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Expert Opinion on Biological Therapy Volume 15, 2015 - Issue 6
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Original Research

Malignant potential in pancreatic neoplasm; new insights provided by circulating miR-223 in plasma

Shuhei KomatsuKyoto Prefectural University of Medicine, Division of Digestive Surgery, Department of Surgery, 465 Kajii-cho, Kawaramachihirokoji, Kamigyo-ku, Kyoto, Japan+81 75 251 5527; +81 75 251 5522; [email protected]
, MD PhD,
Daisuke IchikawaKyoto Prefectural University of Medicine, Division of Digestive Surgery, Department of Surgery, 465 Kajii-cho, Kawaramachihirokoji, Kamigyo-ku, Kyoto, Japan+81 75 251 5527; +81 75 251 5522; [email protected]
,
Mahito MiyamaeKyoto Prefectural University of Medicine, Division of Digestive Surgery, Department of Surgery, 465 Kajii-cho, Kawaramachihirokoji, Kamigyo-ku, Kyoto, Japan+81 75 251 5527; +81 75 251 5522; [email protected]
,
Tsutomu KawaguchiKyoto Prefectural University of Medicine, Division of Digestive Surgery, Department of Surgery, 465 Kajii-cho, Kawaramachihirokoji, Kamigyo-ku, Kyoto, Japan+81 75 251 5527; +81 75 251 5522; [email protected]
,
Ryo MorimuraKyoto Prefectural University of Medicine, Division of Digestive Surgery, Department of Surgery, 465 Kajii-cho, Kawaramachihirokoji, Kamigyo-ku, Kyoto, Japan+81 75 251 5527; +81 75 251 5522; [email protected]
,
Shoji HirajimaKyoto Prefectural University of Medicine, Division of Digestive Surgery, Department of Surgery, 465 Kajii-cho, Kawaramachihirokoji, Kamigyo-ku, Kyoto, Japan+81 75 251 5527; +81 75 251 5522; [email protected]
,
Wataru OkajimaKyoto Prefectural University of Medicine, Division of Digestive Surgery, Department of Surgery, 465 Kajii-cho, Kawaramachihirokoji, Kamigyo-ku, Kyoto, Japan+81 75 251 5527; +81 75 251 5522; [email protected]
,
Takuma OhashiKyoto Prefectural University of Medicine, Division of Digestive Surgery, Department of Surgery, 465 Kajii-cho, Kawaramachihirokoji, Kamigyo-ku, Kyoto, Japan+81 75 251 5527; +81 75 251 5522; [email protected]
,
Taisuke ImamuraKyoto Prefectural University of Medicine, Division of Digestive Surgery, Department of Surgery, 465 Kajii-cho, Kawaramachihirokoji, Kamigyo-ku, Kyoto, Japan+81 75 251 5527; +81 75 251 5522; [email protected]
,
Hirotaka KonishiKyoto Prefectural University of Medicine, Division of Digestive Surgery, Department of Surgery, 465 Kajii-cho, Kawaramachihirokoji, Kamigyo-ku, Kyoto, Japan+81 75 251 5527; +81 75 251 5522; [email protected]
,
Atsushi ShiozakiKyoto Prefectural University of Medicine, Division of Digestive Surgery, Department of Surgery, 465 Kajii-cho, Kawaramachihirokoji, Kamigyo-ku, Kyoto, Japan+81 75 251 5527; +81 75 251 5522; [email protected]
,
Hisashi IkomaKyoto Prefectural University of Medicine, Division of Digestive Surgery, Department of Surgery, 465 Kajii-cho, Kawaramachihirokoji, Kamigyo-ku, Kyoto, Japan+81 75 251 5527; +81 75 251 5522; [email protected]
,
Kazuma OkamotoKyoto Prefectural University of Medicine, Division of Digestive Surgery, Department of Surgery, 465 Kajii-cho, Kawaramachihirokoji, Kamigyo-ku, Kyoto, Japan+81 75 251 5527; +81 75 251 5522; [email protected]
,
Hiroki TaniguchiDepartment of Surgery, Kyoto Second Red Cross Hospital, 355-5 Kamanzadoori Marutamachi Haruobicho, Kamigyo-ku, 602-8026, Kyoto, Japan
&
Eigo OtsujiKyoto Prefectural University of Medicine, Division of Digestive Surgery, Department of Surgery, 465 Kajii-cho, Kawaramachihirokoji, Kamigyo-ku, Kyoto, Japan+81 75 251 5527; +81 75 251 5522; [email protected]
 show all
Pages 773-785 | Published online: 30 Mar 2015

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Jinru Xue, Erna Jia, Na Ren, Andrew Lindsay & Haixin Yu. (2019) Circulating microRNAs as promising diagnostic biomarkers for pancreatic cancer: a systematic review. OncoTargets and Therapy 12, pages 6665-6684.
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Le Ren & Yue Yu. (2018) The role of miRNAs in the diagnosis, chemoresistance, and prognosis of pancreatic ductal adenocarcinoma. Therapeutics and Clinical Risk Management 14, pages 179-187.
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Yunfeng Zhang, Jinbo Lin, Wenjie Huang, Yong Cao, Yi Liu, Tieqiang Wang, Weiyi Zhong, Dongli Wang, Rongrong Mao & Xiaoliang Chen. (2017) The effect of circulating miR-223 on surveillance of different cancers: a meta-analysis. OncoTargets and Therapy 10, pages 3193-3201.
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QiuBo Zhang, ShaoJie Chen, LinJuan Zeng, YinTing Chen, GuoDa Lian, ChenChen Qian, JiaJia Li, RuiJie Xie & Kai-Hong Huang. (2017) New developments in the early diagnosis of pancreatic cancer. Expert Review of Gastroenterology & Hepatology 11:2, pages 149-156.
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Maria João Amaral, Rui Caetano Oliveira, Paulo Donato & José Guilherme Tralhão. (2023) Pancreatic Cancer Biomarkers: Oncogenic Mutations, Tissue and Liquid Biopsies, and Radiomics—A Review. Digestive Diseases and Sciences 68:7, pages 2811-2823.
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Valeria Tonini & Manuel Zanni. (2022) Early diagnosis of pancreatic cancer: What strategies to avoid a foretold catastrophe. World Journal of Gastroenterology 28:31, pages 4235-4248.
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Jinshou Yang, Ruiyuan Xu, Chengcheng Wang, Jiangdong Qiu, Bo Ren & Lei You. (2021) Early screening and diagnosis strategies of pancreatic cancer: a comprehensive review. Cancer Communications 41:12, pages 1257-1274.
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Shaoshan Mai & Iwona Inkielewicz-Stepniak. (2021) Pancreatic Cancer and Platelets Crosstalk: A Potential Biomarker and Target. Frontiers in Cell and Developmental Biology 9.
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Robert S O'Neill & Alina Stoita. (2021) Biomarkers in the diagnosis of pancreatic cancer: Are we closer to finding the golden ticket?. World Journal of Gastroenterology 27:26, pages 4045-4087.
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Nenggang Zhang, Luiza E. Coutinho & Debananda Pati. (2021) PDS5A and PDS5B in Cohesin Function and Human Disease. International Journal of Molecular Sciences 22:11, pages 5868.
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Victoria Heredia-Soto, Nuria Rodríguez-Salas & Jaime Feliu. (2021) Liquid Biopsy in Pancreatic Cancer: Are We Ready to Apply It in the Clinical Practice?. Cancers 13:8, pages 1986.
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Amir Hossein Aalami, Hossein Abdeahad, Mohammad Mesgari & Amirhossein Sahebkar. (2020) MicroRNA‐223 in gastrointestinal cancers: A systematic review and diagnostic meta‐analysis. European Journal of Clinical Investigation 51:2.
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Nan Yi, Xuying Zhao, Jie Ji, Minxue Xu, Yujie Jiao, Tianyang Qian, Shengze Zhu, Feng Jiang, Jianhua Chen & Mingbing Xiao. (2020) Serum galectin‐3 as a biomarker for screening, early diagnosis, prognosis and therapeutic effect evaluation of pancreatic cancer. Journal of Cellular and Molecular Medicine 24:19, pages 11583-11591.
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Karolina Elżbieta Kaczor-Urbanowicz, Jordan Cheng, Jonathan C. King, Alireza Sedarat, Stephen J. Pandol, James J. Farrell, David T.W. Wong & Yong Kim. (2020) Reviews on Current Liquid Biopsy for Detection and Management of Pancreatic Cancers. Pancreas 49:9, pages 1141-1152.
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Weronika Lucas Grzelczyk, Janusz Szemraj, Sylwia Kwiatkowska & Magdalena Józefowicz-Korczyńska. (2019) Serum expression of selected miRNAs in patients with laryngeal squamous cell carcinoma (LSCC). Diagnostic Pathology 14:1.
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Barbara Pardini, Alexandru Anton Sabo, Giovanni Birolo & George Adrian Calin. (2019) Noncoding RNAs in Extracellular Fluids as Cancer Biomarkers: The New Frontier of Liquid Biopsies. Cancers 11:8, pages 1170.
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Jia Ma, Tong Cao, Yue Cui, Fan Zhang, Ying Shi, Jun Xia & Z Peter Wang. (2019) The miR-223 regulates cell proliferation and invasion via targeting PDS5B in pancreatic cancer cells. Molecular Therapy - Nucleic Acids.
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Yiyin Zhang, Chao Yang, He Cheng, Zhiyao Fan, Qiuyi Huang, Yu Lu, Kun Fan, Guopei Luo, Kaizhou Jin, Zhengshi Wang, Chen Liu & Xianjun Yu. (2018) Novel agents for pancreatic ductal adenocarcinoma: emerging therapeutics and future directions. Journal of Hematology & Oncology 11:1.
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Taisuke Imamura, Shuhei Komatsu, Daisuke Ichikawa, Mahito Miyamae, Wataru Okajima, Takuma Ohashi, Jun Kiuchi, Keiji Nishibeppu, Toshiyuki Kosuga, Hirotaka Konishi, Atsushi Shiozaki, Kazuma Okamoto, Hitoshi Fujiwara & Eigo Otsuji. (2017) Low plasma levels of miR-101 are associated with tumor progression in gastric cancer. Oncotarget 8:63.
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Taisuke Imamura, Shuhei Komatsu, Daisuke Ichikawa, Mahito Miyamae, Wataru Okajima, Takuma Ohashi, Jun Kiuchi, Keiji Nishibeppu, Hirotaka Konishi, Atsushi Shiozaki, Ryo Morimura, Hisashi Ikoma, Toshiya Ochiai, Kazuma Okamoto, Hiroki Taniguchi & Eigo Otsuji. (2017) Depleted tumor suppressor miR-107 in plasma relates to tumor progression and is a novel therapeutic target in pancreatic cancer. Scientific Reports 7:1.
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