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Review

Bacterial ghosts as carrier and targeting systems

Pages 765-771 | Published online: 23 Feb 2005

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (6)

Songwe Fanuel, Saeideh Tabesh, Huda Fatima Rajani, Sahel Heidari, Esmaeil Sadroddiny & Gholam Ali Kardar. (2017) Decorating and loading ghosts with allergens for allergen immunotherapy. Human Vaccines & Immunotherapeutics 13:10, pages 2428-2433.
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Abbas Muhammad, Jonathan Champeimont, Ulrike Beate Mayr, Werner Lubitz & Pavol Kudela. (2012) Bacterial ghosts as carriers of protein subunit and DNA-encoded antigens for vaccine applications. Expert Review of Vaccines 11:1, pages 97-116.
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Timo Langemann, Verena Juliana Koller, Abbas Muhammad, Pavol Kudela, Ulrike Beate Mayr & Werner Lubitz. (2010) The bacterial ghost platform system. Bioengineered Bugs 1:5, pages 326-336.
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Eva M Riedmann, Jennelle M Kyd, Allan W Cripps & Werner Lubitz. (2007) Bacterial ghosts as adjuvant particles. Expert Review of Vaccines 6:2, pages 241-253.
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Susanne Paukner, Thomas Stiedl, Pavol Kudela, Jozef Bizik, Firas Al Laham & Werner Lubitz. (2006) Bacterial ghosts as a novel advanced targeting system for drug and DNA delivery. Expert Opinion on Drug Delivery 3:1, pages 11-22.
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Susanne Paukner, Gudrun Kohl, Katri Jalava & Werner Lubitz. (2003) Sealed Bacterial Ghosts—Novel Targeting Vehicles for Advanced Drug Delivery of Water-soluble Substances. Journal of Drug Targeting 11:3, pages 151-161.
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Articles from other publishers (29)

Sameh Rabea, Aymen S. Yassin, Aly Fahmy Mohammed, Mounir M. Salem-Bekhit, Fars K. Alanazi, Eman Amin Esmail, Nayera A. Moneib & Abd Elgawad M. Hashem. (2022) Immunological characterization of the chemically prepared ghosts of Salmonella Typhimurium as a vaccine candidate. BMC Veterinary Research 18:1.
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Jiangang Hu, Jiakun Zuo, Zhaoguo Chen, Lixia Fu, Xiaolong Lv, Shijun Hu, Xingchi Shi, Yawei Jing, Yalei Wang, Zhihao Wang, Rongsheng Mi, Yan Huang, Dahai Liu, Kezong Qi & Xiangan Han. (2019) Use of a modified bacterial ghost lysis system for the construction of an inactivated avian pathogenic Escherichia coli vaccine candidate. Veterinary Microbiology 229, pages 48-58.
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Rui Hou, Muzi Li, Tingting Tang, Ruichong Wang, Yijing Li, Yigang Xu, Lijie Tang, Li Wang, Min Liu, Yanping Jiang, Wen Cui & Xinyuan Qiao. (2018) Construction of Lactobacillus casei ghosts by Holin-mediated inactivation and the potential as a safe and effective vehicle for the delivery of DNA vaccines. BMC Microbiology 18:1.
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Abdulaziz Abdullah Alsuwyeh, Fars Alanazi, Faiyaz Shakeel, Mounir M. Salem-Bekhit & Nazrul Haq. (2017) Estimation of Anti-neoplastic Drug Doxorubicin in Bacterial Ghost Matrix by New “Environmentally Benign” RP-HPLC Method: A Step Towards Sustainable Development of Pharmaceutical Industry. Arabian Journal for Science and Engineering 43:1, pages 181-190.
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Boram Kim, Gayeon Won & John Hwa Lee. (2017) Construction of an inactivated typhoid vaccine candidate expressing Escherichia coli heat-labile enterotoxin B subunit and evaluation of its immunogenicity in a murine model. Journal of Medical Microbiology 66:8, pages 1235-1243.
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Gayeon Won, Boram Kim & John Hwa Lee. (2017) A novel approach for construction of an inactivated typhoid vaccine candidate that effectively augments both humoral and cellular immune responses. Vaccine 35:25, pages 3333-3341.
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Gayeon Won, Tae Hoon Kim & John Hwa Lee. (2017) A novel Salmonella strain inactivated by a regulated autolysis system and expressing the B subunit of Shiga toxin 2e efficiently elicits immune responses and confers protection against virulent Stx2e-producing Escherichia coli. BMC Veterinary Research 13:1.
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Abdullah M.E. Youssof, Mounir M. Salem-Bekhit, Faiyaz Shakeel, Fars K. Alanazi & Nazrul Haq. (2016) Analysis of anti-neoplastic drug in bacterial ghost matrix, w/o/w double nanoemulsion and w/o nanoemulsion by a validated ‘green’ liquid chromatographic method. Talanta 154, pages 292-298.
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M.R. Miri, A. Behzad-Behbahani, M. Fardaei, A. Farhadi, Y. Talebkhan, M. Mohammadi, M. Tayebinia, F. Farokhinejad, P. Alavi, M. Fanian, F. Zare, J. Saberzade, N. Nikouyan, M.A. Okhovat, R. Ranjbaran, G. Rafiei Dehbidi & S. Naderi. (2015) Construction of bacterial ghosts for transfer and expression of a chimeric hepatitis C virus gene in macrophages. Journal of Microbiological Methods 119, pages 228-232.
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Jiansen Chen, Neng Li & Feifei She. (2014) Helicobacter pylori outer inflammatory protein DNA vaccine-loaded bacterial ghost enhances immune protective efficacy in C57BL/6 mice. Vaccine 32:46, pages 6054-6060.
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Chao Wang, Xiaoqi Sun, Liang Cheng, Shengnan Yin, Guangbao Yang, Yonggang Li & Zhuang Liu. (2014) Multifunctional Theranostic Red Blood Cells For Magnetic-Field-Enhanced in vivo Combination Therapy of Cancer. Advanced Materials 26:28, pages 4794-4802.
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Christian Lautenschläger, Carsten Schmidt, Dagmar Fischer & Andreas Stallmach. (2014) Drug delivery strategies in the therapy of inflammatory bowel disease. Advanced Drug Delivery Reviews 71, pages 58-76.
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Carmen Gutiérrez Millán, Clara Isabel Colino Gandarillas, María Luisa Sayalero Marinero & José M Lanao. (2012) Cell-based drug-delivery platforms. Therapeutic Delivery 3:1, pages 25-41.
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Pavol Kudela, Verena Juliana Koller & Werner Lubitz. (2010) Bacterial ghosts (BGs)?Advanced antigen and drug delivery system. Vaccine 28:36, pages 5760-5767.
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Mahendrasingh Ramjeet, Vincent Deslandes, Julien Gouré & Mario Jacques. (2008) Actinobacillus pleuropneumoniae vaccines: from bacterins to new insights into vaccination strategies . Animal Health Research Reviews 9:1, pages 25-45.
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Pavol Kudela, Susanne Paukner, Ulrike Beate Mayr, Dana Cholujova, Gudrun Kohl, Zuzana Schwarczova, Jozef Bizik, Jan Sedlak & Werner Lubitz. (2008) Effective gene transfer to melanoma cells using bacterial ghosts. Cancer Letters 262:1, pages 54-63.
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Norbert Suttorp, Tobias Welte & Reinhard MarrePablo D. Becker & Carlos A. Guzmán. 2007. Community-Acquired Pneumonia. Community-Acquired Pneumonia 201 245 .
Thomas Ebensen, Claudia Link & Carlos A. Guzm��n. 2006. Encyclopedia of Molecular Cell Biology and Molecular Medicine. Encyclopedia of Molecular Cell Biology and Molecular Medicine.
Vito G. DelVecchio, Joseph P. Connolly, Timothy G. Alefantis, Alexander Walz, Marian A. Quan, Guy Patra, John M. Ashton, Jessica T. Whittington, Ryan D. Chafin, Xudong Liang, Paul Grewal, Akbar S. Khan & Cesar V. Mujer. (2006) Proteomic Profiling and Identification of Immunodominant Spore Antigens of Bacillus anthracis , Bacillus cereus , and Bacillus thuringiensis . Applied and Environmental Microbiology 72:9, pages 6355-6363.
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Joseph P. Connolly, Diego Comerci, Timothy G. Alefantis, Alexander Walz, Marian Quan, Ryan Chafin, Paul Grewal, Cesar V. Mujer, Rodolfo A. Ugalde & Vito G. DelVecchio. (2006) Proteomic analysis of Brucella abortus cell envelope and identification of immunogenic candidate proteins for vaccine development . PROTEOMICS 6:13, pages 3767-3780.
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Akbar S. Khan, Cesar V. Mujer, Timothy G. Alefantis, Joseph P. Connolly, Ulrike Beate Mayr, Petra Walcher, Werner Lubitz & Vito G. DelVecchio. (2005) Proteomics and Bioinformatics Strategies to Design Countermeasures against Infectious Threat Agents. Journal of Chemical Information and Modeling 46:1, pages 111-115.
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Isabella Schöll, George Boltz-Nitulescu & Erika Jensen-Jarolim. (2005) Review of novel particulate antigen delivery systems with special focus on treatment of type I allergy. Journal of Controlled Release 104:1, pages 1-27.
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Pavol Kudela, Susanne Paukner, Ulrike Beate Mayr, Dana Cholujova, Zuzana Schwarczova, Jan Sedlak, Jozef Bizik & Werner Lubitz. (2005) Bacterial Ghosts as Novel Efficient Targeting Vehicles for DNA Delivery to the Human Monocyte-Derived Dendritic Cells. Journal of Immunotherapy 28:2, pages 136-143.
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Susanne Paukner, Pavol Kudela, Gudrun Kohl, Tobias Schlapp, Sonja Friedrichs & Werner Lubitz. (2005) DNA-Loaded Bacterial Ghosts Efficiently Mediate Reporter Gene Transfer and Expression in Macrophages. Molecular Therapy 11:2, pages 215-223.
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Thomas Ebensen, Susanne Paukner, Claudia Link, Pavol Kudela, Carola de Domenico, Werner Lubitz & Carlos A. Guzmán. (2004) Bacterial Ghosts Are an Efficient Delivery System for DNA Vaccines. The Journal of Immunology 172:11, pages 6858-6865.
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Susanne Paukner, Gudrun Kohl & Werner Lubitz. (2004) Bacterial ghosts as novel advanced drug delivery systems: antiproliferative activity of loaded doxorubicin in human Caco-2 cells. Journal of Controlled Release 94:1, pages 63-74.
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Francis O. Eko, Tatiana Schukovskaya, E.Y. Lotzmanova, V.V. Firstova, N.V. Emalyanova, S.N. Klueva, A.L. Kravtzov, L.F. Livanova, Vladimir V. Kutyrev, Joseph U. Igietseme & Werner Lubitz. (2003) Evaluation of the protective efficacy of Vibrio cholerae ghost (VCG) candidate vaccines in rabbits. Vaccine 21:25-26, pages 3663-3674.
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Eva M Riedmann, Jennelle M Kyd, Adam M Smith, Sara Gomez-Gallego, Katri Jalava, Allan W Cripps & Werner Lubitz. (2003) Construction of recombinant S-layer proteins (rSbsA) and their expression in bacterial ghosts â a delivery system for the nontypeable Haemophilus influenzae antigen Omp26 . FEMS Immunology & Medical Microbiology 37:2-3, pages 185-192.
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Siegfried Weiss. (2003) Transfer of eukaryotic expression plasmids to mammalian hosts by attenuated Salmonella spp.. International Journal of Medical Microbiology 293:1, pages 95-106.
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