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Expert Opinion on Biological Therapy Volume 12, 2012 - Issue sup1: Circulating nucleic acids in plasma and serum (CNAPS) update 2011
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Implementing noninvasive prenatal fetal sex determination using cell-free fetal DNA in the United Kingdom

Melissa HillInstitute of Child Health, Great Ormond Street Hospital for Children NHS Trust, Clinical and Molecular Genetics, 30 Guildford Street, London WC1N 6EH, UK+0207 905 2876; +0207 380 9984; [email protected]
,
Celine LewisGenetic Alliance UK, London, UK
,
Lucy JenkinsGreat Ormond Street Hospital for Children NHS Trust, North East Thames Regional Molecular Genetics Laboratory, London, UK
,
Stephanie AllenBirmingham Women's Hospital NHS Foundation Trust, West Midlands Regional Genetics Laboratory, Birmingham, UK
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Rob G EllesCentral Manchester University Hospitals NHS Trust, Manchester Academic Health Science Centre, Regional Genetics Laboratory Service, Genetic Medicine, Manchester, UK
&
Lyn S ChittyInstitute of Child Health, Great Ormond Street Hospital for Children NHS Trust, Clinical and Molecular Genetics, 30 Guildford Street, London WC1N 6EH, UK+0207 905 2876; +0207 380 9984; [email protected]
Pages S119-S126 | Published online: 16 Apr 2012

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Jean Gekas, Sylvie Langlois, Vardit Ravitsky, François Audibert, David Gradus van den Berg, Hazar Haidar & François Rousseau. (2016) Non-invasive prenatal testing for fetal chromosome abnormalities: review of clinical and ethical issues. The Application of Clinical Genetics 9, pages 15-26.
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Articles from other publishers (36)

Soojin Kim, Esther L. Finney, Ushasi Naha, Ilina Rosoklija, Kyle S. Honegger, Allison Goetsch Weisman, Jane L. Holl, Courtney Finlayson, Diane Chen & Emilie K. Johnson. (2023) Comparison of web-based information about cell-free DNA prenatal screening: implications for differences of sex development care. Frontiers in Urology 3.
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Mathilde Pacault, Camille Verebi, Magali Champion, Lucie Orhant, Alexandre Perrier, Emmanuelle Girodon, France Leturcq, Dominique Vidaud, Claude Férec, Thierry Bienvenu, Romain Daveau & Juliette Nectoux. (2023) Non-invasive prenatal diagnosis of single gene disorders with enhanced relative haplotype dosage analysis for diagnostic implementation. PLOS ONE 18:4, pages e0280976.
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Maria I. New & Dennis Lo. 2023. Genetic Steroid Disorders. Genetic Steroid Disorders 111 121 .
Britt Hanson, Elizabeth Scotchman, Lyn S. Chitty & Natalie J. Chandler. (2022) Non-invasive prenatal diagnosis (NIPD): how analysis of cell-free DNA in maternal plasma has changed prenatal diagnosis for monogenic disorders. Clinical Science 136:22, pages 1615-1629.
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Žana Stanić, Zlatko Hrgović, Rajko Fureš, Iva Vusić & Marko Lagančić. (2022) Ethical Aspects of Prenatal DNA Testing. Zeitschrift für Geburtshilfe und Neonatologie 226:05, pages 300-303.
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Aubrey Milunsky & Jeff M. MilunskyIgnatia B. Van den Veyver, Natalie Chandler & Lyn S. Chitty. 2021. Genetic Disorders and the Fetus. Genetic Disorders and the Fetus 318 345 .
Mohammad Hossein Ahmadi, Naser Amirizadeh, Maryam Rabiee, Fatemeh Rahimi-Sharbaf & Ali Akbar Pourfathollah. (2020) Noninvasive Fetal Sex Determination by Real-Time PCR and TaqMan Probes. Reports of Biochemistry and Molecular Biology 9:3, pages 315-323.
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Maria‐Elisabeth Smet, Fergus P. Scott & Andrew C. McLennan. (2020) Discordant fetal sex on NIPT and ultrasound. Prenatal Diagnosis 40:11, pages 1353-1365.
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Elizabeth Young, Benjamin Bowns, Amy Gerrish, Michael Parks, Samantha Court, Samuel Clokie, Chipo Mashayamombe-Wolfgarten, Julie Hewitt, Denise Williams, Trevor Cole & Stephanie Allen. (2020) Clinical Service Delivery of Noninvasive Prenatal Diagnosis by Relative Haplotype Dosage for Single-Gene Disorders. The Journal of Molecular Diagnostics 22:9, pages 1151-1161.
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Natalie J Chandler, Helena Ahlfors, Suzanne Drury, Rhiannon Mellis, Melissa Hill, Fiona J McKay, Claire Collinson, Jane Hayward, Lucy Jenkins & Lyn S Chitty. (2020) Noninvasive Prenatal Diagnosis for Cystic Fibrosis: Implementation, Uptake, Outcome, and Implications. Clinical Chemistry 66:1, pages 207-216.
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Rezan KadirRezan A. Kadir, Irena Hudecova & Claudia Chi. 2019. Inherited Bleeding Disorders in Women 2e. Inherited Bleeding Disorders in Women 2e 167 189 .
Peter Miny, Isabel Filges, Sevgi Tercanli & Wolfgang Holzgreve. 2005. Encyclopedia of Life Sciences. Encyclopedia of Life Sciences 1 7 .
Lin–Lin LIU, Meng–Lin ZHENG, Bing–Jie ZOU, Qin–Xin SONG & Guo–Hua ZHOU. (2017) Highly Sensitive and Specific Detection of SRY Gene for Non–invasive Prenatal Diagnosis. Chinese Journal of Analytical Chemistry 45:10, pages 1448-1454.
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Michael Parks, Samantha Court, Benjamin Bowns, Siobhan Cleary, Samuel Clokie, Julie Hewitt, Denise Williams, Trevor Cole, Fiona MacDonald, Mike Griffiths & Stephanie Allen. (2017) Non-invasive prenatal diagnosis of spinal muscular atrophy by relative haplotype dosage. European Journal of Human Genetics 25:4, pages 416-422.
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Irena Hudecova & Rossa W.K. Chiu. (2017) Non-invasive prenatal diagnosis of thalassemias using maternal plasma cell free DNA. Best Practice & Research Clinical Obstetrics & Gynaecology 39, pages 63-73.
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F. R. Grati. (2016) Implications of fetoplacental mosaicism on cell-free DNA testing: a review of a common biological phenomenon. Ultrasound in Obstetrics & Gynecology 48:4, pages 415-423.
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Dana Tsui & Muhammed Murtaza. 2016. Cancer Genetics and Genomics for Personalized Medicine. Cancer Genetics and Genomics for Personalized Medicine 53 75 .
Michael Parks, Samantha Court, Siobhan Cleary, Samuel Clokie, Julie Hewitt, Denise Williams, Trevor Cole, Fiona MacDonald, Mike Griffiths & Stephanie Allen. (2016) Non-invasive prenatal diagnosis of Duchenne and Becker muscular dystrophies by relative haplotype dosage. Prenatal Diagnosis 36:4, pages 312-320.
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Laura Pisnoli, Anita O’Connor, Lesley Goldsmith, Leigh Jackson & Heather Skirton. (2016) Impact of fetal or child loss on parents’ perceptions of non-invasive prenatal diagnosis for autosomal recessive conditions. Midwifery 34, pages 105-110.
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Suzanne Drury, Sarah Mason, Fiona McKay, Kitty Lo, Christopher Boustred, Lucy Jenkins & Lyn S. Chitty. 2016. Circulating Nucleic Acids in Serum and Plasma ? CNAPS IX. Circulating Nucleic Acids in Serum and Plasma ? CNAPS IX 71 75 .
Heather Skirton. (2015) Direct to consumer testing in reproductive contexts – should health professionals be concerned?. Life Sciences, Society and Policy 11:1.
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Melissa Hill & Lyn S. Chitty. 2015. Genetic Disorders and the Fetus. Genetic Disorders and the Fetus 453 482 .
Caroline Silcock, Lih-Mei Liao, Melissa Hill & Lyn S. Chitty. (2015) Will the introduction of non-invasive prenatal testing for Down's syndrome undermine informed choice?. Health Expectations 18:5, pages 1658-1671.
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D. S. C. Han & Y. M. D. Lo. (2015) Non-invasive prenatal testing of monogenic fetal characteristics by maternal plasma DNA analysis. ISBT Science Series 10:S1, pages 197-205.
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Diana W. Bianchi, Saba Parsa, Sucheta Bhatt, Meredith Halks-Miller, Kathryn Kurtzman, Amy J. Sehnert & Amy Swanson. (2015) Fetal Sex Chromosome Testing by Maternal Plasma DNA Sequencing. Obstetrics & Gynecology 125:2, pages 375-382.
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S. Traver, S. Assou, E. Scalici, D. Haouzi, T. Al-Edani, S. Belloc & S. Hamamah. (2014) Cell-free nucleic acids as non-invasive biomarkers of gynecological cancers, ovarian, endometrial and obstetric disorders and fetal aneuploidy. Human Reproduction Update 20:6, pages 905-923.
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Mahsa Motavaf & Majid Sadeghizadeh. (2014) Noninvasive Prenatal Test by Cell-Free Fetal DNA in Maternal Plasma: Current Progress and Prospective Clinical Applications. Journal of Comprehensive Pediatrics 5:3.
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Lyn S. Chitty. (2014) Cell-free DNA testing: An aid to prenatal sonographic diagnosis. Best Practice & Research Clinical Obstetrics & Gynaecology 28:3, pages 453-466.
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Gary J.W. Liao, Ann M. Gronowski & Zhen Zhao. (2014) Non-invasive prenatal testing using cell-free fetal DNA in maternal circulation. Clinica Chimica Acta 428, pages 44-50.
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Denesy Mancenido & Maria I. New. 2014. Genetic Steroid Disorders. Genetic Steroid Disorders 53 62 .
Lyn S. Chitty & Diana W. Bianchi. (2013) Noninvasive prenatal testing: the paradigm is shifting rapidly. Prenatal Diagnosis 33:6, pages 511-513.
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Nicholas Lench, Angela Barrett, Sarah Fielding, Fiona McKay, Melissa Hill, Lucy Jenkins, Helen White & Lyn S. Chitty. (2013) The clinical implementation of non-invasive prenatal diagnosis for single-gene disorders: challenges and progress made. Prenatal Diagnosis 33:6, pages 555-562.
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. (2013) Current World Literature. Current Opinion in Obstetrics & Gynecology 25:2, pages 157-166.
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Rossa Wai Kwun Chiu & Yuk Ming Dennis Lo. (2013) Clinical applications of maternal plasma fetal DNA analysis: translating the fruits of 15 years of research. Clinical Chemistry and Laboratory Medicine (CCLM) 51:1, pages 197-204.
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Lyn S. Chitty, Pierre Chatelain, Katja P. Wolffenbuttel & Yves Aigrain. (2012) Prenatal management of disorders of Sex development. Journal of Pediatric Urology 8:6, pages 576-584.
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Melissa Hill, Angela N. Barrett, Helen White & Lyn S. Chitty. (2012) Uses of cell free fetal DNA in maternal circulation. Best Practice & Research Clinical Obstetrics & Gynaecology 26:5, pages 639-654.
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