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Drug Evaluations

Elotuzumab: a novel anti-CS1 monoclonal antibody for the treatment of multiple myeloma

, MD, , MD, , MD MPP & , MD
Pages 1731-1740 | Published online: 23 Oct 2013

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Sagar Lonial, Jonathan Kaufman, Donna Reece, Maria-Victoria Mateos, Jacob Laubach & Paul Richardson. (2016) Update on elotuzumab, a novel anti-SLAMF7 monoclonal antibody for the treatment of multiple myeloma. Expert Opinion on Biological Therapy 16:10, pages 1291-1301.
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Huaijian Guo, Mario-Ernesto Cruz-Munoz, Ning Wu, Michael Robbins & André Veillette. (2015) Immune Cell Inhibition by SLAMF7 Is Mediated by a Mechanism Requiring Src Kinases, CD45, and SHIP-1 That Is Defective in Multiple Myeloma Cells. Molecular and Cellular Biology 35:1, pages 41-51.
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Yi-Chang Liu, Susann Szmania & Frits van Rhee. (2014) Profile of elotuzumab and its potential in the treatment of multiple myeloma. Blood and Lymphatic Cancer: Targets and Therapy 4, pages 15-27.
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Claudia Andreu-Vieyra & James R Berenson. (2014) Carfilzomib in multiple myeloma. Expert Opinion on Biological Therapy 14:11, pages 1685-1699.
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Articles from other publishers (25)

Lei Huang, Jingyu Zhang, Elizabeth Punnoose, Zhenyu Xiao & Wenjin Li. (2023) Current status of drug development for patients with multiple myeloma: a review of comparison in China and the rest of world. Antibody Therapeutics.
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Jong Lyul Lee, Seon Ae Roh, Chan Wook Kim, Yi Hong Kwon, Ye Jin Ha, Seon-Kyu Kim, Seon-Young Kim, Dong-Hyung Cho, Yong Sung Kim & Jin Cheon Kim. (2019) Clinical assessment and identification of immuno-oncology markers concerning the 19-gene based risk classifier in stage IV colorectal cancer. World Journal of Gastroenterology 25:11, pages 1341-1354.
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Shuo Li, Xiang-Yu Meng, Souraka Tapara Dramani Maman, Yong-Nong Xiao & Sheng Li. (2018) Lenalidomide and Low Dose Dexamethasone Plus Elotuzumab or Carfilzomib for Relapsed or Refractory Multiple Myeloma: A Comparison of Progression-Free Survival with Reconstructed Individual Participant Data. BioMed Research International 2018, pages 1-6.
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Sara Gandolfi, Claudia Paba Prada & Paul G. Richardson. (2018) How I treat the young patient with multiple myeloma. Blood 132:11, pages 1114-1124.
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Zhangyong Xia, Mingliang Gu, Xiaodong Jia, Xiaoting Wang, Chunxia Wu, Jiangwen Guo, Liyong Zhang, Yifeng Du & Jiyue Wang. (2018) Integrated DNA methylation and gene expression analysis identifies SLAMF7 as a key regulator of atherosclerosis. Aging 10:6, pages 1324-1337.
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David Ritchie & Marco Colonna. (2018) Mechanisms of Action and Clinical Development of Elotuzumab. Clinical and Translational Science 11:3, pages 261-266.
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Kazunori Murata, Samuel I McCash, Brittany Carroll, Alexander M Lesokhin, Hani Hassoun, Nikoletta Lendvai, Neha S Korde, Sham Mailankody, Heather J Landau, Guenther Koehne, David J Chung, Sergio A Giralt, Lakshmi V Ramanathan & Ola Landgren. (2018) Treatment of multiple myeloma with monoclonal antibodies and the dilemma of false positive M-spikes in peripheral blood. Clinical Biochemistry 51, pages 66-71.
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Isabel Corraliza-Gorjón, Beatriz Somovilla-Crespo, Silvia Santamaria, Jose A. Garcia-Sanz & Leonor Kremer. (2017) New Strategies Using Antibody Combinations to Increase Cancer Treatment Effectiveness. Frontiers in Immunology 8.
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Michael Boyiadzis, Michael R. Bishop, Rafat Abonour, Kenneth C. Anderson, Stephen M. Ansell, David Avigan, Lisa Barbarotta, Austin John Barrett, Koen Van Besien, P. Leif Bergsagel, Ivan Borrello, Joshua Brody, Jill Brufsky, Mitchell Cairo, Ajai Chari, Adam Cohen, Jorge Cortes, Stephen J. Forman, Jonathan W. Friedberg, Ephraim J. Fuchs, Steven D. Gore, Sundar Jagannath, Brad S. Kahl, Justin Kline, James N. Kochenderfer, Larry W. Kwak, Ronald Levy, Marcos de Lima, Mark R. Litzow, Anuj Mahindra, Jeffrey Miller, Nikhil C. Munshi, Robert Z. Orlowski, John M. Pagel, David L. Porter, Stephen J. Russell, Karl Schwartz, Margaret A. Shipp, David Siegel, Richard M. Stone, Martin S. Tallman, John M. Timmerman, Frits Van Rhee, Edmund K. Waller, Ann Welsh, Michael Werner, Peter H. Wiernik & Madhav V. Dhodapkar. (2016) The Society for Immunotherapy of Cancer consensus statement on immunotherapy for the treatment of hematologic malignancies: multiple myeloma, lymphoma, and acute leukemia. Journal for ImmunoTherapy of Cancer 4:1.
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Noopur S. Raje, Edward A. FaberJrJr, Paul G. Richardson, Gary Schiller, Raymond J. Hohl, Adam D. Cohen, Andres Forero, Susan Carpenter, Tuan S. Nguyen, Ilaria Conti, Christopher J. Kaiser, Damien M. Cronier, James E. Wooldridge & Kenneth C. Anderson. (2016) Phase 1 Study of Tabalumab, a Human Anti-B-Cell Activating Factor Antibody, and Bortezomib in Patients with Relapsed/Refractory Multiple Myeloma. Clinical Cancer Research 22:23, pages 5688-5695.
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Ol'ga Mikhailovna Votyakova. (2016) Elotuzumab for Treatment of Multiple Myeloma (Literature Review). Clinical oncohematology 9:4, pages 438-445.
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Sagar Lonial. (2016) Monoclonal Antibodies for the Treatment of Myeloma. The Cancer Journal 22:1, pages 3-6.
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Jana Filipova, Lucie Rihova, Pavla Vsianska, Zuzana Kufova, Elena Kryukova, Fedor Kryukov & Roman Hajek. (2015) Flow cytometry in immunoglobulin light chain amyloidosis: Short review. Leukemia Research 39:11, pages 1131-1136.
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Giada Bianchi & Kenneth C. Anderson. 2015. Targeted Therapy in Translational Cancer Research. Targeted Therapy in Translational Cancer Research 145 156 .
Andrew T. Hutchinson, Darren R. Jones & Robert L. Raison. (2015) Preclinical and clinical development of an anti-kappa free light chain mAb for multiple myeloma. Molecular Immunology 67:2, pages 89-94.
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Nitya S. Ramadoss, Andrew D. Schulman, Sei-hyun Choi, David T. Rodgers, Stephanie A. Kazane, Chan Hyuk Kim, Brian R. Lawson & Travis S. Young. (2015) An Anti-B Cell Maturation Antigen Bispecific Antibody for Multiple Myeloma. Journal of the American Chemical Society 137:16, pages 5288-5291.
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Paul G Richardson, Philippe Moreau, Jacob P Laubach, Neeraj Gupta, Ai-Min Hui, Kenneth C Anderson, Jesús F San Miguel & Shaji Kumar. (2015) The investigational proteasome inhibitor ixazomib for the treatment of multiple myeloma. Future Oncology 11:8, pages 1153-1168.
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Marco Rossi, Teresa Calimeri, Pierosandro Tagliaferri & Pierfrancesco Tassone. (2015) Multiple myeloma-related bone disease: state-of-art and next future treatments. International Journal of Hematologic Oncology 4:1, pages 33-47.
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J Bae, R Prabhala, A Voskertchian, A Brown, C Maguire, P Richardson, G Dranoff, K C Anderson & N C Munshi. (2014) A multiepitope of XBP1, CD138 and CS1 peptides induces myeloma-specific cytotoxic T lymphocytes in T cells of smoldering myeloma patients. Leukemia 29:1, pages 218-229.
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Maria M. Picken & Kevin Barton. 2015. Amyloid and Related Disorders. Amyloid and Related Disorders 489 505 .
Paul G. Richardson, Jacob P. Laubach, Nikhil C. Munshi & Kenneth C. Anderson. (2014) Early or delayed transplantation for multiple myeloma in the era of novel therapy: does one size fit all?. Hematology 2014:1, pages 255-261.
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Marjolein van Driel & Johannes P.T.M. van Leeuwen. (2014) Cancer and bone: A complex complex. Archives of Biochemistry and Biophysics 561, pages 159-166.
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Elias K. Mai & Hartmut Goldschmidt. (2014) Multiples Myelom. best practice onkologie 9:5, pages 6-15.
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Heinz LudwigPieter SonneveldFaith DaviesJoan BladéMario BoccadoroMichele CavoGareth MorganJavier de la RubiaMichel DelforgeMeletios DimopoulosHermann EinseleThierry FaconHartmut GoldschmidtPhilippe MoreauHareth NahiTorben PlesnerJesús San-MiguelRoman HajekPia Sondergeld & Antonio Palumbo. (2014) European Perspective on Multiple Myeloma Treatment Strategies in 2014. The Oncologist 19:8, pages 829-844.
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Philippe Moreau & Cyrille Touzeau. (2014) Elotuzumab for the treatment of multiple myeloma. Future Oncology 10:6, pages 949-956.
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