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Drug Evaluation

Indinavir: the forgotten HIV-protease inhibitor. Does it still have a role?

Pages 957-964 | Published online: 01 May 2007

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Ilaria Testi, Aniruddha Agarwal, Rupesh Agrawal, Sarakshi Mahajan, Alessandro Marchese, Elisabetta Miserocchi & Vishali Gupta. (2020) Drug-induced Uveitis in HIV Patients with Ocular Opportunistic Infections. Ocular Immunology and Inflammation 28:7, pages 1069-1075.
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Julieta C. Imperiale, Gabriela Bevilacqua, Paulo de Tarso Vieira e Rosa & Alejandro Sosnik. (2014) Production of pure indinavir free base nanoparticles by a supercritical anti-solvent (SAS) method. Drug Development and Industrial Pharmacy 40:12, pages 1607-1615.
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Yuan Peng, Yanjun Zong, Dongfeng Wang, Junbing Chen, Zhe-Sheng Chen, Fujun Peng & Zhijun Liu. (2023) Current drugs for HIV-1: from challenges to potential in HIV/AIDS. Frontiers in Pharmacology 14.
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Rui Wang, Andrew M. Piggott, Yit-Heng Chooi & Hang Li. (2023) Discovery, bioactivity and biosynthesis of fungal piperazines. Natural Product Reports 40:2, pages 387-411.
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Edward T. Ledingham, Kieran P. Stockton & Ben W. Greatrex. (2017) Efficient Synthesis of an Indinavir Precursor from Biomass-Derived (–)-Levoglucosenone. Australian Journal of Chemistry 70:10, pages 1146.
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. 2016. Meyler's Side Effects of Drugs. Meyler's Side Effects of Drugs 54 60 .
Alejandro Sosnik, Julieta C. Imperiale, Brenda Vázquez-González, Maya Menaker Raskin, Franklin Muñoz-Muñoz, Guillermina Burillo, Gerardo Cedillo & Emilio Bucio. (2015) Mucoadhesive thermo-responsive chitosan- g -poly( N -isopropylacrylamide) polymeric micelles via a one-pot gamma-radiation-assisted pathway. Colloids and Surfaces B: Biointerfaces 136, pages 900-907.
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Julieta C. Imperiale, Pablo Nejamkin, Maria J. del Sole, Carlos E. Lanusse & Alejandro Sosnik. (2015) Novel protease inhibitor-loaded Nanoparticle-in-Microparticle Delivery System leads to a dramatic improvement of the oral pharmacokinetics in dogs. Biomaterials 37, pages 383-394.
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Nico Holmstock, Tom De Bruyn, Jan Bevernage, Pieter Annaert, Raf Mols, Jan Tack & Patrick Augustijns. (2013) Exploring food effects on indinavir absorption with human intestinal fluids in the mouse intestine. European Journal of Pharmaceutical Sciences 49:1, pages 27-32.
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Chandrabose Selvaraj, Sanjeev Kumar Singh, Sunil Kumar Tripathi, Karnati Konda Reddy & Murugappan Rama. (2011) In silico screening of indinavir-based compounds targeting proteolytic activity in HIV PR: binding pocket fit approach. Medicinal Chemistry Research 21:12, pages 4060-4068.
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Anat Levit, Talia Yarnitzky, Ayana Wiener, Rina Meidan & Masha Y. Niv. (2011) Modeling of Human Prokineticin Receptors: Interactions with Novel Small-Molecule Binders and Potential Off-Target Drugs. PLoS ONE 6:11, pages e27990.
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Alma Viso, Roberto Fernández de la Pradilla, Mariola Tortosa, Ana García & Aida Flores. (2011) Update 1 of: α,β-Diamino Acids: Biological Significance and Synthetic Approaches. Chemical Reviews 111:2, pages PR1-PR42.
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Oliver Koch, Susanne Sheehy, Catherine Sargent, Jane Democratis, Sarah Abbas, Jurgen Schiefermueller & Brian J. Angus. 2010. Side Effects of Drugs Annual 32 - A worldwide yearly survey of new data and trends in adverse drug reactions and interactions. Side Effects of Drugs Annual 32 - A worldwide yearly survey of new data and trends in adverse drug reactions and interactions 529 553 .
Tim O. Lankisch, Georg Behrens, Ursula Ehmer, Ulrike Möbius, Juergen Rockstroh, Michael Wehmeier, Sandra Kalthoff, Nicole Freiberg, Michael P. Manns, Reinhold E. Schmidt & Christian P. Strassburg. (2009) Gilbert’s syndrome and hyperbilirubinemia in protease inhibitor therapy – An extended haplotype of genetic variants increases risk in indinavir treatment. Journal of Hepatology 50:5, pages 1010-1018.
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Diego A. Chiappetta, Ángel M. Carcaboso, Carlos Bregni, Modesto Rubio, Guillermo Bramuglia & Alejandro Sosnik. (2009) Indinavir-Loaded pH-Sensitive Microparticles for Taste Masking: Toward Extemporaneous Pediatric Anti-HIV/AIDS Liquid Formulations with Improved Patient Compliance. AAPS PharmSciTech 10:1, pages 1-6.
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Christoph Boesecke & David A Cooper. (2008) Toxicity of HIV protease inhibitors: clinical considerations. Current Opinion in HIV and AIDS 3:6, pages 653-659.
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A.K. Tanon, S.P. Eholié, S. Polneau, O. Kra, F. Ello, E. Ehui, E. Aoussi, A. Djadji, A. Kakou, E. Bissagnéné & A. Kadio. (2008) Efavirenz versus indinavir chez les patients naïfs infectés par le VIH-1 à Abidjan (Côte d’Ivoire). Médecine et Maladies Infectieuses 38:5, pages 264-269.
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