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Expert Opinion on Biological Therapy Volume 14, 2014 - Issue 9
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Adenoviral vector-mediated gene therapy for gliomas: coming of age

Maria G CastroUniversity of Michigan Medical School, Department of Neurosurgery, 4570 MSRB II, 1150 West Medical Center Drive, Ann Arbor, MI 48109-5689, USA+734 764 0850; +734 764 7051; [email protected];University of Michigan Medical School, Department of Cell and Developmental Biology, Ann Arbor, MI, USA
, PhD,
Marianela CandolfiUniversity of Buenos Aires, Instituto de Investigaciones Biomédicas (INBIOMED), School of Medicine, CABA, Argentina
, PhD,
Thomas J WilsonUniversity of Michigan Medical School, Department of Neurosurgery, 4570 MSRB II, 1150 West Medical Center Drive, Ann Arbor, MI 48109-5689, USA+734 764 0850; +734 764 7051; [email protected]
, MD,
Alexandra CalinescuUniversity of Michigan Medical School, Department of Neurosurgery, 4570 MSRB II, 1150 West Medical Center Drive, Ann Arbor, MI 48109-5689, USA+734 764 0850; +734 764 7051; [email protected]
, PhD,
Christopher ParanUniversity of Michigan Medical School, Department of Neurosurgery, 4570 MSRB II, 1150 West Medical Center Drive, Ann Arbor, MI 48109-5689, USA+734 764 0850; +734 764 7051; [email protected]
, MSc,
Neha KamranUniversity of Michigan Medical School, Department of Neurosurgery, 4570 MSRB II, 1150 West Medical Center Drive, Ann Arbor, MI 48109-5689, USA+734 764 0850; +734 764 7051; [email protected]
, PhD,
Carl KoschmannUniversity of Michigan Hospital, Division of Pediatric Hematology and Oncology, Ann Arbor, MI, USA
, MD,
Mariela A Moreno-AyalaUniversity of Buenos Aires, Instituto de Investigaciones Biomédicas (INBIOMED), School of Medicine, CABA, Argentina
, BSc,
Hikmat AssiUniversity of Michigan Medical School, Department of Neurosurgery, 4570 MSRB II, 1150 West Medical Center Drive, Ann Arbor, MI 48109-5689, USA+734 764 0850; +734 764 7051; [email protected]
, PhD &
Pedro R LowensteinUniversity of Michigan Medical School, Department of Neurosurgery, 4570 MSRB II, 1150 West Medical Center Drive, Ann Arbor, MI 48109-5689, USA+734 764 0850; +734 764 7051; [email protected];University of Michigan Medical School, Department of Cell and Developmental Biology, Ann Arbor, MI, USA
, MD PhD show all
Pages 1241-1257 | Published online: 29 Apr 2014

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Eun-Joo Shin, Sung Hoon Lee, Naveen Sharma, Bao Trong Nguyen, Yoon Hee Chung, Sang Won Kang, Seung-Yeol Nah, Yu Jeung Lee, Toshitaka Nabeshima, Ji Hoon Jeong & Hyoung-Chun Kim. (2021) An adenoviral vector encoded with the GPx-1 gene attenuates memory impairments induced by β-amyloid (1-42) in GPx-1 KO mice via activation of M1 mAChR-mediated signalling. Free Radical Research 55:1, pages 11-25.
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Antonela S Asad, Alejandro J Nicola Candia, Nazareno Gonzalez, Camila F Zuccato, Adriana Seilicovich & Marianela Candolfi. (2020) The role of the prolactin receptor pathway in the pathogenesis of glioblastoma: what do we know so far?. Expert Opinion on Therapeutic Targets 24:11, pages 1121-1133.
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Adam M. Swartz, Steven H. Shen, Miguel A. Salgado, Kendra L. Congdon & Luis Sanchez-Perez. (2018) Promising vaccines for treating glioblastoma. Expert Opinion on Biological Therapy 18:11, pages 1159-1170.
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Neha Kamran, Alexandra Calinescu, Marianela Candolfi, Mayuri Chandran, Yohei Mineharu, Antonela S. Asad, Carl Koschmann, Felipe J. Nunez, Pedro R. Lowenstein & Maria G. Castro. (2016) Recent advances and future of immunotherapy for glioblastoma. Expert Opinion on Biological Therapy 16:10, pages 1245-1264.
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Matías Garcia Fallit, Matías L. Pidre, Antonela S. Asad, Jorge A. Peña Agudelo, Mariana B. Vera, Alejandro J. Nicola Candia, Sofia B. Sagripanti, Melanie Pérez Kuper, Leslie C. Amorós Morales, Abril Marchesini, Nazareno Gonzalez, Carla M. Caruso, Víctor Romanowski, Adriana Seilicovich, Guillermo A. Videla-Richardson, Flavia A. Zanetti & Marianela Candolfi. (2023) Evaluation of Baculoviruses as Gene Therapy Vectors for Brain Cancer. Viruses 15:3, pages 608.
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Disha Mittal, Anita Kamra Verma & Indrakant Singh. 2023. Treatment Landscape of Targeted Therapies in Oncology. Treatment Landscape of Targeted Therapies in Oncology 135 164 .
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Haibo Jia & Xiaoxiao Yan. (2022) lncRNA MEG3 Inhibits the Proliferation and Growth of Glioma Cells by Downregulating Bcl-xL in the PI3K/Akt/NF-κB Signal Pathway. BioMed Research International 2022, pages 1-10.
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Andrea Comba, Syed M. Faisal, Maria Luisa Varela, Todd Hollon, Wajd N. Al-Holou, Yoshie Umemura, Felipe J. Nunez, Sebastien Motsch, Maria G. Castro & Pedro R. Lowenstein. (2021) Uncovering Spatiotemporal Heterogeneity of High-Grade Gliomas: From Disease Biology to Therapeutic Implications. Frontiers in Oncology 11.
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Naveen Sharma, Eun-Joo Shin, Duc Toan Pham, Garima Sharma, Duy-Khanh Dang, Chu Xuan Duong, Sang Won Kang, Seung-Yeol Nah, Choon-Gon Jang, Xin Gen Lei, Toshitaka Nabeshima, Guoying Bing, Ji Hoon Jeong & Hyoung-Chun Kim. (2021) GPx-1-encoded adenoviral vector attenuates dopaminergic impairments induced by methamphetamine in GPx-1 knockout mice through modulation of NF-κB transcription factor. Food and Chemical Toxicology 154, pages 112313.
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Yogesh R. Suryawanshi & Autumn J. Schulze. (2021) Oncolytic Viruses for Malignant Glioma: On the Verge of Success?. Viruses 13:7, pages 1294.
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Junhe Zhang, Hao Chen, Chen Chen, Haimeng Liu, Yurou He, Junli Zhao, Peiyan Yang, Qinwen Mao & Haibin Xia. (2021) Systemic administration of mesenchymal stem cells loaded with a novel oncolytic adenovirus carrying IL-24/endostatin enhances glioma therapy. Cancer Letters 509, pages 26-38.
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Mahmoud S. Alghamri, Brandon L. McClellan, Carson S. Hartlage, Santiago Haase, Syed Mohd Faisal, Rohit Thalla, Ali Dabaja, Kaushik Banerjee, Stephen V. Carney, Anzar A. Mujeeb, Michael R. Olin, James J. Moon, Anna Schwendeman, Pedro R. Lowenstein & Maria G. Castro. (2021) Targeting Neuroinflammation in Brain Cancer: Uncovering Mechanisms, Pharmacological Targets, and Neuropharmaceutical Developments. Frontiers in Pharmacology 12.
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Junsheng Li, Wen Wang, Jia Wang, Yong Cao, Shuo Wang & Jizong Zhao. (2021) Viral Gene Therapy for Glioblastoma Multiforme: A Promising Hope for the Current Dilemma. Frontiers in Oncology 11.
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Jessica M. Rosin, Candace M. Marsters, Faizan Malik, Rena Far, Lata Adnani, Carol Schuurmans, Quentin J. Pittman & Deborah M. Kurrasch. (2021) Embryonic Microglia Interact with Hypothalamic Radial Glia during Development and Upregulate the TAM Receptors MERTK and AXL following an Insult. Cell Reports 34:1, pages 108587.
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Sanyog Jain, Kaisar Raza, Ashish Kumar Agrawal & Ankur Vaidya. 2021. Nanotechnology Applications for Cancer Chemotherapy. Nanotechnology Applications for Cancer Chemotherapy 439 484 .
Flor Mendez, Padma Kadiyala, Felipe J. Nunez, Stephen Carney, Fernando M. Nunez, Jessica C. Gauss, Ramya Ravindran, Sheeba Pawar, Marta Edwards, Maria Belen Garcia-Fabiani, Santiago Haase, Pedro R. Lowenstein & Maria G. Castro. (2020) Therapeutic Efficacy of Immune Stimulatory Thymidine Kinase and fms-like Tyrosine Kinase 3 Ligand (TK/Flt3L) Gene Therapy in a Mouse Model of High-Grade Brainstem Glioma. Clinical Cancer Research 26:15, pages 4080-4092.
Crossref
Ceera Manikandan, Akshita Kaushik & Dwaipayan Sen. (2019) Viral vector: potential therapeutic for glioblastoma multiforme. Cancer Gene Therapy 27:5, pages 270-279.
Crossref
Brittanie Partridge & John H. RossmeislJr.Jr.. (2020) Companion animal models of neurological disease. Journal of Neuroscience Methods 331, pages 108484.
Crossref
Flavia De Carlo, Litty Thomas, Bell Brooke, Elliot T. Varney, Rounak Nande, Olivia Boskovic, Gailen D. Marshall, Pier Paolo Claudio & Candace M. Howard. (2019) Microbubble-mediated delivery of human adenoviruses does not elicit innate and adaptive immunity response in an immunocompetent mouse model of prostate cancer. Journal of Translational Medicine 17:1.
Crossref
Jian Meng, Jing-guang Zhang, Song-tao Du & Ning Li. (2018) The effect of gene therapy on postoperative recurrence of small hepatocellular carcinoma (less than 5cm). Cancer Gene Therapy 26:3-4, pages 114-117.
Crossref
Wing-Fu Lai. 2019. Delivery of Therapeutics for Biogerontological Interventions. Delivery of Therapeutics for Biogerontological Interventions 25 36 .
Kewal K. Jain. (2018) A Critical Overview of Targeted Therapies for Glioblastoma. Frontiers in Oncology 8.
Crossref
Zhi-Wei Tao & Ping-An Zou. (2018) Adenovirus-mediated small interfering RNA targeting ezrin induces apoptosis and inhibits metastasis of human osteosarcoma MG-63 cells. Bioscience Reports 38:4.
Crossref
Wojciech K. Panek, J. Robert Kane, Jacob S. Young, Aida Rashidi, Julius W. Kim, Deepak Kanojia & Maciej S. Lesniak. (2017) Hitting the nail on the head: combining oncolytic adenovirus-mediated virotherapy and immunomodulation for the treatment of glioma. Oncotarget 8:51, pages 89391-89405.
Crossref
Gundula Sprick, Tobias Weidner, Denise Salzig & Peter Czermak. (2017) Baculovirus-induced recombinant protein expression in human mesenchymal stromal stem cells: A promoter study. New Biotechnology 39, pages 161-166.
Crossref
Yusuf Tufail, Daniela Cook, Lawrence Fourgeaud, Colin J. Powers, Katharina Merten, Charles L. Clark, Elizabeth Hoffman, Alexander Ngo, Kohei J. Sekiguchi, Clodagh C. O’Shea, Greg Lemke & Axel Nimmerjahn. (2017) Phosphatidylserine Exposure Controls Viral Innate Immune Responses by Microglia. Neuron 93:3, pages 574-586.e8.
Crossref
Martin J. Hicks, Maria J. Chiuchiolo, Douglas Ballon, Jonathan P. Dyke, Eric Aronowitz, Kosuke Funato, Viviane Tabar, David Havlicek, Fan Fan, Dolan Sondhi, Stephen M. Kaminsky & Ronald G. Crystal. (2016) Anti-Epidermal Growth Factor Receptor Gene Therapy for Glioblastoma. PLOS ONE 11:10, pages e0162978.
Crossref
Nathan VanderVeenNicholas RajaElizabeth YiHenry AppelmanPhilip NgDonna PalmerDaniel ZamlerMarta DzamanPedro R. LowensteinMaria G. Castro. (2016) Preclinical Efficacy and Safety Profile of Allometrically Scaled Doses of Doxycycline Used to Turn “On” Therapeutic Transgene Expression from High-Capacity Adenoviral Vectors in a Glioma Model. Human Gene Therapy Methods 27:3, pages 98-111.
Crossref
Jinhwan Kim, Jihoon Kim, Cherlhyun Jeong & Won Jong Kim. (2016) Synergistic nanomedicine by combined gene and photothermal therapy. Advanced Drug Delivery Reviews 98, pages 99-112.
Crossref
Timothy Weixin Kwang, Xinhui Zeng & Shu Wang. (2016) Manufacturing of AcMNPV baculovirus vectors to enable gene therapy trials. Molecular Therapy - Methods & Clinical Development 3, pages 15050.
Crossref
Ashim K. Mitra, Vibhuti Agrahari, Abhirup Mandal, Kishore Cholkar, Chandramouli Natarajan, Sujay Shah, Mary Joseph, Hoang M. Trinh, Ravi Vaishya, Xiaoyan Yang, Yi Hao, Varun Khurana & Dhananjay Pal. (2015) Novel delivery approaches for cancer therapeutics. Journal of Controlled Release 219, pages 248-268.
Crossref
Caiyun Xu & Hong Zhang. (2015) Somatostatin Receptor Based Imaging and Radionuclide Therapy. BioMed Research International 2015, pages 1-14.
Crossref

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