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Expert Opinion on Biological Therapy Volume 12, 2012 - Issue 4
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Drug Evaluations

The role of cetuximab in the management of head and neck cancers

Peyman KabolizadehUniversity of Pittsburgh Cancer Institute, Department of Radiation Oncology, Pittsburgh, PA, USA
, MD PhD,
Gregory J KubicekUniversity of Pittsburgh Cancer Institute, Department of Radiation Oncology, Pittsburgh, PA, USA
, MD,
Dwight E HeronUniversity of Pittsburgh Cancer Institute, Department of Radiation Oncology, Pittsburgh, PA, USA;University of Pittsburgh Cancer Institute, Department of Otolaryngology, Head & Neck Surgery, Pittsburgh, PA, USA
, MD FACRO,
Robert L FerrisUniversity of Pittsburgh Cancer Institute, Department of Radiation Oncology, Pittsburgh, PA, USA;University of Pittsburgh Cancer Institute, Department of Otolaryngology, Head & Neck Surgery, Pittsburgh, PA, USA
, MD PhD &
Michael K GibsonUniversity of Pittsburgh Cancer Institute, Division of Hematology/Oncology, Department of Medicine, UPMC Cancer Pavilion 5150 Center Avenue, Fifth Floor, Pittsburgh, PA 15232, USA+1 412 623 2393; +1 412 648 6579; [email protected]
, MD PhD FACP
Pages 517-528 | Published online: 13 Mar 2012

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Gamze Ugurluer & Mahmut Ozsahin. (2014) Early investigational drugs that target epidermal growth factor receptors for the treatment of head and neck cancer. Expert Opinion on Investigational Drugs 23:12, pages 1637-1654.
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Niamh McDermott, Armelle Meunier, Thomas H. Lynch, Donal Hollywood & Laure Marignol. (2014) Isogenic radiation resistant cell lines: Development and validation strategies. International Journal of Radiation Biology 90:2, pages 115-126.
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Takumi Sato, Yasumasa Kakei, Takumi Hasegawa, Masahiko Kashin, Shun Teraoka, Akinobu Yamaguchi, Ryohei Sasaki & Masaya Akashi. (2023) Gold Nanoparticles Enhance the Tumor Growth-Suppressing Effects of Cetuximab and Radiotherapy in Head and Neck Cancer In Vitro and In Vivo. Cancers 15:23, pages 5697.
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Jason Tasoulas, Sonal Srivastava, Xiaonan Xu, Valentina Tarasova, Anastasios Maniakas, Florian A. Karreth & Antonio L. Amelio. (2023) Genetically engineered mouse models of head and neck cancers. Oncogene.
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Aisha Al Anaz, Ravi Teja Chitturi Suryaprakash, Kate Shearston & Omar Kujan. 2023. Molecular Targets and Cancer Therapeutics (Part 1). Molecular Targets and Cancer Therapeutics (Part 1) 187 241 .
Qingfang Li, Yan Tie, Aqu Alu, Xuelei Ma & Huashan Shi. (2023) Targeted therapy for head and neck cancer: signaling pathways and clinical studies. Signal Transduction and Targeted Therapy 8:1.
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Silvia Pisani, Giulia Bertino, Adriele Prina-Mello, Laura Deborah Locati, Simone Mauramati, Ida Genta, Rossella Dorati, Bice Conti & Marco Benazzo. (2022) Electroporation in Head-and-Neck Cancer: An Innovative Approach with Immunotherapy and Nanotechnology Combination. Cancers 14:21, pages 5363.
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Lejla Mahmutović, Esma Bilajac & Altijana Hromić-Jahjefendić. (2021) Meet the Insidious Players: Review of Viral Infections in Head and Neck Cancer Etiology with an Update on Clinical Trials. Microorganisms 9:5, pages 1001.
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Leonardo Muratori, Anna La Salvia, Gabriella Gorzegno, Paola Sperone & Giorgio V Scagliotti. (2019) Long-term disease control in a metastatic squamous cell carcinoma of the oral cavity treated with maintenance metronomic capecitabine. Journal of Oncology Pharmacy Practice 26:1, pages 240-243.
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Bao T. Le, Prithi Raguraman, Tamer R. Kosbar, Susan Fletcher, Steve D. Wilton & Rakesh N. Veedu. (2019) Antisense Oligonucleotides Targeting Angiogenic Factors as Potential Cancer Therapeutics. Molecular Therapy - Nucleic Acids 14, pages 142-157.
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Zhichu Xiang, Xiaoliang Yang, Junjie Xu, Wenjia Lai, Zihua Wang, Zhiyuan Hu, Jiesheng Tian, Lingling Geng & Qiaojun Fang. (2017) Tumor detection using magnetosome nanoparticles functionalized with a newly screened EGFR/HER2 targeting peptide. Biomaterials 115, pages 53-64.
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R. Ajina, D. AlDeghaither, S. Jablonski & L.M. Weiner. 2017. Comprehensive Medicinal Chemistry III. Comprehensive Medicinal Chemistry III 32 65 .
Omer Tarık Selcuk. (2016) Human papillomavirus positive oropharyngeal cancer: The general information. Egyptian Journal of Ear, Nose, Throat and Allied Sciences 17:3, pages 127-132.
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Jacopo Giuliani & Andrea Bonetti. (2015) Cisplatin versus cetuximab given concomitantly with radiotherapy in non-resectable head and neck squamous cell carcinoma:an open question. European Archives of Oto-Rhino-Laryngology 273:1, pages 263-265.
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Jonathan Rios-Doria, Darrin Sabol, Jon Chesebrough, Dave Stewart, Linda Xu, Ravinder Tammali, Li Cheng, Qun Du, Kevin Schifferli, Ray Rothstein, Ching Ching Leow, Jenny Heidbrink-Thompson, Xiaofang Jin, Changshou Gao, Jay Friedman, Brandy Wilkinson, Melissa Damschroder, Andrew J. Pierce, Robert E. Hollingsworth, David A. Tice & Emil F. Michelotti. (2015) A Monoclonal Antibody to ADAM17 Inhibits Tumor Growth by Inhibiting EGFR and Non–EGFR-Mediated Pathways. Molecular Cancer Therapeutics 14:7, pages 1637-1649.
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Neil Gildener-Leapman, John Lee & Robert L. Ferris. (2014) Tailored immunotherapy for HPV positive head and neck squamous cell cancer. Oral Oncology 50:9, pages 780-784.
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Hui-Xia Feng, Su-Ping Guo, Gui-Rong Li, Wen-Huan Zhong, Liu Chen, Li-Ru Huang & Hui-Ying Qin. (2014) Toxicity of concurrent chemoradiotherapy with cetuximab for locoregionally advanced nasopharyngeal carcinoma. Medical Oncology 31:9.
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Jacopo Giuliani & Marina Marzola. (2014) Cetuximab/cisplatin and radiotherapy in HNSCC: is there a favorite choice?. Open Medicine 9:2, pages 279-284.
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Orit Jacobson & Xiaoyuan Chen. (2013) Interrogating Tumor Metabolism and Tumor Microenvironments Using Molecular Positron Emission Tomography Imaging. Theranostic Approaches to Improve Therapeutics. Pharmacological Reviews 65:4, pages 1214-1256.
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Meng Tong, Byungdo B. Han, Andrew S. Holpuch, Ping Pei, Lingli He & Susan R. Mallery. (2013) Inherent phenotypic plasticity facilitates progression of head and neck cancer: Endotheliod characteristics enable angiogenesis and invasion. Experimental Cell Research 319:7, pages 1028-1042.
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Marij J.P. Welters & Sjoerd H. van der Burg. 2013. Cancer Immunotherapy. Cancer Immunotherapy 241 258 .
Devalingam Mahalingam & Tyler J. Curiel. 2013. Cancer Immunotherapy. Cancer Immunotherapy 335 376 .

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