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Paradigm shift in activity assessment of IgA nephropathy – optimizing the next generation of diagnostic and therapeutic maneuvers via glycan targeting

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Martina Dicker, Daniel Maresch & Richard Strasser. (2016) Glyco-engineering for the production of recombinant IgA1 with distinct mucin-type O-glycans in plants. Bioengineered 7:6, pages 484-489.
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Alexandra Cambier, Patrick J. Gleeson, Héloise Flament, Marie-Bénédicte Le Stang & Renato C. Monteiro. (2020) New therapeutic perspectives for IgA nephropathy in children. Pediatric Nephrology 36:3, pages 497-506.
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Andreas Loos & Herta Steinkellner. 2018. Molecular Pharming. Molecular Pharming 217 229 .
Rosanna Coppo. (2016) Biomarkers and targeted new therapies for IgA nephropathy. Pediatric Nephrology 32:5, pages 725-731.
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Masahiro Muto, Benoit Manfroi, Hitoshi Suzuki, Kensuke Joh, Masaaki Nagai, Sachiko Wakai, Christian Righini, Masayuki Maiguma, Shozo Izui, Yasuhiko Tomino, Bertrand Huard & Yusuke Suzuki. (2017) Toll-Like Receptor 9 Stimulation Induces Aberrant Expression of a Proliferation-Inducing Ligand by Tonsillar Germinal Center B Cells in IgA Nephropathy. Journal of the American Society of Nephrology 28:4, pages 1227-1238.
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F M Rasche, F Keller, W G Rasche, S Schiekofer, A Boldt, U Sack & J Fahnert. (2016) Why, when and how should immunosuppressive therapy considered in patients with immunoglobulin A nephropathy?. Clinical and Experimental Immunology 186:2, pages 115-133.
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Tsai-Jung Lin, Sung-Sen Yang, Kuo-Feng Hua, Yu-Ling Tsai, Shih-Hua Lin & Shuk-Man Ka. (2016) SPAK plays a pathogenic role in IgA nephropathy through the activation of NF-κB/MAPKs signaling pathway. Free Radical Biology and Medicine 99, pages 214-224.
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Martina Dicker, Marc Tschofen, Daniel Maresch, Julia König, Paloma Juarez, Diego Orzaez, Friedrich Altmann, Herta Steinkellner & Richard Strasser. (2016) Transient Glyco-Engineering to Produce Recombinant IgA1 with Defined N- and O-Glycans in Plants. Frontiers in Plant Science 7.
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Kyoko Watanabe & Keita Hirano. 2016. Pathogenesis and Treatment in IgA Nephropathy. Pathogenesis and Treatment in IgA Nephropathy 303 309 .

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