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Drug Evaluation

Arsenic trioxide

, MD
Pages 1773-1785 | Published online: 21 Jun 2008

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Massimo Breccia & Francesco Lo-Coco. (2012) Arsenic trioxide for management of acute promyelocytic leukemia: current evidence on its role in front-line therapy and recurrent disease. Expert Opinion on Pharmacotherapy 13:7, pages 1031-1043.
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Massimo Breccia & Francesco Lo-Coco. (2011) Gemtuzumab ozogamicin for the treatment of acute promyelocytic leukemia: mechanisms of action and resistance, safety and efficacy. Expert Opinion on Biological Therapy 11:2, pages 225-234.
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Felicetto Ferrara. (2010) Acute promyelocytic leukemia: what are the treatment options?. Expert Opinion on Pharmacotherapy 11:4, pages 587-596.
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Xp Sun, X Zhang, C He, H Qiao, X Jiang, H Jiang & X Sun. (2012) ABT-737 Synergizes with Arsenic Trioxide to Induce Apoptosis of Gastric Carcinoma Cells In Vitro and In Vivo . Journal of International Medical Research 40:4, pages 1251-1264.
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Yong Ma, Chi Zhang, Xiaoning Chen, Hongchi Jiang, Shangha Pan, Allan J. Easteal & Xueying Sun. (2012) The Influence of Modified Pluronic F127 Copolymers with Higher Phase Transition Temperature on Arsenic Trioxide-Releasing Properties and Toxicity in a Subcutaneous Model of Rats. AAPS PharmSciTech 13:2, pages 441-447.
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M. Stępnik, M. Ferlińska, A. Smok-Pieniążek, D. Gradecka-Meesters, J. Arkusz & M. Stańczyk. (2011) Assessment of the involvement of oxidative stress and Mitogen-Activated Protein Kinase signaling pathways in the cytotoxic effects of arsenic trioxide and its combination with sulindac or its metabolites: sulindac sulfide and sulindac sulfone on human leukemic cell lines. Medical Oncology 29:2, pages 1161-1172.
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Cynthia Demicheli, Frédéric Frézard, Fernanda A. Pereira, Daniel M. Santos, John B. Mangrum & Nicholas P. Farrell. (2011) Interaction of arsenite with a zinc finger CCHC peptide: Evidence for formation of an As–Zn-peptide mixed complex. Journal of Inorganic Biochemistry 105:12, pages 1753-1758.
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Maciej Stępnik, Magdalena Ferlińska, Anna Smok-Pieniążek, Dobrosława Gradecka-Meesters, Joanna Arkusz & Małgorzata Stańczyk. (2011) Sulindac and its metabolites: Sulindac sulfide and sulindac sulfone enhance cytotoxic effects of arsenic trioxide on leukemic cell lines. Toxicology in Vitro 25:5, pages 1075-1084.
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Susana M. Quintal, Queite Antonia dePaula & Nicholas P. Farrell. (2011) Zinc finger proteins as templates for metal ion exchange and ligand reactivity. Chemical and biological consequences. Metallomics 3:2, pages 121.
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Dalong Wu, Xiaowei He & Chengwen Zhang. (2010) Establishment of an arsenic-resistant human gallbladder carcinoma cell line and analysis of the differential expressions of genes associated with apoptosis. The Chinese-German Journal of Clinical Oncology 9:2, pages 86-88.
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Ming Gao, Wen Dong, Meiru Hu, Ming Yu, Liang Guo, Lu Qian, Ning Guo & Lun Song. (2010) GADD45α mediates arsenite-induced cell apoptotic effect in human hepatoma cells via JNKs/AP-1-dependent pathway. Journal of Cellular Biochemistry, pages n/a-n/a.
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B. Hernández-Castro, L. M. Doníz-Padilla, M. Salgado-Bustamante, D. Rocha, M. D. Ortiz-Pérez, M. E. Jiménez-Capdeville, D. P. Portales-Pérez, A. Quintanar-Stephano & R. González-Amaro. (2009) Effect of Arsenic on Regulatory T Cells. Journal of Clinical Immunology 29:4, pages 461-469.
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Xiaozhong Yu, Joshua F. Robinson, Elizabeth Gribble, Sung Woo Hong, Jaspreet S. Sidhu & Elaine M. Faustman. (2008) Gene expression profiling analysis reveals arsenic-induced cell cycle arrest and apoptosis in p53-proficient and p53-deficient cells through differential gene pathways. Toxicology and Applied Pharmacology 233:3, pages 389-403.
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