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Drug Evaluations

Inhibition of placenta growth factor with TB-403: a novel antiangiogenic cancer therapy

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Pages 795-804 | Published online: 16 Apr 2012

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David Van Mater & Lars Wagner. (2019) Management of recurrent Ewing sarcoma: challenges and approaches. OncoTargets and Therapy 12, pages 2279-2288.
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Mieke Dewerchin & Peter Carmeliet. (2014) Placental growth factor in cancer. Expert Opinion on Therapeutic Targets 18:11, pages 1339-1354.
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Giselle Saulnier-Sholler, Dan G. Duda, Genevieve Bergendahl, David Ebb, Matija Snuderl, Theodore W. Laetsch, Jennifer Michlitsch, Derek Hanson, Michael S. Isakoff, Kevin Bielamowicz, Jacqueline M. Kraveka, William Ferguson, Peter Carmeliet, A. De Deene, Lore Gijsen & Rakesh K. Jain. (2022) A Phase I Trial of TB-403 in Relapsed Medulloblastoma, Neuroblastoma, Ewing Sarcoma, and Alveolar Rhabdomyosarcoma. Clinical Cancer Research 28:18, pages 3950-3957.
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Claudia Ceci, Maria Grazia Atzori, Pedro Miguel Lacal & Grazia Graziani. (2020) Role of VEGFs/VEGFR-1 Signaling and Its Inhibition in Modulating Tumor Invasion: Experimental Evidence in Different Metastatic Cancer Models. International Journal of Molecular Sciences 21:4, pages 1388.
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Loredana Albonici, Maria Gabriella Giganti, Andrea Modesti, Vittorio Manzari & Roberto Bei. (2019) Multifaceted Role of the Placental Growth Factor (PlGF) in the Antitumor Immune Response and Cancer Progression. International Journal of Molecular Sciences 20:12, pages 2970.
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Ahmed M. Al-Abd, Abdulmohsin J. Alamoudi, Ashraf B. Abdel-Naim, Thikryat A. Neamatallah & Osama M. Ashour. (2017) Anti-angiogenic agents for the treatment of solid tumors: Potential pathways, therapy and current strategies – A review. Journal of Advanced Research 8:6, pages 591-605.
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Lindsey Devisscher, Margherita Vieri, Susan E. Logue, Jens Panse, Anja Geerts, Hans van Vlierberghe, Eric Chevet, Adrienne M. Gorman, Afshin Samali & Behzad Kharabi Masouleh. (2016) Targeting the angio-proteostasis network: Combining the forces against cancer. Pharmacology & Therapeutics 167, pages 1-12.
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Hyun Jung Koo, Myoungsun Lee, Jin Kim, Chul Woong Woo, Seong-Yun Jeong, Eun Kyung Choi, Namkug Kim & Jin Seong Lee. (2016) Synergistic Effect of Anti-Angiogenic and Radiation Therapy: Quantitative Evaluation with Dynamic Contrast Enhanced MR Imaging. PLOS ONE 11:2, pages e0148784.
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Luis Mario Aguirre Palma, Iris Gehrke & Karl-Anton Kreuzer. (2015) Angiogenic factors in chronic lymphocytic leukaemia (CLL): Where do we stand?. Critical Reviews in Oncology/Hematology 93:3, pages 225-236.
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Thijs H. Oude Munnink, Karin R. Tamas, Marjolijn N. Lub-de Hooge, Silke R. Vedelaar, Hetty Timmer-Bosscha, Annemiek M.E. Walenkamp, K. Michael Weidner, Frank Herting, Jean Tessier & Elisabeth G.E. de Vries. (2013) Placental Growth Factor (PlGF)–Specific Uptake in Tumor Microenvironment of 89 Zr-Labeled PlGF Antibody RO5323441 . Journal of Nuclear Medicine 54:6, pages 929-935.
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Matija Snuderl, Ana Batista, Nathaniel D. Kirkpatrick, Carmen Ruiz de Almodovar, Lars Riedemann, Elisa C. Walsh, Rachel Anolik, Yuhui Huang, John D. Martin, Walid Kamoun, Ellen Knevels, Thomas Schmidt, Christian T. Farrar, Benjamin J. Vakoc, Nishant Mohan, Euiheon Chung, Sylvie Roberge, Teresa Peterson, Carlos Bais, Boryana H. Zhelyazkova, Stephen Yip, Martin Hasselblatt, Claudia Rossig, Elisabeth Niemeyer, Napoleone Ferrara, Michael Klagsbrun, Dan G. Duda, Dai Fukumura, Lei Xu, Peter Carmeliet & Rakesh K. Jain. (2013) Targeting Placental Growth Factor/Neuropilin 1 Pathway Inhibits Growth and Spread of Medulloblastoma. Cell 152:5, pages 1065-1076.
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