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Expert Opinion on Biological Therapy Volume 13, 2013 - Issue 11
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Clinical trials of amyloid-based immunotherapy for Alzheimer's disease: end of beginning or beginning of end?

Yun LiNanjing University School of Medicine, Jinling Hospital, Department of Neurology, 305 East Zhongshan Road, Nanjing 210002, Jiangsu Province, China+86 25 8480 1861; +86 25 8480 5169; [email protected]
,
Yahong LiuNanjing University School of Medicine, Jinling Hospital, Department of Neurology, 305 East Zhongshan Road, Nanjing 210002, Jiangsu Province, China+86 25 8480 1861; +86 25 8480 5169; [email protected]
,
Zhaojun WangNanjing University School of Medicine, Jinling Hospital, Department of Neurology, 305 East Zhongshan Road, Nanjing 210002, Jiangsu Province, China+86 25 8480 1861; +86 25 8480 5169; [email protected]
&
Yongjun JiangNanjing University School of Medicine, Jinling Hospital, Department of Neurology, 305 East Zhongshan Road, Nanjing 210002, Jiangsu Province, China+86 25 8480 1861; +86 25 8480 5169; [email protected]
Pages 1515-1522 | Published online: 22 Sep 2013

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Laia Montoliu-Gaya, Javier Murciano-Calles, Jose C. Martinez & Sandra Villegas. (2017) Towards the improvement in stability of an anti-Aβ single-chain variable fragment, scFv-h3D6, as a way to enhance its therapeutic potential. Amyloid 24:3, pages 167-175.
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Thomas Müller & Paul Foley. (2016) Clinical drug research in chronic central neurodegenerative disorders. Expert Review of Neurotherapeutics 16:5, pages 497-504.
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Francesco Panza, Vincenzo Solfrizzi, Bruno P Imbimbo, Rosanna Tortelli, Andrea Santamato & Giancarlo Logroscino. (2014) Amyloid-based immunotherapy for Alzheimer's disease in the time of prevention trials: the way forward. Expert Review of Clinical Immunology 10:3, pages 405-419.
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Zhihua Qiu & Yimin Dai. (2014) Roadmap of miR-122-related clinical application from bench to bedside. Expert Opinion on Investigational Drugs 23:3, pages 347-355.
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Articles from other publishers (15)

Caterina Vicidomini, Nicola Borbone, Valentina Roviello, Giovanni N. Roviello & Giorgia Oliviero. (2023) Summary of the Current Status of DNA Vaccination for Alzheimer Disease. Vaccines 11:11, pages 1706.
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D. G. Garbuz, O. G. Zatsepina & M. B. Evgen’ev. (2021) Beta Amyloid, Tau Protein, and Neuroinflammation: An Attempt to Integrate Different Hypotheses of Alzheimer’s Disease Pathogenesis. Molecular Biology 55:5, pages 670-682.
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Wen-Hui Ma, Ai-Fang Chen, Xiao-Yang Xie & Yun-Sheng Huang. (2021) Sigma ligands as potent inhibitors of Aβ and AβOs in neurons and promising therapeutic agents of Alzheimer's disease. Neuropharmacology 190, pages 108342.
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Thomas Müller. 2020. Diagnosis and Management in Dementia. Diagnosis and Management in Dementia 547 558 .
Hyunjung Baek, Chan-ju Lee, Da Bin Choi, Nam-sik Kim, Yong-Suk Kim, Young Jun Ye, Youn-Sub Kim, Jin Su Kim, Insop Shim & Hyunsu Bae. (2018) Bee venom phospholipase A2 ameliorates Alzheimer’s disease pathology in Aβ vaccination treatment without inducing neuro-inflammation in a 3xTg-AD mouse model. Scientific Reports 8:1.
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M. Dieterich & A. Zwergal. (2018) Interdisziplinäre Herausforderungen in der NeuromedizinInterdisciplinary challenges in neuromedicine. Der Nervenarzt 89:10, pages 1081-1082.
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Barbara Mroczko, Magdalena Groblewska, Ala Litman-Zawadzka, Johannes Kornhuber & Piotr Lewczuk. (2017) Amyloid β oligomers (AβOs) in Alzheimer’s disease. Journal of Neural Transmission 125:2, pages 177-191.
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Bahareh Eftekharzadeh, Bradley T. Hyman & Susanne Wegmann. (2016) Structural studies on the mechanism of protein aggregation in age related neurodegenerative diseases. Mechanisms of Ageing and Development 156, pages 1-13.
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Laia Montoliu-Gaya & Sandra Villegas. (2016) A β -Immunotherapeutic strategies: a wide range of approaches for Alzheimer's disease treatment . Expert Reviews in Molecular Medicine 18.
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Jack Losso. 2015. The Maillard Reaction Reconsidered. The Maillard Reaction Reconsidered 283 312 .
Marta Westwood & Alastair Lawson. (2015) Opportunities for Conformation-Selective Antibodies in Amyloid-Related Diseases. Antibodies 4:3, pages 170-196.
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Douglas G. Walker, Alexis M. Whetzel, Geidy Serrano, Lucia I. Sue, Thomas G. Beach & Lih-Fen Lue. (2015) Association of CD33 polymorphism rs3865444 with Alzheimer's disease pathology and CD33 expression in human cerebral cortex. Neurobiology of Aging 36:2, pages 571-582.
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M. S. Kukharsky, R. K. Ovchinnikov & S. O. Bachurin. (2015) Molecular aspects of the pathogenesis and current approaches to pharmacological correction of Alzheimer?s disease. Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova 115:6, pages 103.
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Hyun Yang & Dong Seok Kim. 2015. Peptide and Protein Vaccines. Peptide and Protein Vaccines 1 14 .
Hui Jin, Weixi Wang, Shanshan Zhao, Weina Yang, Yihua Qian, Ning Jia & Gaifeng Feng. (2014) Aβ-HBc virus-like particles immunization without additional adjuvant ameliorates the learning and memory and reduces Aβ deposit in PDAPP mice. Vaccine 32:35, pages 4450-4456.
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