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Expert Opinion on Biological Therapy Volume 15, 2015 - Issue 3
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Drug Evaluation

Genetically modified chondrocytes expressing TGF-β1: a revolutionary treatment for articular cartilage damage?

Randa K ElmallahRubin Institute for Advanced Orthopedics, Sinai Hospital of Baltimore, Center for Joint Preservation and Replacement, 2401 West Belvedere Avenue, Baltimore, MD 21215, USA+1 410 601 8500; +1 410 601 8501; [email protected]; [email protected]
, MD,
Jeffrey J CherianRubin Institute for Advanced Orthopedics, Sinai Hospital of Baltimore, Center for Joint Preservation and Replacement, 2401 West Belvedere Avenue, Baltimore, MD 21215, USA+1 410 601 8500; +1 410 601 8501; [email protected]; [email protected]
, DO,
Julio J JaureguiRubin Institute for Advanced Orthopedics, Sinai Hospital of Baltimore, Center for Joint Preservation and Replacement, 2401 West Belvedere Avenue, Baltimore, MD 21215, USA+1 410 601 8500; +1 410 601 8501; [email protected]; [email protected]
, MD,
Todd P PierceRubin Institute for Advanced Orthopedics, Sinai Hospital of Baltimore, Center for Joint Preservation and Replacement, 2401 West Belvedere Avenue, Baltimore, MD 21215, USA+1 410 601 8500; +1 410 601 8501; [email protected]; [email protected]
, MD,
Walter B BeaverOrthoCarolina Hip and Knee Center, 2001 Vail Avenue, Charlotte, NC 28207, USA
, MD &
Michael A MontRubin Institute for Advanced Orthopedics, Sinai Hospital of Baltimore, Center for Joint Preservation and Replacement, 2401 West Belvedere Avenue, Baltimore, MD 21215, USA+1 410 601 8500; +1 410 601 8501; [email protected]; [email protected]
, MD
Pages 455-464 | Published online: 03 Feb 2015

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Isabel Andia & Nicola Maffulli. (2018) How far have biological therapies come in regenerative sports medicine?. Expert Opinion on Biological Therapy 18:7, pages 785-793.
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Articles from other publishers (12)

E. S. Vladimirova, V. P. Nikulina, M. A. Godkov & E. A. Kasholkina. (2023) Immunological Aspects of the Pathogenesis of Cicatricial Tracheal Stenosis. Russian Sklifosovsky Journal "Emergency Medical Care" 12:3, pages 428-434.
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Wei Gao, Kai Chen, Wenbao He, Shitong Zhao, Dongming Cui, Chunsheng Tao, Yong Xu, Xiufeng Xiao, Qian Feng & Huitang Xia. (2023) Synergistic chondrogenesis promotion and arthroscopic articular cartilage restoration via injectable dual-drug-loaded sulfated hyaluronic acid hydrogel for stem cell therapy. Composites Part B: Engineering, pages 110857.
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M. S. Bozhokin, Y. V. Sopova, D. V. Kachkin, A. A. Rubel & M. G. Khotin. (2020) Mechanisms of TGFβ3 Action as a Therapeutic Agent for Promoting the Synthesis of Extracellular Matrix Proteins in Hyaline Cartilage. Biochemistry (Moscow) 85:4, pages 436-447.
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Tomas Gonzalez-Fernandez, Daniel J. Kelly & Fergal J. O'Brien. (2018) Controlled Non-Viral Gene Delivery in Cartilage and Bone Repair: Current Strategies and Future Directions. Advanced Therapeutics 1:7, pages 1800038.
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Corey Sermer, Rita Kandel, Jesse Anderson, Mark Hurtig & John Theodoropoulos. (2017) Platelet‐rich plasma enhances the integration of bioengineered cartilage with native tissue in an in vitro model . Journal of Tissue Engineering and Regenerative Medicine 12:2, pages 427-436.
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Chae-Lyul Lim, Yeon-Ju Lee, Jong-Ho Cho, Heonsik Choi, Bumsup Lee, Myung Chul Lee & Sujeong Kim. (2017) Immunogenicity and immunomodulatory effects of the human chondrocytes, hChonJ. BMC Musculoskeletal Disorders 18:1.
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Mellannie P. Stuart, Renata A. M. Matsui, Matheus F. S. Santos, Isis Côrtes, Mayra S. Azevedo, Karina R. Silva, Anderson Beatrici, Paulo Emílio C. Leite, Priscila Falagan-Lotsch, José M. Granjeiro, Vladimir Mironov & Leandra S. Baptista. (2017) Successful Low-Cost Scaffold-Free Cartilage Tissue Engineering Using Human Cartilage Progenitor Cell Spheroids Formed by Micromolded Nonadhesive Hydrogel. Stem Cells International 2017, pages 1-11.
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Yuan Tang, Jun Xiao, Yeyang Wang, Ming Li & Zhanjun Shi. (2017) Effect of adenovirus-mediated TGF-?1 gene transfer on the function of rabbit articular chondrocytes. Journal of Orthopaedic Science 22:1, pages 149-155.
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Magali Cucchiarini & Ana Rey-Rico. 2017. Advances in Biomaterials for Biomedical Applications. Advances in Biomaterials for Biomedical Applications 261 300 .
Alain da Silva Morais, F. Raquel Maia, Rui L. Reis & Joaquim M. Oliveira. 2017. Bio-orthopaedics. Bio-orthopaedics 619 635 .
Jun Sun, Xiao-kui Hou & Yu-xin Zheng. (2016) Restore a 9?mm diameter osteochondral defect with gene enhanced tissue engineering followed mosaicplasty in a goat model. Acta Orthopaedica et Traumatologica Turcica 50:4, pages 464-469.
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Yuankun Dai & Changyou Gao. 2016. Polymeric Biomaterials for Tissue Regeneration. Polymeric Biomaterials for Tissue Regeneration 255 287 .

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