Citations (171)
Keep up to date with the latest research on this topic with citation updates for this article.
Read on this site (12)
Lorena Garcia-Castillo, Giacomo Rubini & Paola Costelli. (2023) Pharmacotherapeutic options for cancer cachexia: emerging drugs and recent approvals. Expert Opinion on Pharmacotherapy 24:9, pages 1053-1065.
Read now
Read now
Guilherme Wesley Peixoto da Fonseca, Ryosuke Sato, Maria Janieire de Nazaré Nunes Alves & Stephan von Haehling. (2023) Current advancements in pharmacotherapy for cancer cachexia. Expert Opinion on Pharmacotherapy 24:5, pages 629-639.
Read now
Read now
Clelia Madeddu, Manuela Neri, Elisabetta Sanna, Sara Oppi & Antonio Macciò. (2021) Experimental Drugs for Chemotherapy- and Cancer-Related Anemia. Journal of Experimental Pharmacology 13, pages 593-611.
Read now
Read now
Hanie Abolfathi, Mojgan Sheikhpour, Seyed Sadegh Shahraeini, Shohreh Khatami & Seyed Ali Nojoumi. (2021) Studies in lung cancer cytokine proteomics: a review. Expert Review of Proteomics 18:1, pages 49-64.
Read now
Read now
Hexiao Tang, Yuquan Bai, Gaofeng Pan, Xianguo Wang, Yanhong Wei, Zetian Yang & Jinping Zhao. (2018) Interleukin-6 and insulin-like growth factor-1 synergistically promote the progression of NSCLC. Autoimmunity 51:8, pages 399-407.
Read now
Read now
Tyvin Rich, Fengmin Zhao, Ricardo A Cruciani, David Cella, Judith Manola & Michael J Fisch. (2017) Association of fatigue and depression with circulating levels of proinflammatory cytokines and epidermal growth factor receptor ligands: a correlative study of a placebo-controlled fatigue trial. Cancer Management and Research 9, pages 1-10.
Read now
Read now
Clelia Madeddu, Giovanni Mantovani, Giulia Gramignano & Antonio Macciò. (2015) Advances in pharmacologic strategies for cancer cachexia. Expert Opinion on Pharmacotherapy 16:14, pages 2163-2177.
Read now
Read now
Joseph D Ma, Sean F Heavey, Carolyn Revta & Eric J Roeland. (2014) Novel investigational biologics for the treatment of cancer cachexia. Expert Opinion on Biological Therapy 14:8, pages 1113-1120.
Read now
Read now
Maya K Leabman, Y Gloria Meng, Robert F Kelley, Laura E DeForge, Kyra J Cowan & Suhasini Iyer. (2013) Effects of altered FcγR binding on antibody pharmacokinetics in cynomolgus monkeys. mAbs 5:6, pages 896-903.
Read now
Read now
Kazuyoshi Yanagihara, Misato Takigahira, Keichiro Mihara, Takanori Kubo, Chie Morimoto, Yasuhiro Morita, Kiyoshi Terawaki, Yasuhito Uezono & Toshio Seyama. (2013) Inhibitory Effects of Isoflavones on Tumor Growth and Cachexia in Newly Established Cachectic Mouse Models Carrying Human Stomach Cancers. Nutrition and Cancer 65:4, pages 578-589.
Read now
Read now
Yujiong Wang, Guangcun Deng, Xiaoming Liu & William C Cho. (2013) Monoclonal antibodies in lung cancer. Expert Opinion on Biological Therapy 13:2, pages 209-226.
Read now
Read now
Antonio Macciò, Clelia Madeddu & Giovanni Mantovani. (2012) Current pharmacotherapy options for cancer anorexia and cachexia. Expert Opinion on Pharmacotherapy 13:17, pages 2453-2472.
Read now
Read now
Articles from other publishers (159)
Yongfei WangZikai DongZiyi AnWeilin Jin. (2023) Cancer cachexia: Focus on cachexia factors and inter-organ communication. Chinese Medical Journal.
Crossref
Crossref
Feng-Min Zhang, Hao-Fan Wu, Han-Ping Shi, Zhen Yu & Cheng-Le Zhuang. (2023) Sarcopenia and malignancies: epidemiology, clinical classification and implications. Ageing Research Reviews 91, pages 102057.
Crossref
Crossref
Aylin Domaniku, Sevval Nur Bilgic & Serkan Kir. (2023) Muscle wasting: emerging pathways and potential drug targets. Trends in Pharmacological Sciences 44:10, pages 705-718.
Crossref
Crossref
Kenichi Nishie, Tomomi Nishie, Seiichi Sato & Masayuki Hanaoka. (2023) Update on the treatment of cancer cachexia. Drug Discovery Today 28:9, pages 103689.
Crossref
Crossref
Mohamed Labib Salem, Ismail Atia & Nehal M. Elmashad. (2023) Higher cytotoxic activities of CD8+ T cells and natural killer cells from peripheral blood of early diagnosed lung cancer patients. BMC Immunology 24:1.
Crossref
Crossref
Sevval Nur Bilgic, Aylin Domaniku, Batu Toledo, Samet Agca, Bahar Z. C. Weber, Dilsad H. Arabaci, Zeynep Ozornek, Pascale Lause, Jean-Paul Thissen, Audrey Loumaye & Serkan Kir. (2023) EDA2R–NIK signalling promotes muscle atrophy linked to cancer cachexia. Nature 617:7962, pages 827-834.
Crossref
Crossref
Tania Setiawan, Ita Novita Sari, Yoseph Toni Wijaya, Nadya Marcelina Julianto, Jabir Aliyu Muhammad, Hyeok Lee, Ji Heon Chae & Hyog Young Kwon. (2023) Cancer cachexia: molecular mechanisms and treatment strategies. Journal of Hematology & Oncology 16:1.
Crossref
Crossref
Andrea Dalbeni, Leonardo Antonio Natola, Marta Garbin, Mirko Zoncapè, Filippo Cattazzo, Anna Mantovani, Antonio Vella, Stefania Canè, Jasmin Kassem, Michele Bevilacqua, Simone Conci, Tommaso Campagnaro, Andrea Ruzzenente, Alessandra Auriemma, Alessandro Drudi, Giovanna Zanoni, Alfredo Guglielmi, Michele Milella & David Sacerdoti. (2023) Interleukin-6: A New Marker of Advanced-Sarcopenic HCC Cirrhotic Patients. Cancers 15:9, pages 2406.
Crossref
Crossref
Josep M. Argilés, Francisco J. López-Soriano, Britta Stemmler & Silvia Busquets. (2023) Cancer-associated cachexia — understanding the tumour macroenvironment and microenvironment to improve management. Nature Reviews Clinical Oncology 20:4, pages 250-264.
Crossref
Crossref
Hai-Ting Tang, Yong-Ping Zhang, Shuai Zhao & Cai Song. (2023) Common mechanisms involved in lung cancer and depression: The dominant role of interleukin-6-IDO pathway in the lung-brain axis. Journal of Affective Disorders Reports 12, pages 100580.
Crossref
Crossref
Hengliang Xu, Guangqiang Zhao, Jixing Lin, Qianwen Ye, Jia Xiang & Bing Yan. (2023) A combined preoperative red cell distribution width and carcinoembryonic antigen score contribute to prognosis prediction in stage I lung adenocarcinoma. World Journal of Surgical Oncology 21:1.
Crossref
Crossref
Isabella Pototschnig, Ursula Feiler, Clemens Diwoky, Paul W. Vesely, Thomas Rauchenwald, Margret Paar, Latifa Bakiri, Laura Pajed, Peter Hofer, Karl Kashofer, Nyamdelger Sukhbaatar, Gabriele Schoiswohl, Thomas Weichhart, Gerald Hoefler, Christoph Bock, Martin Pichler, Erwin F. Wagner, Rudolf Zechner & Martina Schweiger. (2022) Interleukin‐6 initiates muscle‐ and adipose tissue wasting in a novel C57BL/6 model of cancer‐associated cachexia. Journal of Cachexia, Sarcopenia and Muscle 14:1, pages 93-107.
Crossref
Crossref
Yasushi Shintani, Toru Kimura, Soichiro Funaki, Naoko Ose, Takashi Kanou & Eriko Fukui. (2023) Therapeutic Targeting of Cancer-Associated Fibroblasts in the Non-Small Cell Lung Cancer Tumor Microenvironment. Cancers 15:2, pages 335.
Crossref
Crossref
Leo R. Brown, Barry J. A. Laird, Stephen J. Wigmore & Richard J. E. Skipworth. (2022) Understanding Cancer Cachexia and Its Implications in Upper Gastrointestinal Cancers. Current Treatment Options in Oncology 23:12, pages 1732-1747.
Crossref
Crossref
Yong‐Fei Wang, Zi‐Yi An, Dong‐Hai Lin & Wei‐Lin Jin. (2022) Targeting cancer cachexia: Molecular mechanisms and clinical study. MedComm 3:4.
Crossref
Crossref
Tetiana Korzun, Abraham S. Moses, Jeonghwan Kim, Siddharth Patel, Canan Schumann, Peter R. Levasseur, Parham Diba, Brennan Olson, Katia Graziella De Oliveira Rebola, Mason Norgard, Youngrong Park, Ananiya A. Demessie, Yulia Eygeris, Vladislav Grigoriev, Subisha Sundaram, Tanja Pejovic, Jonathan R. Brody, Olena R. Taratula, Xinxia Zhu, Gaurav Sahay, Daniel L. Marks & Oleh Taratula. (2022) Nanoparticle‐Based Follistatin Messenger RNA Therapy for Reprogramming Metastatic Ovarian Cancer and Ameliorating Cancer‐Associated Cachexia. Small 18:44.
Crossref
Crossref
Mansur Aliyu, Fatema Tuz Zohora, Abubakar Umar Anka, Kashif Ali, Shayan Maleknia, Mohammad Saffarioun & Gholamreza Azizi. (2022) Interleukin-6 cytokine: An overview of the immune regulation, immune dysregulation, and therapeutic approach. International Immunopharmacology 111, pages 109130.
Crossref
Crossref
Vinay Kumar Rao, Dipanwita Das & Reshma Taneja. (2022) Cancer Cachexia: Signaling and Transcriptional Regulation of Muscle Catabolic Genes. Cancers 14:17, pages 4258.
Crossref
Crossref
Rita Balsano, Zita Kruize, Martina Lunardi, Annalisa Comandatore, Mara Barone, Andrea Cavazzoni, Andrea David Re Cecconi, Luca Morelli, Hanneke Wilmink, Marcello Tiseo, Ingrid Garajovà, Lia van Zuylen, Elisa Giovannetti & Rosanna Piccirillo. (2022) Transforming Growth Factor-Beta Signaling in Cancer-Induced Cachexia: From Molecular Pathways to the Clinics. Cells 11:17, pages 2671.
Crossref
Crossref
Senait Ashenafi, Amsalu Bekele, Getachew Aseffa, Wondwossen Amogne, Endale Kassa, Getachew Aderaye, Alemayehu Worku, Peter Bergman & Susanna Brighenti. (2022) Anemia Is a Strong Predictor of Wasting, Disease Severity, and Progression, in Clinical Tuberculosis (TB). Nutrients 14:16, pages 3318.
Crossref
Crossref
Bahar Zehra Camurdanoglu Weber, Dilsad H. Arabaci & Serkan Kir. (2022) Metabolic Reprogramming in Adipose Tissue During Cancer Cachexia. Frontiers in Oncology 12.
Crossref
Crossref
Erin E. Talbert & Denis C. Guttridge. (2022) Emerging signaling mediators in the anorexia–cachexia syndrome of cancer. Trends in Cancer 8:5, pages 397-403.
Crossref
Crossref
D. Robert Paval, Rebekah Patton, James McDonald, Richard J.E. Skipworth, Iain J. Gallagher & Barry J. Laird. (2022) A systematic review examining the relationship between cytokines and cachexia in incurable cancer. Journal of Cachexia, Sarcopenia and Muscle 13:2, pages 824-838.
Crossref
Crossref
Michael J. Clowers & Seyed Javad Moghaddam. (2022) Cell Type-Specific Roles of STAT3 Signaling in the Pathogenesis and Progression of K-ras Mutant Lung Adenocarcinoma. Cancers 14:7, pages 1785.
Crossref
Crossref
Sarama Saha, Praveen Kumar Singh, Partha Roy & Sham S. Kakar. (2022) Cardiac Cachexia: Unaddressed Aspect in Cancer Patients. Cells 11:6, pages 990.
Crossref
Crossref
Santosh Kumar Singh & Rajesh Singh. (2022) Cytokines and Chemokines in Cancer Cachexia and Its Long-Term Impact on COVID-19. Cells 11:3, pages 579.
Crossref
Crossref
J. E. Gilda & S. Cohen. 2022. The Systemic Effects of Advanced Cancer. The Systemic Effects of Advanced Cancer
71
95
.
Janice Miller, Michael I. Ramage & Richard J. E. Skipworth. 2022. The Systemic Effects of Advanced Cancer. The Systemic Effects of Advanced Cancer
171
192
.
Paula P. Freire, Sarah S. Cury, Letícia O. Lopes, Geysson J. Fernandez, Jianming Liu, Leonardo Nazario de Moraes, Grasieli de Oliveira, Jakeline S. Oliveira, Diogo de Moraes, Otavio Cabral-Marques, Maeli Dal-Pai-Silva, Xiaoyun Hu, Da-Zhi Wang & Robson F. Carvalho. (2021) Decreased miR-497-5p Suppresses IL-6 Induced Atrophy in Muscle Cells. Cells 10:12, pages 3527.
Crossref
Crossref
Rajeswari Raguraman, Akhil Srivastava, Anupama Munshi & Rajagopal Ramesh. (2021) Therapeutic approaches targeting molecular signaling pathways common to diabetes, lung diseases and cancer. Advanced Drug Delivery Reviews 178, pages 113918.
Crossref
Crossref
Yu-Mu Chen, Chien-Hao Lai, Chiung-Yu Lin, Yi-Hsuan Tsai, Ya-Chun Chang, Hung-Chen Chen, Chia-Cheng Tseng, Huang-Chih Chang, Kuo-Tung Huang, Yung-Che Chen, Wen-Feng Fang, Chin-Chou Wang, Tung-Ying Chao & Meng-Chih Lin. (2021) Body Mass Index, Weight Loss, and Mortality Risk in Advanced-Stage Non-Small Cell Lung Cancer Patients: A Focus on EGFR Mutation. Nutrients 13:11, pages 3761.
Crossref
Crossref
Jason Sadek, Derek T Hall, Bianca Colalillo, Amr Omer, Anne‐Marie K Tremblay, Virginie Sanguin‐Gendreau, William Muller, Sergio Di Marco, Marco Emilio Bianchi & Imed‐Eddine Gallouzi. (2021) Pharmacological or genetic inhibition of iNOS prevents cachexia‐mediated muscle wasting and its associated metabolism defects. EMBO Molecular Medicine 13:7.
Crossref
Crossref
Carly M. Knuth, Christopher Auger & Marc G. Jeschke. (2021) Burn-induced hypermetabolism and skeletal muscle dysfunction. American Journal of Physiology-Cell Physiology 321:1, pages C58-C71.
Crossref
Crossref
Zhipeng Cao, Andrew M. Scott, Nick J. Hoogenraad & Laura D. Osellame. (2021) Mediators and clinical treatment for cancer cachexia: a systematic review. JCSM Rapid Communications 4:2, pages 166-186.
Crossref
Crossref
Christine Péladeau & Jagdeep K. Sandhu. (2021) Aberrant NLRP3 Inflammasome Activation Ignites the Fire of Inflammation in Neuromuscular Diseases. International Journal of Molecular Sciences 22:11, pages 6068.
Crossref
Crossref
Thomas Siff, Parash Parajuli, Mohammed S. Razzaque & Azeddine Atfi. (2021) Cancer-Mediated Muscle Cachexia: Etiology and Clinical Management. Trends in Endocrinology & Metabolism 32:6, pages 382-402.
Crossref
Crossref
Oki Nakano, Hirokazu Kawai, Takamasa Kobayashi, Junji Kohisa, Satoshi Ikarashi, Kazunao Hayashi, Junji Yokoyama & Shuji Terai. (2021) Rapid decline in visceral adipose tissue over 1 month is associated with poor prognosis in patients with unresectable pancreatic cancer. Cancer Medicine.
Crossref
Crossref
Yonghua Li, Huan Jin, Yibing Chen, Ting Huang, Yanjun Mi & Zhengzhi Zou. (2021) Cancer cachexia: molecular mechanism and pharmacological management. Biochemical Journal 478:9, pages 1663-1688.
Crossref
Crossref
Sanjay Rao, Elias George Kikano, Daniel Arnold Smith, Ezgi Guler, Sree Harsha Tirumani & Nikhil H. Ramaiya. (2021) Unintentional weight loss: what radiologists need to know and what clinicians want to know. Abdominal Radiology 46:5, pages 2236-2250.
Crossref
Crossref
Antonio Maccio, Elisabetta Sanna, Manuela Neri, Sara Oppi & Clelia Madeddu. (2021) Cachexia as Evidence of the Mechanisms of Resistance and Tolerance during the Evolution of Cancer Disease. International Journal of Molecular Sciences 22:6, pages 2890.
Crossref
Crossref
Mohit Kwatra, Sahabuddin Ahmed, Samir Ranjan Panda, Vegi Ganga Modi Naidu & Nitika Gupta. 2021. Background and Management of Muscular Atrophy. Background and Management of Muscular Atrophy.
Linlin Chen, Hong Zhang, Mengyi Chi, Quanjun Yang & Cheng Guo. 2021. Background and Management of Muscular Atrophy. Background and Management of Muscular Atrophy.
Rebekah Patton, D. Robert Paval, James J. McDonald, Duncan Brown, Iain J. Gallagher, Richard J.E. Skipworth, Donald C. McMillan, Ross D. Dolan, Marie Fallon & Barry J.A. Laird. (2021) Relationship between cytokines and symptoms in people with incurable cancer: A systematic review. Critical Reviews in Oncology/Hematology 159, pages 103222.
Crossref
Crossref
Kaipeng Duan, Xin Gao & Dongming Zhu. (2021) The clinical relevance and mechanism of skeletal muscle wasting. Clinical Nutrition 40:1, pages 27-37.
Crossref
Crossref
Elham Alipoor, Mohammad Javad Hosseinzadeh‐Attar, Mahsa Rezaei, Shima Jazayeri & Marianne Chapman. (2020) White adipose tissue browning in critical illness: A review of the evidence, mechanisms and future perspectives. Obesity Reviews 21:12.
Crossref
Crossref
Claudia-Eveline Molocea, Foivos-Filippos Tsokanos & Stephan Herzig. (2020) Exploiting common aspects of obesity and cancer cachexia for future therapeutic strategies. Current Opinion in Pharmacology 53, pages 101-116.
Crossref
Crossref
Gurpreet K. Arora, Arun Gupta, Tong Guo, Aakash Y. Gandhi, Aaron Laine, Dorothy L. Williams, Chul Ahn, Puneeth Iyengar & Rodney E. Infante. (2020) Janus kinase inhibitors suppress cancer cachexia‐associated anorexia and adipose wasting in mice. JCSM Rapid Communications 3:2, pages 115-128.
Crossref
Crossref
Michał Wiciński, Grzegorz Liczner, Karol Cadelski, Tadeusz Kołnierzak, Magdalena Nowaczewska & Bartosz Malinowski. (2020) Anemia of Chronic Diseases: Wider Diagnostics—Better Treatment?. Nutrients 12:6, pages 1784.
Crossref
Crossref
Simonetta Ausoni, Sara Calamelli, Salvatore Saccà & Giuseppe Azzarello. (2020) How progressive cancer endangers the heart: an intriguing and underestimated problem. Cancer and Metastasis Reviews 39:2, pages 535-552.
Crossref
Crossref
Yuqing Liu, Xiao Bi, Yumei Zhang, Yingdeng Wang & Wei Ding. (2020) Mitochondrial dysfunction/NLRP3 inflammasome axis contributes to angiotensin II-induced skeletal muscle wasting via PPAR-γ. Laboratory Investigation 100:5, pages 712-726.
Crossref
Crossref
Julian Mohrherr, Iris Z. Uras, Herwig P. Moll & Emilio Casanova. (2020) STAT3: Versatile Functions in Non-Small Cell Lung Cancer. Cancers 12:5, pages 1107.
Crossref
Crossref
Wanhai Ke, Li Zhang & Yan Dai. (2020) The role of IL‐6 in immunotherapy of non‐small cell lung cancer (NSCLC) with immune‐related adverse events (irAEs). Thoracic Cancer 11:4, pages 835-839.
Crossref
Crossref
Jawed A. Siddiqui, Ramesh Pothuraju, Maneesh Jain, Surinder K. Batra & Mohd W. Nasser. (2020) Advances in cancer cachexia: Intersection between affected organs, mediators, and pharmacological interventions. Biochimica et Biophysica Acta (BBA) - Reviews on Cancer 1873:2, pages 188359.
Crossref
Crossref
Gioacchino P. Marceca, Priya Londhe & Federica Calore. (2020) Management of Cancer Cachexia: Attempting to Develop New Pharmacological Agents for New Effective Therapeutic Options. Frontiers in Oncology 10.
Crossref
Crossref
Wen Liu, Hongxing Wang, Fuxiang Bai, Lu Ding, Yanyan Huang, Changchang Lu, Siyuan Chen, Chunyang Li, Xuetian Yue, Xiaohong Liang, Chunhong Ma, Liyun Xu & Lifen Gao. (2020) IL‐6 promotes metastasis of non‐small‐cell lung cancer by up‐regulating TIM‐4 via NF‐κB. Cell Proliferation 53:3.
Crossref
Crossref
Hélène N. Daou. (2020) Exercise as an anti-inflammatory therapy for cancer cachexia: a focus on interleukin-6 regulation. American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 318:2, pages R296-R310.
Crossref
Crossref
Megan E. Rosa-Caldwell, Dennis K. Fix, Tyrone A. Washington & Nicholas P. Greene. (2020) Muscle alterations in the development and progression of cancer-induced muscle atrophy: a review. Journal of Applied Physiology 128:1, pages 25-41.
Crossref
Crossref
Satoru Okada, Masanori Shimomura, Hiroaki Tsunezuka, Satoshi Teramukai, Shunta Ishihara, Junichi Shimada & Masayoshi Inoue. (2020) Prognostic Significance of Perioperative C-Reactive Protein in Resected Non-Small Cell Lung Cancer. Seminars in Thoracic and Cardiovascular Surgery 32:4, pages 1046-1055.
Crossref
Crossref
Taylor E. Berent, Jessica M. Dorschner, Thomas Meyer, Theodore A. Craig, Xuewei Wang, Hawley Kunz, Aminah Jatoi, Ian R. Lanza, Horng Chen & Rajiv Kumar. (2019) Impaired cardiac performance, protein synthesis, and mitochondrial function in tumor-bearing mice. PLOS ONE 14:12, pages e0226440.
Crossref
Crossref
Farsad Eskandary, Michael Dürr, Klemens Budde, Konstantin Doberer, Roman Reindl-Schwaighofer, Johannes Waiser, Markus Wahrmann, Heinz Regele, Andreas Spittler, Nils Lachmann, Christa Firbas, Jakob Mühlbacher, Gregor Bond, Philipp F. Halloran, Edward Chong, Bernd Jilma & Georg A. Böhmig. (2019) Clazakizumab in late antibody-mediated rejection: study protocol of a randomized controlled pilot trial. Trials 20:1.
Crossref
Crossref
James J. McDonald, Marie T. Fallon & Barry J.A. Laird. (2019) Meaningful measures in cancer cachexia: implications for practice and research. Current Opinion in Supportive & Palliative Care 13:4, pages 323-327.
Crossref
Crossref
Hyejin Lee, Ji-Won Heo, A-Reum Kim, Minson Kweon, Sorim Nam, Jong-Seok Lim, Mi-Kyung Sung, Sung-Eun Kim & Jae-Ha Ryu. (2019) Z-ajoene from Crushed Garlic Alleviates Cancer-Induced Skeletal Muscle Atrophy. Nutrients 11:11, pages 2724.
Crossref
Crossref
Ali Maleki, Fatemeh Sayyadipour, Hamid Ahmadi, Masoud Soleimani & Fakhredin Saba. (2020) The Statue of Cytokines Therapy in Blood Transfusion Running Cytokine and Blood Transfusion. Cell and Tissue Biology 13:6, pages 407-417.
Crossref
Crossref
Duk Hwan Kim. (2019) Nutritional issues in patients with cancer. Intestinal Research 17:4, pages 455-462.
Crossref
Crossref
Ross D. Dolan, Barry J.A. Laird, Pål Klepstad, Stein Kaasa, Paul G. Horgan, Ørnulf PaulsenDonald C. McMillan. (2019) An exploratory study examining the relationship between performance status and systemic inflammation frameworks and cytokine profiles in patients with advanced cancer. Medicine 98:37, pages e17019.
Crossref
Crossref
Wenjun Hu, Zeyuan Ru, Yali Zhou, Wen Xiao, Rulin Sun, Santao Zhang, Yaoying Gao, Xiang Li, Xiaoping Zhang & Hongmei Yang. (2019) Lung cancer-derived extracellular vesicles induced myotube atrophy and adipocyte lipolysis via the extracellular IL-6-mediated STAT3 pathway. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 1864:8, pages 1091-1102.
Crossref
Crossref
Stanley M.H. Chan, Stavros Selemidis, Steven Bozinovski & Ross Vlahos. (2019) Pathobiological mechanisms underlying metabolic syndrome (MetS) in chronic obstructive pulmonary disease (COPD): clinical significance and therapeutic strategies. Pharmacology & Therapeutics 198, pages 160-188.
Crossref
Crossref
Jeong Min An, Eun A Kang, Young-Min Han, Ji Young Oh, Dong Yoon Lee, Seung Hye Choi, Duk Hwan Kim & Ki Baik Hahm. (2019) Dietary intake of probiotic kimchi ameliorated IL-6-driven cancer cachexia. Journal of Clinical Biochemistry and Nutrition 65:2, pages 109-117.
Crossref
Crossref
Ryan Clay & Shadab A. Siddiqi. 2019. Theranostic Approach for Pancreatic Cancer. Theranostic Approach for Pancreatic Cancer
325
367
.
Lakshmi Pulakat & Madhavi P. Gavini. 2019. Handbook of Famine, Starvation, and Nutrient Deprivation. Handbook of Famine, Starvation, and Nutrient Deprivation
2149
2167
.
Anastasiya Yakovenko, Miles Cameron & Jose Gilberto Trevino. (2018) Molecular therapeutic strategies targeting pancreatic cancer induced cachexia. World Journal of Gastrointestinal Surgery 10:9, pages 95-106.
Crossref
Crossref
Antonio Macciò, Silvia Busquets, Clelia Madeddu & Josep M. Argilés. (2018) Editorial: Biological Mechanism-Based and Patient-Centered Management of Cancer-Related Symptoms and Syndromes. Frontiers in Physiology 9.
Crossref
Crossref
Ya-Chin Hou, Chih-Jung Wang, Ying-Jui Chao, Hao-Yun Chen, Hao-Chen Wang, Hui-Ling Tung, Jung-Ting Lin & Yan-Shen Shan. (2018) Elevated Serum Interleukin-8 Level Correlates with Cancer-Related Cachexia and Sarcopenia: An Indicator for Pancreatic Cancer Outcomes. Journal of Clinical Medicine 7:12, pages 502.
Crossref
Crossref
Jun Han, Qingyang Meng, Lei Shen & Guohao Wu. (2018) Interleukin-6 induces fat loss in cancer cachexia by promoting white adipose tissue lipolysis and browning. Lipids in Health and Disease 17:1.
Crossref
Crossref
Simon A. Jones & Brendan J. Jenkins. (2018) Recent insights into targeting the IL-6 cytokine family in inflammatory diseases and cancer. Nature Reviews Immunology 18:12, pages 773-789.
Crossref
Crossref
Ali Masjedi, Vida Hashemi, Mohammad Hojjat-Farsangi, Ghasem Ghalamfarsa, Gholamreza Azizi, Mehdi Yousefi & Farhad Jadidi-Niaragh. (2018) The significant role of interleukin-6 and its signaling pathway in the immunopathogenesis and treatment of breast cancer. Biomedicine & Pharmacotherapy 108, pages 1415-1424.
Crossref
Crossref
Clelia Madeddu, Giulia Gramignano, Giorgio Astara, Roberto Demontis, Elisabetta Sanna, Vinicio Atzeni & Antonio Macciò. (2018) Pathogenesis and Treatment Options of Cancer Related Anemia: Perspective for a Targeted Mechanism-Based Approach. Frontiers in Physiology 9.
Crossref
Crossref
Sawsan Elattar, Manali Dimri & Ande Satyanarayana. (2018) The tumor secretory factor ZAG promotes white adipose tissue browning and energy wasting. The FASEB Journal 32:9, pages 4727-4743.
Crossref
Crossref
Moses Kasembeli, Uddalak Bharadwaj, Prema Robinson & David Tweardy. (2018) Contribution of STAT3 to Inflammatory and Fibrotic Diseases and Prospects for its Targeting for Treatment. International Journal of Molecular Sciences 19:8, pages 2299.
Crossref
Crossref
Ting Zhou & Shiying Yu. (2018) Advances in the diagnosis and treatment of patients with cancer cachexia. Oncology and Translational Medicine 4:4, pages 133-143.
Crossref
Crossref
Elaine S Rogers, William Ormiston, Rachel Heron, Beau Pontré, Roderick MacLeod & Anthony Doyle. (2018) Body composition skeletal muscle analysis in cancer cachexia studies: Is there a place for 3T MRI analysis?. JCSM Clinical Reports 3:2, pages 1-11.
Crossref
Crossref
Kriti Ray, Beata Ujvari, Venkata Ramana & John Donald. (2018) Cross-talk between EGFR and IL-6 drives oncogenic signaling and offers therapeutic opportunities in cancer. Cytokine & Growth Factor Reviews 41, pages 18-27.
Crossref
Crossref
Zvi Cramer, Jason Sadek, Gabriela Galicia Vazquez, Sergio Di Marco, Arnim Pause, Jerry Pelletier & Imed-Eddine Gallouzi. (2018) eIF4A inhibition prevents the onset of cytokine-induced muscle wasting by blocking the STAT3 and iNOS pathways. Scientific Reports 8:1.
Crossref
Crossref
Zachary C. Ryan, Theodore A. Craig, Xuewei Wang, Philippe Delmotte, Jeffrey L. Salisbury, Ian R. Lanza, Gary C. Sieck & Rajiv Kumar. (2018) 1α,25-dihydroxyvitamin D3 mitigates cancer cell mediated mitochondrial dysfunction in human skeletal muscle cells. Biochemical and Biophysical Research Communications 496:2, pages 746-752.
Crossref
Crossref
D. Brooke Widner, D. Clark Files, Kathryn E. Weaver & Yusuke Shiozawa. (2018) Preclinical and clinical studies on cancer-associated cachexia. Frontiers in Biology 13:1, pages 11-18.
Crossref
Crossref
Mingzhi Xie, Xiaoju Chen, Shouming Qin, Yongjian Bao, Kunpeng Bu & Yang Lu. (2018) Clinical study on thalidomide combined with cinobufagin to treat lung cancer cachexia. Journal of Cancer Research and Therapeutics 14:1, pages 226-232.
Crossref
Crossref
Tonya C. Walser, Elvira L. Liclican, Kenneth J. O’Byrne, William C.S. Cho & Steven M. Dubinett. 2018. IASLC Thoracic Oncology. IASLC Thoracic Oncology
121
128.e4
.
Sarra Setrerrahmane & Hanmei Xu. (2017) Tumor-related interleukins: old validated targets for new anti-cancer drug development. Molecular Cancer 16:1.
Crossref
Crossref
Audrey Loumaye & Jean-Paul Thissen. (2017) Biomarkers of cancer cachexia. Clinical Biochemistry 50:18, pages 1281-1288.
Crossref
Crossref
Emanuele Berardi. (2017) Muscular Dystrophies and Cancer Cachexia: Similarities in Chronic Skeletal Muscle Degeneration. Journal of Functional Morphology and Kinesiology 2:4, pages 39.
Crossref
Crossref
Limin Wang, Limin Cao, Huimin Wang, Boning Liu, Qicheng Zhang, Zhaowei Meng, Xiang Wu, Qinghua Zhou & Ke Xu. (2017) Cancer-associated fibroblasts enhance metastatic potential of lung cancer cells through IL-6/STAT3 signaling pathway. Oncotarget 8:44, pages 76116-76128.
Crossref
Crossref
Shi-Min An, Hui-Min Lei, Xu-Ping Ding, Fan Sun, Chun Zhang, Ya-Bin Tang, Hong-Zhuan Chen, Ying Shen & Liang Zhu. (2017) Interleukin-6 identified as an important factor in hypoxia- and aldehyde dehydrogenase-based gefitinib adaptive resistance in non-small cell lung cancer cells. Oncology Letters 14:3, pages 3445-3454.
Crossref
Crossref
Makoto Yoshimura, Yoshihiro Shiomi, Yuta Ohira, Mineo Takei & Takao Tanaka. (2017) Z-505 hydrochloride, an orally active ghrelin agonist, attenuates the progression of cancer cachexia via anabolic hormones in Colon 26 tumor-bearing mice. European Journal of Pharmacology 811, pages 30-37.
Crossref
Crossref
Michelle Guan, Arvind M. Shinde & Andrew E. Hendifar. 2017. Frailty and Sarcopenia - Onset, Development and Clinical Challenges. Frailty and Sarcopenia - Onset, Development and Clinical Challenges.
Qian Liu, Shengnan Yu, Anping Li, Hanxiao Xu, Xinwei Han & Kongming Wu. (2017) Targeting interlukin-6 to relieve immunosuppression in tumor microenvironment. Tumor Biology 39:6, pages 101042831771244.
Crossref
Crossref
Jennifer F Ma, Brenda J Sanchez, Derek T Hall, Anne‐Marie K Tremblay, Sergio Di Marco & Imed‐Eddine Gallouzi. (2017)
STAT
3 promotes
IFN
γ/
TNF
α‐induced muscle wasting in an
NF
‐κB‐dependent and
IL
‐6‐independent manner
. EMBO Molecular Medicine 9:5, pages 622-637.
Crossref
Crossref
A Miller, L McLeod, S Alhayyani, A Szczepny, D N Watkins, W Chen, P Enriori, W Ferlin, S Ruwanpura & B J Jenkins. (2016) Blockade of the IL-6 trans-signalling/STAT3 axis suppresses cachexia in Kras-induced lung adenocarcinoma. Oncogene 36:21, pages 3059-3066.
Crossref
Crossref
Takuma Tsukioka, Noritoshi Nishiyama, Nobuhiro Izumi, Shinjiro Mizuguchi, Hiroaki Komatsu, Satoshi Okada, Michihito Toda, Kantaro Hara, Ryuichi Ito & Toshihiko Shibata. (2017) Sarcopenia is a novel poor prognostic factor in male patients with pathological Stage I non-small cell lung cancer. Japanese Journal of Clinical Oncology 47:4, pages 363-368.
Crossref
Crossref
DH Yang. (2017) The Biological Effects of Interleukin-6 and Their Clinical Applications in Autoimmune Diseases and Cancers. Rheumatica Acta: Open Access 1:1, pages 006-016.
Crossref
Crossref
Jingjiao Zhou, Zhaoxia Qu, Fan Sun, Lei Han, Liwen Li, Shapei Yan, Laura P. Stabile, Lin-Feng Chen, Jill M. Siegfried & Gutian Xiao. (2017) Myeloid STAT3 Promotes Lung Tumorigenesis by Transforming Tumor Immunosurveillance into Tumor-Promoting Inflammation. Cancer Immunology Research 5:3, pages 257-268.
Crossref
Crossref
Takao Ohnuma. 2016. Holland‐Frei Cancer Medicine. Holland‐Frei Cancer Medicine
1
10
.
Hatim Husain, Michael Scur, Ayesha Murtuza, Nam Bui, Brian Woodward & Razelle Kurzrock. (2017) Strategies to Overcome Bypass Mechanisms Mediating Clinical Resistance to EGFR Tyrosine Kinase Inhibition in Lung Cancer. Molecular Cancer Therapeutics 16:2, pages 265-272.
Crossref
Crossref
Jann Arends, Patrick Bachmann, Vickie Baracos, Nicole Barthelemy, Hartmut Bertz, Federico Bozzetti, Ken Fearon, Elisabeth Hütterer, Elizabeth Isenring, Stein Kaasa, Zeljko Krznaric, Barry Laird, Maria Larsson, Alessandro Laviano, Stefan Mühlebach, Maurizio Muscaritoli, Line Oldervoll, Paula Ravasco, Tora Solheim, Florian Strasser, Marian de van der Schueren & Jean-Charles Preiser. (2017) ESPEN guidelines on nutrition in cancer patients. Clinical Nutrition 36:1, pages 11-48.
Crossref
Crossref
Ernie D. Au, Aditya P. Desai, Leonidas G. Koniaris & Teresa A. Zimmers. (2017) The MEK-Inhibitor Selumetinib Attenuates Tumor Growth and Reduces IL-6 Expression but Does Not Protect against Muscle Wasting in Lewis Lung Cancer Cachexia. Frontiers in Physiology 7.
Crossref
Crossref
Daniel Delitto, Sarah M. Judge, Andrea E. Delitto, Rachel L. Nosacka, Fernanda G. Rocha, Bayli B. DiVita, Michael H. Gerber, Thomas J. GeorgeJrJr, Kevin E. Behrns, Steven J. Hughes, Shannon M. Wallet, Andrew R. Judge & Jose G. Trevino. (2016) Human pancreatic cancer xenografts recapitulate key aspects of cancer cachexia. Oncotarget 8:1, pages 1177-1189.
Crossref
Crossref
Xin Wang, Xiaodong Yang, Ying Tsai, Li Yang, Kuang-Hsiang Chuang, Peter C. Keng, Soo Ok Lee & Yuhchyau Chen. (2017) IL-6 Mediates Macrophage Infiltration after Irradiation via Up-regulation of CCL2/CCL5 in Non-small Cell Lung Cancer. Radiation Research 187:1, pages 50-59.
Crossref
Crossref
Shizuka Kashiwagi, Mohammed A.S. Khan, Shingo Yasuhara, Takahisa Goto, William R. Kem, Ronald G. Tompkins, Masao Kaneki & J.A. Jeevendra Martyn. (2017) Prevention of Burn-Induced Inflammatory Responses and Muscle Wasting by GTS-21, a Specific Agonist for α7 Nicotinic Acetylcholine Receptors. SHOCK 47:1, pages 61-69.
Crossref
Crossref
Ng Shyh-Chang. 2017. Translational Research in Breast Cancer. Translational Research in Breast Cancer
233
249
.
Lakshmi Pulakat & Madhavi P. Gavini. 2017. Handbook of Famine, Starvation, and Nutrient Deprivation. Handbook of Famine, Starvation, and Nutrient Deprivation
1
19
.
Abhishek Saxena & Donghui Wu. (2016) Advances in Therapeutic Fc Engineering – Modulation of IgG-Associated Effector Functions and Serum Half-life. Frontiers in Immunology 7.
Crossref
Crossref
Tara C. Mueller, Jeannine Bachmann, Olga Prokopchuk, Helmut Friess & Marc E. Martignoni. (2016) Molecular pathways leading to loss of skeletal muscle mass in cancer cachexia – can findings from animal models be translated to humans?. BMC Cancer 16:1.
Crossref
Crossref
Samantha L. Passey, Michelle J. Hansen, Steven Bozinovski, Christine F. McDonald, Anne E. Holland & Ross Vlahos. (2016) Emerging therapies for the treatment of skeletal muscle wasting in chronic obstructive pulmonary disease. Pharmacology & Therapeutics 166, pages 56-70.
Crossref
Crossref
Jin Zhou, Bin Liu, Chun Liang, Yangxin Li & Yao-Hua Song. (2016) Cytokine Signaling in Skeletal Muscle Wasting. Trends in Endocrinology & Metabolism 27:5, pages 335-347.
Crossref
Crossref
Tae-Hwe Heo, Joseph Wahler & Nanjoo Suh. (2016) Potential therapeutic implications of IL-6/IL-6R/gp130-targeting agents in breast cancer. Oncotarget 7:13, pages 15460-15473.
Crossref
Crossref
Michele Petruzzelli & Erwin F. Wagner. (2016) Mechanisms of metabolic dysfunction in cancer-associated cachexia. Genes & Development 30:5, pages 489-501.
Crossref
Crossref
Gavin D. Brooks, Louise McLeod, Sultan Alhayyani, Alistair Miller, Prudence A. Russell, Walter Ferlin, Stefan Rose-John, Saleela Ruwanpura & Brendan J. Jenkins. (2016) IL6 Trans-signaling Promotes KRAS-Driven Lung Carcinogenesis. Cancer Research 76:4, pages 866-876.
Crossref
Crossref
Soo Ok Lee, Xiaodong Yang, Shanzhou Duan, Ying Tsai, Laura R. Strojny, Peter Keng & Yuhchyau Chen. (2015) IL-6 promotes growth and epithelial-mesenchymal transition of CD133+ cells of non-small cell lung cancer. Oncotarget 7:6, pages 6626-6638.
Crossref
Crossref
Shiro Kimbara & Shunsuke Kondo. (2016) Immune checkpoint and inflammation as therapeutic targets in pancreatic carcinoma. World Journal of Gastroenterology 22:33, pages 7440.
Crossref
Crossref
Jie Yuan, Fei Zhang & Ruifang Niu. (2015) Multiple regulation pathways and pivotal biological functions of STAT3 in cancer. Scientific Reports 5:1.
Crossref
Crossref
J. Compston & K.C.H. Fearon. (2015) Emerging therapeutic concepts for muscle and bone preservation/formation. Bone 80, pages 157-161.
Crossref
Crossref
Clelia Madeddu, Giovanni Mantovani, Giulia Gramignano, Giorgio Astara & Antonio Macciò. (2015) Muscle wasting as main evidence of energy impairment in cancer cachexia: future therapeutic approaches. Future Oncology 11:19, pages 2697-2710.
Crossref
Crossref
Jie Chen, Tian Lan, Weimin Zhang, Lijia Dong, Nan Kang, Shumin Zhang, Ming Fu, Bing Liu, Kangtai Liu & Qimin Zhan. (2015) Feed-Forward Reciprocal Activation of PAFR and STAT3 Regulates Epithelial–Mesenchymal Transition in Non–Small Cell Lung Cancer. Cancer Research 75:19, pages 4198-4210.
Crossref
Crossref
Tadashi Yoshida & Patrice Delafontaine. (2015) Mechanisms of Cachexia in Chronic Disease States. The American Journal of the Medical Sciences 350:4, pages 250-256.
Crossref
Crossref
Maria Carolina S Mendes, Gustavo D Pimentel, Felipe O Costa & José B C Carvalheira. (2015) Molecular and neuroendocrine mechanisms of cancer cachexia. Journal of Endocrinology 226:3, pages R29-R43.
Crossref
Crossref
Zhaoxia Qu, Fan Sun, Jingjiao Zhou, Liwen Li, Steven D. Shapiro & Gutian Xiao. (2015) Interleukin-6 Prevents the Initiation but Enhances the Progression of Lung Cancer. Cancer Research 75:16, pages 3209-3215.
Crossref
Crossref
Timo Rath, Ulrike Billmeier, Maximilian J. Waldner, Raja Atreya & Markus F. Neurath. (2015) From physiology to disease and targeted therapy: interleukin-6 in inflammation and inflammation-associated carcinogenesis. Archives of Toxicology 89:4, pages 541-554.
Crossref
Crossref
Hui Wang & Jianping Ye. (2014) Regulation of energy balance by inflammation: Common theme in physiology and pathology. Reviews in Endocrine and Metabolic Disorders 16:1, pages 47-54.
Crossref
Crossref
Shenhav Cohen, James A. Nathan & Alfred L. Goldberg. (2014) Muscle wasting in disease: molecular mechanisms and promising therapies. Nature Reviews Drug Discovery 14:1, pages 58-74.
Crossref
Crossref
Annamaria Ruzzo, Vincenzo Catalano, Emanuele Canestrari, Elisa Giacomini, Daniele Santini, Giuseppe Tonini, Bruno Vincenzi, Giammaria Fiorentini, Mauro Magnani & Francesco Graziano. (2014) Genetic modulation of the interleukin 6 (IL-6) system in patients with advanced gastric cancer: a background for an alternative target therapy. BMC Cancer 14:1.
Crossref
Crossref
Aditi A. Narsale & James A. Carson. (2014) Role of interleukin-6 in cachexia. Current Opinion in Supportive & Palliative Care 8:4, pages 321-327.
Crossref
Crossref
Martin Chasen, Ravi Bhargava & Shalom Hirschman. (2014) Immunomodulatory agents for the treatment of cachexia. Current Opinion in Supportive & Palliative Care 8:4, pages 328-333.
Crossref
Crossref
Parvin Ataie-Kachoie, Mohammad H Pourgholami, Des R Richardson & David L Morris. (2014) Gene of the month: Interleukin 6 (IL-6). Journal of Clinical Pathology 67:11, pages 932-937.
Crossref
Crossref
Marine Gilabert, Ezequiel Calvo, Ana Airoldi, Tewfik Hamidi, Vincent Moutardier, Olivier Turrini & Juan Iovanna. (2014) Pancreatic Cancer-Induced Cachexia Is Jak2-Dependent in Mice. Journal of Cellular Physiology 229:10, pages 1437-1443.
Crossref
Crossref
Frank R. Brennan. 2014. Handbook of Therapeutic Antibodies. Handbook of Therapeutic Antibodies
969
1078
.
Michele Petruzzelli, Martina Schweiger, Renate Schreiber, Ramon Campos-Olivas, Maria Tsoli, John Allen, Michael Swarbrick, Stefan Rose-John, Mercedes Rincon, Graham Robertson, Rudolf Zechner & Erwin F. Wagner. (2014) A Switch from White to Brown Fat Increases Energy Expenditure in Cancer-Associated Cachexia. Cell Metabolism 20:3, pages 433-447.
Crossref
Crossref
Reinhild Holmer, Freya A Goumas, Georg H Waetzig, Stefan Rose-John & Holger Kalthoff. (2014) Interleukin-6: a villain in the drama of pancreatic cancer development and progression. Hepatobiliary & Pancreatic Diseases International 13:4, pages 371-380.
Crossref
Crossref
Lanxi Song, Matthew A. Smith, Parul Doshi, Kate Sasser, William Fulp, Soner Altiok & Eric B. Haura. (2014) Antitumor Efficacy of the Anti-Interleukin-6 (IL-6) Antibody Siltuximab in Mouse Xenograft Models of Lung Cancer. Journal of Thoracic Oncology 9:7, pages 974-982.
Crossref
Crossref
Magdalena Tertil, Klaudia Skrzypek, Urszula Florczyk, Kazimierz Weglarczyk, Halina Was, Guillaume Collet, Alan Guichard, Tomasz Gil, Jaroslaw Kuzdzal, Alicja Jozkowicz, Claudine Kieda, Chantal Pichon & Jozef Dulak. (2014) Regulation and Novel Action of Thymidine Phosphorylase in Non-Small Cell Lung Cancer: Crosstalk with Nrf2 and HO-1. PLoS ONE 9:5, pages e97070.
Crossref
Crossref
David S Hong, David Hui, Eduardo Bruera, Filip Janku, Aung Naing, Gerald S Falchook, Sarina Piha-Paul, Jennifer J Wheler, Siqing Fu, Apostolia M Tsimberidou, Michael Stecher, Prasant Mohanty, John Simard & Razelle Kurzrock. (2014) MABp1, a first-in-class true human antibody targeting interleukin-1α in refractory cancers: an open-label, phase 1 dose-escalation and expansion study. The Lancet Oncology 15:6, pages 656-666.
Crossref
Crossref
Zhuang MaWenwu Sun. (2014) The Effect of Aerosol Polyethylenimine/Interferon-γ Plasmid Complexes on Expression of Inflammatory Cytokines in Mouse Lung. Journal of Aerosol Medicine and Pulmonary Drug Delivery 27:2, pages 117-124.
Crossref
Crossref
Xin Yao, Jiaqi Huang, Haihong Zhong, Nan Shen, Raffaella Faggioni, Michael Fung & Yihong Yao. (2014) Targeting interleukin-6 in inflammatory autoimmune diseases and cancers. Pharmacology & Therapeutics 141:2, pages 125-139.
Crossref
Crossref
Sumbul Ali & Jose M. Garcia. (2014) Sarcopenia, Cachexia and Aging: Diagnosis, Mechanisms and Therapeutic Options - A Mini-Review. Gerontology 60:4, pages 294-305.
Crossref
Crossref
Elvio G. Russi, Judith E. Raber-Durlacher & Stephen T. Sonis. (2014) Local and Systemic Pathogenesis and Consequences of Regimen-Induced Inflammatory Responses in Patients with Head and Neck Cancer Receiving Chemoradiation. Mediators of Inflammation 2014, pages 1-14.
Crossref
Crossref
B. Reeves & S.A. Bernard. 2014. Pathobiology of Human Disease. Pathobiology of Human Disease
456
466
.
Andrew B. Nixon, Herbert Pang, Mark D. Starr, Paula N. Friedman, Monica M. Bertagnolli, Hedy L. Kindler, Richard M. Goldberg, Alan P. Venook & Herbert I. Hurwitz. (2013) Prognostic and Predictive Blood-Based Biomarkers in Patients with Advanced Pancreatic Cancer: Results from CALGB80303 (Alliance). Clinical Cancer Research 19:24, pages 6957-6966.
Crossref
Crossref
Xiaohong Tan, Julian Carretero, Zhao Chen, Jishuai Zhang, Yanxiao Wang, Jicheng Chen, Xiubin Li, Hui Ye, Chuanhao Tang, Xuan Cheng, Ning Hou, Xiao Yang & Kwok-Kin Wong. (2013) Loss of p53 Attenuates the Contribution of IL-6 Deletion on Suppressed Tumor Progression and Extended Survival in Kras-Driven Murine Lung Cancer. PLoS ONE 8:11, pages e80885.
Crossref
Crossref
Takashi Morikawa, Atsuhiro Yoshida, Shinya Kobayashi, Mikiko Shibata, Masahiro Hamada, Masatsugu Kishida, Chizuko Kitabayashi, Haruko Daga, Yoshio Konishi, Koji Takeda & Masahito Imanishi. (2013) AP-VAS 2012 case report: a case of ANCA-negative pauci-immune crescentic glomerulonephritis associated with IL-6-producing adenosquamous cell carcinoma of the lung. CEN Case Reports 2:2, pages 158-164.
Crossref
Crossref
Marie Amitani, Akihiro Asakawa, Haruka Amitani & Akio Inui. (2013) Control of food intake and muscle wasting in cachexia. The International Journal of Biochemistry & Cell Biology 45:10, pages 2179-2185.
Crossref
Crossref
N. Johns, N.A. Stephens & K.C.H. Fearon. (2013) Muscle wasting in cancer. The International Journal of Biochemistry & Cell Biology 45:10, pages 2215-2229.
Crossref
Crossref
Aaron Laine, Puneeth Iyengar & Tej K. Pandita. (2013) The Role of Inflammatory Pathways in Cancer-Associated Cachexia and Radiation Resistance. Molecular Cancer Research 11:9, pages 967-972.
Crossref
Crossref
Parvin Ataie-Kachoie, Mohammad H. Pourgholami & David L. Morris. (2013) Inhibition of the IL-6 signaling pathway: A strategy to combat chronic inflammatory diseases and cancer. Cytokine & Growth Factor Reviews 24:2, pages 163-173.
Crossref
Crossref
Kenneth Fearon, Jann Arends & Vickie Baracos. (2012) Understanding the mechanisms and treatment options in cancer cachexia. Nature Reviews Clinical Oncology 10:2, pages 90-99.
Crossref
Crossref
Fabio Penna, Gabriella Bonelli, Francesco M. Baccino & Paola Costelli. 2013. Anorexia. Anorexia
271
299
.
J. Pfirstinger, A. Reichle & J. Grassinger. 2013. Evolution-adjusted Tumor Pathophysiology:. Evolution-adjusted Tumor Pathophysiology:
397
415
.
Pleun J. de Raaf, Stefan Sleijfer, Cor H.J. Lamers, Agnes Jager, Jan Willem Gratama & Carin C. D. van der Rijt. (2012) Inflammation and fatigue dimensions in advanced cancer patients and cancer survivors. Cancer 118:23, pages 6005-6011.
Crossref
Crossref
Chih-Jung Chen, Wen-Wei Sung, Yueh-Min Lin, Mu-Kuan Chen, Ching-Hsiao Lee, Huei Lee, Kun-Tu Yeh & Jiunn-Liang Ko. (2012) Gender Difference in the Prognostic Role of Interleukin 6 in Oral Squamous Cell Carcinoma. PLoS ONE 7:11, pages e50104.
Crossref
Crossref
Kenneth C.H. Fearon, David J. Glass & Denis C. Guttridge. (2012) Cancer Cachexia: Mediators, Signaling, and Metabolic Pathways. Cell Metabolism 16:2, pages 153-166.
Crossref
Crossref
L. Guilleminault, E. Lemarié & N. Heuzé-Vourc’h. (2012) Monoclonal Antibodies: An Emerging Class of Therapeutics in Non Small Cell Lung Cancer. Journal of Cancer Therapy 03:06, pages 1170-1190.
Crossref
Crossref
Egidio Del Fabbro, Akio Inui & Florian StrasserEgidio Del Fabbro, Akio Inui & Florian Strasser. 2012. Cancer Cachexia. Cancer Cachexia
73
83
.