. Pediatric Annals 33:2, pages 105-112.
Crossref

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