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Review

Selective progesterone receptor modulators 3: use in oncology, endocrinology and psychiatry

, MD PhD FACOG(hon) FRCOG(ad eundem) Hon Sen(Szeged), , MD PhD & , MD PhD
Pages 2487-2496 | Published online: 08 Sep 2008

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (3)

Giuseppe Benagiano, Carlo Bastianelli, Manuela Farris & Ivo Brosens. (2014) Selective progesterone receptor modulators: an update. Expert Opinion on Pharmacotherapy 15:10, pages 1403-1415.
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Edgar G Durán-Pérez, Oscar T Moreno-Loza, German Carrasco-Tobón & Antonio Segovia-Palomo. (2012) Optimal management of Cushing syndrome. Research and Reports in Endocrine Disorders 2, pages 19-30.
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Annie Im & Leonard J Appleman. (2010) Mifepristone: pharmacology and clinical impact in reproductive medicine, endocrinology and oncology. Expert Opinion on Pharmacotherapy 11:3, pages 481-488.
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Articles from other publishers (17)

Carolyn L. Westhoff, Hua Guo, Zhong Wang, Hanina Hibshoosh, Margaret Polaneczky, Malcolm C. Pike & Richard Ha. (2022) The progesterone-receptor modulator, ulipristal acetate, drastically lowers breast cell proliferation. Breast Cancer Research and Treatment 192:2, pages 321-329.
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Kanchan Vishnoi, Navin Viswakarma, Ajay Rana & Basabi Rana. (2020) Transcription Factors in Cancer Development and Therapy. Cancers 12:8, pages 2296.
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Hareesh B. Nair, Bindu Santhamma, Kalarickal V. Dileep, Peter Binkley, Kirk Acosta, Kam Y. J. Zhang, Robert Schenken & Klaus Nickisch. (2019) EC313-a tissue selective SPRM reduces the growth and proliferation of uterine fibroids in a human uterine fibroid tissue xenograft model. Scientific Reports 9:1.
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Alicia A Goyeneche & Carlos M Telleria. (2015) Antiprogestins in gynecological diseases. REPRODUCTION 149:1, pages R15-R33.
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Susana Cunha, Lurdes Gano, Goreti Ribeiro Morais, Thies Thiemann & Maria Cristina Oliveira. (2013) Progesterone receptor targeting with radiolabelled steroids: An approach in predicting breast cancer response to therapy. The Journal of Steroid Biochemistry and Molecular Biology 137, pages 223-241.
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Stacy L. WempeCarlos D. Gamarra-LuquesCarlos M. Telleria. (2013) Synergistic Lethality of Mifepristone and LY294002 in Ovarian Cancer Cells. Cancer Growth and Metastasis 6, pages CGM.S11124.
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Claudia Lanari, Victoria Wargon, Paola Rojas & Alfredo A Molinolo. (2012) Antiprogestins in breast cancer treatment: are we ready?. Endocrine-Related Cancer 19:3, pages R35-R50.
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Scott J. Lusher, Hans C.A. Raaijmakers, Diep Vu-Pham, Bert Kazemier, Rolien Bosch, Ross McGuire, Rita Azevedo, Hans Hamersma, Koen Dechering, Arthur Oubrie, Marcel van Duin & Jacob de Vlieg. (2012) X-ray Structures of Progesterone Receptor Ligand Binding Domain in Its Agonist State Reveal Differing Mechanisms for Mixed Profiles of 11β-Substituted Steroids. Journal of Biological Chemistry 287:24, pages 20333-20343.
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Chunyu Wang & Powel H. Brown. 2012. Genetically Engineered Mice for Cancer Research. Genetically Engineered Mice for Cancer Research 497 526 .
Chelsea R Tieszen, Alicia A Goyeneche, BreeAnn N Brandhagen, Casey T Ortbahn & Carlos M Telleria. (2011) Antiprogestin mifepristone inhibits the growth of cancer cells of reproductive and non-reproductive origin regardless of progesterone receptor expression. BMC Cancer 11:1.
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Philippe Bouchard, Nathalie Chabbert-Buffet & Bart C.J.M. Fauser. (2011) Selective progesterone receptor modulators in reproductive medicine: pharmacology, clinical efficacy and safety. Fertility and Sterility 96:5, pages 1175-1189.
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Scott J. Lusher, Hans C.A. Raaijmakers, Diep Vu-Pham, Koen Dechering, Tsang Wai Lam, Angus R. Brown, Niall M. Hamilton, Olaf Nimz, Rolien Bosch, Ross McGuire, Arthur Oubrie & Jacob de Vlieg. (2011) Structural Basis for Agonism and Antagonism for a Set of Chemically Related Progesterone Receptor Modulators. Journal of Biological Chemistry 286:40, pages 35079-35086.
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Ethan H. Beckley, Angela C. Scibelli & Deborah A. Finn. (2011) Progesterone receptor antagonist CDB-4124 increases depression-like behavior in mice without affecting locomotor ability. Psychoneuroendocrinology 36:6, pages 824-833.
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Xia Luo, Ping Yin, John S. Coon V.You-Hong Cheng, Ronald D. Wiehle & Serdar E. Bulun. (2010) The selective progesterone receptor modulator CDB4124 inhibits proliferation and induces apoptosis in uterine leiomyoma cells. Fertility and Sterility 93:8, pages 2668-2673.
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Hai-Bing Zhou, Jae Hak Lee, Christopher G. Mayne, Kathryn E. Carlson & John A. Katzenellenbogen. (2010) Imaging Progesterone Receptor in Breast Tumors: Synthesis and Receptor Binding Affinity of Fluoroalkyl-Substituted Analogues of Tanaproget. Journal of Medicinal Chemistry 53:8, pages 3349-3360.
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Julia Wilkens & Hilary Critchley. (2010) Progesterone receptor modulators in gynaecological practice. Journal of Family Planning and Reproductive Health Care 36:2, pages 87-92.
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Roisin O'Cearbhaill, Qin Zhou, Alexia Iasonos, Robert A. Soslow, Mario. M. Leitao, Carol Aghajanian & Martee L. Hensley. (2010) Treatment of advanced uterine leiomyosarcoma with aromatase inhibitors. Gynecologic Oncology 116:3, pages 424-429.
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