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T-cell co-stimulatory blockade in transplantation: two steps forward one step back!

, MD PhD & , MD
Pages 1557-1568 | Published online: 01 Oct 2013

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Zhi Yang Ng, Charlotte Read, Josef M Kurtz & Curtis L Cetrulo$suffix/text()$suffix/text(). (2015) Memory T Cells in Vascularized Composite Allotransplantation. Vascularized Composite Allotransplantation 2:4, pages 75-79.
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Bhavna Chopra & Kalathil K Sureshkumar. (2014) Co-stimulatory blockade with belatacept in kidney transplantation. Expert Opinion on Biological Therapy 14:5, pages 563-567.
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Yuan Chang, Mengda Xu, Yu Zhang, Xiao Chen, Yixuan Sheng, Menghao Tao, Hang Zhang, Zhenyu Xu, Shengshou Hu & Jiangping Song. (2023) Ruxolitinib attenuates acute rejection and can serve as an immune induction therapy in heart transplantation. Clinical Immunology 257, pages 109851.
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Dimitrios Giannis, Dimitrios Moris & Linda C. Cendales. (2020) Costimulation Blockade in Vascularized Composite Allotransplantation. Frontiers in Immunology 11.
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Poulami Majumder, Yichuan Zhang, Marcos Iglesias, Lixin Fan, James A. Kelley, Caroline Andrews, Nimit Patel, Jason R. Stagno, Byoung Chol Oh, Georg J. Furtmüller, Christopher C. Lai, Yun‐Xing Wang, Gerald Brandacher, Giorgio Raimondi & Joel P. Schneider. (2020) Multiphase Assembly of Small Molecule Microcrystalline Peptide Hydrogel Allows Immunomodulatory Combination Therapy for Long‐Term Heart Transplant Survival. Small 16:38, pages 2002791.
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Byoung Chol Oh, Georg J. Furtmüller, Madeline L. Fryer, Yinan Guo, Franka Messner, Johanna Krapf, Stefan Schneeberger, Damon S. Cooney, W.P. Andrew Lee, Giorgio Raimondi & Gerald Brandacher. (2020) Vascularized composite allotransplantation combined with costimulation blockade induces mixed chimerism and reveals intrinsic tolerogenic potential. JCI Insight 5:7.
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Stella H. Khiew, Jinghui Yang, James S. Young, Jianjun Chen, Qiang Wang, Dengping Yin, Vinh Vu, Michelle L. Miller, Roger Sciammas, Maria-Luisa Alegre & Anita S. Chong. (2017) CTLA4-Ig in combination with FTY720 promotes allograft survival in sensitized recipients. JCI Insight 2:9.
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Zhi Yang Ng, Alexandre G. Lellouch, Tessa Drijkoningen, Irene A. Chang, David H. Sachs & Curtis L. CetruloJr.Jr.. (2017) Vascularized Composite Allotransplantation—An Emerging Concept for Burn Reconstruction. Journal of Burn Care & Research 38:6, pages 371-378.
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Leonardo V. Riella, Arjang Djamali & Julio Pascual. (2017) Chronic allograft injury: Mechanisms and potential treatment targets. Transplantation Reviews 31:1, pages 1-9.
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Julia C. Arciero, Andrew Maturo, Anirudh Arun, Byoung Chol Oh, Gerald Brandacher & Giorgio Raimondi. (2016) Combining Theoretical and Experimental Techniques to Study Murine Heart Transplant Rejection. Frontiers in Immunology 7.
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Wen-Tao He, Li-Min Zhang, Chao Li, Shu-Yuan Li, Zuo-Chuan Ding, Ze-Min Fang, Fan-Ying Meng, Zhonghua Klaus Chen & Ping Zhou. (2016) Short-term MyD88 inhibition ameliorates cardiac graft rejection and promotes donor-specific hyporesponsiveness of skin grafts in mice. Transplant International 29:8, pages 941-952.
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J.S. Young, J. Chen, M.L. Miller, V. Vu, C. Tian, J.J. Moon, M.-L. Alegre, R. Sciammas & A.S. Chong. (2016) Delayed Cytotoxic T Lymphocyte–Associated Protein 4–Immunoglobulin Treatment Reverses Ongoing Alloantibody Responses and Rescues Allografts From Acute Rejection. American Journal of Transplantation 16:8, pages 2312-2323.
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Sandeep K. MallipattuJohn C. He. (2016) The podocyte as a direct target for treatment of glomerular disease?. American Journal of Physiology-Renal Physiology 311:1, pages F46-F51.
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Andrea B?hr, Tobias K?ser, Elisabeth Kemter, Wilhelm Gerner, Mayuko Kurome, Wiebke Baars, Nadja Herbach, Kirsti Witter, Annegret W?nsch, Stephanie C. Talker, Barbara Kessler, Hiroshi Nagashima, Armin Saalm?ller, Reinhard Schwinzer, Eckhard Wolf & Nikolai Klymiuk. (2016) Ubiquitous LEA29Y Expression Blocks T Cell Co-Stimulation but Permits Sexual Reproduction in Genetically Modified Pigs. PLOS ONE 11:5, pages e0155676.
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David H. Gardner, Louisa E. Jeffery, Blagoje Soskic, Zoe Briggs, Tie Zheng Hou, Karim Raza & David M. Sansom. (2015) 1,25(OH)2D3 Promotes the Efficacy of CD28 Costimulation Blockade by Abatacept. The Journal of Immunology 195:6, pages 2657-2665.
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Tae-Hyun Yoo & Alessia Fornoni. (2015) Nonimmunologic targets of immunosuppressive agents in podocytes. Kidney Research and Clinical Practice 34:2, pages 69-75.
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Joanna N. Hooten & Sarah A. Myers. 2015. Advances in Transplant Dermatology. Advances in Transplant Dermatology 1 17 .
S.M. Krummey & M.L. Ford. (2014) Braking Bad: Novel Mechanisms of CTLA-4 Inhibition of T Cell Responses. American Journal of Transplantation 14:12, pages 2685-2690.
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Vikas Satyananda & Ron Shapiro. (2014) Belatacept in kidney transplantation. Current Opinion in Organ Transplantation 19:6, pages 573-577.
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D. Gardner, L.E. Jeffery & D.M. Sansom. (2014) Understanding the CD28/CTLA-4 (CD152) Pathway and Its Implications for Costimulatory Blockade. American Journal of Transplantation 14:9, pages 1985-1991.
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Sanjeev Kumar, Jing Liu & Andrew P. McMahon. (2014) Defining the Acute Kidney Injury and Repair Transcriptome. Seminars in Nephrology 34:4, pages 404-417.
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