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Does pharmacogenetics have the potential to allow the individualisation of immunosuppressive drug dosing in organ transplantation?

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Pages 2593-2605 | Published online: 30 Nov 2005

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Fu Liang NG, David W Holt & Iain AM MacPhee. (2007) Pharmacogenetics as a tool for optimising drug therapy in solid-organ transplantation. Expert Opinion on Pharmacotherapy 8:13, pages 2045-2058.
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Guillermo Gervasini, Julio Benítez & Juan Antonio Carrillo. (2010) Pharmacogenetic testing and therapeutic drug monitoring are complementary tools for optimal individualization of drug therapy. European Journal of Clinical Pharmacology 66:8, pages 755-774.
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Christine E. Staatz, Lucy K. Goodman & Susan E. Tett. (2010) Effect of CYP3A and ABCB1 Single Nucleotide Polymorphisms on the Pharmacokinetics and Pharmacodynamics of Calcineurin Inhibitors: Part I. Clinical Pharmacokinetics 49:3, pages 141-175.
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Sung-In Park, Claudia R. Felipe, Paula G. Pinheiro-Machado, Riberto Garcia, Fernanda B. Fernandes, Dulce E. Casarini, Helio Tedesco-SilvaJrJr & Jose O. Medina-Pestana. (2009) Tacrolimus pharmacokinetic drug interactions: effect of prednisone, mycophenolic acid or sirolimus. Fundamental & Clinical Pharmacology 23:1, pages 137-145.
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Chandra Prakash & Alfin D. N. Vaz. 2008. Nuclear Receptors in Drug Metabolism. Nuclear Receptors in Drug Metabolism 1 41 .
Dany Anglicheau, Christophe LegendrePhilippe Beaune & Eric Thervet. (2007) Cytochrome P450 3A polymorphisms and immunosuppressive drugs: an update . Pharmacogenomics 8:7, pages 835-849.
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Sharon Marsh, Derek J Van BoovenHoward L McLeod. (2006) Global pharmacogenetics: giving the genome to the masses. Pharmacogenomics 7:4, pages 625-631.
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