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Biological therapies for the treatment of cutaneous wounds: Phase III and launched therapies

, BA, , PhD, , MD, , MD, , MD, , MD, , MD, , MD & , MD show all
Pages 1523-1541 | Published online: 05 Oct 2013

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Ovidio Catanzano, Fabiana Quaglia & Joshua S. Boateng. (2021) Wound dressings as growth factor delivery platforms for chronic wound healing. Expert Opinion on Drug Delivery 18:6, pages 737-759.
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Hsiang-Hao Hsu, Aline Yen Ling Wang, Charles Yuen Yung Loh, Ashwin Alke Pai & Huang-Kai Kao. (2022) Therapeutic Potential of Exosomes Derived from Diabetic Adipose Stem Cells in Cutaneous Wound Healing of db/db Mice. Pharmaceutics 14:6, pages 1206.
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Yuan Li, Yucong Li, Linlong Li, Haixing Wang, Bin Wang, Lu Feng, Sien Lin & Gang Li. (2022) The emerging translational potential of GDF11 in chronic wound healing. Journal of Orthopaedic Translation 34, pages 113-120.
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Marta Torregrossa, Ainur Kakpenova, Jan C. Simon & Sandra Franz. (2021) Modulation of macrophage functions by ECM-inspired wound dressings – a promising therapeutic approach for chronic wounds. Biological Chemistry 402:11, pages 1289-1307.
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Angela L.F. Gibson, James H. HolmesIVIV, Jeffrey W. Shupp, David Smith, Victor Joe, Joshua Carson, Jeffrey Litt, Steven Kahn, Tracee Short, Leopoldo Cancio, Julie Rizzo, Jeffrey E. Carter, Kevin Foster, Mary A. Lokuta, Allen R. Comer, Janice M. Smiell & B. Lynn Allen-Hoffmann. (2021) A phase 3, open-label, controlled, randomized, multicenter trial evaluating the efficacy and safety of StrataGraft® construct in patients with deep partial-thickness thermal burns. Burns 47:5, pages 1024-1037.
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Xujie Wang, Kuo Shen, Jing Wang, Kaituo Liu, Gaofeng Wu, Yan Li, Liang Luo, Zhao Zheng & Dahai Hu. (2020) Hypoxic preconditioning combined with curcumin promotes cell survival and mitochondrial quality of bone marrow mesenchymal stem cells, and accelerates cutaneous wound healing via PGC-1α/SIRT3/HIF-1α signaling. Free Radical Biology and Medicine 159, pages 164-176.
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Ursula Hopfner, Zeshaan N. Maan, Michael S. Hu, Matthias M. Aitzetmüller, Maximilian Zaussinger, Manuela Kirsch, Hans-Günther Machens & Dominik Duscher. (2020) Deferoxamine enhances the regenerative potential of diabetic Adipose Derived Stem Cells. Journal of Plastic, Reconstructive & Aesthetic Surgery 73:9, pages 1738-1746.
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Satiesh Kumar Ramadass, Lone Saquib Nazir, Ramar Thangam, Ramesh Kannan Perumal, I. Manjubala, Balaraman Madhan & Shanmuganathan Seetharaman. (2019) Type I collagen peptides and nitric oxide releasing electrospun silk fibroin scaffold: A multifunctional approach for the treatment of ischemic chronic wounds. Colloids and Surfaces B: Biointerfaces 175, pages 636-643.
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Melanie Rodrigues, Nina Kosaric, Clark A. Bonham & Geoffrey C. Gurtner. (2019) Wound Healing: A Cellular Perspective. Physiological Reviews 99:1, pages 665-706.
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Anne DallasArtem TrotsyukHeini IlvesClark A. BonhamMelanie RodriguesKarl EngelJanos A. BarreraNina KosaricZachary A. Stern-BuchbinderAleksandr WhiteKenneth J. MandellPaula T. HammondJonathan MansbridgeSumedha JayasenaGeoffrey C. GurtnerBrian H. Johnston. (2019) Acceleration of Diabetic Wound Healing with PHD2- and miR-210-Targeting Oligonucleotides. Tissue Engineering Part A 25:1-2, pages 44-54.
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Matthias M. Aitzetmüller, Hans-Günther Machens & Dominik Duscher. 2019. Regenerative Medicine and Plastic Surgery. Regenerative Medicine and Plastic Surgery 27 38 .
Matthias M. Aitzetmüller, Elizabeth A. Brett, Matthias Sauter & Dominik Duscher. 2019. Regenerative Medicine and Plastic Surgery. Regenerative Medicine and Plastic Surgery 7 15 .
Saritphat Orrapin & Kittipan Rekasem. (2018) Role of Topical Biological Therapies and Dressings in Healing Ischemic Wounds. The International Journal of Lower Extremity Wounds 17:4, pages 236-246.
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Alberto Piaggesi, Severin Låuchli, Franco Bassetto, Thomas Biedermann, Alexandra Marques, Bijan Najafi, Ilaria Palla, Carlotta Scarpa, Diane Seimetz, Isotta Triulzi, Giuseppe Turchetti & Annegret Vaggelas. (2018) Advanced therapies in wound management: cell and tissue based therapies, physical and bio-physical therapies smart and IT based technologies. Journal of Wound Care 27:Sup6a, pages S1-S137.
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Ghislain Opdenakker, Jo Van Damme & Jan Jeroen Vranckx. (2018) Immunomodulation as Rescue for Chronic Atonic Skin Wounds. Trends in Immunology 39:4, pages 341-354.
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Matthew Davenport & Laura E. Dickinson. 2021. Chronic Wounds, Wound Dressings and Wound Healing. Chronic Wounds, Wound Dressings and Wound Healing 51 74 .
Matthias M. Aitzetmüller, Hans-Günther Machens & Dominik Duscher. 2021. Chronic Wounds, Wound Dressings and Wound Healing. Chronic Wounds, Wound Dressings and Wound Healing 37 49 .
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Elton Mathias & Madhu Srinivas Murthy. (2017) Pediatric Thermal Burns and Treatment: A Review of Progress and Future Prospects. Medicines 4:4, pages 91.
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Lígia Reis Moura Estevão, Ricardo Santos Simões, Puebla Cassini-Vieira, Maria Cecilia Campos Canesso, Lucíola da Silva Barcelos, Milene Alvarenga Rachid, Cláudio Augusto Gomes da Câmara & Joaquim Evêncio-Neto. (2017) Schinus terebinthifolius Raddi ( Aroeira) leaves oil attenuates inflammatory responses in cutaneous wound healing in mice. Acta Cirurgica Brasileira 32:9, pages 726-735.
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Jasmine HoClaire WalshDominic YueAlan DardikUmber Cheema. (2017) Current Advancements and Strategies in Tissue Engineering for Wound Healing: A Comprehensive Review. Advances in Wound Care 6:6, pages 191-209.
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Carlos R Padovani. (2017) Hydroalcoholic Extract from Copaifera Langsdorffii Has Skin Wound Healing Activity in Rats. International Journal of Complementary & Alternative Medicine 6:1.
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Pietro Gentile, Maria Giovanna Scioli, Alessandra Bielli, Augusto Orlandi & Valerio Cervelli. (2017) Concise Review: The Use of Adipose-Derived Stromal Vascular Fraction Cells and Platelet Rich Plasma in Regenerative Plastic Surgery. Stem Cells 35:1, pages 117-134.
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Aksone NouvongAaron M. Ambrus, Ellen R. Zhang, Lucas HultmanHilary A. Coller. (2016) Reactive oxygen species and bacterial biofilms in diabetic wound healing. Physiological Genomics 48:12, pages 889-896.
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Laura E. Dickinson & Sharon Gerecht. (2016) Engineered Biopolymeric Scaffolds for Chronic Wound Healing. Frontiers in Physiology 7.
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Robert C. Rennert, Michael Januszyk, Michael Sorkin, Melanie Rodrigues, Zeshaan N. Maan, Dominik Duscher, Alexander J. Whittam, Revanth Kosaraju, Michael T. Chung, Kevin Paik, Alexander Y. Li, Michael Findlay, Jason P. Glotzbach, Atul J. Butte & Geoffrey C. Gurtner. (2016) Microfluidic single-cell transcriptional analysis rationally identifies novel surface marker profiles to enhance cell-based therapies. Nature Communications 7:1.
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Alexander J. WhittamZeshaan N. MaanDominik DuscherVictor W. WongJanos A. BarreraMichael JanuszykGeoffrey C. Gurtner. (2016) Challenges and Opportunities in Drug Delivery for Wound Healing. Advances in Wound Care 5:2, pages 79-88.
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Gamaliel Benítez-Arvízu, Ícela Palma-Lara, René Vazquez-Campos, Raimundo Alfonso Sesma-Villalpando, Alberto Parra-Barrera & Gisela Gutiérrez-Iglesias. (2015) Autologous mesenchymal stem cells and cutaneous autograft as a treatment for chronic ulcer secondary to diabetes mellitus 2. Cirugía y Cirujanos (English Edition) 83:6, pages 532-536.
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R Tevlin, D Atashroo, D Duscher, A Mc Ardle, G C Gurtner, D C Wan & M T Longaker. (2015) Impact of surgical innovation on tissue repair in the surgical patient. British Journal of Surgery 102:2, pages e41-e55.
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Elizabeth R Zielins, David A Atashroo, Zeshaan N Maan, Dominik Duscher, Graham G Walmsley, Michael Hu, Kshemendra Senarath-Yapa, Adrian McArdle, Ruth Tevlin, Taylor Wearda, Kevin J Paik, Christopher Duldulao, Wan Xing Hong, Geoffrey C Gurtner & Michael T Longaker. (2014) Wound healing: an update. Regenerative Medicine 9:6, pages 817-830.
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