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Atoh1 gene therapy in the cochlea for hair cell regeneration

, PhD (Senior Research Fellow) & , PhD (Post-Doctoral Fellow)

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Yongli Zhang, Qi Tang, Ruoyan Xue, Juanjuan Gao, Hua Yang, Zhiqiang Gao & Gan Lin. (2018) Absence of Atoh1 induced partially different cell fates of cochlear and vestibular sensory epithelial cells in mice. Acta Oto-Laryngologica 138:11, pages 972-976.
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Articles from other publishers (35)

Aida Costa, Lynn M. Powell, Mattias Malaguti, Abdenour Soufi, Sally Lowell & Andrew P. Jarman. (2022) Repurposing the lineage-determining transcription factor Atoh1 without redistributing its genomic binding sites. Frontiers in Cell and Developmental Biology 10.
Crossref
Jianyong Chen, Dekun Gao, Lianhua Sun & Jun Yang. (2022) Kölliker’s organ-supporting cells and cochlear auditory development. Frontiers in Molecular Neuroscience 15.
Crossref
Ming Li, Yurong Mu, Hua Cai, Han Wu & Yanyan Ding. (2022) Application of New Materials in Auditory Disease Treatment. Frontiers in Cellular Neuroscience 15.
Crossref
Zhenhang Xu, Vikrant Rai & Jian Zuo. (2021) TUB and ZNF532 Promote the Atoh1-Mediated Hair Cell Regeneration in Mouse Cochleae. Frontiers in Cellular Neuroscience 15.
Crossref
Samira Ajdari, Javad Saffari-Chaleshtori, Zahra Pourteymourfard-Tabrizi, Payam Ghasemi-Dehkordi, Mahdi Ghatreh Samani, Majid Validi, Hamidreza Kabiri, Morteza Hashemzadeh Chaleshtori & Mohammad-Saeid Jami. (2021) Rare mutations in Atoh1 lead to hearing loss. Gene Reports 24, pages 101254.
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Stella Tsai, Kuender Yang, Kuang-Hsi Chang, Frank Lin, Ruey-Hwang Chou, Min-Chih Li, Ching-Chang Cheng, Chien-Yu Kao, Chie-Pein Chen, Hung-Ching Lin & Yi-Chao Hsu. (2021) Umbilical Cord Mesenchymal Stromal Cell-Derived Exosomes Rescue the Loss of Outer Hair Cells and Repair Cochlear Damage in Cisplatin-Injected Mice. International Journal of Molecular Sciences 22:13, pages 6664.
Crossref
Aida Nourbakhsh, Brett M. Colbert, Eric Nisenbaum, Aziz El-Amraoui, Derek M. Dykxhoorn, Karl Russell Koehler, Zheng-yi Chen & Xue Z. Liu. (2021) Stem Cells and Gene Therapy in Progressive Hearing Loss: the State of the Art. Journal of the Association for Research in Otolaryngology 22:2, pages 95-105.
Crossref
Marta Roccio. (2021) Directed differentiation and direct reprogramming: Applying stem cell technologies to hearing research. Stem Cells 39:4, pages 375-388.
Crossref
Joaquín Guerra Gómez & Jesús Devesa. (2021) Growth Hormone and the Auditory Pathway: Neuromodulation and Neuroregeneration. International Journal of Molecular Sciences 22:6, pages 2829.
Crossref
Laura Sumner, Jonathan Mestel & Tobias Reichenbach. (2021) Steady streaming as a method for drug delivery to the inner ear. Scientific Reports 11:1.
Crossref
Marta Roccio, Pascal Senn & Stefan Heller. (2020) Novel insights into inner ear development and regeneration for targeted hearing loss therapies. Hearing Research 397, pages 107859.
Crossref
L HE, J-Y GUO, K LIU, G-P WANG & S-S GONG. (2020) Research Progress on Flat Epithelium of the Inner Ear. Physiological Research, pages 775-785.
Crossref
Zhen Zhang, Jiping Wang, Chunyan Li, Wenyue Xue, Yazhi Xing & Feng Liu. (2020) Gene therapy development in hearing research in China. Gene Therapy 27:7-8, pages 349-359.
Crossref
Kate M. Brody, Amy J. Hampson, Hyun-jung Cho, Prudence Johnson & Stephen J. O’Leary. (2020) A new method for three-dimensional immunofluorescence study of the cochlea. Hearing Research 392, pages 107956.
Crossref
Joaquin E. Jimenez, Aida Nourbakhsh, Brett Colbert, Rahul Mittal, Denise Yan, Carlos L. Green, Eric Nisenbaum, George Liu, Nicole Bencie, Jason Rudman, Susan H. Blanton & Xue Zhong Liu. (2020) Diagnostic and therapeutic applications of genomic medicine in progressive, late-onset, nonsyndromic sensorineural hearing loss. Gene 747, pages 144677.
Crossref
Louise Menendez, Talon Trecek, Suhasni Gopalakrishnan, Litao Tao, Alexander L Markowitz, Haoze V Yu, Xizi Wang, Juan Llamas, Chichou Huang, James Lee, Radha Kalluri, Justin Ichida & Neil Segil. (2020) Generation of inner ear hair cells by direct lineage conversion of primary somatic cells. eLife 9.
Crossref
Shikha Tarang, Umesh Pyakurel, Michael D. Weston, Sarath Vijayakumar, Timothy Jones, Kay-Uwe Wagner & Sonia M. Rocha-Sanchez. (2020) Spatiotemporally controlled overexpression of cyclin D1 triggers generation of supernumerary cells in the postnatal mouse inner ear. Hearing Research 390, pages 107951.
Crossref
Sonja Kleinlogel, Christian Vogl, Marcus Jeschke, Jakob Neef & Tobias Moser. (2020) Emerging approaches for restoration of hearing and vision. Physiological Reviews.
Crossref
Rachael T. Richardson & Niliksha Gunewardene. 2020. The Senses: A Comprehensive Reference. The Senses: A Comprehensive Reference 962 984 .
Nicolas Daudet & Magdalena Żak. 2020. Notch Signaling in Embryology and Cancer. Notch Signaling in Embryology and Cancer 129 157 .
Rick P. C. Cousins. (2019) Medicines discovery for auditory disorders: Challenges for industry. The Journal of the Acoustical Society of America 146:5, pages 3652-3667.
Crossref
Kun Hou, Hui Jiang, Md. Rezaul Karim, Chao Zhong, Zhouwen Xu, Lin Liu, Minxin Guan, Jianzhong Shao & Xiao Huang. (2019) A Critical E-box in Barhl1 3′ Enhancer Is Essential for Auditory Hair Cell Differentiation. Cells 8:5, pages 458.
Crossref
Kristjan R Jessen & Peter Arthur-Farraj. (2019) Repair Schwann cell update: Adaptive reprogramming, EMT, and stemness in regenerating nerves. Glia 67:3, pages 421-437.
Crossref
Yen-Fu Cheng. (2017) Atoh1 regulation in the cochlea: more than just transcriptionAtoh1 转录因子在耳蜗内的转译后调节. Journal of Zhejiang University-SCIENCE B 20:2, pages 146-155.
Crossref
M. Diensthuber & T. Stöver. (2018) Strategien für eine regenerative Therapie der SchwerhörigkeitStrategies for a regenerative therapy of hearing loss. German version. HNO 66:3, pages 179-187.
Crossref
M. Diensthuber & T. Stöver. (2018) Strategies for a regenerative therapy of hearing lossStrategien für eine regenerative Therapie der Schwerhörigkeit. HNO 66:S1, pages 39-46.
Crossref
Sungsu LeeHan-Seong JeongHyong-Ho Cho. (2017) Atoh1 as a Coordinator of Sensory Hair Cell Development and Regeneration in the Cochlea. Chonnam Medical Journal 53:1, pages 37.
Crossref
Icilio Cavero & Henry Holzgrefe. (2017) 15th Annual Meeting of the Safety Pharmacology Society: Focus on traditional sensory systems. Journal of Pharmacological and Toxicological Methods 83, pages 55-71.
Crossref
T. Schrepfer & J. Schacht. 2017. Reference Module in Neuroscience and Biobehavioral Psychology. Reference Module in Neuroscience and Biobehavioral Psychology.
Jos J. Eggermont. 2017. Hearing Loss. Hearing Loss 367 376 .
Simona Chera & Pedro L Herrera. (2016) Regeneration of pancreatic insulin-producing cells by in situ adaptive cell conversion. Current Opinion in Genetics & Development 40, pages 1-10.
Crossref
Magdalena Żak, Cynthia A. van der Linden, Aren Bezdjian, Ferry G. Hendriksen, Sjaak F.L. Klis & Wilko Grolman. (2016) Scar formation in mice deafened with kanamycin and furosemide. Microscopy Research and Technique 79:8, pages 766-772.
Crossref
Colleen G. Le Prell & Edward Lobarinas. 2016. Translational Research in Audiology, Neurotology, and the Hearing Sciences. Translational Research in Audiology, Neurotology, and the Hearing Sciences 1 17 .
Kristjan?R. Jessen, Rhona Mirsky & Peter Arthur-Farraj. (2015) The Role of Cell Plasticity in Tissue Repair: Adaptive Cellular Reprogramming. Developmental Cell 34:6, pages 613-620.
Crossref
Kyoung Ho Park. (2015) Regenerative Cell Therapy for the Sensorineural Hearing Loss. Hanyang Medical Reviews 35:2, pages 113.
Crossref

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