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Non-neutralizing antibodies in prevention of HIV infection

Pages 197-207 | Published online: 06 Nov 2012

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Lynette Siv Chea & Rama Rao Amara. (2017) Immunogenicity and efficacy of DNA/MVA HIV vaccines in rhesus macaque models. Expert Review of Vaccines 16:10, pages 973-985.
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Diana Stoycheva, Ioana Sandu, Fabienne Gräbnitz, Ana Amorim, Mariana Borsa, Stefan Weber, Burkhard Becher & Annette Oxenius. (2021) Non‐neutralizing antibodies protect against chronic LCMV infection by promoting infection of inflammatory monocytes in mice. European Journal of Immunology 51:6, pages 1423-1435.
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Sudhir Pai Kasturi, Mohammed Ata Ur Rasheed, Colin Havenar-Daughton, Mathew Pham, Traci Legere, Zarpheen Jinnah SherYevgeny Kovalenkov, Sanjeev Gumber, Jessica Y. Huang, Raphael Gottardo, William FulpAlicia Sato, Sheetal Sawant, Sherry Stanfield-Oakley, Nicole Yates, Celia LaBranche, S. Munir Alam, Georgia TomarasGuido FerrariDavid Montefiori, Jens Wrammert, Francois Villinger, Mark Tomai, John VasilakosChristopher B. Fox, Steven G. ReedBarton F. HaynesShane Crotty, Rafi Ahmed & Bali Pulendran. (2020) 3M-052, a synthetic TLR-7/8 agonist, induces durable HIV-1 envelope–specific plasma cells and humoral immunity in nonhuman primates. Science Immunology 5:48.
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Sabrina Helmold Hait, Christopher James Hogge, Mohammad Arif Rahman, Eun-Ju Ko, Ruth Hunegnaw, Zuena Mushtaq, Gospel Enyindah-Asonye, Tanya Hoang, Lisa M. Miller Jenkins, Ettore Appella, Daniel H. Appella & Marjorie Robert-Guroff. (2020) An SAMT-247 Microbicide Provides Potent Protection against Intravaginal Simian Immunodeficiency Virus Infection of Rhesus Macaques, whereas an Added Vaccine Component Elicits Mixed Outcomes. The Journal of Immunology 204:12, pages 3315-3328.
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Andrew T. Jones, Xiaoying Shen, Korey L. Walter, Celia C. LaBranche, Linda S. Wyatt, Georgia D. Tomaras, David C. Montefiori, Bernard Moss, Dan H. Barouch, John D. Clements, Pamela A. Kozlowski, Raghavan Varadarajan & Rama Rao Amara. (2019) HIV-1 vaccination by needle-free oral injection induces strong mucosal immunity and protects against SHIV challenge. Nature Communications 10:1.
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Massimiliano Bissa, Greta Forlani, Carlo Zanotto, Giovanna Tosi, Carlo De Giuli Morghen, Roberto S. Accolla & Antonia Radaelli. (2018) Fowlpoxvirus recombinants coding for the CIITA gene increase the expression of endogenous MHC-II and Fowlpox Gag/Pro and Env SIV transgenes. PLOS ONE 13:1, pages e0190869.
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Keshet Ronen, Caitlin Milligan & Julie Overbaugh. 2018. Encyclopedia of AIDS. Encyclopedia of AIDS 1810 1818 .
A. N. Vzorov & L. V. Uryvaev. (2017) Requirements for the Induction of Broadly Neutralizing Antibodies against HIV-1 by Vaccination. Molecular Biology 51:6, pages 819-829.
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Ivana K. Parker, Krystin Ambrose Price, Tyana Singletary, Priya Srinivasan, James M. Smith & Kelly A. Curtis. (2017) A multiplex assay for detection of SHIV plasma and mucosal IgG and IgA. Journal of Immunological Methods 450, pages 34-40.
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Susan P. Buchbinder, Nicole A. Grunenberg, Brittany J. Sanchez, Kelly E. Seaton, Guido Ferrari, M. Anthony Moody, Nicole Frahm, David C. Montefiori, Christine M. Hay, Paul A. Goepfert, Lindsey R. Baden, Harriet L. Robinson, Xuesong Yu, Peter B. Gilbert, M. Juliana McElrath, Yunda Huang & Georgia D. Tomaras. (2017) Immunogenicity of a novel Clade B HIV-1 vaccine combination: Results of phase 1 randomized placebo controlled trial of an HIV-1 GM-CSF-expressing DNA prime with a modified vaccinia Ankara vaccine boost in healthy HIV-1 uninfected adults. PLOS ONE 12:7, pages e0179597.
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Kenneth C. BagleyJennifer A. SchwartzHanne AndersenJohn H. EldridgeRong XuAyuko Ota-SetlikJoshua J. GeltzWilliam P. HalfordTimothy R. Fouts. (2017) An Interleukin 12 Adjuvanted Herpes Simplex Virus 2 DNA Vaccine Is More Protective Than a Glycoprotein D Subunit Vaccine in a High-Dose Murine Challenge Model. Viral Immunology 30:3, pages 178-195.
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Sudhir Pai Kasturi, Pamela A. Kozlowski, Helder I. Nakaya, Matheus C. Burger, Pedro Russo, Mathew Pham, Yevgeniy Kovalenkov, Eduardo L. V. Silveira, Colin Havenar-Daughton, Samantha L. Burton, Katie M. Kilgore, Mathew J. Johnson, Rafiq Nabi, Traci Legere, Zarpheen Jinnah Sher, Xuemin Chen, Rama R. Amara, Eric Hunter, Steven E. Bosinger, Paul Spearman, Shane Crotty, Francois Villinger, Cynthia A. Derdeyn, Jens Wrammert & Bali Pulendran. (2017) Adjuvanting a Simian Immunodeficiency Virus Vaccine with Toll-Like Receptor Ligands Encapsulated in Nanoparticles Induces Persistent Antibody Responses and Enhanced Protection in TRIM5α Restrictive Macaques. Journal of Virology 91:4.
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Susan Zolla-Pazner, Rebecca Powell, Sara Yahyaei, Constance Williams, Xunqing Jiang, Wei Li, Shan Lu, Shixia Wang, Chitra Upadhyay, Catarina E. Hioe, Max Totrov & Xiangpeng Kong. (2016) Rationally Designed Vaccines Targeting the V2 Region of HIV-1 gp120 Induce a Focused, Cross-Clade-Reactive, Biologically Functional Antibody Response. Journal of Virology 90:24, pages 10993-11006.
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Emmanuel Ato Williams, David J.M. Lewis, Sylvie Bertholet & Maurizio Zazzi. (2016) Anticipating policy considerations for a future HIV vaccine: a preliminary study. Vaccine 34:32, pages 3697-3701.
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Rosemarie D. Mason, Hugh C. Welles, Cameron Adams, Bimal K. Chakrabarti, Jason Gorman, Tongqing Zhou, Richard Nguyen, Sijy O’Dell, Sabrina Lusvarghi, Carole A. Bewley, Hui Li, George M. Shaw, Zizhang Sheng, Lawrence Shapiro, Richard Wyatt, Peter D. Kwong, John R. Mascola & Mario Roederer. (2016) Targeted Isolation of Antibodies Directed against Major Sites of SIV Env Vulnerability. PLOS Pathogens 12:4, pages e1005537.
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Megan C. Wise, Natalie A. Hutnick, Justin Pollara, Devin J. F. Myles, Constance Williams, Jian Yan, Celia C. LaBranche, Amir S. Khan, Niranjan Y. Sardesai, David Montefiori, Susan W. Barnett, Susan Zolla-Pazner, Guido Ferrari & David B. Weiner. (2015) An Enhanced Synthetic Multiclade DNA Prime Induces Improved Cross-Clade-Reactive Functional Antibodies when Combined with an Adjuvanted Protein Boost in Nonhuman Primates. Journal of Virology 89:18, pages 9154-9166.
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Wilton B. WilliamsHua-Xin LiaoM. Anthony MoodyThomas B. KeplerS. Munir AlamFeng GaoKevin WieheAshley M. TramaKathryn JonesRuijun ZhangHongshuo SongDawn J. MarshallJohn F. WhitesidesKaitlin SawatzkiAxin HuaPinghuang LiuMatthew Z. TayKelly E. SeatonXiaoying ShenAndrew FoulgerKrissey E. LloydRobert ParksJustin PollaraGuido FerrariJae-Sung YuNathan VandergriftDavid C. MontefioriMagdalena E. SobieszczykScott HammerShelly KarunaPeter GilbertDoug GroveNicole GrunenbergM. Juliana McElrathJohn R. MascolaRichard A. KoupLawrence CoreyGary J. NabelCecilia MorganGavin ChurchyardJanine MaenzaMichael KeeferBarney S. GrahamLindsey R. BadenGeorgia D. TomarasBarton F. Haynes. (2015) Diversion of HIV-1 vaccine–induced immunity by gp41-microbiota cross-reactive antibodies. Science 349:6249.
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Agricola Joachim, Charlotta Nilsson, Said Aboud, Muhammad Bakari, Eligius F. Lyamuya, Merlin L. Robb, Mary A. Marovich, Patricia Earl, Bernard Moss, Christina Ochsenbauer, Britta Wahren, Fred Mhalu, Eric Sandstr?m, Gunnel Biberfeld, Guido Ferrari & Victoria R. Polonis. (2015) Potent Functional Antibody Responses Elicited by HIV-I DNA Priming and Boosting with Heterologous HIV-1 Recombinant MVA in Healthy Tanzanian Adults. PLOS ONE 10:4, pages e0118486.
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Massimiliano Bissa, Carlo Zanotto, Sole Pacchioni, Luca Volonté, Aldo Venuti, David Lembo, Carlo De Giuli Morghen & Antonia Radaelli. (2015) The L1 protein of human papilloma virus 16 expressed by a fowlpox virus recombinant can assemble into virus-like particles in mammalian cell lines but elicits a non-neutralising humoral response. Antiviral Research 116, pages 67-75.
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Huanbin Xu, Xiaolei Wang & Ronald S. Veazey. 2015. Mucosal Immunology. Mucosal Immunology 1493 1520 .
Michael A. Thomas, Iskra Tuero, Thorsten Demberg, Diego A. Vargas-Inchaustegui, Thomas Musich, Peng Xiao, David Venzon, Celia LaBranche, David C. Montefiori, Janet DiPasquale, Steven G. Reed, Anthony DeVico, Timothy Fouts, George K. Lewis, Robert C. Gallo & Marjorie Robert-Guroff. (2014) HIV-1 CD4-induced (CD4i) gp120 epitope vaccines promote B and T-cell responses that contribute to reduced viral loads in rhesus macaques. Virology 471-473, pages 81-92.
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Jacquelyn L Schwartz. (2014) Fcgbp – A Potential Viral Trap in RV144. The Open AIDS Journal 8:1, pages 21-24.
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Jean-Louis Excler, Julie Ake, Merlin L. Robb, Jerome H. Kim & Stanley A. Plotkin. (2014) Nonneutralizing Functional Antibodies: a New “Old” Paradigm for HIV Vaccines. Clinical and Vaccine Immunology 21:8, pages 1023-1036.
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Diego A. Vargas-Inchaustegui, Iskra Tuero, Venkatramanan Mohanram, Thomas Musich, Poonam Pegu, Antonio Valentin, Yongjun Sui, Margherita Rosati, Jenifer Bear, David J. Venzon, Viraj Kulkarni, Candido Alicea, Guy R. Pilkington, Namal P.M. Liyanage, Thorsten Demberg, Shari N. Gordon, Yichuan Wang, Alison E. Hogg, Blake Frey, L. Jean Patterson, Janet DiPasquale, David C. Montefiori, Niranjan Y. Sardesai, Steven G. Reed, Jay A. Berzofsky, Genoveffa Franchini, Barbara K. Felber, George N. Pavlakis & Marjorie Robert-Guroff. (2014) Humoral immunity induced by mucosal and/or systemic SIV-specific vaccine platforms suggests novel combinatorial approaches for enhancing responses. Clinical Immunology 153:2, pages 308-322.
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Paul A. Goepfert, Marnie L. Elizaga, Kelly Seaton, Georgia D. Tomaras, David C. Montefiori, Alicia Sato, John Hural, Stephen C. DeRosa, Spyros A. Kalams, M. Juliana McElrath, Michael C. Keefer, Lindsey R. Baden, Javier R. Lama, Jorge Sanchez, Mark J. Mulligan, Susan P. Buchbinder, Scott M. Hammer, Beryl A. Koblin, Michael Pensiero, Chris Butler, Bernard Moss & Harriet L. Robinson. (2014) Specificity and 6-Month Durability of Immune Responses Induced by DNA and Recombinant Modified Vaccinia Ankara Vaccines Expressing HIV-1 Virus-Like Particles. The Journal of Infectious Diseases 210:1, pages 99-110.
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Raymond A. Alvarez, Rebecca E. Hamlin, Anthony Monroe, Brian Moldt, Mathew T. Hotta, Gabriela Rodriguez Caprio, Daniel S. Fierer, Viviana Simon & Benjamin K. Chen. (2014) HIV-1 Vpu Antagonism of Tetherin Inhibits Antibody-Dependent Cellular Cytotoxic Responses by Natural Killer Cells. Journal of Virology 88:11, pages 6031-6046.
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Stanley A. Plotkin. (2014) Problems in Vaccine Development. Monoclonal Antibodies in Immunodiagnosis and Immunotherapy 33:3, pages 166-167.
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George K. Lewis, Yongjun Guan, Roberta Kamin-Lewis, Mohammad Sajadi, Marzena Pazgier & Anthony L. Devico. (2014) Epitope target structures of Fc-mediated effector function during HIV-1 acquisition. Current Opinion in HIV and AIDS 9:3, pages 263-270.
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Sandeep Raja Dangeti. (2014) Distinct advancements and challenges in HIV 1 vaccine development and cure—A review. HIV & AIDS Review 13:1, pages 1-5.
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Keshet Ronen, Caitlin Milligan & Julie Overbaugh. 2021. Encyclopedia of AIDS. Encyclopedia of AIDS 1 9 .
Olga Pleguezuelos, Gregory A Stoloff & Wilson Caparrós-Wanderley. (2013) Synthetic immunotherapy induces HIV virus specific Th1 cytotoxic response and death of an HIV-1 infected human cell line through classic complement activation. Virology Journal 10:1.
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Yehuda Z. Cohen & Raphael Dolin. (2013) Novel HIV vaccine strategies: overview and perspective. Therapeutic Advances in Vaccines 1:3, pages 99-112.
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José Esparza. (2013) A brief history of the global effort to develop a preventive HIV vaccine. Vaccine 31:35, pages 3502-3518.
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Kathryn E. Stephenson & Dan H. Barouch. (2013) A global approach to HIV ‐1 vaccine development . Immunological Reviews 254:1, pages 295-304.
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Krystal Teasley Hamorsky, Tiffany W. Grooms-Williams, Adam S. Husk, Lauren J. Bennett, Kenneth E. Palmer & Nobuyuki Matoba. (2013) Efficient Single Tobamoviral Vector-Based Bioproduction of Broadly Neutralizing Anti-HIV-1 Monoclonal Antibody VRC01 in Nicotiana benthamiana Plants and Utility of VRC01 in Combination Microbicides. Antimicrobial Agents and Chemotherapy 57:5, pages 2076-2086.
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