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Advances in adenovirus-mediated p53 cancer gene therapy

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Pages 1569-1583 | Published online: 10 Oct 2013

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Guang-xia Chen, Shu Zhang, Xiao-hua He, Shi-yu Liu, Chao Ma & Xiao-Ping Zou. (2014) Clinical utility of recombinant adenoviral human p53 gene therapy: current perspectives. OncoTargets and Therapy 7, pages 1901-1909.
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Bo Li, Ning Gao, Zhuang Zhang, Qian‐Ming Chen, Long‐Jiang Li & Yi Li. (2017) Historical and Clinical Experiences of Gene Therapy for Solid Cancers in China. Genes 8:3, pages 85.
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Jiao Zhou, Qiu-Mei Yao, Jin-Lan Li, Yan Chang, Ting Li, Wen-Ling Han, Hong-Ping Wu, Lin-Fang Li, Qi-Jun Qian & Guo-Rui Ruan. (2016) Synergistic antitumor activity of triple-regulated oncolytic adenovirus with VSTM1 and daunorubicin in leukemic cells. Apoptosis 21:10, pages 1179-1190.
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Kathleen F Pirollo, John Nemunaitis, Po Ki Leung, Robert Nunan, Jana Adams & Esther H Chang. (2016) Safety and Efficacy in Advanced Solid Tumors of a Targeted Nanocomplex Carrying the p53 Gene Used in Combination with Docetaxel: A Phase 1b Study. Molecular Therapy 24:9, pages 1697-1706.
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Hiroshi Tazawa, Shunsuke Kagawa & Toshiyoshi Fujiwara. 2016. Current Strategies in Cancer Gene Therapy. Current Strategies in Cancer Gene Therapy 1 15 .
Bruna de Andrade Pereira, Leoneide E. Maduro Bouillet, Natalia A. Dorigo, Cornel Fraefel & Oscar Bruna-Romero. (2015) Adenovirus Specific Pre-Immunity Induced by Natural Route of Infection Does Not Impair Transduction by Adenoviral Vaccine Vectors in Mice. PLOS ONE 10:12, pages e0145260.
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Maolan Li, Fei Zhang, Xu'an Wang, Xiangsong Wu, Bingtai Zhang, Ning Zhang, Wenguang Wu, Zheng Wang, Hao Weng, Shibo Liu, Guofeng Gao, Jiasheng Mu, Yijun Shu, Runfa Bao, Yang Cao, Jianhua Lu, Jun Gu, Jian Zhu & Yingbin Liu. (2015) Magnolol inhibits growth of gallbladder cancer cells through the p53 pathway. Cancer Science 106:10, pages 1341-1350.
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XIONG ZHANG, DONG-DONG QI, TING-TING ZHANG, QING-XIN CHEN, GUANG-ZHI WANG, GUANG-YU SUI, XUE-WEI HAO, SHOULI SUN, XUE SONG & YING-LI CHEN. (2015) Antitumor activity of adenoviral vector containing T42 and 4xT42 peptide gene through inducing apoptosis of tumor cells and suppressing angiogenesis. Molecular Medicine Reports 11:3, pages 2083-2091.
Crossref
Haixi Mu, Na Wang, Lijuan Zhao, Shuman Li, Qianqian Li, Ling Chen, Xinrong Luo, Zhu Qiu, Lili Li, Guosheng Ren, Yongzhu Xu, Xiangyang Zhou & Tingxiu Xiang. (2015) Methylation of PLCD1 and adenovirus-mediated PLCD1 overexpression elicits a gene therapy effect on human breast cancer. Experimental Cell Research 332:2, pages 179-189.
Crossref
Shunsuke Iizuka, Fuminori Sakurai, Kahori Shimizu, Kazuo Ohashi, Shin-ichiro Nakamura, Masashi Tachibana & Hiroyuki Mizuguchi. (2015) Evaluation of Transduction Properties of an Adenovirus Vector in Neonatal Mice. BioMed Research International 2015, pages 1-10.
Crossref
Mireille Happy, Jordan Dejoie, Cynthia K. Zajac, Briseida Cortez, Karabi Chakraborty, Joseph Aderemi & Moira Sauane. (2015) Sigma 1 Receptor antagonist potentiates the anti-cancer effect of p53 by regulating ER stress, ROS production, Bax levels, and caspase-3 activation. Biochemical and Biophysical Research Communications 456:2, pages 683-688.
Crossref
C. Serguera & A.-P. Bemelmans. (2014) Gene therapy of the central nervous system: General considerations on viral vectors for gene transfer into the brain. Revue Neurologique 170:12, pages 727-738.
Crossref
Michael J. Duffy, Naoise C. Synnott, Patricia M. McGowan, John Crown, Darran O’Connor & William M. Gallagher. (2014) p53 as a target for the treatment of cancer. Cancer Treatment Reviews 40:10, pages 1153-1160.
Crossref
Christelle En Lin Chua, Shu Ning Chan & Bor Luen Tang. (2014) Non-Cell Autonomous or Secretory Tumor Suppression. Journal of Cellular Physiology 229:10, pages 1346-1352.
Crossref
Masashi Idogawa, Tomoko Ohashi, Jun Sugisaka, Yasushi Sasaki, Hiromu Suzuki & Takashi Tokino. (2014) Array-based genome-wide RNAi screening to identify shRNAs that enhance p53-related apoptosis in human cancer cells. Oncotarget 5:17, pages 7540-7548.
Crossref
Juan Liu, Cen Zhang & Zhaohui Feng. (2014) Tumor suppressor p53 and its gain-of-function mutants in cancer. Acta Biochimica et Biophysica Sinica 46:3, pages 170-179.
Crossref
Chang-quan Ling, Li-na Wang, Yuan Wang, Yuan-hui Zhang, Zi-fei Yin, Meng Wang & Chen Ling. (2014) The roles of traditional Chinese medicine in gene therapy. Journal of Integrative Medicine 12:2, pages 67-75.
Crossref
Amy Lee Bredlau & David N. Korones. 2014. 235 259 .

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