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Expert Opinion on Biological Therapy Volume 10, 2010 - Issue 4
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Drug Evaluations

The use of ustekinumab in autoimmune disease

Caitriona Ryan Baylor Research Institute, Department of Dermatology, 3900 Junius Street, Suite 1125, Dallas, Texas 75204, USA +1 001 469 321 6764; +1 001 214 820 9172; [email protected]
, MB BCh BAO (Hons) BMedSc (Hons),
Breck Thrash Baylor Research Institute, Department of Dermatology, 3900 Junius Street, Suite 1125, Dallas, Texas 75204, USA
, MD,
Richard B Warren University of Manchester, Salford Royal Hospital, Manchester Academic Health Science Centre, Dermatological Sciences, Manchester, M6 8HD, UK
, BSc (Hons) MBChB (Hons) PhD &
Alan Menter Baylor Research Institute, Department of Dermatology, 3900 Junius Street, Suite 1125, Dallas, Texas 75204, USA
, MD
Pages 587-604 | Published online: 11 Mar 2010

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Fabio Salvatore Macaluso, Walter Fries, Anna Viola, Giuseppe Costantino, Marco Muscianisi, Maria Cappello, Laura Guida, Enrica Giuffrida, Antonio Magnano, Dario Pluchino, Concetta Ferracane, Giovanni Magrì, Roberto Di Mitri, Filippo Mocciaro, Antonino Carlo Privitera, Salvatore Camilleri, Serena Garufi, Sara Renna, Angelo Casà, Barbara Scrivo, Marco Ventimiglia & Ambrogio Orlando. (2020) Effectiveness of Ustekinumab on Crohn‘s Disease Associated Spondyloarthropathy: Real-World Data from the Sicilian Network for Inflammatory Bowel Diseases (SN-IBD). Expert Opinion on Biological Therapy 20:11, pages 1381-1384.
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Livia Biancone, Sandro Ardizzone, Alessandro Armuzzi, Fabiana Castiglione, Renata D’Incà, Silvio Danese, Marco Daperno, Paolo Gionchetti, Fernando Rizzello, Maria Lia Scribano, Maurizio Vecchi & Ambrogio Orlando. (2020) Ustekinumab for treating ulcerative colitis: an expert opinion. Expert Opinion on Biological Therapy 20:11, pages 1321-1329.
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Fabio Salvatore Macaluso, Ambrogio Orlando & Mario Cottone. (2019) Anti-interleukin-12 and anti-interleukin-23 agents in Crohn’s disease. Expert Opinion on Biological Therapy 19:2, pages 89-98.
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Mauro Alaibac. (2019) Biological therapy of autoimmune blistering diseases. Expert Opinion on Biological Therapy 19:2, pages 149-156.
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Parakkal Deepak & Edward V Loftus$suffix/text()$suffix/text(). (2016) Ustekinumab in treatment of Crohn’s disease: design, development, and potential place in therapy. Drug Design, Development and Therapy 10, pages 3685-3698.
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Christopher B Hansen & Jeffrey P Callen. (2015) Current and future treatment options for cutaneous lupus erythematosus. Expert Opinion on Orphan Drugs 3:7, pages 777-786.
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Emanuele D’Amico, Cinzia Caserta & Francesco Patti. (2015) Monoclonal antibody therapy in multiple sclerosis: critical appraisal and new perspectives. Expert Review of Neurotherapeutics 15:3, pages 251-268.
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Alireza Minagar, Amir H Maghzi, Jeanie C McGee & J Steven Alexander. (2012) Emerging roles of endothelial cells in multiple sclerosis pathophysiology and therapy. Neurological Research 34:8, pages 738-745.
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Philip M Laws & Richard B Warren. (2011) Ustekinumab for the treatment of psoriasis. Expert Review of Clinical Immunology 7:2, pages 155-164.
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Andrew J Leishman, Gary P Sims, Matthew Sleeman & Martin Braddock. (2011) Emerging small molecule and biological therapeutic approaches for the treatment of autoimmunity. Expert Opinion on Investigational Drugs 20:1, pages 23-39.
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Articles from other publishers (28)

Greg Cantin, Qian Liu, Bhavana Shah, Scott Kuhns, Mats Wikström, Shawn Cao & Jennifer Liu. (2023) Analytical and Functional Similarity of the Biosimilar Candidate ABP 654 to Ustekinumab Reference Product. Drugs in R&D 23:4, pages 421-438.
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Vincent Chow, Daniel T. Mytych, Shyamal Das & Janet Franklin. (2023) Pharmacokinetic Similarity of ABP 654, an Ustekinumab Biosimilar Candidate: Results from a Randomized, Double‐blind Study in Healthy Subjects. Clinical Pharmacology in Drug Development.
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Andrea S. Kreienbuehl & Luc Biedermann. (2023) Morbus Crohn UpdateMaladie de Crohn – une mise à jourMorbo di Crohn – un aggiornamento. Schweizer Gastroenterologie 4:2, pages 48-63.
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Ferdinando D’Amico, Laurent Peyrin-Biroulet & Silvio Danese. (2022) Ustekinumab in Crohn’s Disease: New Data for Positioning in Treatment Algorithm. Journal of Crohn's and Colitis 16:Supplement_2, pages ii30-ii41.
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Zhigang Wang, Bram Verstockt, João Sabino, Séverine Vermeire, Marc Ferrante, Paul Declerck & Erwin Dreesen. (2021) Population pharmacokinetic‐pharmacodynamic model‐based exploration of alternative ustekinumab dosage regimens for patients with Crohn's disease. British Journal of Clinical Pharmacology 88:1, pages 323-335.
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Lucas Guillo, Ferdinando D’Amico, Silvio Danese & Laurent Peyrin-Biroulet. (2021) Ustekinumab for Extra-intestinal Manifestations of Inflammatory Bowel Disease: A Systematic Literature Review. Journal of Crohn's and Colitis 15:7, pages 1236-1243.
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James R. Burke, Lihong ChengKathleen M. GilloolyJoann StrnadAdriana Zupa-Fernandez, Ian M. Catlett, Yifan ZhangElizabeth M. Heimrich, Kim W. McIntyre, Mark D. Cunningham, Julie A. Carman, Xiadi ZhouDana Banas, Charu ChaudhrySha LiCelia D’ArienzoAnjaneya ChimalakondaXiaoXia YangJenny H. Xie, Jian PangQihong ZhaoShawn M. RoseJinwen HuangRyan M. Moslin, Stephen T. Wrobleski, David S. Weinstein & Luisa M. Salter-Cid. (2019) Autoimmune pathways in mice and humans are blocked by pharmacological stabilization of the TYK2 pseudokinase domain. Science Translational Medicine 11:502.
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Marjorie C. Argollo, Mariangela Allocca, Federica Furfaro, Laurent Peyrin-Biroulet & Silvio Danese. (2019) Interleukin-23 Blockers: Born to be First-line Biologic Agents in Inflammatory Bowel Disease?. Current Pharmaceutical Design 25:1, pages 25-31.
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Alessandro Armuzzi, Sandro Ardizzone, Livia Biancone, Fabiana Castiglione, Silvio Danese, Paolo Gionchetti, Ambrogio Orlando, Fernando Rizzello, Maria Lia Scribano, Maurizio Vecchi & Marco Daperno. (2018) Ustekinumab in the management of Crohn’s disease: Expert opinion. Digestive and Liver Disease 50:7, pages 653-660.
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Marjorie Argollo, Gionata Fiorino, Pieter Hindryckx, Laurent Peyrin-Biroulet & Silvio Danese. (2017) Novel therapeutic targets for inflammatory bowel disease. Journal of Autoimmunity 85, pages 103-116.
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Parakkal Deepak & William J. Sandborn. (2017) Ustekinumab and Anti-Interleukin-23 Agents in Crohn's Disease. Gastroenterology Clinics of North America 46:3, pages 603-626.
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J. Winny Yun, Alireza Minagar & J. Steven Alexander. 2017. Inflammatory Disorders of the Nervous System. Inflammatory Disorders of the Nervous System 1 23 .
Johnny Ludvigsson. 2017. Research into Childhood-Onset Diabetes. Research into Childhood-Onset Diabetes 21 38 .
Galen Leung, Marianna Papademetriou, Shannon Chang, Francis Arena & Seymour Katz. (2016) Interactions Between Inflammatory Bowel Disease Drugs and Chemotherapy. Current Treatment Options in Gastroenterology 14:4, pages 507-534.
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Reena Khanna, Nilesh Chande, Séverine Vermeire, William J. Sandborn, Claire E. Parker & Brian G. Feagan. (2016) The Next Wave of Biological Agents for the Treatment of IBD. Inflammatory Bowel Diseases 22:7, pages 1737-1743.
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Firas Rinawi, Yoram Rosenbach, Amit Assa & Raanan Shamir. (2016) Ustekinumab for Resistant Pediatric Crohn Disease. Journal of Pediatric Gastroenterology & Nutrition 62:4, pages e34-e35.
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Staley A. Brod. (2016) Ingested (oral) anti-IL-12/23 inhibits EAE. Journal of the Neurological Sciences 361, pages 19-25.
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Richard M. Ransohoff, David A. Hafler & Claudia F. Lucchinetti. (2015) Multiple sclerosis—a quiet revolution. Nature Reviews Neurology 11:3, pages 134-142.
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Zenas ZN YiuRichard B Warren. (2015) Efficacy and safety of emerging immunotherapies in psoriasis. Immunotherapy 7:2, pages 119-133.
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Wei Guo, Cheng Luo, Chen Wang, Yu heng Wang, Xin Wang, Xiang dong Gao & Wen Bing Yao. (2014) Suppression of human and mouse Th17 differentiation and autoimmunity by an endogenous Interleukin 23 receptor cytokine-binding homology region. The International Journal of Biochemistry & Cell Biology 55, pages 304-310.
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Daniel N. Clark, Jillian L. Markham, Chad S. Sloan & Brian D. Poole. (2013) Cytokine inhibition as a strategy for treating systemic lupus erythematosus. Clinical Immunology 148:3, pages 335-343.
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Reena Khanna & Brian G Feagan. (2013) Ustekinumab for the treatment of Crohn’s disease. Immunotherapy 5:8, pages 803-815.
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A. de Souza, T. Ali-Shaw, S.M. Reddy, D. Fiorentino & B.E. Strober. (2013) Inflammatory arthritis following ustekinumab treatment for psoriasis: a report of two cases. British Journal of Dermatology 168:1, pages 210-212.
Crossref
R. Rivera & F. Vanaclocha. (2012) Ustekinumab en situaciones especiales: embarazo, interrupciones temporales (vacunaciones, cirugía) y otros. Actas Dermo-Sifiliográficas 103, pages 45-51.
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Farida Abadja, Bara Sarraj & Mohammed J. Ansari. (2012) Significance of T helper 17 immunity in transplantation. Current Opinion in Organ Transplantation 17:1, pages 8-14.
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Pascale Quatresooz, Trinh Hermanns-Lê, Gérald E. Piérard, Philippe Humbert, Philippe Delvenne & Claudine Piérard-Franchimont. (2012) Ustekinumab in Psoriasis Immunopathology with Emphasis on the Th17-IL23 Axis: A Primer. Journal of Biomedicine and Biotechnology 2012, pages 1-5.
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T. Burnouf. (2011) Recombinant plasma proteins. Vox Sanguinis 100:1, pages 68-83.
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Johnny Ludvigsson. (2010) Immune Intervention in Children with Type 1 Diabetes. Current Diabetes Reports 10:5, pages 370-379.
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