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New era of biologic therapeutics in atopic dermatitis

, MD PhD, , BS & , MD PhD
Pages 549-561 | Published online: 16 Jan 2013

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Daniela Mikhaylov, Ester Del Duca & Emma Guttman-Yassky. (2021) Proteomic signatures of inflammatory skin diseases: a focus on atopic dermatitis. Expert Review of Proteomics 18:5, pages 345-361.
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Noha S. El-Salamouni, Mai M. Ali, Sherien A. Abdelhady, Lamia S. Kandil, Gihan A. Elbatouti & Ragwa M. Farid. (2020) Evaluation of chamomile oil and nanoemulgels as a promising treatment option for atopic dermatitis induced in rats. Expert Opinion on Drug Delivery 17:1, pages 111-122.
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Nilika Bhattacharya, Gitali Ganguli-Indra & Arup K. Indra. (2019) Transcriptional control and transcriptomic analysis of lipid metabolism in skin barrier formation and atopic dermatitis (AD). Expert Review of Proteomics 16:8, pages 627-645.
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Randall Li, Suhail Hadi & Emma Guttman-Yassky. (2019) Current and emerging biologic and small molecule therapies for atopic dermatitis. Expert Opinion on Biological Therapy 19:4, pages 367-380.
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Yunlei Pan, Lina Xu, Jianjun Qiao & Hong Fang. (2018) A systematic review of ustekinumab in the treatment of atopic dermatitis. Journal of Dermatological Treatment 29:6, pages 539-541.
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Kam Lun Hon, Alexander K.C. Leung, Theresa N. H. Leung & Vivian W. Y. Lee. (2018) Investigational drugs for atopic dermatitis. Expert Opinion on Investigational Drugs 27:8, pages 637-647.
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Dylan E. Lee, Ashley K. Clark, Khiem A. Tran & Vivian Y. Shi. (2018) New and emerging targeted systemic therapies: a new era for atopic dermatitis. Journal of Dermatological Treatment 29:4, pages 364-374.
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Laurie A. Manka & Michael E. Wechsler. (2018) New biologics for allergic diseases. Expert Review of Clinical Immunology 14:4, pages 285-296.
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Marianne B Løvendorf & Lone Skov. (2015) miRNAs in inflammatory skin diseases and their clinical implications. Expert Review of Clinical Immunology 11:4, pages 467-477.
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Hyocheong Chae. (2023) 1 Case of a Chronic Atopic Dermatitis Patient Who Improved with a Combined Korean Medicine: Focusing on Yang-geum-hwa Pharmacopuncture. Journal of Korean Medical Society of Acupotomology 7:1, pages 40-43.
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Ga-Yul Min, Tae In Kim, Ji-Hye Kim, Won-Kyung Cho, Ju-Hye Yang & Jin-Yeul Ma. (2022) Inhibitory effect of Isatis tinctoria L. water extract on DNCB-induced atopic dermatitis in BALB/c mice and HaCaT cells. Chinese Medicine 17:1.
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Velpula Prasannanjaneyulu, Shweta Nene, Harsha Jain, Rimsha Nooreen, Shivam Otavi, Palak Chitlangya & Saurabh Srivastava. (2022) Old drugs, new tricks: Emerging role of drug repurposing in the management of atopic dermatitis. Cytokine & Growth Factor Reviews 65, pages 12-26.
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Krzysztof Sitko, Marta Bednarek, Jagoda Mantej, Magdalena Trzeciak & Stefan Tukaj. (2021) Circulating heat shock protein 90 (Hsp90) and autoantibodies to Hsp90 are increased in patients with atopic dermatitis. Cell Stress and Chaperones 26:6, pages 1001-1007.
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Ravi Raj Pal, Anish Kumar Maurya, Poonam Parashar & Shubhini A. Saraf. (2020) A Comparative Study of Levocetirizine Loaded Vesicular and Matrix Type System for Topical Application: Appraisal of Therapeutic Potential against Atopic Dermatitis. Journal of Pharmaceutical Innovation 16:3, pages 469-480.
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Kwang Hoon Lee & Chang Ook Park. 2021. Practical Insights into Atopic Dermatitis. Practical Insights into Atopic Dermatitis 133 153 .
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Sara N. Bilimoria & Peter A. Lio. (2020) Biologics for Allergic Dermatologic Diseases. Current Allergy and Asthma Reports 20:8.
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T.H. Andreasen, M.O. Christensen, A.‐S. Halling, A. Egeberg & J.P. Thyssen. (2020) Placebo response in phase 2 and 3 trials of systemic and biological therapies for atopic dermatitis—a systematic review and meta‐analysis. Journal of the European Academy of Dermatology and Venereology 34:6, pages 1143-1150.
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Na-Hee Jeong, Soyoung Lee, Jin Kyeong Choi, Young-Ae Choi, Min-Jong Kim, Hyun-Shik Lee, Tae-Yong Shin, Yong Hyun Jang, Kyung-Sik Song & Sang-Hyun Kim. (2020) Polyozellin alleviates atopic dermatitis-like inflammatory and pruritic responses in activated keratinocytes and mast cells. Biomedicine & Pharmacotherapy 122, pages 109743.
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Koichi Ando, Akihiko Tanaka & Hironori Sagara. (2020) Comparative Efficacy and Safety of Dupilumab and Benralizumab in Patients with Inadequately Controlled Asthma: A Systematic Review. International Journal of Molecular Sciences 21:3, pages 889.
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Dong-Ho Nahm, Young-Min Ye, Yoo Seob Shin, Hae-Sim Park, Myoung-Eun Kim, Byul Kwon, Su-Mi Cho & Jinjoo Han. (2020) Efficacy, Safety, and Immunomodulatory Effect of the Intramuscular Administration of Autologous Total Immunoglobulin G for Atopic Dermatitis: A Randomized Clinical Trial. Allergy, Asthma & Immunology Research 12:6, pages 949.
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Peter H. Schafer, Mary Adams, Gerald Horan, Francesca Truzzi, Alessandra Marconi & Carlo Pincelli. (2019) Apremilast Normalizes Gene Expression of Inflammatory Mediators in Human Keratinocytes and Reduces Antigen-Induced Atopic Dermatitis in Mice. Drugs in R&D 19:4, pages 329-338.
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B. Akinlade, E. Guttman‐Yassky, M. Bruin‐Weller, E.L. SimpsonA. Blauvelt, M.J. CorkE. Prens, P. AsbellE. AkpekJ. CorrenC. Bachert, I. HiranoJ. WeyneA. KorotzerZ. ChenT. HultschX. ZhuJ.D. DavisL. Mannent, J.D. HamiltonA. TeperH. StaudingerE. RizovaG. PirozziN.M.H. GrahamB. ShumelM. ArdeleanuA. Wollenberg. (2019) Conjunctivitis in dupilumab clinical trials. British Journal of Dermatology 181:3, pages 459-473.
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Emma Guttman-Yassky, Ana B. Pavel, Lisa Zhou, Yeriel D. Estrada, Ning Zhang, Hui Xu, Xiangyu Peng, Huei-Chi Wen, Panayiota Govas, Girish Gudi, Vinu CA, Hui Fang, Yacine Salhi, Jonathan Back, Venkateshwar Reddy, Robert Bissonnette, Catherine Maari, Fred Grossman & Gerhard Wolff. (2019) GBR 830, an anti-OX40, improves skin gene signatures and clinical scores in patients with atopic dermatitis. Journal of Allergy and Clinical Immunology 144:2, pages 482-493.e7.
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Yael Renert-Yuval & Emma Guttman-Yassky. (2019) What’s New in Atopic Dermatitis. Dermatologic Clinics 37:2, pages 205-213.
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Leila Ferguson, Masaki Futamura, Efstratios Vakirlis, Reiji Kojima, Hatoko Sasaki, Amanda Roberts & Rintaro Mori. (2018) Leukotriene receptor antagonists for eczema. Cochrane Database of Systematic Reviews 2018:10.
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Na-Ra Han, Phil-Dong Moon, Min-Sun Yoo, Ka-Jung Ryu, Hyung-Min Kim & Hyun-Ja Jeong. (2018) Regulatory effects of chrysophanol, a bioactive compound of AST2017-01 in a mouse model of 2,4-dinitrofluorobenzene-induced atopic dermatitis. International Immunopharmacology 62, pages 220-226.
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Yael Renert-Yuval & Emma Guttman-Yassky. (2018) Monoclonal antibodies for the treatment of atopic dermatitis. Current Opinion in Allergy & Clinical Immunology 18:4, pages 356-364.
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George Man, Li-zhi Hu, Peter M Elias & Mao-qiang Man. (2017) Therapeutic Benefits of Natural Ingredients for Atopic Dermatitis. Chinese Journal of Integrative Medicine 24:4, pages 308-314.
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